Search results for "8a"

showing 10 items of 133 documents

Łojasiewicz exponents, the integral closure of ideals and Newton polyhedra

2003

We give an upper estimate for the Łojasiewicz exponent $\ell(J,I)$ of an ideal $J\subseteq A(K^{n})$ with respect to another ideal I in the ring $A(K^{n})$ of germs analytic functions $f$ : $(K^{n},\mathrm{O})\rightarrow K$ , where $K=C$ or $R$ , using Newton polyhedrons. In particular, we give a method to estimate the Łojasiewicz exponent $\alpha_{0}(f)$ of a germ $f\in A(K^{n})$ that can be applied when $f$ is Newton degenerate with respect to its Newton polyhedron.

58A20Ring (mathematics)32S05General MathematicsDegenerate energy levelsClosure (topology)Łojasiewicz exponentsreal analytic functionsCombinatoricsPolyhedronExponentNewton polyhedronsIdeal (ring theory)Analytic functionMathematicsJournal of the Mathematical Society of Japan
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CCDC 274237: Experimental Crystal Structure Determination

2006

Related Article: G.Stajer, A.E.Szabo, P.Sohar, A.Csampai, R.Sillanpaa|2006|J.Mol.Struct.|784|239|doi:10.1016/j.molstruc.2005.09.011

8a-(4-Chlorophenyl)-78-dihydro-1H-pyrrolo(12-a)pyrimidine-26-dioneSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 749971: Experimental Crystal Structure Determination

2010

Related Article: Y.Rousselin, N.Sok, F.Boschetti, R.Guilard, F.Denat|2010|Eur.J.Org.Chem.|2010|1688|doi:10.1002/ejoc.200901183

8b8c-Dimethyldecahydro-2a4a6a8a-tetraazacyclopenta[fg]acenaphthylene-1-carbonitrileSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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Tumor-Infiltrating Lymphocytes and Response to Neoadjuvant Chemotherapy With or Without Carboplatin in Human Epidermal Growth Factor Receptor 2–Posit…

2015

Purpose Modulation of immunologic interactions in cancer tissue is a promising therapeutic strategy. To investigate the immunogenicity of human epidermal growth factor receptor 2 (HER2) –positive and triple-negative (TN) breast cancers (BCs), we evaluated tumor-infiltrating lymphocytes (TILs) and immunologically relevant genes in the neoadjuvant GeparSixto trial. Patients and Methods GeparSixto investigated the effect of adding carboplatin (Cb) to an anthracycline-plus-taxane combination (PM) on pathologic complete response (pCR). A total of 580 tumors were evaluated before random assignment for stromal TILs and lymphocyte-predominant BC (LPBC). mRNA expression of immune-activating (CXCL9, …

AdultOncologyCancer Researchmedicine.medical_specialtyStromal cellReceptor ErbB-2medicine.medical_treatmentAntineoplastic AgentsTriple Negative Breast NeoplasmsCarboplatinchemistry.chemical_compoundLymphocytes Tumor-InfiltratingPredictive Value of TestsInternal medicineBiomarkers TumormedicineHumansAgedRandomized Controlled Trials as TopicChemotherapybusiness.industryTumor-infiltrating lymphocytesCancerFOXP3Middle AgedPrognosismedicine.diseaseNeoadjuvant TherapyCarboplatin3. Good healthCD8AGene Expression Regulation NeoplasticOncologychemistryChemotherapy AdjuvantCXCL9FemalebusinessJournal of Clinical Oncology
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Products of snowflaked Euclidean lines are not minimal for looking down

2017

We show that products of snowflaked Euclidean lines are not minimal for looking down. This question was raised in Fractured fractals and broken dreams, Problem 11.17, by David and Semmes. The proof uses arguments developed by Le Donne, Li and Rajala to prove that the Heisenberg group is not minimal for looking down. By a method of shortcuts, we define a new distance $d$ such that the product of snowflaked Euclidean lines looks down on $(\mathbb R^N,d)$, but not vice versa.

Ahlfors-regularity26B05 (Primary) 28A80 (Secondary)01 natural sciences010104 statistics & probabilityFractalMathematics - Metric GeometryEuclidean geometryClassical Analysis and ODEs (math.CA)FOS: MathematicsHeisenberg groupMathematics::Metric GeometryBPI-spacesbpi-spacessecondary 28a800101 mathematicsbilipschitz piecesMathematicsDiscrete mathematicsQA299.6-433ahlfors-regularityApplied Mathematics010102 general mathematicsprimary 26b05Metric Geometry (math.MG)biLipschitz piecesMathematics - Classical Analysis and ODEsProduct (mathematics)Geometry and TopologyAnalysis
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Stress concentration for closely located inclusions in nonlinear perfect conductivity problems

2019

We study the stress concentration, which is the gradient of the solution, when two smooth inclusions are closely located in a possibly anisotropic medium. The governing equation may be degenerate of $p-$Laplace type, with $1<p \leq N$. We prove optimal $L^\infty$ estimates for the blow-up of the gradient of the solution as the distance between the inclusions tends to zero.

Applied Mathematics010102 general mathematicsMathematical analysisDegenerate energy levelsZero (complex analysis)Perfect conductorAnalysiGradient blow-upType (model theory)Conductivity01 natural sciences010101 applied mathematicsNonlinear systemMathematics - Analysis of PDEsFOS: MathematicsFinsler p-Laplacian0101 mathematicsPerfect conductorAnisotropy35J25 35B44 35B50 (Primary) 35J62 78A48 58J60 (Secondary)AnalysisAnalysis of PDEs (math.AP)MathematicsStress concentration
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Singular integrals on regular curves in the Heisenberg group

2019

Let $\mathbb{H}$ be the first Heisenberg group, and let $k \in C^{\infty}(\mathbb{H} \, \setminus \, \{0\})$ be a kernel which is either odd or horizontally odd, and satisfies $$|\nabla_{\mathbb{H}}^{n}k(p)| \leq C_{n}\|p\|^{-1 - n}, \qquad p \in \mathbb{H} \, \setminus \, \{0\}, \, n \geq 0.$$ The simplest examples include certain Riesz-type kernels first considered by Chousionis and Mattila, and the horizontally odd kernel $k(p) = \nabla_{\mathbb{H}} \log \|p\|$. We prove that convolution with $k$, as above, yields an $L^{2}$-bounded operator on regular curves in $\mathbb{H}$. This extends a theorem of G. David to the Heisenberg group. As a corollary of our main result, we infer that all …

Applied MathematicsGeneral Mathematics42B20 (primary) 43A80 28A75 35R03 (secondary)Metric Geometry (math.MG)Singular integralLipschitz continuityuniform rectifiabilityHeisenberg groupFunctional Analysis (math.FA)ConvolutionBounded operatorMathematics - Functional AnalysisCombinatoricsMathematics - Metric GeometryMathematics - Classical Analysis and ODEsBounded functionClassical Analysis and ODEs (math.CA)FOS: MathematicsHeisenberg groupsingular integralsBoundary value problemKernel (category theory)MathematicsJournal de Mathématiques Pures et Appliquées
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Dimension estimates for the boundary of planar Sobolev extension domains

2020

We prove an asymptotically sharp dimension upper-bound for the boundary of bounded simply-connected planar Sobolev $W^{1,p}$-extension domains via the weak mean porosity of the boundary. The sharpness of our estimate is shown by examples.

Applied MathematicsMathematical analysisBoundary (topology)Extension (predicate logic)Physics::Classical PhysicsFunctional Analysis (math.FA)Sobolev spaceMathematics - Functional AnalysisPlanarDimension (vector space)46E35 28A75Mathematics - Classical Analysis and ODEsBounded functionClassical Analysis and ODEs (math.CA)FOS: MathematicsAnalysisMathematics
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Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature.

2009

Abstract Tumors may be initiated and maintained by a cellular subcomponent that displays stem cell properties. We have used the expression of aldehyde dehydrogenase as assessed by the ALDEFLUOR assay to isolate and characterize cancer stem cell (CSC) populations in 33 cell lines derived from normal and malignant mammary tissue. Twenty-three of the 33 cell lines contained an ALDEFLUOR-positive population that displayed stem cell properties in vitro and in NOD/SCID xenografts. Gene expression profiling identified a 413-gene CSC profile that included genes known to play a role in stem cell function, as well as genes such as CXCR1/IL-8RA not previously known to play such a role. Recombinant int…

Cancer ResearchPathologymedicine.medical_specialtyCellular differentiation[SDV.CAN]Life Sciences [q-bio]/CancerBreast Neoplasms[SDV.BC]Life Sciences [q-bio]/Cellular BiologyMice SCIDBiologyStem cell markerArticleCell LineReceptors Interleukin-8AMetastasisMice03 medical and health sciences0302 clinical medicineMice Inbred NODCancer stem cellCell Line TumorBiomarkers TumormedicineAnimalsHomeostasisHumansBreastRNA MessengerRNA NeoplasmNeoplasm MetastasisOligonucleotide Array Sequence Analysis030304 developmental biologySettore MED/04 - Patologia Generale0303 health sciencesReverse Transcriptase Polymerase Chain ReactionGene Expression ProfilingStem CellsCancerAldehyde DehydrogenaseFlow Cytometrymedicine.disease3. Good healthOncologyCell culture030220 oncology & carcinogenesisCancer researchFemaleStem cellImmortalised cell lineAldefluor breast cancer cell
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Uniformization with infinitesimally metric measures

2019

We consider extensions of quasiconformal maps and the uniformization theorem to the setting of metric spaces $X$ homeomorphic to $\mathbb R^2$. Given a measure $\mu$ on such a space, we introduce $\mu$-quasiconformal maps $f:X \to \mathbb R^2$, whose definition involves deforming lengths of curves by $\mu$. We show that if $\mu$ is an infinitesimally metric measure, i.e., it satisfies an infinitesimal version of the metric doubling measure condition of David and Semmes, then such a $\mu$-quasiconformal map exists. We apply this result to give a characterization of the metric spaces admitting an infinitesimally quasisymmetric parametrization.

Characterization (mathematics)Space (mathematics)conformal modulus01 natural sciencesMeasure (mathematics)funktioteoriaCombinatoricsMathematics - Metric Geometry0103 physical sciencesFOS: Mathematics0101 mathematicsComplex Variables (math.CV)MathematicsMathematics - Complex VariablesMathematics::Complex Variables010102 general mathematicsquasiconformal mappingMetric Geometry (math.MG)metriset avaruudetmetric doubling measureMetric spaceDifferential geometryUniformization theoremMetric (mathematics)quasisymmetric mapping30L10 (Primary) 30C65 28A75 51F99 (Secondary)mittateoria010307 mathematical physicsGeometry and TopologyUniformization (set theory)
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