Search results for "A2"

showing 10 items of 1101 documents

Polymorphonuclear leukocyte rheology, cytosolic Ca2+ content, beta2-integrin expression and oxidative stress in hypertension.

2008

Hypertension Leukocyte rheology beta2-integrin oxidative stress.
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Protection by beverages, fruits, vegetables, herbs, and flavonoids against genotoxicity of 2-acetylaminofluorene and 2-amino-1-methyl-6-phenylimidazo…

2002

Abstract Chinese hamster lung fibroblasts, genetically engineered for the expression of rat cytochrome P450 dependent monooxygenase 1A2 and rat sulfotransferase 1C1 (V79-rCYP1A2-rSULT1C1 cells), were utilized to check for possible protective effects of beverages of plant origin, fruits, vegetables, and spices against genotoxicity induced by 2-acetylaminofluorene (AAF) or 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Antigenotoxic activities of juices from spinach and red beets against AAF could be monitored with similar effectivity by the HPRT-mutagenicity test (IC50=0.64%; 2.57%) and alkaline single cell gel electrophoresis (comet assay; IC50=0.12%; 0.89%) which detects DNA stran…

Hypoxanthine PhosphoribosyltransferaseHealth Toxicology and Mutagenesismedicine.disease_causeCell LineBeverageschemistry.chemical_compoundCricetulusCytochrome P-450 CYP1A2CricetinaeVegetablesGeneticsmedicineAnimalsWineFlavonoids2-Amino-1-methyl-6-phenylimidazo(45-b)pyridinePlants MedicinalbiologyMutagenicity TestsImidazolesfood and beveragesAntimutagenic AgentsMonooxygenase2-AcetylaminofluoreneFibroblastsbiology.organism_classificationRecombinant ProteinsRatsComet assayBiochemistrychemistryWhite WineFruitFlavanonesSpinachQuercetin2-AcetylaminofluoreneComet AssaySulfotransferasesGenotoxicityMutagensMutation research
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Digital Vitruvius, or an elogy of the equilateral triangle

2012

On interpretation of an architectural project, triangle’s form generally refers both to plans of organic architecture and to fronts of Romanesque and Gothic churches. This wonderful form, that contains God’s eye, is, according to Vitruvius, the geometric generative principle of the Roman Theatre. Everybody knows that De Architectura arrived to us without images; in the past there were innumerable interpretations, from editio princeps (1486). A digital transcriptions, that follows side by side a Vitruvius’ book’s translation, highlights the compositional process that defines that the equilateral triangle is the geometric element that give origin to the composition of theatre.

ICAR17 - Disegnostoriarappresentazione digitalerepresentationdigitalhistory; representation; digitalSettore ICAR/17 - Disegnohistorylcsh:Architecturelcsh:NA2695-2793lcsh:Architectural drawing and designstoria; rappresentazione; digitalelcsh:NA1-9428
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RUOLO DELL’IL-13 NELLA DESENSIBILIZZAZIONE DEL RECETTORE beta2 ADRENERGICO NELLE CELLULE EPITELIALI BRONCHIALI PRIMARIE UMANE

2014

IL-13 induced beta2-adrenergic receptor (ß2-AR) desensitization in human airway epithelial cells.

IL-13 recettore beta due adrenergico cellule epiteliali bronchialiIL-13 beta2-adrenergic receptor human airway epithelial cells.
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Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

2015

Contains fulltext : 155360.pdf (Publisher’s version ) (Closed access) Coffee, a major dietary source of caffeine, is among the most widely consumed beverages in the world and has received considerable attention regarding health risks and benefits. We conducted a genome-wide (GW) meta-analysis of predominately regular-type coffee consumption (cups per day) among up to 91,462 coffee consumers of European ancestry with top single-nucleotide polymorphisms (SNPs) followed-up in ~30 062 and 7964 coffee consumers of European and African-American ancestry, respectively. Studies from both stages were combined in a trans-ethnic meta-analysis. Confirmed loci were examined for putative functional and b…

INVOLVEMENTNetherlands Twin Register (NTR)GCKR protein humanPROTEINGenome-wide association studyVARIANTSgenetics [Brain-Derived Neurotrophic Factor]chemistry.chemical_compound0302 clinical medicinePolymorphism (computer science)genetics [Adaptor Proteins Signal Transducing]BINDINGBRAINGenetics0303 health sciencesBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsDisorders of movement Donders Center for Medical Neuroscience [Radboudumc 3]3. Good healthPsychiatry and Mental healthPhenotypegenetics [Polymorphism Single Nucleotide]/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beinggenetics [Cytochrome P-450 CYP1A2]CaffeineCAFFEINESingle-nucleotide polymorphismBiologyArticle03 medical and health sciencesCellular and Molecular NeuroscienceSDG 3 - Good Health and Well-beingCytochrome P-450 CYP1A2/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_SNPHumansddc:610Allelegenetics [Basic Helix-Loop-Helix Leucine Zipper Transcription Factors]Molecular Biology030304 developmental biologyAdaptor Proteins Signal TransducingMLXIPL protein humanRECEPTORBrain-Derived Neurotrophic FactorCoffeata1182Feeding Behaviorbiology.organism_classificationta3124BDNFchemistryBehavioral medicineDevelopmental Psychopathology030217 neurology & neurosurgeryGLUCOKINASEmetabolism [Coffea]Genome-Wide Association StudyMolecular Psychiatry
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Heavy-Ion Radiation Impact on a 4 Mb FRAM Under Different Test Modes and Conditions

2016

International audience; The impact of heavy-ions on commercial Ferroelectric Memories (FRAMs) is analyzed. The influence of dynamic and static test modes as well as several stimuli on the error rate of this memory is investigated. Static test results show that the memory is prone to temporary effects occurring in the peripheral circuitry, with a possible effect due to fluence. Dynamic tests results show a high sensitivity of this memory to switching activity of this peripheral circuitry.

ImaginationNuclear and High Energy PhysicsHeavy ion radiationMaterials science130 nmmedia_common.quotation_subject[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]01 natural sciencesFluence[SPI]Engineering Sciences [physics]0103 physical sciencesStatic testingSensitivity (control systems)Electrical and Electronic Engineeringradiation testingSimulationmedia_common010302 applied physicssingle event upset (SEU)ta114ta213010308 nuclear & particles physicsbusiness.industrymultiple cell upset (MCU)FerroelectricityNon-volatile memoryRadiation testingFRAM130nm technologyNuclear Energy and EngineeringOptoelectronicsbusinessstatic and dynamic mode testingIEEE Transactions on Nuclear Science
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Recognition of human renal cell carcinoma and melanoma by HLA-A2-restricted cytotoxic T lymphocytes is mediated by shared peptide epitopes and up-reg…

1996

Cytotoxic T lymphocytes (CTL) have previously been isolated from peripheral blood of patients with renal cell carcinoma (RCC). The CD8-positive CTL line MZ1257-CTL-5 (CTL-5) has been shown to lyse autologous cultured RCC cells in an HLA-A2 restricted fashion. Allogeneic, HLA-A2-matched RCC and melanoma cell lines were also lysed by CTL-5, suggesting that melanoma and renal cancer share antigenic determinants. The aim of the study was to determine whether RCC and melanoma share peptide epitopes that are recognized by CTL-5 in the context of HLA-A2 molecules. Peptides were acideulated from various cell lines, separated by reversed phase high performance liquid chromatography (RP-HPLC), and as…

ImmunologyCellurologic and male genital diseasesEpitopeEpitopesInterferon-gammaAntigenMHC class IHLA-A2 AntigenmedicineTumor Cells CulturedCytotoxic T cellHumansInterferon gammaCarcinoma Renal CellMelanomaB-LymphocytesbiologyMelanomaGeneral Medicinemedicine.diseaseMolecular biologyUp-RegulationCTL*medicine.anatomical_structurebiology.proteinPeptidesmedicine.drugT-Lymphocytes CytotoxicScandinavian journal of immunology
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Core–Shell Nanorod Columnar Array Combined with Gold Nanoplate–Nanosphere Assemblies Enable Powerful In Situ SERS Detection of Bacteria

2016

Development of a label-free ultrasensitive nanosensor for detection of bacteria is presented. Sensitive assay for Gram-positive bacteria was achieved via electrostatic attraction-guided plasmonic bifacial superstructure/bacteria/columnar array assembled in one step. Dynamic optical hotspots were formed in the hybridized nanoassembly under wet-dry critical state amplifying efficiently the weak vibrational modes of three representative food-borne Gram-positive bacteria, that is, Staphylococcus xylosus, Listeria monocytogenes, and Enterococcus faecium. These three bacteria with highly analogous Raman spectra can be effectively differentiated through droplet wet-dry critical SERS approach combi…

In situMaterials scienceGram-positive bacteriata221Nanotechnology02 engineering and technologySpectrum Analysis Raman010402 general chemistry01 natural sciencessymbols.namesakeNanosensorGeneral Materials Scienceta318PlasmonNanotubesbiology3D PCASERSStaphylococcus xylosusGram-positive bacteria021001 nanoscience & nanotechnologybiology.organism_classificationListeria monocytogenesnanoarray0104 chemical sciencessymbolsNanorodGoldsuperstructure0210 nano-technologyRaman spectroscopyNanospheresBacteriaACS Applied Materials and Interfaces
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Water and carbon oxides on monoclinic zirconia: experimental and computational insights

2014

Zirconium oxide (ZrO2, zirconia) is an interesting catalytic material to be used in biomass conversion, e.g., gasification and reforming. In this work, we show that reducing and hydrating pretreatments affect the surface sites on monoclinic zirconia. The multitechnique approach comprises temperature-programmed surface reactions (TPSR) under CO and CO2 at 100-550 °C, in situ DRIFTS investigations of the surface species and density functional theory (DFT) calculations. The key findings of the work are: (1) formates are formed either directly from gas-phase CO on terminal surface hydroxyls or via the linear CO surface species that are found exclusively on the reduced zirconia without water tre…

In situWork (thermodynamics)ChemistryInorganic chemistryta220General Physics and AstronomyCatalysisCarbon oxideDensity functional theoryCubic zirconiaWater treatmentPhysical and Theoretical Chemistryta216ta215ta116Monoclinic crystal systemPhysical Chemistry Chemical Physics
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"Table 1" of "The spin-dependent structure function g1(x) of the deuteron from polarized deep-inelastic muon scattering."

1997

Measurements of the transverse virtual photon asymmetry A2. Statistical errors only.

InclusiveVirtual Photon AsymmetryNeutral CurrentDeep Inelastic ScatteringPhysics::OpticsHigh Energy Physics::ExperimentNuclear ExperimentMuon productionMU+ DEUT --> MU+ XA2
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