Search results for "ABO"

Compassionate use of meropenem/vaborbactam for infections caused by KPC-producing Klebsiella pneumoniae: a multicentre study

2022

Abstract Objectives To explore the real-life performance of meropenem/vaborbactam for treating serious KPC-producing Klebsiella pneumoniae infections, including those resistant to ceftazidime/avibactam. Methods A retrospective observational cohort study was conducted in 12 Italian hospitals. Enrolled patients had K. pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-Kp) infections (59.5% of which were ceftazidime/avibactam resistant). Patients who received ≥72 h of meropenem/vaborbactam therapy (with or without other antimicrobials) in a compassionate-use setting were included. Results The 37 infections (all hospital-acquired) were mainly bacteraemic (BSIs, n = 23) or lower respira…

Employment effects of reducing labour costs : considering potential bias in macro-estimates of the elasticity of labour demand

2017

In 2016 the Finnish government decided to implement the competitiveness pact in order to increase employment. The objective is to improve cost-competitiveness by lowering labor costs in the private sector. The elasticity of labour demand plays a key role in assessing the employment effects of the competitiveness pact. The idea of this study is based on the Economic Policy Council Report (2016) which argued that the government’s elasticity estimate is very high and predicts overly optimistic employment effects. The majority of studies estimate demand elasticities using aggregate data, which is likely to produce biased estimates. The problems relate in particular to the lack of exogenous vari…

Nutrition supplementation and athletic performance improvement in equestrian athletes of Jumping and Dressage

Anthropometric indices, lipid profile, and lipopolysaccharide-binding protein levels in metabolic endotoxemia: A case-control study in Calabar Metrop…

2020

Objectives: To determine the anthropometric indices, lipopolysaccharide-binding proteins (LBP), and lipid profile in patients with metabolic endotoxemia. Methods: The study comprised of 47 patients with metabolic endotoxemia (the metabolic endotoxemia group) and 43 controls (the control group). Patients in the metabolic endotoxemia group were categorized further into three subgroups including the normal weight group (n=8), the overweight group (n=12) and the obese group (n=27). Height, weight, waist, and hip circumference were measured, and waist-hip ratio (WHR) and body mass index (BMI) were calculated. LBP was determined by ELISA and total cholesterol, triglycerides, high density lipoprot…

Branched-Chain Amino Acid Deprivation Decreases Lipid Oxidation and Lipogenesis in C2C12 Myotubes

2022

Impaired lipid metabolism is a common risk factor underlying several metabolic diseases such as metabolic syndrome and type 2 diabetes. Branched-chain amino acids (BCAAs) that include valine, leucine and isoleucine have been proven to share a role in lipid metabolism and hence in maintaining metabolic health. We have previously introduced a hypothesis suggesting that BCAA degradation mechanistically connects to lipid oxidation and storage in skeletal muscle. To test our hypothesis, the present study examined the effects of BCAA deprivation and supplementation on lipid oxidation, lipogenesis and lipid droplet characteristics in murine C2C12 myotubes. In addition, the role of myotube contract…

Fitness, body composition and blood lipids following three concurrent strength and endurance training modes

2016

This study investigated changes in physical fitness, body composition, and blood lipid profile following 24 weeks of 3 volume-equated concurrent strength and endurance training protocols. Physically active, healthy male and female participants (aged 18–40 years) performed strength and endurance sessions on different days (DD; men, n = 21; women, n = 18) or in the same session with endurance preceding strength (ES; men, n = 16; women, n = 15) or vice versa (SE; men, n = 18; women, n = 14). The training volume was matched in all groups. Maximal leg press strength (1-repetition maximum (1RM)) and endurance performance (maximal oxygen consumption during cycling), body composition (dual-energy X…

Dietary intake and strength training adaptation in 50-70 -year old men and women : with special reference to muscle mass, strength, serum anabolic ho…

2007

Frailty has been defined as an age-related decrease of the physiologic systems that results in weakness, weight loss and decreased functional performance, thus increasing the risk of disability. The physical characteristics of frailty are affected by the amount of muscle mass and strength. Strength training (ST) can alleviate age-related declines in muscle mass, strength and physical function. However, there is controversy regarding whether dietary intake can improve the effects of ST. The present thesis assessed the effects of dietary intake (DI) on muscular, hormonal and metabolic adaptations to ST in healthy 50-70 year old people. In cross-sectional study I, maximal strength of the leg e…

Nikkelin kertyminen täplärapuun (Pacifastacus leniusculus) kahdessa eri lämpötilassa

2017

Kaivostoiminnan aiheuttamat metallipäästöt ovat maailmanlaajuinen ympäristöongelma. Kaivospäästöjen takia metalleja pääsee luontoon ja eliöstöön biosaatavassa vesiliukoisessa muodossa kuten sulfaatteina tai klorideina. Nikkeli on bioakkumuloituva eliöille haitallinen metalli, jota käytetään teollisuuden raaka-aineena ympäri maailmaa. Tässä tutkielmassa tarkasteltiin nikkelin kertymistä täplärapuun (Pacifastacus leniusculus) laboratorio-olosuhteissa kahdella 14 vrk:n altistuskokeella eri nikkelialtistuspitoisuuksilla kahdessa eri lämpötilassa (7 ja 17 °C). Eri testilämpötiloilla pyrittiin selvittämään, onko nikkelin kertyminen riippuvaista vaihtolämpöisen täpläravun aineenvaihduntatasosta. K…

Replacement of fishmeal with corn gluten meal in feeds for juvenile rainbow trout (Oncorhynchus mykiss) does not affect oxygen consumption during for…

2017

We compared oxygen consumption (MO2, mg/kg/h) of c. 80 g rainbow trout (Oncorhynchus mykiss) in an intermittent-flow swim respirometer at 15 °C. Before the tests the fish were grown in flow through tanks (15 °C) with either fishmeal (FM) or corn gluten meal (CGM) based diets (c. 52% protein) for a period of 3–4.5 months. Ten individuals from both treatment groups were fasted for 48 h before the swim test, which consisted of 18 loops of 210 s over three different periods: acclimation period (6 loops at 0.5 body lengths per s, BL/s), exercise period (8 loops at increased speed from 1 to 2.5 BL/s with recovery loops at 0.5 BL/s), and a recovery period (four loops at 0.5 BL/s). We did not obser…

Divergent temperature-specific metabolic and feeding rates of native and invasive crayfish

2022

Temperature is one of the most important factors governing the activity of ectothermic species, and it plays an important but less studied role in the manifestation of invasive species impacts. In this study, we investigated temperature-specific feeding and metabolic rates of invasive and native crayfish, and evaluated how temperature regulates their ecological impacts at present and in future according to different climatic scenarios by bioenergetics modelling. We conducted a series of maximum food consumption experiments and measured the metabolic rates of cold-adapted native noble crayfish (Astacus astacus) and invasive signal crayfish (Pacifastacus leniusculus) originally from a warmer …