Search results for "ACID"
showing 10 items of 13107 documents
Realization of polyaspartamide-based nanoparticles and in vivo lung biodistribution evaluation of a loaded gucocorticoid after aerosolization in mice
2016
Abstract In this study, novel polymeric nanoparticles (NPs) were developed and their potential as carriers for beclomethasone dipropionate (BDP) into the lung after aerosolization was demonstrated by in vivo studies in mice. In particular, these NPs were obtained starting from two polyaspartamide-based copolymers which were synthesized by chemical reaction of α,β-poly(N-2-hydroxyethyl)- dl -aspartamide (PHEA) and its pegylated derivative (PHEA-PEG2000) with poly(lactic acid) (PLA). To obtain nanosized particles, the high pressure homogenization (HPH)—solvent evaporation method was followed by using an organic phase containing both PHEA-PLA and PHEA-PEG2000-PLA (at a weight ratio equal to 1:…
FRESH AND DEHYDRATED SULLA FORAGE IN DAIRY EWES FEEDING: EFFECTS ON FEED UTILIZATION, OXIDATIVE STATUS AND PROPERTIES OF MILK AND CHEESE
2022
Polysarcosine-Based Lipids: From Lipopolypeptoid Micelles to Stealth-Like Lipids in Langmuir Blodgett Monolayers.
2016
Amphiphiles and, in particular, PEGylated lipids or alkyl ethers represent an important class of non-ionic surfactants and have become key ingredients for long-circulating (“stealth”) liposomes. While poly-(ethylene glycol) (PEG) can be considered the gold standard for stealth-like materials, it is known to be neither a bio-based nor biodegradable material. In contrast to PEG, polysarcosine (PSar) is based on the endogenous amino acid sarcosine (N-methylated glycine), but has also demonstrated stealth-like properties in vitro, as well as in vivo. In this respect, we report on the synthesis and characterization of polysarcosine based lipids with C14 and C18 hydrocarbon chains and their end g…
Preparation of tungstophosphoric acid/cerium-doped NH2-UiO-66 Z-scheme photocatalyst: a new candidate for green photo-oxidation of dibenzothiophene a…
2021
International audience; The goal of this study was to introduce an effective visible-light induced photocatalytic system with a good ability for photocatalytic oxidative desulfurization (PODS) and denitrogenation (PODN) using molecular oxygen (O2) as an oxidant. In this regard, tungestophosphoric acid (PW12) was supported onto cerium-doped NH2-UiO-66 (PW12/Ce-NUiO-66) and employed for the photo-oxidation of dibenzothiophene (DBT) and quinoline (Qu). Herein, using cerium (Ce) as a “mediator” facilitated the separation of charge carriers, while NH2-UiO-66 remarkably enhanced the surface area with plentiful adsorption sites and shifted the adsorption edge of PW12to the visible region. The sum …
Los procesos inferenciales en lectores con síndrome de Down
2013
The aim of this work is to know if the source of the difficulty in making inferences, readers with Down syndrome, is in access to prior knowledge or constructing ideas from purely textual knowledge (based on Saldaña and Frith, 2002 for autism). Involved a sample of 20 students with Down syndrome and mild mental retardation (mean IQ = 60) and a control group of 20 children without cognitive deficits. They were matched as to their extent read metal age via Prueba de Evaluación del Retraso Lector (average 8 years). We created two experimental situations: a) subjects had to generate inferences based on physical knowledge, b) social inferences about knowledge. The ability to check and reaction t…
Privacidad en redes sociales. Un estudio con jóvenes de 12 a 16 años
2016
Desde hace apenas unos años, las redes sociales virtuales se han convertido en una de las herramientas tecnológicas más impactantes a nivel social, las cuales nos permiten un sinfín de posibilidades, desde comunicarnos hasta conocer a otras personas, compartir cualquier tipo de información y entretenernos. No obstante, a pesar de la gran cantidad de ventajas que pueden aportarnos, no están exentas de posibles peligros que principalmente afectan a la privacidad y seguridad de los internautas, en especial de los usuarios más jóvenes. Es por ello por lo que nace el presente estudio, el cual pretende conocer, identificar y analizar diferentes aspectos vinculados con la seguridad y privacidad en…
Control y privacidad en el ciberespacio. Uso de las cookies por parte de los principales medios digitales españoles.
2015
En marzo de 2012 la legislación española incorporó la directiva comunitaria sobre privacidad electrónica. Desde ese momento, todas las páginas web españolas que recopilan datos a través de cookies y tecnologías similares (siempre que estos archivos no sean estrictamente necesarios para el funcionamiento de la página), tienen la obligación de informar claramente sobre el tipo y la finalidad de los datos recolectados, así como de obtener el consentimiento de los usuarios a destinar sus datos a tal efecto. En mayo de 2013, la AEPD publicó, junto con representantes de la industria mediática y publicitaria, la "Guía sobre el uso de las cookies", dirigida a editores web y que tiene como objetivo …
El programa Erasmus y el desarrollo de capacidades : un análisis multidimensional
2014
Presentamos un proyecto de investigación cuyo objeto de estudio es la experiencia Erasmus, teniendo como protagonistas a aquellas personas que participan en el mismo, las que lo gestionan y promueven y a aquellos que se interesan por los beneficios de dicha iniciativa. En líneas generales, nos mueve el propósito de obtener información sobre las aportaciones del programa respecto al desarrollo humano a partir del enfoque de capacidades de Amartya Sen y Marta Nussbaum. Nuestra finalidad última se concreta, por tanto, en la siguiente cuestión: ¿Cómo contribuye el programa Erasmus a dicho desarrollo? Esto nos ha llevado a establecer tres grandes procesos. En primer lugar, hacemos una revisión d…
Prostaglandin E2 and prostaglandin F2 alpha as endometrial receptivity biomarkers in successful embryo implantation
2014
Failure in the adhesion of the human blastocyst to the endometrium has been described as an important cause of infertility. Establishing the period of the so-called window of implantation and understanding the molecular mechanisms associated with embryo implantation has clinical and scientific implications. While over the last decades histological evaluation has been used to determine the phase of the menstrual cycle of the endometrium, the poor information obtained has made the case of using new technologies to identify specific markers, understand and characterize the receptive stage. This doctoral thesis investigates the existence, function and clinical impact of two specific lipids, the…