Search results for "ACL"
showing 10 items of 906 documents
Is the Kidscreen-27 a valid measure of health-related quality of life in 10-year-old Norwegian children?
2015
The aim of this study was to investigate the reliability and validity of the Norwegian Kidscreen-27 questionnaire, a measure of generic health-related quality of life, in 10 year-old children. The Kidscreen-27 consists of five domains and was validated in a sample of 56 school children (29 boys). The children completed the questionnaire at three different time points during two consecutive school days. For convergent validity, the study was powered to detect a statistically significant correlation coefficient of 0.4. Cronbach's alpha values ranged from 0.73 to 0.83. Floor effects were all zero and ceiling effects ranged from 1.7% to 23.7%. Intraclass correlation values over time ranged from…
Pressure of the hot gas in simulations of galaxy clusters
2016
We analyze the radial pressure profiles, the ICM clumping factor and the Sunyaev-Zel'dovich (SZ) scaling relations of a sample of simulated galaxy clusters and groups identified in a set of hydrodynamical simulations based on an updated version of the TreePM-SPH GADGET-3 code. Three different sets of simulations are performed: the first assumes non-radiative physics, the others include, among other processes, AGN and/or stellar feedback. Our results are analyzed as a function of redshift, ICM physics, cluster mass and cluster cool-coreness or dynamical state. In general, the mean pressure profiles obtained for our sample of groups and clusters show a good agreement with X-ray and SZ observa…
ON the NATURE of HYDROSTATIC EQUILIBRIUM in GALAXY CLUSTERS
2016
In this paper we investigate the level of hydrostatic equilibrium (HE) in the intra-cluster medium of simulated galaxy clusters, extracted from state-of-the-art cosmological hydrodynamical simulations performed with the Smoothed-Particle-Hydrodynamic code GADGET-3. These simulations include several physical processes, among which stellar and AGN feedback, and have been performed with an improved version of the code that allows for a better description of hydrodynamical instabilities and gas mixing processes. Evaluating the radial balance between the gravitational and hydrodynamical forces, via the gas accelerations generated, we effectively examine the level of HE in every object of the sam…
Universal thermodynamic properties of the intracluster medium over two decades in radius in the X-COP sample
2018
The hot plasma in galaxy clusters is expected to be heated to high temperatures through shocks and adiabatic compression. The thermodynamical properties of the gas encode information on the processes leading to the thermalization of the gas in the cluster's potential well as well as non-gravitational processes such as gas cooling, AGN feedback and kinetic energy. In this work we present the radial profiles of the thermodynamic properties of the intracluster medium (ICM) out to the virial radius for a sample of 12 galaxy clusters selected from the Planck all-sky survey. We determine the universal profiles of gas density, temperature, pressure, and entropy over more than two decades in radius…
Cross-Cultural Adaptation, Translation, and Validation of the Spanish Foot and Ankle Outcome Score Questionnaire
2020
The Spanish Foot and Ankle Outcome Score questionnaire (FAOS‐S) may be considered a health evaluation tool with 42 questions for assessing foot health disorders. To date, FAOS has been validated in different languages, but a Spanish version was lacking. Consequently, the purpose of this study was to translate and validate the Spanish version of the FAOS (FAOS es). A suitable method was developed for the translation protocol and cross‐cultural validation from Swedish to Spanish. Regarding the total marks from each domain, agreement degrees and confidence were analysed using the Cronbach's α and intraclass correlation coefficient, respectively. In addition, the mean ± SD differences between p…
Repeatability and reliability of the diabetic foot self-care questionnaire in Arabic patients: A transcultural adaptation.
2022
Abstract Purpose The diabetic foot self-care questionnaire is considered a self-care evaluation tool with 16 questions for assessing diabetic foot health disorders. To date, the DFSQ has been validated in different languages, but an Arabic version was lacking. Consequently, the purpose of this study was to translate and validate the Arabic version of the DFSQ (DFSQ-AR). Method A suitable method was developed for the translation protocol and cross-cultural validation from Spanish to Arabic. Regarding the total marks from each sub-scale, agreement degrees and confidence were analyzed using Cronbach's α and intraclass correlation coefficient (ICC), respectively. In addition, the mean ± standar…
Framing Migrant Memories: Lampedusa's Fragmented Archives
2022
The small island of Lampedusa, a key destination of the Central Mediterranean Route connecting Africa to Italy, offers a special observatory on the contemporary trans-Mediterranean odyssey of migrants, although often transformed into a “border spectacle.” Upon landing, migrants are stripped of their belongings, as these are impounded by the authorities. Such an act of dispossession is intended to deprive them of their histories, family ties and cultural identity. Photographer Mario Badagliacca has portrayed a selection of these lost and retrieved items in his work Fragments (2013). Each object reveals expectations, fears, desires, endurance, but cannot tell a full story. They are fragments …
When Ethics and Aesthetics Are One and the Same: A Wittgensteinian Perspective on Natural Value
2015
Many environmental philosophers have held naturalness to be a primary source of nature’s value. Seen this way, the nature that is most valuable is wild nature, and ‘wild’ is that which is unmodiled by human activity. However, accounts of our attributions of value to the wild often have an aura of elusiveness to them, as if what really matters about nature being wild could not ultimately be captured by words. In an attempt to account for what really matters, I relate our fascination with wild nature to a famous Wittgensteinian quote—‘Ethics and Aesthetics are one and the same’ (Tractatus 2006a: 28, §6.421)—and inspect the ways in which important dimensions of our attributions of value to wil…
Type designation of the name of the conifer Araâr-tree Tetraclinis articulata (Cupressaceae)
2018
The typification of the name Tetraclinis articulata (Cupressaceae) is discussed. Previous type designation is considered ineffective. Original material conserved in the herbarium of the Natural History Museum of Denmark at C is designated as the lectotype.
Low doses of paclitaxel potently induce apoptosis in human retinoblastoma Y79 cells by up-regulating E2F1.
2008
Paclitaxel (PTX) is an anticancer drug currently in phase II clinical trials. This study shows for the first time that low doses of PTX (5 nM) potently induce apoptosis in human retinoblastoma Y79 cells. The effect of PTX is accompanied by a potent induction of E2F1 which appears to play a critical role in the effects induced by PTX. PTX induced a dose- and time-dependent effect, with G2/M arrest, cyclines A, E and B1 accumulation and a marked modification in the status of Cdc2-cyclin B1 complex, the major player of the G2/M checkpoint. Apoptosis followed G2/M arrest. An early and prolonged increase in p53 expression with its stabilization by phosphorylation and acetylation and its nuclear …