Search results for "ADAM"
showing 10 items of 372 documents
Electrostatically operated micromirrors for a Hadamard transform spectrometer
2002
The paper presents the development of a linear micromirror array which can be used as a switchable entrance mask for a double-array Hadamard transform spectrometer. In addition to the detector array the double-array spectrometer has a linear multi-slit array realised by independently switchable micromirrors at the entrance side. Two different switch positions of the electrostatically operated mirrors allow the reflection of light into or away from the spectrometer. With this arrangement (mirror array, concave grating and array detector) and the use of the Hadamard transform principle it is possible to increase the signal-to-noise ratio and the resolution of the system compared to convention…
The metalloproteinase-disintegrin ADAM10 is exclusively expressed by type I muscle fibers.
2008
ADAM10 (Kuzbanian) is a member of a recently discovered family of membrane-anchored metalloproteinases with a complex and conserved domain structure. In part, these metalloproteinases have been implicated in muscle formation. Herein the expression pattern of ADAM10 in human skeletal muscle was studied. ADAM10 was found to be present in human myoblasts and to be exclusively expressed in type I fibers, suggesting that it may be critical in muscle fiber differentiation.
Pour penser un dialogue entre l'herméneutique gadamérienne et la déconstruction derridienne
2019
Although Gadamer's philosophical hermeneutics and Derrida's deconstruction are two important school of thoughts on the theory of interpretation, there are little connections between them. Especially after the unsuccessful meeting between Derrida and Gadamer at Paris in 1981, there were practically no collaborations between the two camps. As a result, the existing literatures comparing these two school of thoughts suffer two general problems. First, most focus only on their 1981 debate at Paris. Secondly, even for the commentators who take a wider approach, the investigation is often one-sided, simplifying too much the opposing side of the debate.The present project takes into consideration …
Platona darba “Faidons” lasījumi: Gregorija Vlastosa, Hansa-Georga Gadamera un Aleksandra Nehamasa pieejas
2018
Šajā bakalaura darbā pievēršos trīs nozīmīgu 20. gadsimta Platona lasītāju - Gregorija Vlastosa, Hansa-Georga Gadamera un Aleksandra Nehamasa - tekstiem, kas veltīti Platona darbam Faidons. Darba pirmajās trīs nodaļās aplūkoju katra autora trīs Faidonu komentējošus tekstus, pieņēmumus, secinājumus un pieejas, kas tajos uzrādāmas, kā arī katra autora saistību ar Platona lasījumu tradīcijām. Ceturtajā nodaļā salīdzinu kopīgo un atšķirīgo Vlastosa, Gadamera un Nehamasa uzskatos un metodēs, bet darba noslēgumā sniedzu visu trīs autoru pieeju izvērtējumu. Darba ietvaros aplūkoju Gregorija Vlastosa darbus “Iemesli un cēloņi Faidonā”, “Piezīme par “pāviliskajām predikācijām” Platona darbos” un “Re…
La fortuna della «Cronica» di Salimbene de Adam fra Trecento e Quattrocento
2018
Studio della fortuna della «Cronica» di Salimbene de Adam fra Tre e Quattrocento, in particolare in Dante, Boccaccio e Poggio Bracciolini.
Valdas Adamkus un Vaira Vīķe –Freiberga: rietumu politiskā līderība postkomunistiskā Lietuvā un Latvijā
2016
Vaira Vīķe-Freiberga un Valdas Adamkus ir divi izcili politiskas līderības paraugi Latvijā un Lietuvā. Viņu politiskie uzskati nobrieda trimdā Rietumos, bet prezidentiem bija jācenšas tos uzskatus pielietot postkomunistiskā Latvijas un Lietuvas realitātē. Adamkus mēģināja transformēt politisko kultūru un partiju sistēmu; bet kad viņam tas neizdevās viņš koncentrējās uz ārpolitiskiem mērķiem un mēģināja atbalstīt reformas citas postkomunistiskajās valstīs, arī popularizēt pilsoniskās sabiedrības idejas savā valstī. Vīķe-Freiberga apņēmās pacelt Latvijas pašpārliecību mājās un starptautisko organizāciju acīs. Šis maģistra darbs ir mēģinājums salīdzināt prezidentu politiskās stratēģijas Rietum…
Diagonal space time hadamard codes with erasure decoding algorithm
2005
A major challenge in the area of space time (ST) codes is to find codes suitable for efficient decoding, thus overcoming the problem of many existing ST code designs which require maximum-likelihood (ML) decoding. A solution could be to apply single-input single-output (SISO) channel codes and theory over temporal channel fading to the multi-input single-output (MISO) code construction and classical suboptimum decoding methods. For these purposes, an ST code construction which allows the use of efficient decoding algorithms is described. We propose a concatenated code, where the inner code is the diagonal ST Hadamard (D-STH) code with Paley constructions and the outer code is an algebraic b…
Influence of ADAM10 on prion protein processing and scrapie infectiosity in vivo.
2009
Abstract Both the cellular prion protein (PrPc) and the amyloid precursor protein (APP) are physiologically subjected to complex proteolytic processing events. While for APP the proteinases involved – alpha-, beta- and gamma-secretase – have been identified in vitro and in vivo, the cleavage of PrPc by now has been linked only to the shedding activity of the metalloproteinase ADAM10 and/or ADAM17 in cell culture. Here we show that neuronal overexpression of the alpha-secretase ADAM10 in mice reduces all PrPc species detected in the brain instead of leading to enhanced amounts of specific cleavage products of PrPc. Additionally, the incubation time of mice after scrapie infection is signific…
Catalogue of Adam Smith's Library
1894
"Edited with an introduction by James Bonar"
A cellular metalloproteinase activates Vibrio cholerae pro-cytolysin.
2004
Many strains of Vibrio cholerae produce a cytolysin (VCC) that forms oligomeric transmembrane pores in animal cells. The molecule is secreted as a procytolysin (pro-VCC) of 79 kDa that must be cleaved at the N terminus to generate the active 65-kDa toxin. Processing can occur in solution, and previous studies have described the action of mature VCC thus generated. However, little is known about the properties of pro-VCC itself. In this study, it is shown that pro-VCC exist as a monomer in solution and binds as a monomer to eukaryotic cells. Bound pro-VCC can then be activated either by exogenous, extracellular, or by endogenous, cell-bound proteases. In both cases, cleavage generates the 65…