Search results for "ADE"

showing 10 items of 15269 documents

Zakres zastosowania prawa cywilnego w ramach instytucji podmiotu zobowiązanego do zwrotu korzyści majątkowej (art. 91a k.p.k.) - wybrane zagadniania

2023

Instytucja podmiotu zobowiązanego do zwrotu korzyści majątkowej poprzednio była uregulowana w art. 52 Kodeksu karnego1 oraz art. 416 Kodeksu postępowania karnego2. Przepisy te zostały uchylone, jednak po około dwóch latach ustawodawca powrócił do wspomnianego rozwiązania w art. 91a i art. 415a k.p.k. W porównaniu do wcześniejszej regulacji zmodyfikowano warunki zobowiązania, uprawnienia i obowiązki podmiotu oraz procesowe aspekty orzekania o jego odpowiedzialności. Szczegółowo ustawodawca zredagował zakres zastosowania prawa cywilnego w ramach instytucji podmiotu zobowiązanego do zwrotu korzyści majątkowej. Celem niniejszego artykułu jest wskazanie, w jakim zakresie prawo cywilne znajdzie z…

return of property benefitszwrot nienależnego świadczeniareturn of undue benefitszwrot korzyści majątkowejpodmiot zobowiązany do zwrotu korzyścientity obligated to return the benefitsbenefits from commission of a crimeforfeiture of property benefitsprzepadek korzyści majątkowejkorzyść z popełnienia przestępstwaDyskurs Prawniczy i Administracyjny
researchProduct

Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins Rho involved in assembly of actin s…

1994

Cytotoxic necrotizing factor type 2 (CNF2) produced by Escherichia coli strains isolated from intestinal and extraintestinal infections is a dermonecrotic toxin of 110 kDa. We cloned the CNF2 gene from a large plasmid carried by an Escherichia coli strain isolated from a lamb with septicemia. Hydropathy analysis of the deduced amino acid sequence revealed a largely hydrophilic protein with two potential hydrophobic transmembrane domains. The N-terminal half of CNF2 showed striking homology (27% identity and 80% conserved residues) to the N-terminal portion of Pasteurella multocida toxin. Methylamine protection experiments and immunofluorescence studies suggested that CNF2 enters the cytosol…

rho GTP-Binding ProteinsBacterial ToxinsMolecular Sequence DataRestriction Mapping[SDV.BC]Life Sciences [q-bio]/Cellular BiologyBiologyIn Vitro TechniquesSEQUENCE GENIQUEmedicine.disease_causeCell LineGTP-binding protein regulatorsGTP-Binding ProteinsmedicineEscherichia coliHumansCloning MolecularCytoskeletonEscherichia coliPeptide sequence[SDV.BC] Life Sciences [q-bio]/Cellular BiologyActinAdenosine Diphosphate RiboseMultidisciplinaryBase SequenceSequence Homology Amino AcidCytotoxinsBinding proteinEscherichia coli ProteinsMolecular biologyActinsCytosolTransmembrane domainActin CytoskeletonBiochemistryGenes BacterialFACTEUR CYTOTOXIQUE NECROSANTSequence AlignmentResearch Article
researchProduct

Rho GTPases are over-expressed in human tumors.

1999

Small GTPases of the Rho family are involved in the regulation of a variety of cellular processes, such as the organization of the microfilamental network, cell-cell contact and malignant transformation. To address the question of whether Rho proteins are involved in carcinogenesis in man, we compared their expression in tumors from colon, breast and lung with that of the corresponding normal tissue originating from the same patient. As shown by Rho-specific 32P-ADP-ribosylation, as well as Western-blot analysis, the amount of RhoA protein was largely increased in all 3 types of tumors tested. The most dramatic differences in the expression of Rho GTPases were observed in breast tissue. All…

rho GTP-Binding ProteinsCancer ResearchPathologymedicine.medical_specialtyRHOALung NeoplasmsColonBreast NeoplasmsCell Cycle ProteinsGTPaseCDC42medicine.disease_causeMalignant transformationGTP PhosphohydrolasesGTP-Binding ProteinsmedicineHumansrho-Specific Guanine Nucleotide Dissociation InhibitorsBreastcdc42 GTP-Binding ProteinrhoB GTP-Binding ProteinLungGuanine Nucleotide Dissociation InhibitorsMitogen-Activated Protein Kinase 1Adenosine Diphosphate RibosebiologyCancerMembrane Proteinsmedicine.diseaseImmunohistochemistryrac GTP-Binding ProteinsOncologyrhoC GTP-Binding ProteinCalcium-Calmodulin-Dependent Protein KinasesColonic Neoplasmsbiology.proteinCancer researchImmunohistochemistryCarcinogenesisrhoA GTP-Binding ProteinRhoC GTP-Binding ProteinInternational journal of cancer
researchProduct

Metabotropic glutamate receptors activate phospholipase D in astrocytes through a protein kinase C-dependent and Rho-independent pathway.

2003

Metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors that mediate phospholipase D (PLD) activation in brain, but the mechanism underlying this response remains unclear. Here we used primary cultures of astrocytes as a cell model to explore the mechanism that links mGluRs to PLD. Glutamate activated both phospholipase C (PLC) and PLD with equal potency and this effect was mimicked by L-cysteinesulfinic acid, a putative neurotransmitter previously shown to activate mGluRs coupled to PLD, but not PLC, in adult brain. PLD activation by glutamate was dependent on Ca(2+) mobilization and fully blocked by both protein kinase C (PKC) inhibitors and PKC down-regulation, suggesti…

rho GTP-Binding ProteinsIndolesBacterial ToxinsGlutamic AcidBiologyReceptors Metabotropic GlutamateSulfenic AcidsMaleimidesRats Sprague-DawleyCellular and Molecular NeuroscienceBacterial ProteinsStress FibersmedicinePhospholipase DAnimalsCysteineEgtazic AcidProtein kinase CCells CulturedProtein Kinase CChelating AgentsPharmacologyProtein Synthesis InhibitorsBrefeldin APhospholipase CDose-Response Relationship DrugEndothelin-1Phospholipase DADP-Ribosylation FactorsMetabotropic glutamate receptor 6Glutamate receptorDNAMolecular biologyRatsenzymes and coenzymes (carbohydrates)medicine.anatomical_structureMetabotropic receptorMetabotropic glutamate receptorAstrocytesType C PhospholipasesTetradecanoylphorbol Acetatelipids (amino acids peptides and proteins)AstrocyteNeuropharmacology
researchProduct

Cypriana Norwida słowo i druk

2009

rhytmic foothalf anti-cadencehexameterintonemecaesurapauserhythmstropheintonationrecitationrhymemusicsongsyllableprogredienceclausephonetic instrumentationphraserecitation workaccentdeclamationsilencepoemreciter's workcadencerhapsodyanti-cadencea living wordpoetryStylistyka [Polish Academy of Sciences. Committee of Linguistics - Warsaw, Polish Academy of Sciences. Institute of Polish Language - Cracow, Pedagogical University - Opole. Institute of Polish Philology]
researchProduct

Rassegna Sezioni Unite- Scenari

2012

La rassegna delle sezioni unite rigurada decisioni molto interessanti sui temi: dell' interpretazione conforme del giudice nazionale, della presunzione di adeguatezza della custodia cautelare, del mandato di arresto europeo, della captazione di corrispondenza del detenuto , del ricorso straordinario per errore di fatto, dell'incompetenza con riguardo al giudizio abbreviato.

ricorso straordinario per errore di fattopresunzione di adeguatezza della custodia cautelaregiudizio abbreviato.Interpretazione conformemandato di arresto europeosequestro di corrispondenza del detenuto
researchProduct

Detección precoz de riesgo social en paciente hospitalizado: validación de cuestionario y relación con Patrones Funcionales y calidad de vida

2015

INTRODUCCIÓN El envejecimiento progresivo de la población está provocando una serie de cambios en la estructura sociodemográfica de la población. Este envejecimiento conlleva una serie de modificaciones en el uso y en la necesidad de recursos, pues en muchos casos la vejez lleva asociada en muchas ocasiones enfermedades crónicas y alteraciones en la capacidad funcional. Es en esta situación cuando las personas mayores sufren una mayor vulnerabilidad a factores de riesgo social. Además, esta vulnerabilidad está asociada con la percepción de calidad de vida y va a determinar su relación con el entorno. En el medio hospitalario se hace indispensable un cambio en la intervención con los mayores…

riesgo socialcalidad de vidavaloración de enfermeríapaciente mayor:CIENCIAS MÉDICAS ::Otras especialidades médicas [UNESCO]UNESCO::CIENCIAS MÉDICAS ::Otras especialidades médicas
researchProduct

Olive oil intake and risk of cardiovascular disease and mortality in the PREDIMED Study

2014

[Background] It is unknown whether individuals at high cardiovascular risk sustain a benefit in cardiovascular disease from increased olive oil consumption. The aim was to assess the association between total olive oil intake, its varieties (extra virgin and common olive oil) and the risk of cardiovascular disease and mortality in a Mediterranean population at high cardiovascular risk.

riesgoMediterranean diethumanosMyocardial InfarctionCardiovascularlaw.inventionCohort StudiesRandomized controlled triallawRisk FactorsNeoplasmsestudios prospectivosNutsMyocardial infarctionProspective StudiesProspective cohort studyestudios de cohortesmediana edadMedicine(all)neoplasiaseducation.field_of_studyancianodietaGeneral MedicineMiddle AgedStrokeOli d'olivaCardiovascular diseasesCardiovascular Diseasesaceites de plantasCohort studyRiskPREDIMEDmedicine.medical_specialtyPopulationenfermedades cardiovascularesNational Death IndexMediterranean dietEnvironmental healthmedicineMortalitatHumansPlant Oilsfactores de riesgoaccidente cerebrovascularMortalityeducationinfarto de miocardioAgedMediterranean DietProportional hazards modelbusiness.industryMalalties cardiovascularsmedicine.diseaseSurgeryDietnuecesbusinessOlive oil
researchProduct

Il limite della buona fede nell'applicazione della clausola "simul stabunt simul cadent"

2013

La pronuncia in commento s’inserisce nel recente orientamento del Tribunale di Milano secondo il quale l’utilizzo della clausola ‘‘simul stabunt simul cadent’’ al solo fine di estromettere uno o piu` amministratori dalla gestione della societa` costituisce una violazione della buona fede nei rapporti endosocietari. La sentenza offre un’ulteriore occasione per riflettere sui limiti di utilizzo della suddetta clausola statutaria, consentendo all’interprete di prospettare in quest’ambito ulteriori sviluppi applicativi della clausola generale di buona fede e dell’abuso del diritto

risarcimento dannodimissioniclausola di buona fedeamministratoriSocieta` per azioniclausola "simul stabunt simul cadent"
researchProduct

Il danno da risoluzione

2017

Il saggio affronta la controversa questione dell'identificazione del danno da risoluzione e, di conseguenza, della funzione complessiva dell'istituto della risoluzione. Il panorama dottrinale e giurisprudenziale è diviso tra fautori della commisurazione del danno da risoluzione ora all'interesse positivo ora all'interesse negativo. L'autore propone una lettura nella diversa prospettiva della natura consequenziale del danno , così da superare l'impostazione tradizionale al tema del pregiudizio in sede di risoluzione, che così tanta incertezza ha generato. Il saggio si chiede esaminando il tema assai complesso del rapporto tra i rimedi della risoluzione e del risarcimento sostitutivo della pr…

risoluzione danno interesse positivo interesse negativo adempimento in natura risarcimento sostitutivoSettore IUS/01 - Diritto Privato
researchProduct