Search results for "ADE"

The sociology of professions and the study of the academic profession

2018

Studies on metazoan parasites of two marine fish species of interest for aquaculture: Seriola dumerili and Sparus aurata

2013

0.1. Introducción general La acuicultura ha experimentado un importante aumento durante los últimos 50 años, resultado del incremento global de población y la creciente demanda de proteínas de alta calidad. En los últimos 40 años, la proporción de reservas pesqueras moderadamente explotadas ha descendido progresivamente hasta estabilizarse en el 15% y en la actualidad, la mayoría de los stocks pesqueros están sobreexplotados y (FAO, 2010). Más de la mitad de los productos acuáticos provienen de granjas, siendo los peces de agua dulce los animales más cultivados seguidos por los moluscos, los crustáceos, los peces diádromos y los peces marinos (FAO, 2010). España es el país con mayor producc…

Collaborative Design Rational and Social Creativity in Cultures of Participation

2011

The rise in social computing has facilitated a shift from consumer cultures, focused on producing finished media to be consumed passively, to cultures of participation, where people can access the means to participate actively in personally meaningful problems. These developments represent unique and fundamental opportunities and challenges for rethinking and reinventing design rationale and creativity, as people acclimate to taking part in computer-mediated conversations of issues and their solutions. Grounded in our long-term research exploring these topics, this paper articulates arguments, describes and discusses conceptual frameworks and system developments (in the context of three cas…

Combining spatial prioritization and expert knowledge facilitates effectiveness of large-scale mire protection process in Finland

2020

Conservation resource allocation involves a complex set of considerations including species, habitats, connectivity, local to global biodiversity objectives, alternative protection and restoration actions, while requiring cost-efficiency and effective implementation. We present a national scale spatial conservation prioritization analysis for complementing the network of protected mires in Finland. We show how spatial prioritization coupled with regional targets and expert knowledge can facilitate structured decision-making. In our application, discussion between experts was structured around the prioritization model enabling integration of quantitative analysis with expert knowledge. The u…

Temperature measurement in gas mixtures by femtosecond Raman-induced polarization spectroscopy

2003

European Conference on Nonlinear Optical Spectroscopy (ECONOS) MAR 30-APR 01, 2003 BESANCON, FRANCE; The potential of femtosecond Raman-induced polarization spectroscopy (RIPS) for the simultaneous determination of temperature and concentrations was investigated. These measurements were related to the rotational time response of the molecular gas mixture, which was measured as a function of the pump-probe time delay. The change of the polarizability anisotropy with respect to the vibrational levels was taken into account. The results of temperature measurements in pure CO2 showed good agreement with the values obtained by a thermocouple. The RIPS technique was also applied to a CO2-N2 gas m…

The NUMEN project @ LNS: Status and perspectives

2017

The NUMEN project aims at accessing experimentally driven information on Nuclear Matrix Elements (NME) involved in the half-life of the neutrinoless double beta decay (0νββ), by high-accuracy measurements of Heavy Ion (HI) induced Double Charge Exchange (DCE) reaction cross sections. In particular, the (18O,18Ne) and (20Ne,20O) reactions are used as tools for β+β+ and β−β− decays, respectively. In the experiments, performed at INFN - Laboratory Nazionali del Sud (LNS) in Catania, the beams are accelerated by the Superconducting Cyclotron (CS) and the reaction ejectiles are detected the MAGNEX magnetic spectrometer. The measured cross sections are challengingly low (a few nb), being the tota…

Impact of Structural, Photochemical and Instrumental Effects on Leaf and Canopy Reflectance Variability in the 500–600 nm Range

2021

Current rapid technological improvement in optical radiometric instrumentation provides an opportunity to develop innovative measurements protocols where the remote quantification of the plant physiological status can be determined with higher accuracy. In this study, the leaf and canopy reflectance variability in the PRI spectral region (i.e., 500–600 nm) is quantified using different laboratory protocols that consider both instrumental and experimental set-up aspects, as well as canopy structural effects and vegetation photoprotection dynamics. First, we studied how an incorrect characterization of the at-target incoming radiance translated into an erroneous vegetation reflectance spectru…

Integrating vehicle specific power methodology and microsimulation in estimating emissions on urban roundabouts

2021

In this study pollutant emissions were estimated from VSP modal emission rates and the distribution of time spent in each VSP mode obtained from the speed profiles both gathered in the field and simulated in AIMSUN at a sample of urban roundabouts. The versatility of the micro-simulation model for a calibration aimed at improving accuracy of emissions estimates was tested in order to ensure that second-by-second trajectories experienced in the field by a test vehicle through the sampled roundabouts properly reflected the simulated speed profiles. The first results which the thesis will refer, confirmed the feasibility of the smart approach that integrates the use of field-observed and simul…

A microsimulation calibration methodology based on speed-density relationships for freeways

2014

This paper describes the calibration methodology based on speed-density relationships in the microsimulation calibration process, stated that they represent the traffic flow phenomenon in a wide range of operational conditions and well summarize all the information that may be collected on field (or following a run of the microsimulation model) on two of the three key variables of traffic flow. The matching of speed-density relationships from field and simulation was evaluated using statistical analysis as technique of pattern recognition. A test freeway segment under uncongested traffic conditions was selected as case study; based on traffic data observed at A22 Brenner Freeway, Italy, sta…

DESIGN OF SF3B1 SUBUNIT MODULATORS OF THE SF3B SPLICEOSOME COMPLEX

2022

The subject of this dissertation is the search for new therapeutic strategies for pancreatic cancer and aims to implement a Drug Discovery process for the rational design and synthesis of molecules active in the modulation of pathways related to the regulation of pre-mRNA splicing process. This research project is the result of a joint PhD between the University of Palermo, Italy, and the Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands. It integrates complementary skills in pharmaceutical chemistry and translational cancer research with a special focus on the rational design of new anticancer compounds potentially active on SF3B1 (Splicing Factor 3B …