Search results for "ADE"
showing 10 items of 15269 documents
Timing the information system upgrade
2010
A system upgrade requires careful planning as its implications to organizational systems might be enormous. Although in IS literature the requirements and process of systems upgrade have been discussed, the timing when to upgrade and what factors guide it has been of lesser interest. Consequently, in this paper we focus on information systems upgrading and its timing from the perspective of the user organization. Upgrading is enabled by the availability of a new software version. When to upgrade, meanwhile, is determined by the business interests of the customer organization, business calendar, development projects, and the vendor. These factors were identified by interviewing 14 IT manager…
Tensor tympani muscle: strange chewing muscle
2007
This work seeks to alert medical and odontological staff to understanding and using interdisciplinary handling for detecting different pathologies’ common otic symptoms. It offers better tools for this shared symptomatology during therapy’s conservative phase. Tensor tympani muscle physiology and function in the middle ear have been veiled, even when their dysfunction and anatomical relationships may explain a group of confused otic symptoms during conventional clinical evaluation. Middle ear muscles share a common embryological and functional origin with chewing and facial muscles. This article emphasizes that these muscles share a functional neurological and anatomical dimension with the …
Marcadores clínicos y estudio de estilo de vida en el seguimiento de la enfermedad celíaca
2020
La enfermedad celíaca (EC) es un trastorno sistémico, crónico y de origen autoinmune que afecta a individuos genéticamente susceptibles. Se presenta con una gran variedad de signos, síntomas y enfermedades asociadas, incluso también puede cursar de manera asintomática, lo que hace difícil su diagnóstico. La EC se diagnostica con mayor frecuencia en las mujeres y a edades más tempranas que a los hombres. Debido a la gran hererogeneidad en la forma de presentación de la EC, se ha llevado a cabo una revisión sistemática, donde estudios recientes, muestran una variación del espectro clínico de la enfermedad en función de la edad. En niños pequeños predomina la forma clásica con síntomas como di…
Los efectos de las asimetrías de género en la salud de las mujeres
2003
This study analyses the effects on health of the asymmetry of power relations between the sexes and, specifically, how life conditions have a bearing on personal well-being. Subjective discomfort usually manifests itself by means of symptoms. Epidemiological studies show a higher physical and mental morbidity in women. A critica1 review of previous studies highlights the connections between symptoms and gender role and shows the existence of bias in the theoretical models and clinical practices. The implementation of health policies which take into account this bias - which consists in extrapolating the results obtained in exclusively male samples to the design of diagnostic methods, treatm…
Koģenerācijas staciju koksnes pelnu un bioogles īpašības un to izmantošanas iespējas lauksaimniecībā
2017
Biomasas koģenerācijas sistēmas ir labs risinājums videi draudzīgākas enerģijas (siltuma un elektrības) ražošanā, tomēr biomasas sadedzināšanas rezultātā rodas ievērojams daudzums pelnu un bioogle, kas pārsvarā tiek apglabāti poligonos kā atkritumi. Maģistra darba mērķis – analizēt biomasas koģenerācijas staciju koksnes vieglo pelnu un bioogles sastāvu, īpašības, tajā skaitā toksicitāti, ietekmi uz augu attīstību, kā arī izvērtēt izmantošanas iespējas lauksaimniecībā. Rezultāti liecina, ka vieglie pelni un bioogle, nepārsniedzot noteiktu koncentrācijas līmeni, veicina sēklu dīgtspēju, augu augšanu, biomasas pieaugumu un nodrošina labu sakņu attīstību. Tādējādi pelnus un bioogli ir iespējams…
Functional characterization of the human tRNA methyltransferases TRMT10A and TRMT10B
2020
Abstract The TRM10 family of methyltransferases is responsible for the N1-methylation of purines at position 9 of tRNAs in Archaea and Eukarya. The human genome encodes three TRM10-type enzymes, of which only the mitochondrial TRMT10C was previously characterized in detail, whereas the functional significance of the two presumably nuclear enzymes TRMT10A and TRMT10B remained unexplained. Here we show that TRMT10A is m1G9-specific and methylates a subset of nuclear-encoded tRNAs, whilst TRMT10B is the first m1A9-specific tRNA methyltransferase found in eukaryotes and is responsible for the modification of a single nuclear-encoded tRNA. Furthermore, we show that the lack of G9 methylation cau…
Dependency on un-captured GDP as a source of resilience beyond economic value in countries with advanced ICT infrastructure: Similarities and dispari…
2015
Abstract The majority of countries with advanced information and communication technology (ICT) infrastructure have been experiencing extended stagnation due to an “embedded” trap in ICT advancement. However, certain countries have been able to sustain a high level of ICT- driven global competitiveness. This suggests that in these contexts there is resilience beyond economic value. Finland and Singapore can be considered countries of resilience with respect to ICT-driven global competitiveness because of their continued GDP growth despite the recession. While both countries share significant similarities including institutional strength in ICT, they demonstrate noteworthy disparities in the…
Supporting Institutional Awareness and Academic Advising using Clustered Study Profiles
2017
The purpose of academic advising is to help students with developing educational plans that support their academic career and personal goals, and to provide information and guidance on studies. Planning and management of the students’ study path is the main joint activity in advising. Based on a study log of passed courses, we propose to use robust, prototype-based clustering to identify a set of actual study path profiles. Such profiles identify groups of students with similar progress of studies, whose analysis and interpretation can be used for better institutional awareness and to support evidence-based academic advising. A model of automated academic advising system utilizing the possi…
Identity Use and Misuse of Public Persona on Twitter
2016
Social media sites have appeared during the last 10 years and their use has exploded all over the world. Twitter is a microblogging service that has currently 320 million user profiles and over 100 million daily active users. Many celebrities and leading politicians have a verified profile on Twitter, including Justin Bieber, president Obama, and the Pope. In this paper we investigate the '‘hundreds of Putins and Obamas phenomenon’ on Twitter. We collected two data sets in 2015 containing 582 and 6477 profiles that are related to the G20 leaders’ profiles on Twitter. The number of namesakes varied from 5 to 1000 per leader. We analysed in detail various aspects of the Putin and Erdogan rela…
Vibrational Perturbations and Ligand–Layer Coupling in a Single Crystal of Au144(SC2H4Ph)60 Nanocluster
2015
We have determined vibrational signatures and optical gap of the Au144(PET)60 (PET: phenylethylthiol, SC2H4Ph) nanocluster solvated in deuterated dichloromethane (DCM-D2, CD2Cl2) and in a single crystal. For crystals, solid-state (13)C NMR and X-ray diffraction were also measured. A revised value of 2200 cm(-1) (0.27 eV) was obtained for the optical gap in both phases. The vibrational spectra of solvated AU144(PET)60 closely resembles that of neat PET, while the crystalline-state spectrum exhibits significant inhomogeneous spectral broadening, frequency shifts, intensity transfer between vibrational modes, and an increase in the overtone and combination transition intensities. Spectral broa…