Search results for "ADULT PATIENTS"

showing 10 items of 82 documents

Assessment of the aesthetic impact and quality of life of home dental bleaching in adult patients

2020

Background This study aimed to evaluate the impact of home bleaching with 10% carbamide peroxide on the quality of life and aesthetic perception of patients. Material and methods A total of 107 patients between 18 and 38 years of age with good oral and general health and at least one anterior tooth in color A2 or darker were selected. Patients who previously underwent any type of bleaching procedures were excluded. All patients received a home bleaching treatment with 10% carbamide peroxide. Before beginning the bleaching treatment, the selected patients responded a form with the Oral Health Impact Profile short form (OHIP-14) and Oral Aesthetic Subjective Impact Scale (OASIS) questionnaire…

Home bleachinggenetic structuresAdult patientsbusiness.industryResearchDentistry030206 dentistryOral healthAesthetic perceptionOperative Dentistry and Endodonticsstomatognathic diseases030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineDental aestheticsQuality of lifeStatistical significanceMedicineMaxillary central incisorsense organsbusinessGeneral DentistryUNESCO:CIENCIAS MÉDICASJournal of Clinical and Experimental Dentistry
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An overview of the role of T cells in controlling tuberculosis infection in a pediatric population

2015

The most significant immunological studies of tuberculosis (TB) infection have involved adult patients. Few studies about the immune repertoire have been conducted in children. The purpose of this paper is to focus on cellular immune response to Mycobacterium tuberculosis by reviewing our studies conducted on children with different forms of TB infection between 1998 and 2006. Although the gold standard of TB diagnosis remains isolation of TB bacillus that also allows estimation of pattern of resistance of M. tuberculosis, the study of immune response can be useful for the early diagnosis and therapeutic follow-up of pediatric TB.

Immune repertoireTB bacillusTuberculosisbiologyAdult patientsIsolation (health care)business.industrybiology.organism_classificationmedicine.diseaseMycobacterium tuberculosisInfectious DiseasesImmune systemPediatrics Perinatology and Child HealthImmunologymedicineImmune response tuberculosis childrenbusinessPediatric population
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Comparison of two different techniques of reperfusion in adult orthotopic liver transplantation

2006

: The aim of this study was to determine the impact of two reperfusion techniques on the peri-operative hemodynamic changes and early post-operative graft function of adult patients undergoing orthotopic liver transplantation. Material and methods: From June 2003 to May 2004, 50 consecutive liver transplants were performed and divided into two groups: group A, 25 patients, portal vein flush with 500 cm3 of Ringer's lactate without vena caval venting. Group B, 25 patients, vena caval venting with no portal vein flush. Donor and recipient characteristics were similar in both groups. Sixty-four different parameters were analyzed, and Pearson's χ2 test and t-test were used for statistical analy…

InferiorAdultMalemedicine.medical_specialtyOrthotopic liver transplantation; Post-reperfusion syndrome; Reperfusion technique; Adolescent; Adult; Aged; Aged 80 and over; Child; Female; Humans; Liver Transplantation; Male; Middle Aged; Portal Vein; Reperfusion; Tissue Donors; Vena Cava Inferior; TransplantationVena CavaAdolescentOrthotopic liver transplantationmedicine.medical_treatmentPortal veinHemodynamicsPost-reperfusion syndromeVena Cava InferiorLiver transplantationVena caval80 and overmedicineHumansStatistical analysisChildAgedAged 80 and overReperfusion techniqueTransplantationAdult patientsPortal Veinbusiness.industrySignificant differenceMiddle AgedSettore ING-IND/35 - Ingegneria Economico-GestionaleTissue DonorsLiver TransplantationSurgerySettore MED/18 - Chirurgia GeneraleReperfusioncardiovascular systemFemaleOrthotopic liver transplantationbusinessClinical Transplantation
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Etestw versus broth microdilution for ceftaroline MIC determination with Staphylococcus aureus: Results from PREMIUM, a European multicentre study

2017

Objectives: To compare the concordance of ceftaroline MIC values by reference broth microdilution (BMD) and Etest (bioMérieux, France) for MSSA and MRSA isolates obtained from PREMIUM (D372SL00001), a European multicentre study. Methods: Ceftaroline MICs were determined by reference BMD and by Etest for 1242 MSSA and MRSA isolates collected between February and May 2012 from adult patients with community-acquired pneumonia or complicated skin and soft tissue infections; tests were performed across six European laboratories. Selected isolates with ceftaroline resistance in broth (MIC >1 mg/L) were retested in three central laboratories to confirm their behaviour. Results: Overall concordance…

Male0301 basic medicineCephalosporinPharmacologiemedicine.disease_causeCommunity-acquired pneumoniaPneumonia StaphylococcalCommunity-Acquired InfectionPharmacology (medical)Pathologie maladies infectieusesAged 80 and overMicrobial Sensitivity TestBroth microdilutionCeftalorine; Staphylococcus aureus; PREMIUM STUDY GROUPCeftalorineMiddle AgedAnti-Bacterial AgentsCommunity-Acquired InfectionsEuropeInfectious DiseasesStaphylococcus aureusStaphylococcus aureuStaphylococcal Skin InfectionsFemaleHumanAdultMicrobiology (medical)medicine.medical_specialtyStaphylococcus aureusAdolescentmedicine.drug_classCephalosporin030106 microbiologyPREMIUM STUDY GROUPMicrobial Sensitivity TestsStaphylococcal Skin InfectionMicrobiologyYoung Adult03 medical and health sciencesInternal medicineAnti-Bacterial AgentmedicineHumansEtestAgedPharmacologyAdult patientsbusiness.industrybiochemical phenomena metabolism and nutritionmedicine.diseasebacterial infections and mycosesMethicillin-resistant Staphylococcus aureusCephalosporinsMethicillin Susceptible Staphylococcus Aureusbusiness
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International consensus on the diagnosis and management of pediatric patients with hereditary angioedema with C1 inhibitor deficiency

2016

BACKGROUND: The consensus documents published to date on hereditary angioedema with C1 inhibitor deficiency (C1-INH-HAE) have focused on adult patients. Many of the previous recommendations have not been adapted to pediatric patients. We intended to produce consensus recommendations for the diagnosis and management of pediatric patients with C1-INH-HAE.METHODS: During an expert panel meeting that took place during the 9th C1 Inhibitor Deficiency Workshop in Budapest, 2015 (www.haenet.hu), pediatric data were presented and discussed and a consensus was developed by voting.RESULTS: The symptoms of C1-INH-HAE often present in childhood. Differential diagnosis can be difficult as abdominal pain…

MaleAbdominal painPediatricsdiagnosisComorbidityDiseaseSeverity of Illness IndexEcallantide0302 clinical medicineRisk FactorsDiagnosisImmunology and Allergyheterocyclic compounds030212 general & internal medicineHereditary angioedemaPediatricHereditary Angioedema Types I and IIAge FactorsDisease ManagementCombined Modality TherapyImmunodeficienciesManagementHereditary angioedemaFemaleOriginal ArticleSymptom Assessmentmedicine.symptommanagementAlgorithmsmedicine.drugmedicine.medical_specialtyC1 inhibitor deficiencyImmunology03 medical and health sciencesMeta-Analysis as TopicmedicineHumansMucous MembraneAdult patientsbusiness.industryOriginal ArticlesC1 inhibitor deficiency; Diagnosis; Hereditary angioedema; Management; Pediatric; Immunology and Allergy; Immunologybacterial infections and mycosesmedicine.diseasehereditary angioedemarespiratory tract diseasesClinical trialpediatric030228 respiratory systemC1 inhibitor deficiencyDifferential diagnosisbusinessBiomarkers
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Differences among young adults, adults and elderly chronic myeloid leukemia patients

2014

Abstract BACKGROUND: The incidence of chronic myeloid leukemia (CML) increases with age, but it is unclear how the characteristics of the disease vary with age. In children, where CML is very rare, it presents with more aggressive features, including huge splenomegaly, higher cell count and higher blast cell percentage. PATIENTS AND METHODS: To investigate if after childhood the disease maintains or loses these characteristics of aggressiveness, we analyzed 2784 adult patients, at least 18 years old, registered by GIMEMA CML WP over a 40-year period. RESULTS: Young adults (YAs: 18-29 years old) significantly differed from adults (30-59 years old) and elderly patients (at least 60 years old)…

MalePediatricsHost responseBCR-ABL; Chronic myeloid leukemia; Prognosis; Tyrosine kinase inhibitors; Young adults; Adult; Age Factors; Aged; Aged 80 and over; Antineoplastic Agents; Female; Humans; Leukemia Myelogenous Chronic BCR-ABL Positive; Male; Middle Aged; Prospective Studies; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Spleen; Splenomegaly; Young Adult; Oncology; HematologyTyrosine kinase inhibitorDiseaseAntineoplastic AgentTyrosin kinase inhibitorProtein-Tyrosine Kinasehemic and lymphatic diseases80 and overAge FactorProspective StudiesYoung adultChronicBCR-ABLAged 80 and overLeukemiaIncidence (epidemiology)Chronic myeloid leukemiaAge FactorsMyeloid leukemiaHematologyMiddle AgedProtein-Tyrosine KinasesPrognosisLeukemiaOncologybcr-abl1FemaleBCR-ABL; chronic myeloid leukemia; prognosis; tyrosine kinase inhibitors; young adultsHumanAdultyoung adultsmedicine.medical_specialtyPrognosiProtein Kinase InhibitorAntineoplastic Agentschronic myeloid leukemia; bcr-abl1; Tyrosin kinase inhibitor; prognosis; young adultsNOYoung Adultchronic myeloid leukemiaLeukemia Myelogenous Chronic BCR-ABL PositivemedicineHumansBCR-ABL; Chronic myeloid leukemia; Prognosis; Tyrosine kinase inhibitors; Young adults; Adult; Age Factors; Aged; Aged 80 and over; Antineoplastic Agents; Female; Humans; Leukemia Myelogenous Chronic BCR-ABL Positive; Male; Middle Aged; Prospective Studies; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Spleen; Splenomegaly; Young AdultProtein Kinase InhibitorsAgedTyrosine kinase inhibitorsAdult patientsbusiness.industrymedicine.diseaseClinical trialBCR-ABL; Chronic myeloid leukemia; Prognosis; Tyrosine kinase inhibitors; Young adults; Adult; Age Factors; Aged; Aged 80 and over; Antineoplastic Agents; Female; Humans; Leukemia Myelogenous Chronic BCR-ABL Positive; Male; Middle Aged; Prospective Studies; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Spleen; Splenomegaly; Young Adult; Hematology; OncologyProspective StudieBCR-ABL; Chronic myeloid leukemia; Prognosis; Tyrosine kinase inhibitors; Young adults; Adult; Age Factors; Aged; Aged 80 and over; Antineoplastic Agents; Female; Humans; Leukemia Myelogenous Chronic BCR-ABL Positive; Male; Middle Aged; Prospective Studies; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Spleen; Splenomegaly; Young Adult; Medicine (all); Hematology; OncologyImmunologySplenomegalyBCR-ABL PositiveBCR-ABL chronic myeloid leukemia prognosis tyrosine kinase inhibitors young adultsprognosisbusinessSpleenYoung adultsMyelogenous
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Salvage Re-irradiation Options in Adult Medulloblastoma: A Case Report and Review of the Literature

2020

Background/aim Medulloblastoma is a rare tumor of adult age, while it occurs more frequently in children. Given the rarity, there is a lack of evidence for the treatment of recurrent disease. Few data are available about salvage re-irradiation collecting very heterogeneous series. Case report A 51-year-old male presented with headache, nausea, double vision, and gait disorders. A contrast-enhanced brain-MRI showed the presence of multifocal medulloblastoma. After surgery, adjuvant craniospinal radiotherapy was performed, chemotherapy was stopped due to toxicity. After 27 months, a new MRI and a Methionine-PET revealed a late pontocerebellar relapse; multidisciplinary board decided for a SBR…

MaleRe-IrradiationCancer Researchmedicine.medical_specialtyAdult MedulloblastomaNauseamedicine.medical_treatmentDiseaseGeneral Biochemistry Genetics and Molecular BiologyRe-Irradiation03 medical and health sciences0302 clinical medicineRecurrent diseaseHumansMedicineEffective treatmentCerebellar NeoplasmsSalvage TherapyPharmacologyMedulloblastomaChemotherapybusiness.industryAdult patientsMiddle Agedmedicine.diseaseMagnetic Resonance ImagingTumor BurdenTreatment OutcomePositron-Emission Tomography030220 oncology & carcinogenesisRadiologymedicine.symptombusinessResearch ArticleMedulloblastomaIn Vivo
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Finding ways to carry on: stories of vulnerability in chronic illness

2020

Purpose: In this study, we explore the lived experiences of chronic illness in four groups of patients; children with asthma, adolescents with diabetes, young adults with depression, and adult patients with chronic, obstructive pulmonary disease (COPD). Persons living with chronic illness are often designated as vulnerable. This study builds on the assumption that being vulnerable belongs to being human, and that vulnerability also might entail strength and possibilities for growth. Methods: A narrative analysis was undertaken to illuminate how experiences of vulnerability were narrated across the four patient groups, presenting four individual stories, one from each of the patient groups. …

MaleTime Factorslife worldvulnerabilityChronic illnessDevelopmental psychologyPulmonary Disease Chronic Obstructive0302 clinical medicineEmpirical Studies030212 general & internal medicineYoung adultChildlcsh:R5-920Narration030504 nursingDepressionHealth PolicyAge FactorsVDP::Medical disciplines: 700::Health sciences: 800Middle AgedSocial ParticipationPeer reviewVDP::Medisinske Fag: 700::Helsefag: 800phenomenologyFemaleLife worldlcsh:Medicine (General)0305 other medical sciencePsychologychronic illnessResearch ArticleAdultAdolescentPulmonary diseasenarrative analysisNarrative inquiryYoung Adult03 medical and health sciencesDiabetes MellitusHumansAgedAdult patientsLived experiencestoriesAsthmaIssues ethics and legal aspectsChronic DiseaseQuality of LifeFundamentals and skillsGerontology
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Improving the Diagnostic Accuracy of the Distress Thermometer: A Potential Role for the Impact Thermometer

2015

Abstract Context Screening for and management of distress in clinical practice is an important issue in the field of psycho-oncology. The Distress Thermometer (DT) is a common screening tool, but other methods recently have been proposed, with the aim of improving its diagnostic accuracy. Objectives To investigate the diagnostic accuracy of the DT alone and combined with the Impact Thermometer (IT), via the use of two possible combination methods. Methods A heterogeneous sample of 385 adult patients with cancer completed the DT, the IT, and the Brief Symptom Inventory-18. Results The results of the DT were comparable with those found in previous studies, indicating that the DT was adequate …

Malemedicine.medical_specialtyDiagnostic accuracyContext (language use)Sensitivity and SpecificityNeoplasmsHumansMedicineDistress ThermometerGeneral NursingPsychological TestsAdult patientsbusiness.industryMiddle AgedSurgeryClinical PracticeDistressAnesthesiology and Pain MedicineROC CurveThermometerPhysical therapyFemaleNeurology (clinical)businessCombination methodStress PsychologicalJournal of Pain and Symptom Management
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Post-remission treatment with allogeneic stem cell transplantation in patients aged 60 years and older with acute myeloid leukaemia: a time-dependent…

2015

Summary Background Acute myeloid leukaemia mainly affects elderly people, with a median age at diagnosis of around 70 years. Although about 50–60% of patients enter first complete remission upon intensive induction chemotherapy, relapse remains high and overall outcomes are disappointing. Therefore, effective post-remission therapy is urgently needed. Although often no post-remission therapy is given to elderly patients, it might include chemotherapy or allogeneic haemopoietic stem cell transplantation (HSCT) following reduced-intensity conditioning. We aimed to assess the comparative value of allogeneic HSCT with other approaches, including no post-remission therapy, in patients with acute…

Malemedicine.medical_specialtyTransplantation ConditioningGemtuzumab ozogamicinmedicine.medical_treatmentAntibodies Monoclonal HumanizedCOUNCIL AML11 TRIALEUROPEAN LEUKEMIANETInternal medicinehemic and lymphatic diseasesAntineoplastic Combined Chemotherapy ProtocolsmedicineClinical endpointINDUCTION CHEMOTHERAPYHumansTransplantation HomologousProspective StudiesADULT PATIENTS610 Medicine & healthBusulfanMETAANALYSISAgedMYELODYSPLASTIC SYNDROMEChemotherapyRISK-ADAPTED APPROACHbusiness.industryRemission InductionHematopoietic Stem Cell TransplantationInduction chemotherapyHematology1ST COMPLETE REMISSIONTotal body irradiationMiddle AgedGemtuzumabGEMTUZUMAB OZOGAMICINSurgeryFludarabineTransplantationSurvival RateLeukemia Myeloid AcuteAminoglycosidesTreatment OutcomeSURVIVALFemaleNeoplasm Recurrence LocalbusinessBusulfanVidarabinemedicine.drugLancet. Haematology
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