Search results for "ADULT"

showing 10 items of 17453 documents

Role of genetic polymorphisms in myocardial infarction at young age

2010

Acute myocardial infarction (AMI) in young adult presents a typical pattern of risk factors, clinical, angiographic and prognostic characteristics. In the last years we demonstrated that hemorheological profile is altered in these patients in a persistent way and independently of the number of risk factors and of the extent of coronary lesions. Thus, the hyperviscosity syndrome following AMI could be considered an intrinsic characteristic of these patients. Consequently it is possible to hypothesise the presence of a genetic background at the origin of this predisposition. If this background is able to influence the risk of ischemic heart disease, this should be particularly evident in youn…

cardiovascular risk factorsAdultMalePathologymedicine.medical_specialtyPhysiologyPopulationMyocardial InfarctionCoronary DiseaseSingle-nucleotide polymorphismDiseaseBiologyPolymorphism Single NucleotideConnexinsPhysiology (medical)Genetic predispositionmedicineHumansSNPGenetic Predisposition to DiseaseMyocardial infarctionAlleleeducationAged 80 and overInflammationeducation.field_of_studyHaplotypeHematologyMiddle AgedPyrinmedicine.diseaseInterleukin-10Platelet Endothelial Cell Adhesion Molecule-1Toll-Like Receptor 4Juvenile myocardial infarctiongenetic patternCytoskeletal ProteinsC-Reactive ProteinImmunologyFemaleCardiology and Cardiovascular MedicineClinical Hemorheology and Microcirculation
researchProduct

Relation between Tissue Factor Pathway Inhibitor Activity and Cardiovascular Risk Factors and Diseases in a Large Population Sample.

2021

Abstract Objective Tissue factor pathway inhibitor (TFPI) is a potent anticoagulant protein in the extrinsic coagulation pathway. In the present study, we aim to identify the cardiovascular determinants for total TFPI activity and its association with cardiovascular disease (CVD) and total mortality. Methods Total TFPI activity was assessed in a selection of the population-based Gutenberg Health Study (n = 5,000). Statistical analysis was performed to identify the determinants for total TFPI activity as well as the associations with CVD and mortality. Results Multivariable linear regression analysis identified smoking (β 0.095 [0.054–0.136]) as a positive determinant for total TFPI activity…

cardiovascular risk factorsAdultMalemedicine.medical_specialtyLipoproteinsPopulationpopulationCoronary Artery DiseaseTFPICoronary artery diseaseTissue factor pathway inhibitorDiabetes mellitusInternal medicinemedicineDiabetes MellitusHumansObesityProspective StudieseducationAgededucation.field_of_studyVENOUS THROMBOEMBOLISMbiologyPLASMAProportional hazards modelbusiness.industrySmokingFactor VWOMENHematologyMiddle Agedmedicine.diseaseObesitymortalitytotal TFPI activityESTROGENEndocrinologyMYOCARDIAL-INFARCTIONFACTOR-VCardiovascular DiseasesHeart Disease Risk Factorsbiology.proteinPopulation studyepidemiologyFemalebusinessThrombosis and haemostasis
researchProduct

Effects of n-3 Polyunsaturated Fatty Acids (ω-3) Supplementation on Some Cardiovascular Risk Factors with a Ketogenic Mediterranean Diet

2015

Background: the ketogenic diet (KD) has become a widely used nutritional approach for weight loss. Some of the KD’s positive effects on metabolism and cardiovascular risk factors are similar to those seen after n-3 polyunsaturated fatty acids (ω-3) supplementation. We hypothesized that a ketogenic Mediterranean diet with phytoextracts combined with ω-3 supplementation may have increased positive effects on cardiovascular risk factors and inflammation. Methods: We analyzed 34 male overweight subjects

cardiovascular risk factorsBlood GlucoseMaleMediterranean dietinflammatory cytokinesmedicine.medical_treatmentN-3 polyunsaturated fatty acidPharmaceutical ScienceOverweightDiet Mediterraneanchemistry.chemical_compoundRisk FactorsWeight lossDrug DiscoveryInsulinlcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)Adipositychemistry.chemical_classificationCardiovascular risk factors; Inflammatory cytokines; Ketogenic diet; N-3 polyunsaturated fatty acids; Omega-3; Weight loss; Drug Discovery3003 Pharmaceutical ScienceMiddle Agedn-3 polyunsaturated fatty acidsketogenic dietCardiovascular DiseasesCytokinesomega-3medicine.symptomDiet KetogenicPolyunsaturated fatty acidAdultmedicine.medical_specialtyInflammatory cytokineBiologyCardiovascular risk factorWeight loArticleInternal medicineFatty Acids Omega-3Weight LossmedicineHumansTriglyceridesAgedAdiponectinPlant ExtractsCholesterolDrug Discovery3003 Pharmaceutical Science<i>n</i>-3 polyunsaturated fatty acidsCholesterol LDLOverweightEndocrinologylcsh:Biology (General)chemistryDietary SupplementsUric acidKetogenic dietMarine Drugs
researchProduct

Prevalence and factors associated with circadian blood pressure patterns in hypertensive patients.

2009

Comment in Timing of antihypertensive therapy and circadian blood pressure pattern. [Hypertension. 2009] Timing of antihypertensive therapy and circadian blood pressure pattern. Almirall J, Martínez-Ocaña JC, Comas L. Hypertension. 2009 Jun; 53(6):e41; author reply e42. Epub 2009 May 4. Dipping comes of age: the importance of nocturnal blood pressure. [Hypertension. 2009]. Dipping comes of age: the importance of nocturnal blood pressure. O'Brien E. Hypertension. 2009 Mar; 53(3):446-7. Epub 2009 Jan 26.Nondipping in patients with hypertension. [Hypertension. 2009] Ambulatory blood pressure (BP) monitoring has become useful in the diagnosis and management of hypertensive individuals. In addit…

cardiovascular risk factorsMale:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Cardiovascular Agents::Antihypertensive Agents [Medical Subject Headings]Blood Pressure:Named Groups::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Cohort Studiescircadian blood pressure patternFactores de riesgo cardiovascularPrevalenceRegistries:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Prevalence [Medical Subject Headings]:Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings]Blood Pressure Monitoring AmbulatoryMiddle AgedCircadian Rhythm:Phenomena and Processes::Physiological Phenomena::Chronobiology Phenomena::Periodicity::Circadian Rhythm [Medical Subject Headings]AmbulatoryHypertension:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Monitoring Physiologic::Monitoring Ambulatory::Blood Pressure Monitoring Ambulatory [Medical Subject Headings]CardiologyFemaleCohort studyAdultmedicine.medical_specialtyAmbulatory blood pressurenocturnal blood pressure dip:Check Tags::Male [Medical Subject Headings]:Diseases::Cardiovascular Diseases::Vascular Diseases::Hypertension [Medical Subject Headings]Diabetes mellitusInternal medicine:Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Cardiovascular Physiological Phenomena::Hemodynamics::Blood Pressure [Medical Subject Headings]:Named Groups::Persons::Age Groups::Adult [Medical Subject Headings]Internal MedicinemedicineHumansCircadian rhythm:Named Groups::Persons::Age Groups::Adult::Aged [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models Statistical::Linear Models [Medical Subject Headings]Risk factorAntihypertensive AgentsAgedbusiness.industrymedicine.diseaseObesitySurgerycircadianBlood pressure:Check Tags::Female [Medical Subject Headings]Spain:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies [Medical Subject Headings]Linear Models:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Registries [Medical Subject Headings]businessHypertension (Dallas, Tex. : 1979)
researchProduct

PREVALENCE OF ARTERIAL HYPERTENSION AND CHARACTERISTICS OF NOCTURNAL BLOOD PRESSURE PROFILE OF ASTHMA PATIENTS ACCORDING TO THERAPY AND SEVERITY OF T…

2020

Background: several studies report an increased risk for asthmatic subjects to develop arterial hypertension and the relationship between these two diseases, frequently co-existing, still has some unclear aspects. Methods: The BADA (blood pressure levels, clinical features and markers of subclinical cardiovascular damage of asthma patients) study is aimed to evaluate the prevalence of the cardiovascular comorbidities of asthma and their impact on the clinical outcome. The main exclusion criteria were the presence of other respiratory diseases, current smoking, any contraindication to ambulatory blood pressure monitoring (ABPM). Results: The overall percentage of asthmatics having also hyper…

cardiovascular riskAdultMalemedicine.medical_specialtyAmbulatory blood pressurePatientsPhysiologyHealth Toxicology and Mutagenesislcsh:MedicineBlood PressureDisease030204 cardiovascular system & hematologyEssential hypertensionSeverity of Illness IndexArticlenocturnal dipping of blood pressure03 medical and health sciences0302 clinical medicineRisk FactorsDiabetes mellitusInternal medicinePrevalenceInternal MedicinemedicineHumans030212 general & internal medicineContraindicationAgedAsthmabusiness.industrylcsh:RPublic Health Environmental and Occupational Healthessential hypertensionOdds ratioasthmaBlood Pressure Monitoring AmbulatoryMiddle Agedmedicine.diseaseNocturnal blood pressureCircadian RhythmNocturnal dipping of blood pressure.Blood pressureHypertensioninhaled corticosteroid therapyFemaleCardiology and Cardiovascular MedicinebusinessBody mass indexJournal of Hypertension
researchProduct

Long-term positive airway pressure therapy is associated with reduced total cholesterol levels in patients with obstructive sleep apnea : data from t…

2020

Background and aim: Obstructive sleep apnea (OSA) is an independent risk factor for dyslipidemia. The current study examined the effects of positive airway pressure (PAP) treatment on lipid status in the European Sleep Apnea Database (ESADA). Methods: The prospective cohort study enrolled 1564 OSA subjects (74% male, mean age 54 ± 11y, body mass index (BMI) 32.7 ± 6.6 kg/m2 and apnea-hypopnea index (AHI) 40.3 ± 24.4 n/h) undergoing PAP therapy for at least three months (mean 377.6 ± 419.5 days). Baseline and follow-up total cholesterol (TC) from nine centers were analyzed. Repeated measures and logistic regression tests (adjusted for age, sex, weight changes, lipid lowering medication, PAP …

cardiovascular riskAdultMalemedicine.medical_specialtySettore MED/10 - Malattie Dell'Apparato RespiratorioPositive airway pressure03 medical and health sciences0302 clinical medicineInternal medicinePositive airway pressuremedicineCardiovascular risk Cholesterol Hypoxia Sleep apneaHumanspositive airway pressureProspective StudiesRisk factorProspective cohort studyHypoxiaAgedSleep Apnea ObstructiveFramingham Risk ScoreContinuous Positive Airway Pressurebusiness.industryhypoxiaSleep apneaSleep apneacholesterolGeneral MedicineMiddle Agedmedicine.diseasesleep apneaCardiovascular riskObstructive sleep apneaCardiovascular risk ; Cholesterol ; Hypoxia ; Positive airway pressure ; Sleep apnea.Cholesterol030228 respiratory systemPatient ComplianceFemaleHuman medicinebusinessBody mass index030217 neurology & neurosurgeryDyslipidemiaSleep medicine
researchProduct

Psychophysical burden and lack of support : Reasons for care workers’ intentions to leave their work in the Nordic countries

2021

Long-term care of older adults is currently suffering from a shortage of trained personnel and high turnover rates. Care work is poorly paid, demanding, increasingly time-bound and both mentally and physically burdensome. In this study, we examined the individual, organisational and economic factors that predict professional care workers’ intentions to leave their current employment, using the NORDCARE survey data (2015, N = 3801) collected in Denmark, Finland, Norway and Sweden. The respondents were mainly practical and assistant nurses. The analysis showed that the predictors of intentions to leave were similar in the four countries. The most consistent organisational predictors of leavin…

care worktyövoiman kysyntäSociology and Political Sciencetyöhyvinvointipitkäaikaishoitotyövoimantarveleaving intentionslong- term carevanhustenhuoltopsychophysical burden03 medical and health sciences0302 clinical medicineNursing050602 political science & public administrationhoiva-ala030212 general & internal medicinetyöelämäolder adults05 social sciencestyövoiman vaihtuvuus0506 political scienceterveydenhuoltohenkilöstöpsykofysiologiaLong-term careWork (electrical)Care workers8. Economic growthhoitohenkilöstölähihoitajatperushoitajathenkilöstöCare workvanhustenhuoltolaitoksetPsychologytyöpaikan vaihtoikääntyneethoitotyö
researchProduct

Development of a European consensus from dentists, dental hygienists and physicians on a standard for oral health care in care-dependent older people…

2020

ObjectivesThis study aimed to obtain a consensus on oral health policy, access to dental care, oral hygiene measures and training levels.BackgroundPoor oral health is widespread in care-dependent older people, but no consensus for a minimum standard of oral health care exists yet.MethodsThe e-Delphi approach was applied to a selected panel of interdisciplinary experts. Data analysis was based on three measurements: (a) ≥70% of experts’ opinion fall into category “agree or strongly agree,” (b) median score on the 5-point Likert scale ≥4, (c) interquartile range ≤1.ResultsA total of 31 experts from 17 European countries participated in this survey. Agreement was achieved for a compulsory dent…

care-dependent older adulte-Delphi studyInstitutionalised older adultsDelphi TechniqueDentistsDelphi methodgeriatric oral careOral Health0302 clinical medicine80 and overMedicine030212 general & internal medicine610 Medicine &amp; healthAged 80 and overinstitutionalised older adults.Care-dependent older adultsE-Delphi studyReference Standardsddc:617.6care-dependent older adults; e-Delphi study; geriatric oral care; institutionalised older adults; Aged; Aged 80 and over; Consensus; Delivery of Health Care; Delphi Technique; Dental Hygienists; Dentists; Europe; Humans; Reference Standards; Oral Health; PhysiciansEurope/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingDental Hygienistsmedicine.medical_specialtyConsensusOral hygieneRemovable prosthodontics03 medical and health sciencesstomatognathic systemSDG 3 - Good Health and Well-beingGeneral DentistryPhysicianscare-dependent older adultsHumansGeneral DentistryAgedbusiness.industryConflict of interest030206 dentistryFocus groupstomatognathic diseasesinstitutionalised older adultsGeriatric oral careFamily medicineddc:618.97Oral health careGeriatrics and GerontologybusinessOlder peopleDelivery of Health CareGerodontologyREFERENCES
researchProduct

Ikä, identiteetti ja ohjaava koulutus. Ikääntyvät pitkäaikaistyöttömät oppimisyhteiskunnan haasteena

2007

Piia Silvennoinen tutki väitöskirjassaan, millainen merkitys työvoimapoliittisella koulutuksella on ikääntyvien pitkäaikaistyöttömien elämässä. Koulutusten oletetaan parantavan ikääntyvien pitkäaikaistyöttömien työmarkkinakelpoisuutta ja elämänhallintaa. Silvennoinen haki vastausta siihen, miten ikääntyvät pitkäaikaistyöttömät itse suhtautuvat työvoimapoliittisiin koulutuksiin; onko niistä heille haittaa vai hyötyä. Silvennoinen kertoo, että koulutuksen hyödyllisyyttä arvioidaan sen työllistävän vaikutuksen kautta. – Mitä vähemmän koulutus työllistää, sitä enemmän myös sen muut merkitykset menettävät arvoaan ikääntyvien pitkäaikaistyöttömien elämässä, Silvennoinen toteaa. Nykyinen itseohjau…

career counsellingreflexive modernizationaikuiskoulutusOccupational Guidancetyövoimakoulutuselinikäinen oppiminentyöllistyminenlifelong learninglong-term unemploymenthaastatteluttyöttömättyömarkkinattyöttömyysAdult LearningkoulutusUnemploymentageingohjaava koulutuspitkäaikaistyöttömätidentiteettityövoimapitkäaikaistyöttömyysidentityikääntyneet
researchProduct

Reliability and Validity of The Finnish Version of The Boston Carpal Tunnel Questionnaire among Surgically Treated Carpal Tunnel Syndrome Patients

2019

Background and Aims: The Boston Carpal Tunnel Questionnaire is the most commonly used outcome measure in the assessment of carpal tunnel syndrome. The purpose of this study was to translate the original Boston Carpal Tunnel Questionnaire into Finnish and validate its psychometric properties. Materials and Methods: We translated and culturally adapted the Boston Carpal Tunnel Questionnaire into Finnish. Subsequently, 193 patients completed the Finnish version of the Boston Carpal Tunnel Questionnaire, 6-Item CTS Symptoms Scale, and EuroQol 5 Dimensions 12 months after carpal tunnel release. The Boston Carpal Tunnel Questionnaire was re-administered after a 2-week interval. We calculated cons…

carpal tunnel releaseMaleBoston Carpal Tunnel QuestionnairevaliditySYMPTOMSPsychometricsRESPONSIVENESS0302 clinical medicineQuality of lifeQUALITY-OF-LIFESurveys and QuestionnairesOutcome Assessment Health CareCarpal tunnel030212 general & internal medicineFinlandReliability (statistics)Outcome measuresMiddle AgedCarpal Tunnel Syndromemedicine.anatomical_structureFUNCTIONAL STATUSFemaleFunctional statusSymptom Assessmentmusculoskeletal diseasesAdultmedicine.medical_specialtyPsychometricsHANDVALIDATION03 medical and health sciencesmedicineCarpal tunnel releaseHumansTranslationsCarpal tunnel syndromeAgedreliabilitybusiness.industryFinnishReproducibility of ResultsRecovery of Function3126 Surgery anesthesiology intensive care radiologymedicine.diseasebody regionsSEVERITYCROSS-CULTURAL ADAPTATIONPhysical therapyDISABILITIESSurgeryTRANSLATIONbusiness030217 neurology & neurosurgeryScandinavian Journal of Surgery
researchProduct