Search results for "ADULT"

showing 10 items of 17453 documents

Transverse fracture-dislocation of the sacrum: a diagnostic pitfall and a surgical challenge.

2002

Transverse fracture-dislocations of the sacrum are rare. Associated lesions of the lumbosacral spine as well as neurological injuries are common. Conventional radiographs of the pelvis often fail to clearly visualize the fracture. Delayed diagnosis increases the risk of progressive neurological disfunction. True lateral sacral views and CT-scans with 3-dimensional reconstructions are very helpful in establishing the full extent of the injury. These examinations should be considered in all patients with a history of high energy trauma and clinical signs indicating lumbosacral injury, such as severe low back pain and neurological disturbances of the lower extremities. The management of transv…

musculoskeletal diseasesAdultMalemedicine.medical_specialtySacrumNerve rootBone ScrewsJoint DislocationsFracture Fixation InternalDeformityMedicineHumansSpinal canalPelvisPalsyLumbar Vertebraebusiness.industryGeneral Medicinemusculoskeletal systemSacrumLow back painInternal FixatorsSurgeryRadiographymedicine.anatomical_structureSpinal FracturesSurgeryFemalemedicine.symptomNervous System DiseasesbusinessLumbosacral jointActa chirurgica Belgica
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Movement Variability Increases With Shoulder Pain When Compensatory Strategies of the Upper Body Are Constrained

2017

[DE] This cross-sectional study analyzed the influence of chronic shoulder pain (CSP) on movement variability/kinematics during humeral elevation, with the trunk and elbow motions constrained to avoid compensatory strategies. For this purpose, 37 volunteers with CSP as the injured group (IG) and 58 participants with asymptomatic shoulders as the control group (CG) participated in the study. Maximum humeral elevation (Emax), maximum angular velocity (Velmax), variability of the maximum angle (CVEmax), functional variability (Func_var), and approximate entropy (ApEn) were calculated from the kinematic data. Patients' pain was measured on the visual analogue scale (VAS). Compared with the CG, …

musculoskeletal diseasesAdultMalemedicine.medical_specialtyShoulderCognitive NeuroscienceMovementShoulder painElbowBiophysicsExperimental and Cognitive PsychologyKinematicsHumeral elevation03 medical and health sciencesYoung Adult0302 clinical medicinePhysical medicine and rehabilitationmedicineElbowHumansOrthopedics and Sports MedicineVariabilityPain Measurement030222 orthopedicsMovement (music)business.industryUpper bodyElevationTorsoMiddle AgedTrunkBiomechanical Phenomenamedicine.anatomical_structureCross-Sectional StudiesFISICA APLICADAChronic shoulder painFemalebusinessNeuromuscular control system030217 neurology & neurosurgery
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Manometric assessment of oesophageal involvement in progressive systemic sclerosis, morphoea and Raynaud's disease.

1982

SUMMARY Oesophageal function was studied by radiography and manometry in fifty-one patients with progressive systemic sclerosis (PSS), fourteen patients with morphoea, twelve patients with Raynaud's disease and twenty-one normal subjects. Upper oesophageal sphincter pressure was not affected. Peristaltic contractions of the upper third of the oesophagus were significantly decreased in PSS and morphoea, but the lower two-thirds were affected only in PSS. Lower oesophageal sphincter pressure was significantly decreased in PSS but was normal in morphoea and Raynaud's disease. There was a significant correlation between oesophageal dysfunction and the duration of PSS. Manometry was better than …

musculoskeletal diseasesAdultMalemedicine.medical_specialtyTime FactorsOesophageal manometryAdolescentManometryRadiographyDermatologySkin DiseasesScleroderma LocalizedEsophagusstomatognathic systemLower oesophageal sphincter pressurePressureMedicineUpper oesophageal sphincter pressureHumansAgedScleroderma Systemicbusiness.industryProgressive systemic sclerosisRaynaud DiseaseMiddle Agedmedicine.diseaseeye diseasesRadiographystomatognathic diseasesRaynaud's diseaseFemaleUpper thirdRadiologyOesophageal functionbusinessThe British journal of dermatology
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Urethral Reconstruction in Anterolateral Thigh Flap Phalloplasty: A 93-Case Experience

2019

BACKGROUND: Urethral reconstruction in anterolateral thigh flap phalloplasty cannot always be accomplished with one flap, and the ideal technique has not been established yet. In this article, the authors' experience with urethral reconstruction in 93 anterolateral thigh flap phalloplasties is reported. METHODS: Ninety-three anterolateral thigh phalloplasties performed over 13 years at a single center were retrospectively reviewed to evaluate outcomes of the different urethral reconstruction techniques used: anterolateral thigh alone without urethral reconstruction (n = 7), tube-in-tube anterolateral thigh flap (n = 5), prelaminated anterolateral thigh flap with a skin graft (n = 8), antero…

musculoskeletal diseasesAdultMalemedicine.medical_specialtyTreatment outcomeSettore MED/19 - Chirurgia Plastica030230 surgeryRisk AssessmentTransgender PersonsFollow-Up StudieCohort Studies03 medical and health sciences0302 clinical medicineUrethraRetrospective StudieSex Reassignment SurgeryMedicineHumansReconstructive Surgical ProcedureRetrospective StudiesThigh surgeryWound HealingRadial forearm flapbusiness.industryFollow up studiesAnterolateral thighPlastic Surgery ProceduresMiddle Agedmusculoskeletal systemUrethra surgeryMyocutaneous Flapeye diseasesPeniSurgerybody regionsTreatment OutcomeThigh030220 oncology & carcinogenesisSurgeryFemalePhalloplastyTransgender PersonCohort StudiebusinessFollow-Up StudiesPenisHuman
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HLA Class II Differentiates Between Thyroid and Polyglandular Autoimmunity.

2015

The HLA class II genes are susceptibility genes for autoimmune endocrine diseases; however, scarce data are available pertaining to the determinants of genetic susceptibility to polyglandular autoimmunity (PGA). A total of 300 consecutive and unselected patients with either PGA or monoglandular autoimmune thyroid disease (AITD) and 100 healthy control subjects were genotyped for the HLA class II DRB1, -DQA1, and -DQB1 alleles. Compared to patients with AITD and controls, the HLA-DRB1*03 (pc =0.001), *04 (pc<0.001), -DQA1*03 (pc<0.001), and -DQB1*02 (pc =0.001) alleles were increased in patients with PGA. When dividing patients with Hashimoto's thyroiditis (HT) into those with PGA (PGA-HT) v…

musculoskeletal diseasesAdultMalemedicine.medical_specialtyendocrine system diseasesAdolescentEndocrinology Diabetes and MetabolismGraves' diseaseClinical BiochemistryThyroid GlandAutoimmunityImmunogeneticsHashimoto Diseasemedicine.disease_causeBiochemistryThyroiditisAutoimmunityYoung AdultEndocrinologyInternal medicineGenetic predispositionMedicineHumansHashimoto DiseaseGenetic Predisposition to DiseaseAlleleskin and connective tissue diseasesChildbusiness.industryBiochemistry (medical)ThyroidHistocompatibility Antigens Class IIInfantGeneral MedicineMiddle Agedmedicine.diseaseGraves DiseaseEndocrinologymedicine.anatomical_structureChild PreschoolImmunologyFemalebusinessHormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
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Cementless total hip replacement with subtrochanteric femoral shortening for severe developmental dysplasia of the hip.

2003

Total joint replacement in patients suffering from developmental dysplasia of the hip poses specific technical difficulties due to insufficient bone stock at the site of the original and secondary acetabulum and a narrow, cranially displaced proximal femur. Twelve hips with severe congenital dislocation (4 Crowe type II, 5 type III, 3 type IV) were treated with cementless, porous structured total hip replacement. The cup was implanted at the anatomic height, a femoral segment was resected below the minor trochanter to reduce the femoral component in all cases. One femoral component was exchanged for a longer stem after 2 months due to insufficient fit and fill. After a mean follow-up of 5.1…

musculoskeletal diseasesAdultMalemedicine.medical_specialtymedicine.medical_treatmentArthroplasty Replacement HipOsteotomymedicineHumansOrthopedics and Sports MedicineFemurFemurHip Dislocation CongenitalReduction (orthopedic surgery)Trochanterbusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseAcetabulumSurgeryRadiographyHarris Hip ScoreDysplasiaOrthopedic surgerySurgeryFemalebusinessArchives of orthopaedic and trauma surgery
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The Retrograde Tibial Nail: presentation and biomechanical evaluation of a new concept in the treatment of distal tibia fractures.

2013

Displaced distal tibia fractures require stable fixation while minimizing secondary damage to the soft tissues by the surgical approach and implants. Antegrade intramedullary nailing has become an alternative to plate osteosynthesis for the treatment of distal metaphyseal fractures over the past two decades. While retrograde intramedullary nailing is a standard procedure in other long bone fractures, only few attempts have been made on retrograde nailing of tibial fractures. The main reasons are difficulties of finding an ideal entry portal and the lack of an ideal implant for retrograde insertion. The Retrograde Tibial Nail (RTN) is a prototype intramedullary implant developed by our group…

musculoskeletal diseasesAdultMalemedicine.medical_specialtymedicine.medical_treatmentLong boneBone NailsOsteotomyProsthesis Designlaw.inventionIntramedullary rodFixation (surgical)lawmedicineHumansTibiaGeneral Environmental ScienceAgedOsteosynthesisbusiness.industryMiddle Agedmusculoskeletal systemSurgeryBiomechanical PhenomenaFracture Fixation IntramedullaryRadiographyTibial Fracturesmedicine.anatomical_structureTreatment OutcomeGeneral Earth and Planetary SciencesFemaleImplantAnklebusinessBone PlatesInjury
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Abnormalities in alpha-dystroglycan expression in MDC1C and LGMD2I muscular dystrophies

2004

We recently identified mutations in the fukutin related protein (FKRP) gene in patients with congenital muscular dystrophy type 1C (MDC1C) and limb girdle muscular dystrophy type 2I (LGMD2I). The sarcolemma of these patients typically displays an immunocytochemical reduction of alpha-dystroglycan. In this report we extend these observations and report a clear correlation between the residual expression of alpha-dystroglycan and the phenotype. Three broad categories were identified. Patients at the severe end of the clinical spectrum (MDC1C) were compound heterozygote between a null allele and a missense mutation or carried two missense mutations and displayed a profound depletion of alpha-d…

musculoskeletal diseasesAdultPathologymedicine.medical_specialtyNonsense mutationBlotting WesternDNA Mutational AnalysisMedizinCompound heterozygosityPolymerase Chain ReactionMuscular DystrophiesPathology and Forensic MedicineFetusDystroglycanmedicineMissense mutationHumansPentosyltransferasesMuscular dystrophyChildDystroglycansMuscle SkeletalGeneticsFukutin-related proteinMembrane GlycoproteinsbiologyProteinsmedicine.diseasemusculoskeletal systemImmunohistochemistryCytoskeletal ProteinsPhenotypeMutationbiology.proteinCongenital muscular dystrophyLimb-girdle muscular dystrophyRegular Articles
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A ten-year follow-up of the Reflection cementless acetabular component.

2008

We reviewed the long-term results at ten to 12 years of 118 total hip replacements in 109 patients using a second-generation hemispherical cementless acetabular component (Reflection) designed to address the problem of backside wear. Five patients (five hips) died and six patients (seven hips) were lost to follow-up. The remaining 98 patients (106 hips) had a mean age of 62.9 years (34.0 to 86.2) A rate of revision for aseptic loosening of 0.9%, and predictable results were found with respect to radiological evidence of fixation, lack of pain, walking ability, range of movement and function. One component was revised for aseptic loosening, and of the 101 hips (95.2%) that did not have a rev…

musculoskeletal diseasesAdultmedicine.medical_specialtyAcetabulum; Adult; Aged; Aged 80 and over; Arthroplasty Replacement Hip; Bone Cements; Equipment Failure Analysis; Follow-Up Studies; Hip Joint; Humans; Middle Aged; Osteoarthritis Hip; Prosthesis Design; Prosthesis Failure; Statistics as Topic; Time Factors; Hip ProsthesisTime FactorsArthroplasty Replacement HipStatistics as TopicProsthesis DesignOsteoarthritis HipmedicineHumansOrthopedics and Sports MedicineSurvival analysisPelvisFixation (histology)AgedAged 80 and overbusiness.industryBone CementsAcetabulumMiddle AgedConfidence intervalSurgeryProsthesis FailureEquipment Failure AnalysisReflection acetabular component hipmedicine.anatomical_structureAcetabular componentRadiological weaponCohortOrthopedic surgerySurgeryHip JointHip ProsthesisbusinessFollow-Up StudiesThe Journal of bone and joint surgery. British volume
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Clinical performance of a highly portable, scanning calcaneal ultrasonometer.

2001

The aim of this study was to establish a normative database, assess precision, and evaluate the ability to identify women with low bone mass and to discriminate women with fracture from those without for a highly portable, scanning calcaneal ultrasonometer: the QUS-2. Fourteen hundred and one Caucasian women were recruited for the study. Among them were 794 healthy women 25–84 years of age evenly distributed per 10-year period to establish a normative database. Of these, 171 aged 25–34 years were defined as the young normal group for the purpose of T-score determination. Precision was assessed within 1 day (short-term) and over a 16-week period (long-term) in 79 women aged 25–84 years. Five…

musculoskeletal diseasesAdultmedicine.medical_specialtyAgingHeelBone densityBone diseaseEndocrinology Diabetes and MetabolismPoint-of-Care SystemsPopulationOsteoporosisFractures BoneBone DensityReference ValuesmedicineHumanseducationFemoral neckAgedUltrasonographyBone mineralAged 80 and overeducation.field_of_studyLumbar Vertebraebusiness.industryFemur NeckReproducibility of ResultsMiddle Agedmedicine.diseaseSurgeryCalcaneusmedicine.anatomical_structureROC CurveOsteoporosisFemaleCalcaneusNuclear medicinebusinessOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
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