6533b7cffe1ef96bd125915d
RESEARCH PRODUCT
Manometric assessment of oesophageal involvement in progressive systemic sclerosis, morphoea and Raynaud's disease.
T.r. WeihrauchG. W. Kortingsubject
musculoskeletal diseasesAdultMalemedicine.medical_specialtyTime FactorsOesophageal manometryAdolescentManometryRadiographyDermatologySkin DiseasesScleroderma LocalizedEsophagusstomatognathic systemLower oesophageal sphincter pressurePressureMedicineUpper oesophageal sphincter pressureHumansAgedScleroderma Systemicbusiness.industryProgressive systemic sclerosisRaynaud DiseaseMiddle Agedmedicine.diseaseeye diseasesRadiographystomatognathic diseasesRaynaud's diseaseFemaleUpper thirdRadiologyOesophageal functionbusinessdescription
SUMMARY Oesophageal function was studied by radiography and manometry in fifty-one patients with progressive systemic sclerosis (PSS), fourteen patients with morphoea, twelve patients with Raynaud's disease and twenty-one normal subjects. Upper oesophageal sphincter pressure was not affected. Peristaltic contractions of the upper third of the oesophagus were significantly decreased in PSS and morphoea, but the lower two-thirds were affected only in PSS. Lower oesophageal sphincter pressure was significantly decreased in PSS but was normal in morphoea and Raynaud's disease. There was a significant correlation between oesophageal dysfunction and the duration of PSS. Manometry was better than radiography at detecting motor abnormalities, with a positivity of 86% compared with 66% for radiography. Oesophageal manometry should be employed routinely in the investigation of patients with suspected PSS or morphoea.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1982-09-01 | The British journal of dermatology |