Search results for "AFRICAN-AMERICAN"
showing 8 items of 8 documents
Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci
2012
To identify genetic factors contributing to type 2 diabetes (T2D), we performed large-scale meta-analyses by using a custom ∼50,000 SNP genotyping array (the ITMAT-Broad-CARe array) with ∼2000 candidate genes in 39 multiethnic population-based studies, case-control studies, and clinical trials totaling 17,418 cases and 70,298 controls. First, meta-analysis of 25 studies comprising 14,073 cases and 57,489 controls of European descent confirmed eight established T2D loci at genome-wide significance. In silico follow-up analysis of putative association signals found in independent genome-wide association studies (including 8,130 cases and 38,987 controls) performed by the DIAGRAM consortium id…
Incidence of Kidney Replacement Therapy and Subsequent Outcomes Among Patients With Systemic Lupus Erythematosus: Findings From the ERA Registry.
2022
RATIONALE AND OBJECTIVE: There is a dearth of data characterizing patients requiring kidney replacement therapy (KRT) for kidney failure due to systemic lupus erythematosus (SLE) and their clinical outcomes. The aim of this study was to describe trends in incidence and prevalence of KRT among these patients as well as to compare their outcomes to patients treated with KRT for diseases other than SLE.STUDY DESIGN: Retrospective cohort study based on kidney registry data.SETTING & PARTICIPANTS: Patients recorded in 14 registries of patients receiving kidney replacement therapy that provided data to the European Renal Association (ERA) Registry between 1992 and 2016.PREDICTOR: SLE as cause…
The relationships between school belonging and students’ motivational, social-emotional, behavioural, and academic outcomes in secondary education: a…
2019
This meta-analytic review examines the relationships between students' sense of school belonging and students' motivational, social-emotional, behavioural, and academic functioning in secondary education. Moreover, it examines to what extent these relationships differ between different student groups (grade level, SES), measurement instruments, and region. The meta-analysis included 82 correlational studies, published in peer-reviewed journals between 2000 and 2018. Results revealed, on average, a small positive correlation with academic achievement, and small to moderate positive correlations with motivational outcomes such as mastery goal orientations; with social-emotional outcomes such …
“What you do to Children Matters”: Motherhood in Toni Morrison's God Help the Child
2015
Toni Morrison’s latest novel, God Help the Child, explores the damaging effects of racism on motherhood and the dramatic impact of toxic mothering upon children. The institution of patriarchal motherhood fails to enact the critical tasks of motherwork —preservation, nurturance and cultural bearing, while mothering is a potential site of empowerment of black children and African American culture. African American authoritarian parenting style, associated with patriarchal motherhood, has a correlation with diverse factors, such as the legacy of slavery and its survival strategies, low-income and/or single-parent households and the disruption of the motherline. Motherhood distorted by racism c…
A Chain of Voices: A "Masters and Slaves" Narrative
2022
Because no less than thirty different narrators take turns to tell us the story of a slave revolt, A Chain of Voices can be read as Brink's attempt at revisiting the classical "slave narrative", turning it into a polyphonic "masters and slaves" narrative in which everyone is given a say. This article examines how this polyphonic, and even multifocal, mode of narration enables Brink to write back to both classical slave narratives and to their twentieth-century counterparts, the neo-slave narratives. What it suggests is that although A Chain of Voices bears many resemblances to neo-slave narratives in terms of form, especially because of its recourse to polyphony, it is also extremely close …
Meanings of travel in the musical discourse of blues: Roosevelt “Grey Ghost” Williams and “Lonesome Traveller”
2016
El objetivo de este artículo es investigar, desde una perspectiva comunicativa, socio-semiótica y etnomusicológica, la construcción de sentido sobre el viaje y el estilo de vida itinerante (hobo) en el discurso musical del blues. Primero realizaremos una contextualización histórica del viaje en la tradición afroamericana, y después analizaremos el caso del legendario músico texano Roosevelt «Grey Ghost» Williams (1903-1996) y de su composición «Lonesome Traveller» («viajero solitario»), en la que se representa el sujeto y estilo de vida hobo (trabajador migrante y sin hogar). En ese proceso, discutiremos el sentido del viaje como imposición y el sentido del viaje como signo de independencia…
Rase un autorība izbēgušo vergu naratīvos (Fr. Duglass un H. Džeikobsa)
2017
Izbēgušo vergu naratīvi ir izveidojuši nozīmīgu pamatu 19. gadsimta Afro-Amerikāņu literatūrā, sniedzot vērtīgu attēlojumu par melnādaino vergu nepārtraukto cīņu dienvidu štatos, ar mērķi saglabāt identitāti un iegūt brīvību, tādējādi veicinot izpratni starp ziemeļu štata cilvēkiem par šaušalīgajiem notikumiem, kas norisinās verdzības iestādēs. Līdz ar to pašreizējā pētījuma mērķis ir veikt dzimtes un rases balstītu salīdzinājumu starp vergu naratīviem (Frederiks Duglass un Harieta Džeikobsa), un atbildēt uz galveno pētījuma jautājumu, nosakot kā abu dzimuma autori risināja ar rasi un dzimti saistītās problēmas. Lai sasniegtu uzstādīto mērķi, tika izvēlēti attiecīgi metodiskie paņēmieni, pr…
Prevalence of HPV infection in racial-ethnic subgroups of head and neck cancer patients
2017
Abstract The landscape of human papillomavirus (HPV) infection in racial/ethnic subgroups of head and neck cancer (HNC) patients has not been evaluated carefully. In this study, a meta-analysis examined the prevalence of HPV in HNC patients of African ancestry. Additionally, a pooled analysis of subject-level data was also performed to investigate HPV prevalence and patterns of p16 (CDNK2A) expression amongst different racial groups. Eighteen publications (N = 798 Black HNC patients) were examined in the meta-analysis, and the pooled analysis included 29 datasets comprised of 3129 HNC patients of diverse racial/ethnic background. The meta-analysis revealed that the prevalence of HPV16 was h…