Search results for "AHA"
showing 10 items of 1702 documents
Corporate boards and ownership structure: Evidence from Sub-Saharan Africa
2014
This study examines the relationship between board structure and ownership structure for firms listed on the stock exchanges of twelve Sub-Saharan African countries, using data for the period 2006–2009. We find that ownership concentration, foreign ownership and managerial ownership are negativelyassociated with board size. We also find that government ownership is positively associated with the proportion of outside directors while ownership concentration is negatively associated with the proportion of outside directors. These results emphasize that board and ownership structure are both corporate governance mechanisms that are used as substitutes to one another in reducing agencyproblems.
A Culturally Sensitive Approach to Promoting Initial Literacy Development in Africa : Ongoing and Planned Research and Development at the University …
2017
A four-year research and development program at CAPOLSA (the Centre for the Promotion of Literacy in Sub-Saharan Africa) was inspired by widespread dissatisfaction with poor literacy outcomes of mass basic schooling in Zambia and sought to test the generalizability of a scientifically grounded, computer-mediated instructional resource developed in Finland, for effective intervention in an African society where different linguistic and educational conditions obtain. Specific challenges and opportunities posed by the local sociocultural context included the prevalence of multilingualism, the relatively transparent orthographies of local languages, and poor infrastructure of the public school …
Digital materialities in the diasporic mourning of migrant death
2019
This article examines memorialization among the family and friends of those who have died at the world’s deadliest border in the Mediterranean Sea. Digital media platforms are central spaces for new, innovative forms of coping with ambiguous loss or the inability to mourn over a dead body. The analysis focuses on the role of digital media technologies and the relationship between digital and material elements in memorialization. I examine the creation and circulation of digital objects of memorialization: visual assemblages in which the material and digital intertwine. The analysis demonstrates that digital media practices are not separate from the material world, nor do they make mourning …
Vibrio Proteases for Biomedical Applications: Modulating the Proteolytic Secretome of V. alginolyticus and V. parahaemolyticus for Improved Enzymes P…
2019
Proteolytic enzymes are of great interest for biotechnological purposes, and their large-scale production, as well as the discovery of strains producing new molecules, is a relevant issue. Collagenases are employed for biomedical and pharmaceutical purposes. The high specificity of collagenase-based preparations toward the substrate strongly relies on the enzyme purity. However, the overall activity may depend on the cooperation with other proteases, the presence of which may be essential for the overall enzymatic activity, but potentially harmful for cells and tissues. Vibrios produce some of the most promising bacterial proteases (including collagenases), and their exo-proteome includes s…
Regional Variation of Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacterales, Fluoroquinolone-Resistant Salmonella enterica and Methicill…
2020
Background: Antimicrobial resistance (AMR) thwarts the curative power of drugs and is a present-time global problem. We present data on antimicrobial susceptibility and resistance determinants of bacteria the WHO has highlighted as being key antimicrobial resistance concerns in Africa, to strengthen knowledge of AMR patterns in the region. Methods: Blood, stool, and urine specimens of febrile patients, aged between ≥ 30 days and ≤ 15 years and hospitalized in Burkina Faso, Gabon, Ghana, and Tanzania were cultured from November 2013 to March 2017 (Patients > 15 years were included in Tanzania). Antimicrobial susceptibility testing was performed for all Enterobacterales and Staphylococcus aur…
Urban dynamics, mobilities and transport in the Algerian Southwest (wilayas of Adrar and Bechar)
2012
Between a regional perspective of the territorial (spatial) planning and a geopolitical vision of the region " Sahel, the Maghreb ", the Algerian State made a commitment since the second decade of its independence not only to develop transport in the Saharan zones but also to set up the necessary equipments for the economical and social development of these zones, by serving almost the totality of the urban areas. In the Southwest, this dynamics remodelled profoundly the relational space in Saoura, Gourara and Touat.Structured formerly by the roads of the trans-Saharan caravan business, this space opens up, attributes new functions and becomes urbanized. A new reorganization of the space is…
Extracellular Albumin and Endosomal Ions Prime Enterovirus Particles for Uncoating That Can Be Prevented by Fatty Acid Saturation
2019
ABSTRACT There is limited information about the molecular triggers leading to the uncoating of enteroviruses under physiological conditions. Using real-time spectroscopy and sucrose gradients with radioactively labeled virus, we show at 37°C, the formation of albumin-triggered, metastable uncoating intermediate of echovirus 1 without receptor engagement. This conversion was blocked by saturating the albumin with fatty acids. High potassium but low sodium and calcium concentrations, mimicking the endosomal environment, also induced the formation of a metastable uncoating intermediate of echovirus 1. Together, these factors boosted the formation of the uncoating intermediate, and the infectiv…
Comprehensive analysis of a Vibrio parahaemolyticus strain extracellular serine protease VpSP37
2015
Proteases play an important role in the field of tissue dissociation combined with regenerative medicine. During the years new sources of proteolytic enzymes have been studied including proteases from different marine organisms both eukaryotic and prokaryotic. Herein we have purified a secreted component of an isolate of Vibrio parahaemolyticus, with electrophoretic mobilities corresponding to 36 kDa, belonging to the serine proteases family. Sequencing of the N-terminus enabled the in silico identification of the whole primary structure consisting of 345 amino acid residues with a calculated molecular mass of 37.4 KDa. The purified enzyme, named VpSP37, contains a Serine protease domain be…
Nile Basin Climates
2009
The climate of the Nile Basin is characterised by a strong latitudinal wetness gradient. Whereas the areas north of 18°N remain dry most of the year, to the south there is a gradual increase of monsoon precipitation amounts. Rainfall regimes can be divided into 9 types, among which summer peak regimes dominate. In the southern half of the basin, mesoscale circulation features and associated contrasts in local precipitation patterns develop as a result of a complex interplay involving topography, lakes and swamps. Precipitation changes and variability show up as 3 distinct modes of variability. Drying trends since the 1950s are found in central Sudan and to some extent the Ethiopian Highland…
First Record of the Nematode Physaloptera squamatae in the Helminth Community of the Introduced Anole Anolis grahami (Polychrotidae) on Bermuda
2021
The gastrointestinal helminth communities of five populations of Anolis grahami, an introduced anole on Bermuda, were surveyed to determine the prevalence, abundance, and species diversity of parasites in these reptiles. Only three nematode species were found, Atractis scelopori, Parapharyngodon cubensis, and Physaloptera squamatae. This species, P. squamatae, is recorded for the first time in Anolis grahami on Bermuda, probably introduced through its arthropod intermediate host. The role of the host A. grahami as a “spillover” agent for these parasites is discussed.