Search results for "ALAT"

showing 10 items of 4241 documents

Diagnostic problems and postnatal follow-up in congenital toxoplasmosis

2007

Aim. In order to assess the consequences of different clinica] approaches in the prenata] management of congenital toxoplasmosis, we retrospectively reviewed 58 pregnant women with Toxoplasma seroconversion and prospec­ tively enrolled their 59 infants, referred to us from 1999 to 2004. Metbods. Data on clinica!, laboratocy and de­ mographic characteristics of the pregnant women were collected. Their children were entered intoa 48-month follow-up progcamme in which clinica , instrumental, ophthalmo­ logic and serologic evaluations were carried out at birth, at 1, 3, 6, 9, 15, 18, 24, 36 and at 48 months of life. Paediatric treatment with Spiramycin alone or alternated with Pyrime­ thamine-S…

AdultAdolescentSettore MED/17 - Malattie InfettiveAntiprotozoal AgentsSulfadiazinePolymerase Chain ReactionToxoplasmosis CongenitalAntimalarialsPregnancyAnimalsHumansProspective StudiesSicilyRetrospective StudiesInfantToxoplasmosis Diagnostic stepsInfectious Disease Transmission VerticalPyrimethamineTreatment OutcomeImmunoglobulin MImmunoglobulin GPregnancy Complications ParasiticAmniocentesisCoccidiostatsDrug Therapy CombinationFemalePregnancy TrimestersBiomarkersFollow-Up Studies
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[Herpes Zoster and its prevention in Italy. Scientific consensus statement].

2014

In this paper, an Italian group of experts presents a revision of the available data about epidemiology and prevention of Herpes Zoster (HZ). HZ is an acute viral diseases caused by the reactivation of Varicella Zoster Virus (VZV). HZ is characterized by neurological and dermatological symptoms with a dermatomeric localization. The reactivation of the virus from the latent status in the sensitive ganglia increases with age and failing cell mediated immunity. In Europe, more than 95% of adults presents antibodies against VZV. Incidence of HZ is similar all over the world, related to the age of the population: from 2-3/1000 persons/year in the age group 20 to 50 years to 5/1000 in the 60 year…

AdultAged 80 and overClinical Trials as TopicEvidence-Based MedicineSettore MED/17 - Malattie InfettiveIncidenceSocio-culturaleNeuralgia Postherpeticconsensus statementMiddle AgedSettore MED/42 - Igiene Generale E ApplicataHerpes ZosterAge DistributionItalyRisk Factors80 and overNeuralgiaHerpes Zoster VaccineHumansAdult; Age Distribution; Aged; Aged 80 and over; Clinical Trials as Topic; Evidence-Based Medicine; Herpes Zoster; Herpes Zoster Vaccine; Humans; Incidence; Italy; Middle Aged; Neuralgia Postherpetic; Risk Factors; SicilyPostherpeticSicilyprevention of herpes zosterAgedIgiene e sanita pubblica
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Ultrasonography-guided central venous catheterisation in haematological patients with severe thrombocytopenia

2012

BACKGROUND: Cannulation of the internal jugular vein (CVC) is a blind surface landmark-guided technique that could be potentially dangerous in patients with very low platelet counts. In such patients, ultrasonography (US)-guided CVC may be a valid approach. There is a lack of published data on the efficacy and safety of urgent US-guided CVC performed in haematological patients with severe thrombocytopenia. MATERIALS AND METHODS: We retrospectively studied the safety of urgent CVC procedures in haematological patients including those with severe thrombocytopenia (platelet count <30×10(9)/L). From January 1999 to June 2009, 431 CVC insertional procedures in 431 consecutive patients were evalu…

AdultAged 80 and overMaleCatheterization Central VenousAdolescentOriginal ArticlesMiddle AgedSeverity of Illness IndexThrombocytopeniaSettore MED/15 - Malattie Del SangueSettore MED/18 - Chirurgia Generalecentral venous catheterisation ultrasound Seldinger technique low platelet count haematological malignancyHumansFemaleAgedRetrospective StudiesUltrasonography
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Clinical-anamnestic and instrumental data in outpatients suffering from venous disease

1995

The authors studied 200 consecutive outpatients with symptoms due to venous disease of the lower limbs. All the patients underwent anamnestic, clinical and instrumental evaluation (c.w. Doppler velocimetry and strain-gauge plethysmography). The results of this study showed that some anamnestic and clinical data are significantly related to venous disease detected by instrumental techniques. The superficial and deep vein hypertension were, instead, correlated to oral contraceptive use.

AdultAged 80 and overMaleLegSettore MED/09 - Medicina InternaAdolescentMiddle AgedSettore MED/11 - Malattie Dell'Apparato CardiovascolarePlethysmographyAdolescent Adult Aged Aged 80 and over Blood Flow Velocity Contraceptives Oral/adverse effects Female Humans Hypertension/chemically induced Laser-Doppler Flowmetry Leg/blood supply Male Medical History Taking Middle Aged Morbidity Outpatients* Phlebitis/diagnosis Phlebitis/epidemiology Phlebitis/etiology* Plethysmography Pregnancy Retrospective Studies Risk FactorsPregnancyRisk FactorsHypertensionOutpatientsLaser-Doppler FlowmetryHumansFemaleMorbidityMedical History TakingPhlebitisBlood Flow VelocityAgedContraceptives OralRetrospective Studies
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TLR2 and age-related diseases: potential effects of Arg753Gln and Arg677Trp polymorphisms in acute myocardial infarction.

2008

ABSTRACT Inflammation is a key component of immune system. It is involved in both defense and pathophysiological events maintaining the dynamic homeostasis of host organism. Its function is controlled by innate immunity genes. Both their polymorphisms and environmental conditions give rise to different phenotypes in human population. Proinflammatory genotype may be beneficial in early life but not in old people. With advancing age, indeed, it increases the vulnerability and the intensity to inflammatory reactions responsible for the chronic inflammatory diseases, such as atherosclerosis and myocardial infarction (MI). Several studies have looked for detecting a genetic risk profile that mig…

AdultAgingSettore MED/09 - Medicina InternaGenotypePopulationMyocardial InfarctionInflammationPolymorphism Single NucleotideProinflammatory cytokineImmune systemGene FrequencyMedicineHumansMyocardial infarctioneducationSettore MED/04 - Patologia Generaleeducation.field_of_studyInnate immune systembusiness.industryMiddle Agedmedicine.diseaseSettore MED/11 - Malattie Dell'Apparato CardiovascolareToll-Like Receptor 2TLR2Amino Acid SubstitutionItalyTLR2age-related diseasespolymorphismsacute myocardial infarction.PharmacogenomicsCase-Control StudiesImmunologyGeriatrics and Gerontologymedicine.symptombusinessRejuvenation research
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[Prevalence of pericardial effusion in subjects with rheumatoid arthritis: an echocardiographic study].

1994

We used echocardiography to determine the prevalence of pericardial effusion in rheumatoid arthritis (RA) patients without cardiac systems and compared our results to those obtained in a control group of age-matched subjects. Thirty-six patients with RA (6 men, 30 women; mean age 51 +/- 11 years) were selected from a patient population in treatment at our outpatient Rheumatology Clinic. None of the patients had any symptoms of cardiac disease, and all patients with signs and/or systems of extracardiac disease were excluded from the study. The control group consisted of 60 volunteers (mean age 51 +/- 12 years) randomly selected from a larger group of subjects with neither symptoms, signs and…

AdultArthritis RheumatoidMaleAdult Arthritis Rheumatoid/complications* Cross-Sectional Studies Echocardiography* Female Humans Male Middle Aged Pericardial Effusion/diagnosis Pericardial Effusion/epidemiology* Pericardial Effusion/etiology Time FactorsSettore MED/09 - Medicina InternaCross-Sectional StudiesTime FactorsEchocardiographyHumansFemaleMiddle AgedSettore MED/11 - Malattie Dell'Apparato CardiovascolarePericardial EffusionAnnali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna
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Carotid intima-media thickness measurement through semi-automated detection software and analysis of vascular walls

2013

AIM: The aim of the present study was to compare the semi-automatic measurement of carotid intima thickness (RFQIMT - Esaote, Italy), with the conventional method. METHODS: We enrolle 81 patients, mean age 46 years ±15, with no history of cardio-cerebrovascular events and we assessed the traditional cardiovascular risk factors. We examined the IMT of the common carotid artery with manual and RFQIMT method (based on the "Radio Frequency" signal), according to the ASE protocol. RESULTS: Semi-automatic measurement was on average lower than manual measurement (617 μm ±191 vs. 676 μm ± 222) with a statistically significant difference (P<0.01). In agreement with manual measurements, the values of…

AdultAutomation LaboratoryCarotid Artery DiseasesCarotid Artery CommonCarotid intima media thickness - Radio frequency identification device - Cardiovascular diseaseAge FactorsMiddle AgedCarotid Intima-Media ThicknessSettore MED/11 - Malattie Dell'Apparato CardiovascolarePredictive Value of TestsRisk FactorsImage Interpretation Computer-AssistedHumans
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The impact of orthognathic surgery on quality of life in individuals with oral clefts

2021

Summary Background/objectives To evaluate the relationships between individual, environmental, clinical factors and oral health-related quality of life (OHRQoL) in patients with cleft lip and palate (CLP) following orthognathic surgery. Materials and methods A follow-up study was conducted involving 69 adults with unilateral and bilateral CLP under orthodontic treatment. Interviews and oral examinations were conducted prior to orthognathic surgery (T0) to evaluate age, gender, psychological well-being, dental caries, malocclusion, social support, social networks, family income and education and OHRQoL. All participants were reviewed after 6 months (T1) to re-assess psychological well-being,…

AdultBiopsychosocial modelCleft Lipmedicine.medical_treatmentOrthognathic surgeryDentistryOral HealthOrthodonticsDental Caries03 medical and health sciencesSocial support0302 clinical medicineQuality of lifeSurveys and QuestionnairesFISSURA LÁBIOPALATINAmedicineHumansIn patientProspective Studies030223 otorhinolaryngologyProspective cohort studybusiness.industryOrthognathic Surgery030206 dentistrymedicine.diseasehumanitiesCleft PalateQuality of LifeOral examinationMalocclusionbusinessMalocclusionFollow-Up StudiesEuropean Journal of Orthodontics
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Sleep apnoea severity independently predicts glycaemic health in nondiabetic subjects: the ESADA study

2014

Abstract: Obstructive sleep apnoea (OSA) is associated with increased risk of dysglycaemia but the intimate link of these conditions with obesity makes discerning an independent relationship between them challenging. Glycosylated haemoglobin (HbA1c) levels predict adverse cardiovascular outcomes in nondiabetics but there is a lack of population-level data exploring the relationship of HbA1c with OSA. A cross-sectional analysis of 5294 participants in the multinational European Sleep Apnoea Cohort (European Sleep Apnoea Database) study was performed, assessing the relationship of OSA severity with HbA1c levels in nondiabetic subjects, with adjustment for confounding factors. HbA1c levels cor…

AdultBlood GlucoseMalePulmonary and Respiratory Medicinemedicine.medical_specialtyAdolescentCross-sectional studyPolysomnographyintermittent hypoxia insulin resistance diabetes obesityBlood PressurePolysomnographySettore MED/10 - Malattie Dell'Apparato Respiratoriota3111Young Adultstomatognathic systemInternal medicineDiabetes MellitusmedicineHumansProspective StudiesSleep studyHypoxiaAgedAged 80 and overGlycated HemoglobinSleep Apnea ObstructiveAnthropometrymedicine.diagnostic_testbusiness.industryConfoundingSleep apneaOdds ratioMiddle Agedmedicine.diseasenervous system diseasesrespiratory tract diseasesEuropeCross-Sectional StudiesTreatment OutcomeQuartileCardiovascular DiseasesHyperglycemiaMultivariate AnalysisCohortPhysical therapyFemaleHuman medicinebusinessEuropean Respiratory Journal
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Lack of plasmic beta-endorphin response to a gastronomic meal in healthy humans.

1991

Abstract In order to study the relationship between the endogenous opiate system and food intake in man, plasma concentrations of beta-endorphin were measured in ten healthy subjects. Time course of beta-endorphinemia was compared under the following conditions: basal (fasting), after an injection of pentagastrin (6 μg/kg), or after a gastronomic meal. No changes in plasma beta-endorphin or ACTH concentrations were observed with pentagastrin nor after the meal, despite the combination of very high sensory pleasure with intake of a very large amount of food. It is concluded that blood beta-endorphin concentration is not a sensitive index of the effects of food intake on the endogenous opioid…

AdultBlood GlucoseMaleendocrine systemmedicine.medical_specialtyHungerAppetiteExperimental and Cognitive PsychologyPeptide hormoneBehavioral Neurosciencechemistry.chemical_compoundEatingInternal medicinemedicineHumansPalatabilityEndogenous opioidMealbusiness.industrydigestive oral and skin physiologybeta-EndorphinPentagastrinAffectEndocrinologychemistryBasal (medicine)TasteReceptors Opioidbeta-EndorphinOpiatebusinessArousalEnergy Intakehormones hormone substitutes and hormone antagonistsmedicine.drugPhysiologybehavior
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