Search results for "ALLERGIC RHINITIS"

showing 9 items of 59 documents

The effect of allergen immunotherapy in the onset of new sensitizations: a meta-analysis.

2017

Background Although the preventive efficacy of allergen immunotherapy (AIT) in the onset of new allergen sensitizations has been asserted by many reviews, position papers, and consensus conferences, the evidence available is from only 3 studies. The objective of this work was a systematic review to evaluate the preventive efficacy of AIT in the onset of new allergen sensitizations. The end-point was the risk difference (RD) in the onset of new allergen sensitizations between patients treated with AIT and pharmacotherapy. Methods Computerized bibliographic searches of MEDLINE, EMBASE, and the Cochrane Library (until November 30th, 2016) were done. Random-effects and fixed-effects model meta-…

allergic rhinitisPyroglyphidaenew allergen sensitizationasthmameta-analysiDesensitization ImmunologicAnti-Allergic Agentsallergen immunotherapyHypersensitivityAnimalsHumansImmunizationAntigens DermatophagoidesChildRandomized Controlled Trials as TopicInternational forum of allergyrhinology
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Endotyping allergic rhinitis in children: A machine learning approach.

2021

Introduction: The diversity of allergic rhinitis (AR) phenotypes is particularly evident in childhood, suggesting the need to analyze and identify new approaches to capture such clinical heterogeneity. Nasal cytology (NC) is a very useful diagnostic tool for identifying and quantifying nasal inflammation. Data-driven approaches such as latent class analysis (LCA) assign subjects to classes based on their characteristics. We hypothesized that LCA based on NC, including the assessment of neutrophils, eosinophils, and mast cells, may be helpful for identifying AR endotypes in children. Methods: A total of 168 children were enrolled. Sociodemographic characteristics and detailed medical history…

allergic rhinitisallergic rhinitis children endotypes latent class analysis nasal cytologyImmunologyRhinitis Allergic SeasonalRhinitis Allergicnasal cytologyEosinophilsMachine LearningchildrenendotypesPediatrics Perinatology and Child Healthlatent class analysisImmunology and AllergyHumansRhinitisSkin TestsPediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology
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Validity, reliability, and responsiveness of daily monitoring visual analog scales in MASK-air®

2021

International audience; Background: MASK-air® is an app that supports allergic rhinitis patients in disease control. Users register daily allergy symptoms and their impact on activities using visual analog scales (VASs). We aimed to assess the concurrent validity, reliability, and responsiveness of these daily VASs. Methods: Daily monitoring VAS data were assessed in MASK-air® users with allergic rhinitis. Concurrent validity was assessed by correlating daily VAS values with those of the EuroQol-5 Dimensions (EQ-5D) VAS, the Control of Allergic Rhinitis and Asthma Test (CARAT) score, and the Work Productivity and Activity Impairment Allergic Specific (WPAI-AS) Questionnaire (work and activi…

allergic rhinitisreliabilityresponsivenessRespiratory Medicine and Allergy610Public Health Global Health Social Medicine and EpidemiologyReviewallergic rhinitis; mobile health; reliability; responsiveness; visual analog scalesRC581-607Settore MED/10 - Malattie Dell'Apparato Respiratorioallergic rhinitis mobile health reliability responsiveness visual analog scalesFolkhälsovetenskap global hälsa socialmedicin och epidemiologiImmunologic diseases. Allergy[SDV.IMM.ALL]Life Sciences [q-bio]/Immunology/Allergologyvisual analog scalesmobile health600 Technik Medizin angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und GesundheitLungmedicin och allergi
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Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis – A EUFOREA-ARIA-EPOS-AIRWAYS IC…

2017

Precision medicine (PM) is increasingly recognized as the way forward for optimizing patient care. Introduced in the field of oncology, it is now considered of major interest in other medical domains like allergy and chronic airway diseases, which face an urgent need to improve the level of disease control, enhance patient satisfaction and increase effectiveness of preventive interventions. The combination of personalized care, prediction of treatment success, prevention of disease and patient participation in the elaboration of the treatment plan is expected to substantially improve the therapeutic approach for individuals suffering from chronic disabling conditions. Given the emerging dat…

allergic rhinitis; integrated care pathway; precision medicine; rhinosinusitisAllergyRhinosinusitisDiseaseAllergic rhinitis0302 clinical medicineQUALITY-OF-LIFEMedicineImmunology and Allergy030223 otorhinolaryngologySinusitisNASAL POLYPOSISRhinitisPrecision medicineintegrated care pathway3. Good healthAlgorithmREAL-LIFEIMPACT OUTCOMESARIA and EPOS working groups1107 ImmunologyDISEASESGA(2)LENDisease Progressionallergic rhinitiLife Sciences & BiomedicineENDOSCOPIC SINUS SURGERYAlgorithmsHumanIntegrated care pathwayallergic rhinitis; integrated care pathway; precision medicine; rhinosinusitis; Adult; Algorithms; Chronic Disease; Disease Progression; Humans; Precision Medicine; Rhinitis Allergic; Sinusitis; Young Adult; Immunology and Allergy; ImmunologyAdultmedicine.medical_specialtyprecision medicineImmunologyrhinosinusitiPHENOTYPESVALIDATIONYoung Adult03 medical and health sciencesTherapeutic approachAllergicPatient satisfactionQuality of life (healthcare)HumansSinusitisPatient participationIMMUNOTHERAPYIntensive care medicinerhinosinusitisAsthmaScience & Technologyallergic rhinitis; integrated care pathway; precision medicine; rhinosinusitis; Immunology and Allergy; Immunologyallergic rhinitisbusiness.industrymedicine.diseasePrecision medicineSinusitiRhinitis AllergicSEVERITY030228 respiratory system3121 General medicine internal medicine and other clinical medicineChronic DiseasePhysical therapyASTHMAbusiness
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Novel Perspectives in the Detection of Oral and Nasal Oxidative Stress and Inflammation in Pediatric United Airway Diseases

2010

United airway disease (UAD) concept proposed that asthma and rhinitis are both different clinical manifestation of a single inflammatory process. The aim of this study is to assess in upper and lower airways the level of inflammation and oxidative stress and to investigate the relationship between biomarkers in persistent allergic rhinitis (PER) and in concomitant asthma with PER. By a crosssectional study we measured oral and nasal (FENO) and oral and nasal EBC 8-isoprostane, LTB4 and PGE2 in children with PER (n=14) and with PER and concomitant intermittent asthma (IA; n=25), mild persistent asthma (mA; n=28), moderate persistent asthma (MA; n=13) and in Healthy Controls (HCs; n=13). Oral…

exhaled breath condensateMaleAllergypersistent allergic rhinitisMucous membrane of noseairway inflammationFENO; LTB4; persistent allergic rhinitisGastroenterologyprostaglandinsleukotrienesImmunology and AllergyExhaled breath condensateChildMouth Mucosa; Humans; Asthma; Child; Inflammation; Nitric Oxide; Cross-Sectional Studies; Dinoprostone; Leukotriene B4; Rhinitis Allergic Perennial; Oxidative Stress; Nasal Mucosa; Adolescent; Breath Tests; Female; MaleSettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICABreath TestsAnesthesiaLTB4FemaleFENOmedicine.symptomHumanBreath Testmedicine.medical_specialtyRhinitis Allergic PerennialSettore BIO/14 - FARMACOLOGIAAdolescentImmunologyInflammationNitric OxideLeukotriene B4DinoprostoneInternal medicineisoprostanesmedicineHumansAsthmaCross-Sectional StudieInflammationPharmacologybusiness.industryMouth MucosaOxidative Streallergymedicine.diseaseAsthmarespiratory tract diseasesNasal MucosaOxidative StressCross-Sectional StudiesConcomitantExhaled nitric oxideexhaled nitric oxidebusinessAirwaypediatric asthmaInternational Journal of Immunopathology and Pharmacology
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Allergic sensitization to common pets (cats/dogs) according to different possible modalities of exposure: an Italian Multicenter Study

2018

Abstract Background The query “are there animals at home?” is usually administered for collecting information on anamnesis. This modality to consider exposure to pet allergens constitutes a potential bias in epidemiological studies and in clinical practice. The aim of our study was to evaluate/quantify different modalities of exposure to cat/dog in inducing allergic sensitization. Methods Thirty Italian Allergy units participated in this study. Each centre was required to collect the data of at least 20 consecutive outpatients sensitized to cat/dog allergens. A standardized form reported all demographic data and a particular attention was paid in relieving possible modalities of exposure to…

lcsh:Immunologic diseases. AllergyAllergymedicine.medical_specialtyImmunologySettore MED/10 - Malattie Dell'Apparato RespiratorioPets exposureAllergic rhinitisAllergic sensitization03 medical and health sciences0302 clinical medicineInternal medicineEpidemiologyAllergic rhinitiDogHypersensitivitymedicineImmunology and Allergy030212 general & internal medicineAllergic rhinitis Allergic sensitization Bronchial asthma Cat; Dog Hypersensitivity Pets Pets exposure Immunology and Allergy Immunology Molecular BiologyBronchial asthmaMolecular BiologyAllergic rhinitis; Allergic sensitization; Bronchial asthma; Cat; Dog; Hypersensitivity; Pets; Pets exposureAllergic sensitizationAnamnesisCATSModalitiesbusiness.industryResearchCatPetsmedicine.diseasePet ownershipPet030228 respiratory systemMulticenter studyAllergic rhinitis; Allergic sensitization; Bronchial asthma; Cat; Dog; Hypersensitivity; Pets; Pets exposure; Immunology and Allergy; Immunology; Molecular Biologylcsh:RC581-607businessClinical and Molecular Allergy
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Catching allergy by a simple questionnaire

2014

Background Identifying allergic rhinitis requires allergy testing, but the first-line referral for rhinitis are usually primary care physicians (PCP), who are not familiar with such tests. The availability of easy and simple tests to be used by PCP to suggest allergy should be very useful. Methods The Respiratory Allergy Prediction (RAP) test, based on 9 questions and previously validated by a panel of experts, was evaluated in this study. Results An overall number of 401 patients (48.6% males, age range 14–62 years) with respiratory symptoms was included. Of them, 89 (22.2%) showed negative results to SPT, while 312 (77.8%) had at least one positive result to SPT. Cohen’s kappa coefficient…

lcsh:Immunologic diseases. AllergyPulmonary and Respiratory MedicinePediatricsmedicine.medical_specialtyAllergyReferralAllergymedicine.medical_treatmentImmunologyAllergy testingPrimary careAllergy testingSettore MED/10 - Malattie Dell'Apparato RespiratorioPharmacistsAllergic rhinitisCohen's kappaAllergic rhinitimedicineImmunology and AllergyOriginal Researchbusiness.industrymedicine.diseaseAllergic rhinitis; Allergy; Allergy testing; Pharmacists; Primary care physicians; Immunology and AllergyTest (assessment)Primary care physicianNasal sprayPharmacistPrimary care physiciansAllergistslcsh:RC581-607business
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Efficacy of subcutaneous and sublingual immunotherapy with grass allergens for seasonal allergic rhinitis: a meta-analysis–based comparison

2012

Background: Subcutaneous (SCIT) and sublingual (SLIT) immunotherapy are the 2 most prescribed routes for administering allergen-specific immunotherapy. They were shown to be effective in control of symptoms and in reducing rescue medication use in patients with allergic diseases, but their effectiveness has to be balanced against side effects. In recent years, SLIT has been increasingly prescribed, instead of SCIT, because of improved safety and easy administration. Objective: We assessed which route is the most effective in the treatment of patients with seasonal allergic rhinitis to grass pollen. Methods: An indirect meta-analysis–based comparison between SCIT and SLIT was performed. Trea…

medicine.medical_specialtybusiness.industrymedicine.medical_treatmentImmunologySublingual immunotherapy subcutaneous immunotherapy allergic rhinitis grass meta-analysisPlaceboSlitlaw.inventionSettore MED/01 - Statistica MedicaRandomized controlled trialStrictly standardized mean differencelawMeta-analysisInternal medicineImmunologymedicineImmunology and AllergySublingual immunotherapybusinessAdverse effectDesensitization (medicine)
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Molekulārās sensibilizācijas profila pret suņiem saistība ar astmas un alerģiska rinīta kontroles rādītājiem

2022

Izpētes objekts Šis pētījums tika veikts, lai novērtētu suņa alergēnu molekulu sensitizāciju saistību ar astmu un alerģisko rinītu. Pētījuma metodoloģija Tika analizēti dati pacientiem, kuriem veikta ALEX vai ALEX2 paneļa testēšana un iegūts sensitizāciju profils katrai suņa alergēna molekulai (Can f 1, Can f 2, Can f 3, Can f 4, Can f 5 un Can f 6). Iegūtie dati tika analizēti kopā ar pacienta datiem par astmu un alerģisko rinītu. Rezultāti Molekulārā sensitizācija pret Can f 1, Can f 2 un Can f 6 uzrādīja statistiski nozīmīgu ietekmi uz astmas risku, taču, kad tika izslēgta sensitizācija pret citu dzīvnieku epitēliju, tikai Can f 1 un Can f 2 uzrādīja statistiski nozīmīgu ietekmi. Arī poz…

molecular testingallergic rhinitisdog allergen moleculesALEXasthmaMedicīna
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