Search results for "AMA"
showing 10 items of 8558 documents
Effects of Infrared-A Irradiation on Skin: Discrepancies in Published Data Highlight the Need for an Exact Consideration of Physical and Photobiologi…
2010
Skin exposure to infrared (IR) radiation should be limited in terms of irradiance, exposure time and frequency in order to avoid acute or chronic damage. Recommendations aimed at protecting humans from the risks of skin exposure to IR (e.g. ICNIRP, ACGIH) are only defined in terms of acute effects (e.g. heat pain and cardiovascular collapse), whereas the actual exposure conditions (e.g. spectral distribution, exposure geometry, frequency and number of exposures, thermal exchange with the environment, metabolic energy production and regulatory responses) are not taken into consideration. Since the IR component of solar radiation reaching the Earth's surface is mainly IR-A, and considering th…
Resistance Training Acutely Impairs Agility and Spike-Specific Performance Measures in Collegiate Female Volleyball Players Returning from the Off-Se…
2020
This study examined the acute effects of resistance training (RT) on volleyball-specific performance. Sixteen female volleyball players undertook their initial, pre-season RT bout. Countermovement jump (CMJ), delayed onset of muscle soreness (DOMS), and sport-specific performances (i.e., run-up jump, agility, and spiking speed and accuracy) were measured before, 24 (T24), and 48 (T48) hours after RT. A significant increase in DOMS was observed at T24 and T48 (~207.6% ±
Case study : curriculum access accommodations in preschool student with cerebral palsy
2012
Se presenta el contenido de una intervención con un alumno de educación infantil afectado de parálisis cerebral. La intervención se basa en una adaptación de acceso al currículum consistente en el diseño de tareas y actividades educativas con soporte informático accesible al alumno y adecuadas al nivel curricular propio para su edad y curso académico. Esta metodología garantiza al alumno un acceso al currículum minimizando los efectos de sus problemas de movilidad.
Lo stadio di Wimbledon: per una teoria dell'adattamento
2013
Se "Lo stadio di Wimbledon" (1983) di Daniele Del Giudice nasce soprattutto come meditazione sulla vocazione creativa, sono certamente le suggestioni sulla scrittura a imporlo all’attenzione della critica. Del Giudice, che ha ribadito più volte nella sua opera la centralità dell’immaginario cinematografico, non ha certamente mai creduto alla presunta “inadattabilità” del suo romanzo: l’incontro con l’attore e regista francese Mathieu Amalric, che ha portato alla realizzazione del film "Le stade de Wimbledon" (2001), è stata un’occasione propizia per ulteriori riflessioni sull’adattamento. Ma è tornando alla pagina scritta che si trova l’intuizione più importante, ben nascosta nella trama de…
Is lithium implicated in tobacco addiction?
2016
IntroductionTobacco is a source of mineral elements that can affect human health in various ways, such as lithium, which is used as a psychiatric medication. Lithium salts are used as mood-stabilizing drugs and indicated in the treatment of manic-depressive psychosis.ObjectiveStudying the lithium content in tobacco over the smokers’plasma content and evaluate the potential role of lithium in tobacco addiction.MethodsA total of 18 different tobacco products (cigarettes, smokeless and water pipe tobacco) and 125 plasma samples (45 from smokers, 10 from ex-smokers and 70 from non-smokers) were collected to determinate the lithium content. Tobacco samples were digested with nitric acid and lith…
CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death
2011
Abstract Extracellular adenosine (ADO), generated from ATP or ADP through the concerted action of the ectoenzymes CD39 and CD73, elicits autocrine and paracrine effects mediated by type 1 purinergic receptors. We have tested whether the expression of CD39 and CD73 by chronic lymphocytic leukemia (CLL) cells activates an adenosinergic axis affecting growth and survival. By immunohistochemistry, CD39 is widely expressed in CLL lymph nodes, whereas CD73 is restricted to proliferation centers. CD73 expression is highest on Ki-67+ CLL cells, adjacent to T lymphocytes, and is further localized to perivascular areas. CD39+/CD73+ CLL cells generate ADO from ADP in a time- and concentration-dependen…
N-Heterocyclic Carbene Catalyzed [3+2] Cycloaddition of Enals with Masked Cinnamates for the Asymmetric One-Pot Synthesis of Adipic Acid Derivatives.
2017
A novel short entry to 3,4-disubstituted adipic acids has been developed by employing an asymmetric NHC-catalyzed [3+2] cycloaddition of enals with masked cinnammates in moderate to good yields and high stereoselectivities. The synthetic utility of the protocol was demonstrated by the basic conversion of the masked cyclopentanone intermediates to 3S,4S-disubstituted adipic acid precursors of pharmaceutically important gababutins.
Una ciencia admirable: filosofía y admiración en Descartes
2021
RESUMEN Aunque Descartes pretende hablar de cuestiones morales en general, y de las pasiones en particular, como si nadie hubiera escrito antes sobre ellas, lo cierto es que, en el caso de la admiración, es clara su referencia al mundo antiguo. En concreto, en este caso el pensador francés se sitúa críticamente en contra de la postura aristotélica, que entiende la admiración como el inicio de la filosofía. Frente a la propuesta clásica, que convierte dicha emoción en el motor permanente de la investigación de las primeras causas, para Descartes la curiosidad excesiva y el estupor del asombro son rechazables. No obstante, algunos han señalado el carácter ambivalente de las declaraciones cart…
Physical activity and aerobic fitness in relation to local and interhemispheric functional connectivity in adolescents' brains
2021
Abstract Introduction Adolescents have experienced decreased aerobic fitness levels and insufficient physical activity levels over the past decades. While both physical activity and aerobic fitness are related to physical and mental health, little is known concerning how they manifest in the brain during this stage of development, characterized by significant physical and psychosocial changes. The aim of the study is to examine the associations between both physical activity and aerobic fitness with brains’ functional connectivity. Methods Here, we examined how physical activity and aerobic fitness are associated with local and interhemispheric functional connectivity of the adolescent brai…
Pooled analysis of prospective European studies assessing the impact of using the 21-gene Recurrence Score assay on clinical decision making in women…
2016
PURPOSE: The 21-gene Recurrence Score assay (Oncotype DX) provides prognostic/predictive information in oestrogen receptor positive (ER+) early breast cancer, but access/reimbursement has been limited in most European countries in the absence of prospective outcome data. Recently, two large prospective studies and a real-life 5-year outcome study have been reported. We performed a pooled analysis of prospective European impact studies to generate robust data on impact of use in different clinical subgroups. METHODS: The analysis included four studies (French, German, Spanish, and British) in ER+ human epidermal growth factor receptor 2-negative breast cancer patients (n = 527). Node-positiv…