Search results for "AML"
showing 10 items of 184 documents
GAMLSS for Big Data: Roc Curve prediction using Twitter data
2017
During last years, Big Data appears as one of the most innovative and growing scientific area of interest. In this field, finding reliable methods to make accurate predictions represents one of the most inspirational challenges. The way to make prediction in the following paper is the use of ROC (Receiver Operating Characteristic) Curve, a binary prediction tool, often used for medical tests. The attention is focused in particular on the implementation of ROC Curve in GAMLSS (Generalized Additive Models for Location Scale and Shape), semi-parametric models suitable for huge and flexible dataset. An application will be shown where the class of GAMLSS is applied to Twitter data in order to pr…
Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mous…
2013
The t(8;21) chromosomal translocation activates aberrant expression of the AML1-ETO (AE) fusion protein and is commonly associated with core binding factor acute myeloid leukaemia (CBF AML). Combining a conditional mouse model that closely resembles the slow evolution and the mosaic AE expression pattern of human t(8;21) CBF AML with global transcriptome sequencing, we find that disease progression was characterized by two principal pathogenic mechanisms. Initially, AE expression modified the lineage potential of haematopoietic stem cells (HSCs), resulting in the selective expansion of the myeloid compartment at the expense of normal erythro- and lymphopoiesis. This lineage skewing was foll…
New insights for materials science characterisation using different complementary techniques combined with X-ray absorption Spectroscopy
2005
The combination of x-ray absorption spectroscopy (XAS) with UV-Vis and Raman spectroscopies or with Differential Scanning Calorimetry (DSC) has been recently carried out on the D44 beamline of DCI-LURE. The different set-ups used to perform such combinations are described and examples of combined investigations belonging to different field of materials science (coordination chemistry, sol-gel and catalysis) are presented.
Crítica Práctica de la Literatura Inglesa: Actividad formativa sobre Hamlet de Franco Zeffirelli (35334)
2016
Modelo de actividad formativa y evaluable de la asignatura Crítica Práctica de la Literatura Inglesa del Grado de Estudios Ingleses.
Centile estimation for a proportion response variable.
2015
This paper introduces two general models for computing centiles when the response variable Y can take values between 0 and 1, inclusive of 0 or 1. The models developed are more flexible alternatives to the beta inflated distribution. The first proposed model employs a flexible four parameter logit skew Student t (logitSST) distribution to model the response variable Y on the unit interval (0, 1), excluding 0 and 1. This model is then extended to the inflated logitSST distribution for Y on the unit interval, including 1. The second model developed in this paper is a generalised Tobit model for Y on the unit interval, including 1. Applying these two models to (1-Y) rather than Y enables model…
Samarbeid i hjertestansteam : en kvalitativ studie om intensivsyke- pleieres erfaringer fra samarbeid i hjertestansteam under resuscitering
2014
Masteroppgave i spesialsykepleie – Universitetet i Agder 2014 Project backround: Several areas in health care have recently seen an increased focus on the importance of cooperation. In its guidelines from 2010, The American Heart Association (AHA) places increased importance on non-technical skills in the training of personnel who perform advanced cardiac life support (ACLS). The Better And Systematic Team Foundation (BEST), have in recent years contributed to a growing focus on cooperation in trauma teams. However, in Norway, there is little research directly linked to the issue of cooperation in Norwegian cardiac arrest teams. Aim:The aim of this study is to gain knowledge about the exper…
Crítica Práctica de la Literatura Inglesa: Midterm Exam (35334)
2016
Modelo de examen parcial de la asignatura Crítica Práctica de la Literatura Inglesa del Grado de Estudio Ingleses en el curso 2015-16
Removal of molecular contamination in low-energy RIBs by the isolation-dissociation-isolation method
2020
Nuclear instruments & methods in physics research / B 463, 324 - 326 (2020). doi:10.1016/j.nimb.2019.04.072
Separation of atomic and molecular ions by ion mobility with an RF carpet
2021
Gas-filled stopping cells are used at accelerator laboratories for the thermalization of high-energy radioactive ion beams. Common challenges of many stopping cells are a high molecular background of extracted ions and limitations of extraction efficiency due to space-charge effects. At the FRS Ion Catcher at GSI, a new technique for removal of ionized molecules prior to their extraction out of the stopping cell has been developed. This technique utilizes the RF carpet for the separation of atomic ions from molecular contaminant ions through their difference in ion mobility. Results from the successful implementation and test during an experiment with a 600~MeV/u $^{124}$Xe primary beam are…
Theatrical Self-Reflexivity in Gregory Doran's Hamlet (2009)
2016
Este articulo tratara sobre la meta-teatralidad en la pelicula Hamlet de Gregory Doran (2009). Esta pelicula esta basada en una produccion escenica de la Royal Shakespeare Company presentada en el Courtyard Theatre (Stratford-upon-Avon) y el Novello Theatre (Londres). Contra los permanentes prejuicios que critican la fusion entre la puesta teatral y la pequena pantalla, Doran y el equipo creativo de Illuminations Media optan por sacar partido de las naturalezas opuestas de las artes teatrales y cinematograficas. Los resultados de esta decision creativa se manifiestan en forma de representacion hibrida para television. La pelicula se ha rodado en un espacio acondicionado con el proposito de …