Search results for "ANESTHESIA"
showing 10 items of 2277 documents
Current state of critically ill patients sedation with volatile anesthetics. Its role in renal and hepatic toxicity
2013
Summary The anesthetic-conserving device (AnaConDa™) facilitated, from a technical viewpoint, the routine use of volatile anesthetics in intensive care patients using ICU ventilators. To date, its use is currently time-limited by clinicians due to the potential renal and hepatic toxicity associated with the production of plasma fluoride after its metabolism, despite its advantages. We reviewed the available human and animal studies literature examining the use of volatile anesthetics as sedative agents and its role in renal and/or hepatic toxicity. We have very few studies concerning the prolonged administration of sevoflurane through the AnaConDa™ and its effect on renal and hepatic functi…
ESRA19-0239 Surgical treatment of femoral and knee injuries under peripheral regional anaesthesia: a case series
2019
Background and aims Neuroaxial anaesthesia is gold standard for lower extremity surgeries. Nowadays the introduction of ultrasound guided peripheral nerves blocks (PBN) changed the approach to orthopaedic surgery. Methods This case series evaluates postoperative pain in 17 patients with femoral or knee fractures who received PNB because of contraindications to subarachnoid anaesthesia (eg. anticoagulation therapies, refusal). We performed femoral nerve block (levobupivacaine 0,5% 15 ml), obturators nerve block (levobupivacaine 0,5% 7 ml), lateral cutaneous nerve block (levobupivacaine 0.5% 3 ml) and sciatic nerve block (levobupivacaine 0,5% 20 ml) focusing on a lateral approach according to…
Franz Kuhn, his contribution to anaesthesia and emergency medicine.
2001
Franz Kuhn (1866-1929), a German surgeon, made a significant practical and scientific contribution towards the development of modern anaesthesia and emergency medicine. He developed modern, scientifically based concepts in close correlation to practical inventions for every day use. All of his studies and developments were patient orientated and led to remarkable improvements in patient safety. Kuhn was a major protagonist of endotracheal intubation, perfected his flexo-metallic endotracheal tubes, worked on different techniques of intubating the trachea, applied positive pressure to the lungs during thoracic surgery and developed anaesthesia machines. In the early 20th century, he wrote se…
Comparison of Standard Cardiopulmonary Resuscitation Versus the Combination of Active Compression-Decompression Cardiopulmonary Resuscitation and an …
2003
Background— Active compression-decompression (ACD) CPR combined with an inspiratory impedance threshold device (ITD) improves vital organ blood flow during cardiac arrest. This study compared survival rates with ACD+ITD CPR versus standard manual CPR (S-CPR). Methods and Results— A prospective, controlled trial was performed in Mainz, Germany, in which a 2-tiered emergency response included early defibrillation. Patients with out-of-hospital arrest of presumed cardiac pathogenesis were sequentially randomized to ACD+ITD CPR or S-CPR by the advanced life support team after intubation. Rescuers learned which method of CPR to use at the start of each work shift. The primary end point was 1-ho…
A clinical study of the effect of calcium sodium phosphosilicate on dentin hypersensitivity
2012
Objective: Dentinal hypersensitivity is a commonly encountered problem with varied treatment options for its management. A large number of home use products have been tested and used for the management of dentinal hypersensitivity. This 8 week clinical trial investigates the temporal efficacy of commercially available calcium sodium phosphosilicate containing toothpaste in comparison to a potassium nitrate containing toothpaste. Methods: A total 20 subjects between the ages of 18 to 65 years were screened for a visual analogue score (VAS) for sensitivity of 5 or more by testing with a cold stimulus and randomly divided into test and positive control groups. Baseline sensitivity VAS scores t…
Cerebral Autoregulation in Non-Brain Injured Patients: A Systematic Review.
2021
Introduction: Cerebral autoregulation (CA) plays a fundamental role in the maintenance of adequate cerebral blood flow (CBF). CA monitoring, through direct and indirect techniques, may guide an appropriate therapeutic approach aimed at improving CBF and reducing neurological complications; so far, the role of CA has been investigated mainly in brain-injured patients. The aim of this study is to investigate the role of CA in non-brain injured patients.Methods: A systematic consultation of literature was carried out. Search terms included: “CA and sepsis,” “CA and surgery,” and “CA and non-brain injury.”Results: Our research individualized 294 studies and after screening, 22 studies were anal…
Combined Epidural and General Anesthesia Prevents Excessive Oxygen Consumption Postoperatively
1994
In the postoperative period patients are at risk of excessive oxygen consumption (VO2). However, patients suffering from cardiovascular disease may be unable to increase their oxygen transport capacity sufficiently and may be especially vulnerable to tissue hypoxia as part of the reaction to intraoperative stress. During the last 10 years contradictory results concerning the benefits of a combined epidural and light general anesthesia have been published. Some of the results indicate that postoperative catabolism maybe depressed and that the neuroendocrine response to stress may be inhibited by such a combined technique1,2. We studied the effect of a combined epidural and light general anes…
Interventional treatment for neuropathic pain due to combined cervical radiculopathy and carpal tunnel syndrome: a case report
2017
Key Clinical Message The coexistence of median and cervical nerve root damage might hide a complex pathophysiology. Here, we describe and discuss the case of a patient suffering from numbness and painful tingling of the hand, whose symptoms were effectively treated with pulsed radiofrequency and epidural administration of bupivacaine and morphine.
Myogenic effects enhance norepinephrine constriction: Inhibition by nitric oxide and felodipine
1998
Myogenic effects enhance norepinephrine constriction: Inhibition by nitric oxide and felodipine. Myogenic, pressure-induced vasoconstriction may amplify the effects of circulating vasoconstrictors. Through intravital microscopy in cremaster arterioles (31 to 115 μm diameter), the relative contribution of myogenic responses (MR) to norepinephrine (NE)-induced constriction and the inhibitor potency of nitric oxide (NO) or a Ca2+ entry blocker (CEB), felodipine (F), were examined. In 24 anesthetized hamsters, a vessel occluder was placed around the aorta to control cremaster vessel inflow pressure (IP). NE infusion increased blood pressure (by 50 ± 2mm Hg) and induced significant constriction …
Brimonidine versus dapiprazole: Influence on pupil size at various illumination levels.
2005
To evaluate the influence of dapiprazole versus brimonidine on pupil size at various illumination levels.Department of Ophthalmology, Johannes Gutenberg-University, Mainz, Germany.In randomized prospective study, 19 healthy volunteers received 2 ophthalmic solutions, dapiprazole and brimonidine, 1 in each eye, for intraindividual comparison. Before and after application, pupil diameter was measured using an infrared binocular pupillometer at 3 illumination levels (0.03, 0.82, and 6.4 lux).Only slight pupil dilation was observed under scotopic conditions after application of both agents. After 20 minutes, the median reduction in pupil width was 1.4 mm for brimonidine and 0.9 mm for dapiprazo…