Search results for "ANP"
showing 10 items of 314 documents
Human umbilical cord expresses several vasoactive peptides involved in the local regulation of vascular tone: protein and gene expression of Orphanin…
2011
Full-term human umbilical cord contains three blood vessels: two arteries coiled around a vein and surrounded by Wharton’s jelly, a mucous tissue with few mesenchymal stromal cells and abundant extracellular matrix. Umbilical vessels lack innervations, thus endothelial cells must play a role in the control of blood flow. The aim of this study was to investigate in human umbilical cord the expression of five peptides that could be involved in the regulation of vascular tone: Orphanin FQ, Oxytocin, Atrial Natriuretic Peptide (ANP), endothelial Nitric Oxide Synthase (eNOS) and inducible Nitric Oxide Synthase (iNOS). The expression of these molecules in full-term human umbilical cord …
ANP differentiates between primary Submandibular Gland Squamous Cell Carcinoma and Oral Squamous Cell Carcinoma: Preliminary data
2021
The natriuretic peptide system consists of three ligands, Atrial Natriuretic Peptide (ANP), Brain Natriuretic peptide (BNP) and C-type Natriuretic peptide (CNP), and three natriuretic peptide receptors (NPR’s), NPRA, NPRB and NPRC. We investigated the expression levels of NPPA (encoding ANP) and NPR1 (encoding NPRA, the main receptor for ANP) in primary benign (pleomorphic adenoma) and malignant (squamous cell carcinoma, SCC) submandibular salivary gland (SMG) tumors, as well as in primary oral squamous cell carcinoma (OSCC). We found that the NPPA and NPR1 expression levels were significantly different in SMG SCC versus OSCC, exhibiting a significant increase in NPPA and absence of NPR1 ex…
Atrial natriuretic peptide (ANP) and oxytocin-expression in the adult rat and mouse cerebellum.
2015
Abstract Background: Many studies are in the literature on the ANP and oxytocin-presence in the brain, but very few studies with controversial results are reported on the presence of these peptides in the cerebellum. This immunohistochemical study investigates on the ANP and oxytocin-presence in the cerebellum of the adult rat and mouse rodents. Results: This study, firstly, evidences the ANP- immunopositivity in cerebellar cortex of both rat and mouse rodents. In rat the molecular layer presents some few immunopositive fibers, but no neuron resulted immunopositive; the granular and Purkinje cells are immunopositive. In mouse the cerebellar cortex ANP-immunopositivity is present in all laye…
Porphyrin tributyltin(IV) complexes for a novel approach in the tratment of human melanoma
2012
Melanoma is the most deadly form of skin cancer, largely refractory to existing therapies. The study of porphyrin derivatives as potential anti-tumor drugs has been an interesting field of investigation in the last years. Recently, a photo-independent cytotoxic effect of (Bu3Sn)4TPPS in the blocking melanoma cell proliferation an inducing a morphology cell change was investigated.[1] Amphiphilic CD (ACyD) provides more water soluble and adaptable nanovectors through modulation of the balance between hydrophobic and hydrophilic chains at both CD sides. ACyD can be conveniently tailored by covalently appending fluorescent label or receptor-targeting glycosyl- groups and can encapsulate conven…
RENAL SALT WASTING: UNA SINDROME DA INAPPROPRIATA SECREZIONE DI URODILATINA? UNO STUDIO PILOTA
2022
La Renal Salt Wasting Syndrome (RSW) è una sindrome clinica con caratteristiche di laboratorio che si sovrappongono completamente alla sindrome da secrezione inappropriata di ADH (SIADH). La differenza fondamentale tra le due sindromi risiede nel volume extracellulare (ECV), ridotto nella RSW e normale o leggermente aumentato nella SIADH. Le difficoltà nella diagnosi differenziale di questa sindrome e nella comprensione del preciso meccanismo patogenetico hanno contribuito a mettere in discussione l'esistenza stessa di RSW. Considerando le caratteristiche della RSW, è stato studiato il possibile ruolo dei peptidi natriuretici per spiegare la sua patogenesi come ANP e BNP, con risultati inso…
Henkilönnimistä suomalaisessa kirjallisuudessa : tarkastelussa Sillanpään, Waltarin ja Joenpellon teokset
2000
Student engagement in two Singaporean secondary schools
2016
Student engagement is important to prevent school dropout and enhance school experiences. Engagement of secondary 2 and 3 students in Singapore was studied with Student Engagement Instrument (SEI) and its relation to burnout. The SEI measured students’ cognitive and affective engagement while burnout was examined using School Burnout Inventory (SBI). An electronic survey was administered to 335 students from two secondary schools. The engagement and burnout across grades, streams, gender, academic achievements and family background were studied. Evidence showed lower engagement for secondary three than two students, while ethnicity had a major impact on engagement level, with minority ethni…
Parents' work burnout and adolescents' school burnout: Are they shared?
2011
There is considerable evidence that psychological distress not only has consequences for those who experience it but also can create problems for other members of the distressed person's family. To examine whether parents' work burnout and their children's school burnout are shared in the family, 515 adolescents (median age = 15) completed scales for school burnout and 595 of their parents (342 mothers, 253 fathers) completed scales for work burnout and their economic situation. The intraclass correlations showed that parents' work burnout and adolescents' school burnout was shared in the family. In addition, the better the economic situation the parents' experienced, the lower was the leve…
Do social comparison and coping styles play a role in the development of burnout? Cross-sectional and longitudinal findings
2006
The present longitudinal research among 558 teachers focused on the role of upward comparisons (with others performing better), downward comparisons (with others performing worse), and coping styles in relation to burnout. Assessed were identification (recognizing oneself in the other) and contrast (seeing the other as a competitor) in upward and downward comparison. Cross-sectionally, downward identification and upward contrast were positively related to burnout and negatively related to a direct coping style, whereas upward identification was negatively related to burnout and positively related to a direct coping style. Downward identification was positively related to a palliative coping…