Search results for "APES"
showing 10 items of 261 documents
PI-Extension of porphyrins via intramolecular aromatic oxidative C-N coupling
2019
Π-extension of porphyrins has been performed via intramolecular oxidative C-N coupling of peripheral pyridinyl fragment(s) with the porphyrin core. These fusion reactions lead to the formation of C-N bond(s) between the substituent(s) and the porphyrin. The precursors were functionnalized with 2-mercaptopyridine, 8-hydoxyquinoline and 2-picoline at their meso or β-pyrrolic positions via aromatic nucleophlic substitution, cross-coupling reaction or reaction of the macrocycle with organolithium reagents. Voltametric analyses revealed some marked differences on the reactivity of the porphyrins depending on their substitution pattern and metalation (nickel(II) or zinc(II)). Chemical and electro…
Exploring the opportunities and challenges of european design policy to enable innovation. The case of designscapes project
2020
Design policy for innovation and prosperity has been acknowledged and adopted globally. Existing literature on design policy usually adopts a top-down perspective to analyse the components of the design innovation system and ignores the practical needs of practitioners. Our study aims to explore potential opportunities and challenges of design policies for design-enabled innovation from a bottom-up perspective. We firstly discussed the enabling role of design in the context of design as input, output and process of innovation with emphasis on design-enabled innovation conception
Evolutionary plasticity of SH3 domain binding by Nef proteins of the HIV-1/SIVcpz lentiviral lineage
2021
The accessory protein Nef of human and simian immunodeficiency viruses (HIV and SIV) is an important pathogenicity factor known to interact with cellular protein kinases and other signaling proteins. A canonical SH3 domain binding motif in Nef is required for most of these interactions. For example, HIV-1 Nef activates the tyrosine kinase Hck by tightly binding to its SH3 domain. An archetypal contact between a negatively charged SH3 residue and a highly conserved arginine in Nef (Arg77) plays a key role here. Combining structural analyses with functional assays, we here show that Nef proteins have also developed a distinct structural strategy—termed the "R-clamp”—that favors the formation …
Detection of lactobacillic acid in low erucic rapeseed oil--A note of caution when quantifying cyclic fatty acid monomers in vegetable oils.
2010
International audience; The purpose of this work was to identify an unknown component which has been detected during the analysis of cyclic fatty acid monomers (CFAMs) in low erucic acid rapeseed oils (LEAR). A sample of crude LEAR was transformed into fatty acid methyl esters (FAMEs) and hydrogenated using PtO2. The hydrogenated sample was fractionated by reversed-phase high-performance liquid chromatography (RP-HPLC) and the fraction containing the CFAMs transformed into picolinyl esters. Analysing these picolinyl derivatives by gas-liquid chromatography coupled to mass spectrometry (GC-MS) showed that the unknown product observed in LEAR is the 11,12-methylene-octadecanoic acid. This cyc…
Pulsed Electric Fields and High-Voltage Electrical Discharges-Assisted Extraction of Valuable Biocompounds and Biopolymers from Rapeseed By-Products
2017
Cartografia: relleu
2020
El document forma part dels materials docents programats mitjançant l'ajut del Servei de Política Lingüística de la Universitat de València Com representar el relleu als mapes Map topography
Vivere ai margini. Comunità rom tra i borderscapes
2016
Il presente saggio presenta una sintesi della ricerca etnografica condotta a Palermo, presso il campo rom, dal 2005 al 2010 (Di Giovanni 2015). Il focus d’indagine prescelto è quello di mettere in luce le pratiche di attraversamento fisico-metaforico degli spazi urbani, adottate da alcune famiglie rom nel loro quotidiano fatto di invisibilità e di discriminazione. A partire dagli studi condotti da Leonardo Piasere (1991, 1996, 1999, 2004) e da Nando Sigona (2002, 2005, 2009); la ricerca prova a delineare la molteplice fisionomia di questa minoranza etnica nella città di Palermo nel riorganizzare e condurre un’esistenza ai margini della città, con un riferimento comparativo all’Italia e all’…
Of Oaks, Erratic Boulders, and Milkmaids
2004
In the study and care for rural landscapes and their inhabitants a perpetual dilemma is knowing the different discourses those landscapes embody for a culture group, or “discourse community,” as Siri Aasbo (1999: 148) calls it (after Eco 1977). It is a well-known truism that a gap exists in the understanding and evaluation of landscapes between insiders and outsiders, natives and visitors, actors and observers, inhabitants and experts. Since this is known territory, I shall not revisit it, except to restate the obvious — expert opinion, even when well-intended, rarely agrees with the local inhabitants in what is good for them. As Sverker Sorlin expresses it, landscape is a “contested terrai…
High-Resolution Photoacoustic Raman-Spectroscopy of Gases
1992
0377-0486; A high-resolution photoacoustic Raman spectroscopy experiment is described. The resolution achieved by using two single-mode pulsed lasers is about 0.0054 cm-1 (full width at half maximum intensity). The experiment was tested first on the v1/2v2 bands of CO2 and gave an increase of at least about one order of magnitude in the signal-to-noise ratio with respect to stimulated Raman spectroscopy at low pressure (ca. 10 Torr almost-equal-to 13 kPa). The sensitivity is also demonstrated by the study of the weak hot band v1 + v2 - v2 of CO2. In both cases, the experimental line shape is well reproduced by taking into account Doppler and collisional effects. A comparison with CARS spect…
Determination of Temperature by Stimulated Raman Scattering of Molecular Nitrogen, Oxygen, and Carbon-Dioxide
1993
0721-7269; We have determined the temperature from SRS spectra of N2-N2, N2-CO2, O2-O2, and CO2-CO2 recorded in wide pressure and temperature ranges. The fitting procedure takes simultaneously into account the Dicke effect and motional narrowing. We have quantified the accuracy of the MEG and ECS-P models for rotational relaxation. The temperature extracted from each model is compared with thermocouple measurements. The influence of vibrational broadening and shifting is discussed in detail.