Search results for "APR"
showing 10 items of 2648 documents
Quality control of pharmaceuticals containing non-steroidal anti-inflammatory drugs by micellar liquid chromatography
2002
A liquid chromatographic procedure is described for the determination of acemetacin, diclofenac, indomethacin, ketoprofen, nabumetone, naproxen, piketoprofen, and tolmentin in pharmaceutical preparations. The compounds were separated on a Kromasil C18 analytical column, with a guard column of similar characteristics; the mobile phase was 0.06 M cetyltrimethylammonium bromide, at pH 7, containing 10% 1-butanol. At a flow rate of 1 mL min−1 the elution time of the most retained compound was 23 min. Limits of detection were between 0.01 μ g mL−1 for diclofenac and 0.2 μ g mL−1 for naproxen. The proposed method enables the determination of non-steroidal anti-inflammatory drugs in pharmaceutical…
Distinguishing the roles of carrier and biofilm in filtering media for the removal of pharmaceutical compounds from wastewater
2017
Abstract Pharmaceutical compounds (PCs) represent a large group of micropollutants in wastewaters (WW) worldwide. Many PCs are resistant to conventional WW treatment. Moreover, for some PCs the removal process is reversible. The aim of this study was to test three newly developed ceramic carriers for biofilm formation and PCs removal. The testing of untreated WW samples by liquid chromatography coupled to Orbitrap mass spectrometry allowed to detect the occurrence of 18 PCs in the range from 26 ng/L to 20,688 ng/L, with the highest concentrations found for caffeine. Besides, among PCs with concentrations above 1,000 ng/L, ibuprofen (19,234 ng/L), naproxen (1,405 ng/L), xylazine (1,366 ng/L)…
Comparison between sodium dodecylsulphate and cetyltrimethylammonium bromide as mobile phases in the micellar liquid chromatography determination of …
2004
The retention behaviour of non-steroidal anti-inflammatory drugs (NSAIDs) using micellar mobile phases of sodium dodecylsulphate (SDS) is studied and compared with that observed with micellar mobile phases of cetyltrimethylammonium bromide (CTAB). A liquid chromatographic procedure for the determination of acemetacin, diclofenac, indomethacin, ketoprofen, naproxen and tolmetin in pharmaceutical preparations is described. The proposed system uses a Kromasil C18 analytical column and a solution of 0.15 M SDS at pH 3 with 10% 1-propanol as mobile phase. Under these conditions, the studied NSAIDs elute between 6 and 10 min at a 1 mL min(-1) flow rate. Limits of detection (LOD) are lower than 0.…
Near-Infrared, Light-Triggered, On-Demand Antiinflammatories and Antibiotics Release by Graphene Oxide/Elecrospun PCL Patch for Wound Healing
2019
Very recently, significant attention has been focused on the adsorption and cell adhesion properties of graphene oxide (GO), because it is expected to allow high drug loading and controlled drug release, as well as the promotion of cell adhesion and proliferation. This is particularly interesting in the promotion of wound healing, where antibiotics and anti-inflammatories should be locally released for a prolonged time to allow fibroblast proliferation. Here, we designed an implantable patch consisting of poly(caprolactone) electrospun covered with GO, henceforth named GO&ndash
Long-term evaluation of quinapril in mild to moderate hypertension: assessment of renal haemodynamics and function.
1995
Medicīna
2004
E-learning and development of key competencies: a bibliometric study
2021
El aprendizaje electrónico (e-learning) es una modalidad educativa que vertebra, a través de diferentes herramientas y metodologías, el aprendizaje mediado por las tecnologías. Este estudio pretende, a partir de esta idea, revisar el impacto del aprendizaje electrónico en el desarrollo de las competencias clave desde un punto de vista bibliométrico y de contenido. Para ello, se analiza la producción científica relativa a estudios donde esta modalidad está al servicio del desarrollo de estas competencias, reflexionando así sobre los beneficios de los entornos flexibles y abiertos. Concretamente, se han analizado 255 artículos disponibles en la base de datos Scopus, bajo el criterio temporal …
Intrapreneurs: Characteristics and Behavior
2017
Intrapreneurship has become a relevant topic in literature as far as its impact on organizational performance is more and more often highlighted from very diverse points of view. The main goal of this chapter is introducing the specific personal and professional profile of intrapreneurs, considered as highly committed individuals motivated by innovation, continuous improvement and able to leader teams in the direction they foresee within the companies in which they work. This chapter will present the relevance and impact of intrapreneurship, the role and main characteristics of the intrapreneurs, their behavior and motivations, and finally some good practices will be exposed in order to enc…
Malignā hipertermija: diagnostikas, ārstēšanas un profilakses sistēmas ieviešana Latvijā
2011
Elektroniskā versija nesatur pielikumus
Augšējo un apakšējo funkciju metodes pielietojums otrās kārtas robežproblēmu atrisināmības pētīšanā
2021
Darbā tiek izpētīta otrās kārtas periodiskā robežproblēma parastajam diferenciālvienādojumam un tās atrisināmība, izmantojot augšējo un apakšējo funkciju metodi. Tiek apskatīta periodiskā robežproblēma lineāram homogēnam vienādojumam un atbilstošam nehomogēnam vienādojumam un šie rezultāti tiek izmantoti kā palīgrezultāti turpmākajā pētījumā. Tiek aplūkota Konti teorēma, uz kuras pamata balstās bakalaura darba galveno rezultātu pierādījumi. Tiek demonstrēti piemēri, kuri ilustrē bakalaura darba galvenos rezultātus.