Search results for "APT"

The elite judo female athlete's heart.

2022

Purpose: There is a paucity of data on physiological heart adaptation in elite-level judo female athletes. This study aimed to assess left ventricular morphology and function in highly trained elite female judokas.Methods: The study prospectively included 18 females aged 23.5 ± 2.25 years, nine elite level judokas, and nine healthy non-athlete volunteers. All participants underwent a medical examination, electrocardiogram, and transthoracic 2D echocardiogram. Left ventricular diastolic and systolic diameters and volumes were determined, and parameters of left heart geometry and function (systolic and diastolic) were measured, calculated, and compared between groups.Results: When groups were…

Books and Letters in Joe Wright's Pride & Prejudice (2005): Anticipating the Spectator's Response through the Thematization of Film Adaptation

2007

International audience; About Books and letters in Pride & Prejudice.

Move the way you feel : effects of musical features, perceived emotions, and personality on music-induced movement

2013

Meeting the need for flexibility in business processes

2017

Nykyaikaisessa liiketoimintaympäristössä organisaatioiden tulee olla joustavia. Joustavuuden tarve ilmenee monella tavalla – organisaatioiden tulee pystyä sopeuttamaan sekä toimintansa luonnetta että toimintatapojaan, sekä tilapäisesti että pysyvästi, sekä ennakoitavissa että ennakoimattomissa tilanteissa. Liiketoimintaprosessisuuntautuneisuus ja Business Process Management (BPM) ovat viime aikoina olleet merkittäviä paradigmoja organisaatioiden johtamisessa ja saaneet tunnustusta keinoina parantaa organisaatioiden suorituskykyä. On kuitenkin epäselvyyttä siitä, kuinka yhteensopivia perinteiset BPM-metodit ovat joustavuuden vaatimusten kanssa. Tällä eksploratiivisella kirjallisuuskatsauksel…

Me, you and the dance : effects of individual differences and social context on music-induced movement

2018

To dance is usually to dance with someone else. Dance often takes place in social contexts such as a club or party, where individuals’ movements not only reflect their own traits and feelings but can the movements of others in many ways. The aim of this thesis is to study some of the factors that may affect music-induced movement in social contexts, particularly trait empathy. The thesis also aims to investigate the influence of inherently dyadic features, such as similarity between dance partners, and to explore how entrainment and interaction can be quantified in a free dance movement context using a variety of analytic approaches. A first analysis of individual dance data from 30 partici…

Musical aptitude and foreign language learning skills - neural and behavioral evidence about their connections

2009

Perceiving music and language seems to depend upon subtle and accurate auditory processing skills. Could music and language also share common neural resources? Possible interaction between music and speech memory systems has not been ruled out. On the contrary, there is increasing evidence pointing out the accuracy at perceiving phonetic contrasts in native or foreign language of subjects with musical aptitude or musical training. The main focus of this study was to examine the relationship between musical aptitude and linguistic abilities, especially in terms of second language pronunciation skills. We examined 10-12-year-old elementary school children’s ability to preattentively process m…

Mécanisme d’absorption intestinale des acides gras à longue chaîne : rôle émergent du CD36

2012

International audience; Excessive lipid intake, associated with a qualitative imbalance, favors the development of obesity and associated diseases. Among the organs involved in lipid homeostasis, the small intestine remains the most poorly known although it is responsible for the lipid bioavailability and largely contributes to the regulation of postprandial hypertriglyceridemia. The mechanism of long chain fatty acid (LCFA) intestinal absorption is not totally elucidated. The synthesis of recent literature indicates that the intestine is able to adapt its absorption capacity to the fat content of the diet. This adaptation takes place through a fat-coordinated induction of LBP and apolipopr…

Role of RNA Motifs in RNA Interaction with Membrane Lipid Rafts: Implications for Therapeutic Applications of Exosomal RNAs

2021

RNA motifs may promote interactions with exosomes (EXO-motifs) and lipid rafts (RAFT-motifs) that are enriched in exosomal membranes. These interactions can promote selective RNA loading into exosomes. We quantified the affinity between RNA aptamers containing various EXO- and RAFT-motifs and membrane lipid rafts in a liposome model of exosomes by determining the dissociation constants. Analysis of the secondary structure of RNA molecules provided data about the possible location of EXO- and RAFT-motifs within the RNA structure. The affinity of RNAs containing RAFT-motifs (UUGU, UCCC, CUCC, CCCU) and some EXO-motifs (CCCU, UCCU) to rafted liposomes is higher in comparison to aptamers withou…

Binding of RNA Aptamers to Membrane Lipid Rafts: Implications for Exosomal miRNAs Transfer from Cancer to Immune Cells

2020

Intraluminal vesicles (ILVs) are released into the extracellular space as exosomes after the fusion of multivesicular bodies (MVBs) with the plasma membrane. miRNAs are delivered to the raft-like region of MVB by RNA-binding proteins (RBPs). RNA loading into exosomes can be either through direct interaction between RNA and the raft-like region of the MVB membrane, or through interaction between an RBP&ndash

Selection of Membrane RNA Aptamers to Amyloid Beta Peptide: Implications for Exosome-Based Antioxidant Strategies

2019

The distribution of amyloid beta peptide 42 (Aβ42) between model exosomal membranes and a buffer solution was measured. The model membranes contained liquid-ordered regions or phosphatidylserine. Results demonstrated that up to ca. 20% of amyloid peptide, generated in the plasma (or intracellular) membrane as a result of proteolytic cleavage of amyloid precursor proteins by β- and γ-secretases, can stay within the membrane milieu. The selection of RNA aptamers that bind to Aβ42 incorporated into phosphatidylserine-containing liposomal membranes was performed using the selection-amplification (SELEX) method. After eight selection cycles, the pool of RNA aptamers was isol…