Search results for "APT"
showing 10 items of 5479 documents
Enhanced adhesion and in situ photothermal ablation of cancer cells in surface-functionalized electrospun microfiber scaffold with graphene oxide
2017
The physicochemical characteristics of a biomaterial surface highly affect the interaction with living cells. Recently, much attention has been focused on the adhesion properties of functional biomaterials toward cancer cells, since is expected to control metastatic spread of a tumor, which is related to good probability containing the progression of disease burden. Here, we designed an implantable poly(caprolactone)-based electrospun microfiber scaffold, henceforth PCLMF-GO, to simultaneously capture and kill cancer cells by tuning physicochemical features of the hybrid surface through nitrogen plasma activation and hetero-phase graphene oxide (GO) covalent functionalization. The surface i…
Inverse Kinematics for a 7 DOF Robotic Arm Using the Redundancy Circle and ANFIS Models
2014
In this paper we have presented a method to solve the inverse kinematics problem of a redundant robotic arm with seven degrees of freedom and a human like workspace based on mathematical equations, ANFIS implementation and Simulink models. For better visualization of the kinematics simulation a CAD model that mimics the real robotic arm was created into SolidWorks® and then the CAD parts were converted into SimMechanics model.
Multisensory texture exploration at the tip of the pen
2016
A tool for the multisensory stylus-based exploration of virtual textures was used to investigate how different feedback modalities (static or dynamically deformed images, vibration, sound) affect exploratory gestures. To this end, we ran an experiment where participants had to steer a path with the stylus through a curved corridor on the surface of a graphic tablet/display, and we measured steering time, dispersion of trajectories, and applied force. Despite the variety of subjective impressions elicited by the different feedback conditions, we found that only nonvisual feedback induced significant variations in trajectories and an increase in movement time. In a post-experiment, using a pa…
Problemes Dimensionament Solar Tèrmica
2018
El document forma part dels materials docents programats mitjançant l'ajut del Servei de Política Lingüística de la Universitat de València. La matèria “Energies Renovables i el seu Condicionament” forma part del bloc comú de matèries pròpies de la branca de Telecomunicacions. S'imparteix en el primer quadrimestre del tercer curs de les titulacions de Grau en Enginyeria Electrònica de Telecomunicació i Grau en Enginyeria Telemàtica i com assignatura optativa al quart curs del Grau en Enginyeria Electrònica Industrial. La càrrega lectiva total és de 6 ECTS. La càrrega de treball per a l’estudiant és de 150 hores al llarg del quadrimestre, de les quals 60 són presencials i 90 són de treball i…
Educatio siglo XXI : revista de la Facultad de Educación
2015
La presencialidad obligatoria en Educación Superior y el creciente número de estudiantes con compromisos familiares justifican la necesidad de conocer las opiniones del alumnado con respecto a la conciliación estudiantil-familiar en el contexto universitario. Se adopta una metodología cualitativa mediante narrativas. Participan de la investigación 27 estudiantes de la Universitat de València y 46 de la Universidad de Alicante, del Grado en Maestro de Educación Primaria. Los resultados evidencian limitaciones, dificultades y demandas ante las nuevas exigencias metodológicas y evaluativas, si se tienen cargas familiares. Se concluye con propuestas académicas, legislativas y de implementación …
3H-DA release evoked by low pH medium and internal H+ accumulation in rat hypothalamic synaptosomes
2002
Focal Cortical Lesions Induce Bidirectional Changes in the Excitability of Fast Spiking and Non Fast Spiking Cortical Interneurons
2014
A physiological brain function requires neuronal networks to operate within a well-defined range of activity. Indeed, alterations in neuronal excitability have been associated with several pathological conditions, ranging from epilepsy to neuropsychiatric disorders. Changes in inhibitory transmission are known to play a key role in the development of hyperexcitability. However it is largely unknown whether specific interneuronal subpopulations contribute differentially to such pathological condition. In the present study we investigated functional alterations of inhibitory interneurons embedded in a hyperexcitable cortical circuit at the border of chronically induced focal lesions in mouse …
Adaptive Number Knowledge in Secondary School Students: Profiles and Antecedents
2019
Cited By :1 Export Date: 10 February 2021 Correspondence Address: McMullen, J.; Department of Teacher EducationFinland; email: jake.mcmullen@utu.fi The present study aims to examine inter-individual differences in adaptive number knowledge in secondary school students. Adaptive number knowledge is defined as a well-connected network of knowledge of numerical characteristics and arithmetic relations. Substantial and relevant qualitative differences in the strategies and expression of adaptive number knowledge have been found in primary school students still in the process of learning arithmetic. We present a study involving 879 seventh-grade students that examines the structure of individual…
Synaptic scaling generically stabilizes circuit connectivity
2011
Neural systems regulate synaptic plasticity avoiding overly strong growth or shrinkage of the connections, thereby keeping the circuit architecture operational. Accordingly, several experimental studies have shown that synaptic weights increase only in direct relation to their current value, resulting in reduced growth for stronger synapses [1]. It is, however, difficult to extract from these studies unequivocal evidence about the underlying biophysical mechanisms that control weight growth. The theoretical neurosciences have addressed this problem by exploring mechanisms for synaptic weight change that contain limiting factors to regulate growth [2]. The effectiveness of these mechanisms i…
Semilunar Granule Cells Are the Primary Source of the Perisomatic Excitatory Innervation onto Parvalbumin-Expressing Interneurons in the Dentate Gyrus
2020
AbstractWe analyzed the origin and relevance of the perisomatic excitatory inputs on the parvalbumin interneurons of the granule cell layer in mouse. Confocal analysis of the glutamatergic innervation showed that it represents ∼50% of the perisomatic synapses that parvalbumin cells receive. This excitatory input may originate from granule cell collaterals, the mossy cells, or even supramammillary nucleus. First, we assessed the input from the mossy cells on parvalbumin interneurons. Axon terminals of mossy cells were visualized by their calretinin content. Using multicolor confocal microscopy, we observed that less than 10% of perisomatic excitatory innervation of parvalbumin cells could or…