Search results for "ARDS"
showing 10 items of 1705 documents
Rights with limits: biocultural rights - between self-determination and conservation of the environment
2015
Kabir Bavikatte has recently argued that a new 'basket' of group rights is emerging from the interpretation of multilateral environmental agreements, domestic law and case law, and from shifts in the development discourse and the struggles of communities. He refers to this new set of rights as 'biocultural rights' and defines them as being all the rights of indigenous peoples and local communities required to secure their stewardship role over their lands and waters. Biocultural rights build on two foundations: the self-determination and cultural diversity of indigenous peoples and local communities, and the conservation of the environment. This article suggests that the second foundation i…
Ieskats Ķīnas avangarda vizuālajā mākslā no 80.-tajiem līdz mūsdienu globālajam tirgum un spilgtākajiem tā māksliniekiem
2021
Ķīnas laikmetīgā māksla ir dzimusi zem vēsturiska sloga. Lai iepazītu sevi, ir jāpazīst savi priekšteči. Balstoties uz šādu sakāmvārdu, darbā tiek analizēti vēsturiski notikumi un personības. Darbā izcelto mākslinieku vēsturiskā pagātne, to bērnība un studiju gadi kas veidojušas viņu unikālo pieeju mākslai. Aizsākoties ĶTR un tās sociālistiskajai programmai, tās ietekmē tika likti pamati mākslas ievirzei vanguardismā, vēlāk sociālajā reālismā sekojot avangarda kustībai un transformējoties par Ķīnas laikmetīgo mākslu. Valsts sociālo un politisko pārmaiņu vidū, cenšoties izdzīvot un rast iespēju izpaust savas ieceres un uzskatus. Tajā pat laikā saglabājot sociālo atbildību pret valsti un vēlm…
Saturation excess runoff numerical simulation
2005
Saturation excess runoff is a relevant process which needs additional experimental and modeling efforts. This work is focused on its numerical modeling. The final objective is the successive interpretation of ongoing experimental monitoring results in two watersheds in different areas of Italy where the saturation excess runoff formation mechanism seems to be important. The numerical solution of the two-dimensional Richards’ equation allows the evaluation of the sensitivity to the various influent parameters : rainfall intensity, soil properties, depth and initial water content, slope and hillslope length. Also the subsurface flow is simulated at the same time, allowing the evaluation of th…
Rethinking vineyard ground management to counter soil tillage erosion
2022
Tillage erosion is a relevant process of soil redistribution in sloping arable land, but little research has analysed the effect of shallow tillage on soil erosion in vineyards. The goal of this study was to quantify the soil tillage effect on soil translocation and erosion at the territorial level in a large vineyard area in Sicily. The soil loss and soil erosion tolerance limits were compared to identify the vineyards with a high risk of soil degradation. An alternative management scenario to traditional tillage was proposed to evaluate the effectiveness of the best management practices on soil conservation. The experimental trials were conducted in 14 vineyards with different slopes and …
Nitrogen losses in vineyards under different types of soil groundcover. A field runoff simulator approach in central Spain
2017
The soils of Mediterranean vineyards are usually managed with continuous tillage, resulting in bare soil, low infiltration and high soil erosion rates. Soil nutrients, such as nitrogen, could be lost dissolved in the runoff, causing a decrease in soil fertility on such degraded soils and producing eutrophication downstream. The influences of groundcover on the soil erosion processes and sediment yields in Mediterranean vineyards have been widely addressed. However, the runoff process itself, excluding the effect of raindrop impacts, has barely been studied. Thus, a field runoff simulator was built to assess runoff and nutrient losses under different soil management strategies in Central Spa…
Application of solid-phase microextraction for determining phenylurea herbicides and their homologous anilines from vegetables.
2004
Abstract Residues of metobromuron, monolinuron and linuron herbicides and their aniline homologous were analyzed in carrots, onions and potatoes by solid-phase microextraction (SPME) performed with a polyacrylate fiber. A juice was obtained from food samples that were further diluted, and an aliquot was extracted after sodium chloride (14%) addition and pH control. At pH 4 only the phenylureas were extracted. A new extraction at pH 11 allowed the extraction of phenylureas plus homologous aniline metabolites. Determination was carried out by gas chromatography with nitrogen–phosporus detection (NPD) the identity of the determined compounds was studied by gas chromatography–mass spectrometry.…
Sorafenib in advanced hepatocellular carcinoma
2008
none 25 BACKGROUND: No effective systemic therapy exists for patients with advanced hepatocellular carcinoma. A preliminary study suggested that sorafenib, an oral multikinase inhibitor of the vascular endothelial growth factor receptor, the platelet-derived growth factor receptor, and Raf may be effective in hepatocellular carcinoma. METHODS: In this multicenter, phase 3, double-blind, placebo-controlled trial, we randomly assigned 602 patients with advanced hepatocellular carcinoma who had not received previous systemic treatment to receive either sorafenib (at a dose of 400 mg twice daily) or placebo. Primary outcomes were overall survival and the time to symptomatic progression. Seconda…
Survival analysis of proposed BCLC-B subgroups in hepatocellular carcinoma patients
2013
Background & Aims The BCLC-staging system is used to facilitate treatment decisions in patients with hepatocellular carcinoma (HCC). Owing to the observed clinical heterogeneity of the intermediate stage BCLC-B, a subclassification was proposed taking Child–Pugh score and extended criteria for transplantation into account. Analysis of the prognostic significance of a proposed subclassification of the BCLC-B score in a European cohort of HCC patients. Methods Eight hundred and eighty four consecutive HCC patients were retrospectively analysed. Patients with stage BCLC-B were grouped according to the proposed subclassification. Baseline patient and tumour characteristics, therapy and overall …
Improved prediction of survival by a risk factor-integrated inflammatory score in Sorafenib treated hepatocellular carcinoma
2017
Background and aims Inflammation affects progression of hepatocellular carcinoma (HCC). We therefore postulate that systemic inflammatory markers could help to predict prognosis in HCC patients receiving sorafenib therapy. Methods Overall survival (OS) of HCC patients receiving palliative sorafenib treatment was correlated with the neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), C-reactive protein to albumin ratio (CAR), Glasgow prognostic score (GPS) and the modified GPS (mGPS) along with clinicopathological parameters. Predictors of OS were assessed by multivariable Cox regression and receiver operating characteristics and area under the curve (ROC-AUC) analyses.…
Ramucirumab in elderly patients with hepatocellular carcinoma and elevated alpha-fetoprotein after sorafenib in REACH and REACH-2.
2020
Background & Aims: Limited data on treatment of elderly patients with hepatocellular carcinoma (HCC) increase the unmet need. REACH and REACH-2 were global phase III studies of ramucirumab in patients with HCC after prior sorafenib, where patients with alpha-fetoprotein (AFP) ≥400 ng/mL showed an overall ssurvival (OS) benefit for ramucirumab. These post-hoc analyses examined efficacy and safety of ramucirumab in patients with HCC and baseline AFP ≥ 400 ng/mL by three prespecified age subgroups (<65, ≥65 to <75 and ≥75 years). Methods: Individual patient data were pooled from REACH (baseline AFP ≥400 ng/mL) and REACH-2. Kaplan-Meier and Cox proportional hazards regression methods …