Search results for "ARTERIAL"
showing 10 items of 714 documents
Stability of irinotecan-loaded drug eluting beads (DC BeadTM) used for transarterial chemoembolization
2009
Purpose. The aim of this study was to determine the loading efficiency, physicochemical stability, and release of irinotecan-loaded DC BeadsTM (bead size 100—300 μm, 300—500 μm) before and after mixing with nonionic contrast medium (Accupaque® 300, Imeron® 300, Ultravist ® 300) during a prolonged period of time (28 days) when stored at room temperature or refrigerated. Methods. DC Beads TM were loaded with 50 mg irinotecan (Campto®) per milliliter beads in a 2 h loading period. Drug loading efficiency and stability were determined by measuring the irinotecan concentration in the excess solution. A free-flowing in vitro elution method for a period of 2 h and phosphate buffered solution (PBS…
Práctica 2. Valoración clínico-funcional en afecciones cardíacas
2011
La exploración clínico-funcional aporta las claves para el diagnóstico de las afecciones cardíacas. Si bien la Anamnesis es el procedimiento diagnóstico primario, se precisan exploraciones complementarias para realizar un correcto diagnóstico diferencial. En este sentido, son necesarios los tres elementos de la exploración física cardiovascular (inspección, palpación y auscultación) y pruebas complementarias como: el registro electrocardiográfico, la toma de la tensión arterial, la radiografía de tórax, el estudio ecocardiográfico, el cateterismo cardíaco, etc. L’exploració clínico-funcional aporta les claus per al diagnòstic de les afeccions cardíaques. A més de l’Anamnesi o procediment di…
RELATIONSHIP BETWEEN VITAMIN D STATUS AND EARLY ARTERIAL CHANGES IN PRIMARY HYPERTENSION. PRELIMINARY DATA
2011
Ventricular-vascular coupling in hypertension: methodological considerations and clinical implications.
2014
The present review is addressed to analyse the complex interplay between left ventricle and arterial tree in hypertension. The different methodological approaches to the analysis of ventricular vascular coupling in the time and frequency domain are discussed. Moreover, the role of hypertension-related changes of arterial structure and function (stiffness and wave reflection) on arterial load and how ventricular-vascular coupling modulates the process of left ventricular adaptation to hypertension are analysed.The different interplay between vascular bed and left ventricle emerges as the pathophysiological basis for the development of the multiple patterns of ventricular structural adaptatio…
Reproducibility of pulse wave velocity and augmentation index derived from non-invasive occlusive oscillometric tonometry analysis in adolescents
2019
The aim of this study was to investigate the short‐term reproducibility of aortic pulse wave velocity (PWVao) and augmentation index (AIx%) assessed by the non‐invasive oscillometric device. Altogether of 55 (19 boys, 36 girls) adolescents 16–19‐years‐of‐age participated in the study. PWVao and AIx% were measured during the same laboratory visit at 2 min intervals using the Arteriograph™ device. Peak oxygen uptake (V̇O2peak) was assessed by the maximal exercise test on a cycle ergometer and body fat percentage by bioelectrical impedance analysis. We studied reproducibility using intraclass correlation coefficients (ICC), coefficient variation with the root‐means‐square method expressed as p…
Relationship between total arterial compliance and metabolic syndrome in essential hypertensive subjects
2007
Characterizing Diagnostic Inertia in Arterial Hypertension With a Gender Perspective in Primary Care
2022
Background and ObjectivesSubstantial evidence shows that diagnostic inertia leads to failure to achieve screening and diagnosis objectives for arterial hypertension (AHT). In addition, different studies suggest that the results may differ between men and women. This study aimed to evaluate the differences in diagnostic inertia in women and men attending public primary care centers, to identify potential gender biases in the clinical management of AHT.Study Design/Materials and MethodsCross-sectional descriptive and analytical estimates were obtained nested on an epidemiological ambispective cohort study of patients aged ≥30 years who attended public primary care centers in a Spanish region …
RELATIONSHIP BETWEEN ASYMPTOMATIC HYPERURICEMIA AND RENAL FUNCTION DECLINE IN HYPERTENSIVE SUBJECTS.
2013
Introduction: It is well known that the deposition of uric acid crystals exert direct toxic effect on the renal parenchyma and vasculature. Both experimental and some clinical studies suggest the possibility that an increased uric acid level can lead to kidney disease even without deposition of uric acid crystals. However, other studies yielded conflicting results, especially regarding the role of uric acid in the progression of established kidney disease. Aim: To evaluate retrospectively the relationship between asymptomatic hyperuricemia and renal function decline in non-gouty hypertensive patients. Methods: We enrolled 97 hypertensive subjects, 48 with chronic kidney diseases (CKD) and 4…
The Metabolic Syndrome and Its Relationship to Hypertensive Target Organ Damage
2007
High blood pressure is often associated with various metabolic abnormalities, including abdominal obesity, dyslipidemia, elevated plasma glucose, and insulin resistance, which are the main features of the metabolic syndrome. The metabolic syndrome is extremely common worldwide. This high prevalence is of considerable concern because several studies suggest that the metabolic syndrome carries an increased risk for cardiovascular events. Several lines of evidence seem to indicate that the metabolic syndrome is associated with an increased prevalence of preclinical cardiovascular and renal changes, such as left ventricular hypertrophy, microalbuminuria, impaired aortic elasticity, and early ca…