Search results for "ARTICLES"
showing 10 items of 9626 documents
Stimuli-responsive magnetic coordination polymers: from crystals to nanoparticles
2013
El trabajo descrito en esta tesis se enmarca en el ámbito de los polímeros de coordinación (PC). Estos sistemas representan un área importante dentro de la Química de los Materiales, siendo principalmente interesantes sus aplicaciones en catálisis, electrónica y óptica. Su origen data de principios de los años 60, donde se produjo la primera revisión de estructuras de compuestos inorgánicos que formaban cadenas.1 Los PC están formados por ligandos orgánicos y metales enlazados por enlaces de coordinación que se extienden infinitamente en 1, 2 o 3 dimensiones. En cuanto a su versatilidad química, las estructuras y propiedades varían en función de los metales o ligandos utilizados. Así pues, …
Caracterización proteómica de la interacción y la inserción de proteínas de membrana
2019
Las proteínas de membrana tienen funciones muy diversas en la célula, desde controlar el tráfico molecular hasta facilitar la transducción de señales. Sin embargo, el estudio de estas proteínas supone todo un reto por sus particulares características fisico-químicas. Su naturaleza hidrofóbica requiere un elevado control durante su síntesis. Uno de los pasos críticos en esta síntesis es la inserción en la bicapa lipídica. Generalmente, este proceso se produce a través de un mecanismo (co-traduccional) acoplado al proceso de traducción. Esta vía co-traduccional ha sido ampliamente estudiada y la maquinaria implicada en el proceso se conoce con bastante profundidad. Sin embargo, algunas proteí…
A new efficient, highly dispersed, Pd nanoparticulate silica supported catalyst synthesized from an organometallic precursor. Study of the homogeneou…
2018
[EN] A new Pd(0) catalyst supported on silica UVM-7 has been synthesized from the organometallic [Pd-2(mu-(C6H4) Pp(2))(2)(CH3CN)(4)](BF4)(2) precursor, characterized by the high dispersion, activity, and small size of the palladium nanoclusters fixed on the silica surface. The catalyst was tested for the Suzuki-Miyaura (SM) reaction of different 4-substitutedphenyl halides with phenylboronic acid. The kinetic study concurs with most of the catalytic action was carried out by Pd species originated by the partial solubilization of Pd immobilized on mesoporous silica. The Schmidt's analysis of differential selectivity (SADS) in several competitive SM reactions, together the STEM-HAADF and HRT…
Kinetic characterization of mitochondrial complex I inhibitors using annonaceous acetogenins
1999
The NADH:ubiquinone oxidoreductase (complex I) of the mitochondrial respiratory chain is by far the largest and most complicated of the proton-translocating enzymes involved in the oxidative phosphorylation. Many clues regarding the electron pathways from matrix NADH to membrane ubiquinone and the links of this process with the translocation of protons are highly controversial. Different types of inhibitors become valuable tools to dissect the electron and proton pathways of this complex enzyme. Therefore, further knowledge of the mode of action of complex I inhibitors is needed to understand the underlying mechanism of energy conservation. This study presents for the first time a detailed …
Trigger and aperture of the surface detector array of the Pierre Auger Observatory
2010
The surface detector array of the Pierre Auger Observatory consists of 1600 water-Cherenkov detectors, for the study of extensive airshowers (EAS) generated by ultra-high-energy cosmic rays. We describe the trigger hierarchy, from the identification of candidates howers at the level of a single detector, amongst a large background (mainly random single cosmic ray muons), up to the selection of real events and the rejection of random coincidences. Such trigger makes the surface detector array fully efficient for the detection of EAS with energy above 3 x 1018 eV, for all zenith angles between 03 and 603, independently of the position of the impact point and of the mass of the primary particl…
Quasi-periodic dipping in the ultraluminous X-ray source, NGC 247 ULX-1
2021
Most ultraluminous X-ray sources (ULXs) are believed to be stellar mass black holes or neutron stars accreting beyond the Eddington limit. Determining the nature of the compact object and the accretion mode from broadband spectroscopy is currently a challenge, but the observed timing properties provide insight into the compact object and details of the geometry and accretion processes. Here we report a timing analysis for an 800 ks XMM-Newton campaign on the supersoft ultraluminous X-ray source, NGC 247 ULX-1. Deep and frequent dips occur in the X-ray light curve, with the amplitude increasing with increasing energy band. Power spectra and coherence analysis reveals the dipping preferential…
Protective effect of trehalose-loaded liposomes against UVB-induced photodamage in human keratinocytes
2014
Trehalose, a naturally occurring non-reducing disaccharide, is known to act as a major protein stabilizer that can reduce ultraviolet B (UVB)-induced corneal damage when topically applied to the eye. However, due to the low skin permeability of trehalose, which makes the development of topical formulations difficult, its use as a skin photoprotective agent has been limited. Previous findings demonstrated that liposomes may significantly improve the intracellular delivery of trehalose. Therefore, the present study aimed to assess the protective effects of trehalose-loaded liposomes against UVB-induced photodamage using the immortalized human keratinocyte cell line, HaCaT. The effects were al…
Maxwell-Dirac Theory and Occam's Razor: Unified Field, Elementary Particles, and Nuclear Interactions
2019
We introduce and use the space-time Clifford algebra, showing that only one fundamental physical entity is sufficient to describe the origin of electromagnetic fields, charges and currents: the electromagnetic four-potential. This simplified electromagnetic model turns out to be an improved understanding of electromagnetism. The obtained electromagnetic Lagrangian is the simplest possible relativistic Lagrangian formulation. Quantum mechanical relations follow naturally from this model, and we derive the electromagnetic formulation of the Dirac equation. The spinor field is shown to correspond to electromagnetic energy-momentum, and the complex-valued probability density is shown to corresp…
Search for transient sources with the ANTARES and KM3NeT neutrino telescopes in the multi-messenger astronomy era
2020
En el presente manuscrito se expone el trabajo realizado en el seno de la Collaboración ANTARES-KM3NeT sobre la astronomía multi-mensanjero con neutrinos, que se ha enfocado en dos ejes: la detección de neutrinos de supernova a bajas energías (MeV) con los telecopios KM3NeT y la búsqueda de neutrinos de alta energía (TeV-PeV) en ANTARES en coincidencia con fuentes transitorias detectadas en ondas gravitationales o rayos gamma de muy alta energía O(TeV). El primer análisis, explora la capacidad de los telescopios de neutrinos KM3NeT para detectar la señal de una explosión de supernova (CCSN), así como el potencial de explotar dicha detección para aprender sobre la física que hay detrás, en p…
Influence of artificial aging and ZrO2 nanoparticle-reinforced repair resin on the denture repair strength
2019
Background The purpose of this study was to evaluate the effect of aging process on the tensile strength (TS) of repaired acrylic denture base using ZrO2 nanoparticles (nano-ZrO2)-reinforced autopolymerized resin. Material and Methods A total of 240 heat-polymerized acrylic resin specimens (n=10) were prepared and sectioned creating 2 mm-repair-gap. Autopolymerized acrylic resin, pure and modified with 2.5, 5, and 7.5wt% nano-ZrO2 were used for specimens repair. TS of repaired specimens were measured using the universal testing machine after water immersion at 37oC for 2, 7 and 30 days. At each time interval, half the immersed specimens underwent thermo-cycling aging process (5000 cycles at…