Search results for "ASES"

showing 10 items of 26804 documents

Kuormituskoe modernin kuvantamisen aikakaudella

2019

Kuormituskoetta käytetään sepelvaltimotaudin ja muidenkin sydänsairauksien diagnosoinnissa, ennusteen arvioinnissa, hoidon suunnittelussa ja seurannassa. Kuormituskokeen keskeisin etu on sen helppo saatavuus sekä avoterveydenhuollossa että erikoissairaanhoidossa. Rasitukseen liittyvien oireiden tai suorituskyvyn heikkenemisen yhteydessä kuormituskoe on edelleen arvokas perustutkimus. Sen käytön keskeisin rajoite liittyy sen diagnostiseen osuvuuteen, ja sepelvaltimotaudin ali- ja ylidiagnostiikan välttämiseksi kuormituskokeen käyttö tulisikin rajata liikuntakykyisiin potilaisiin, joilla taudin todennäköisyys ennen testiä on keskisuuri tai suuri. Kuormituskoe sopii potilaille, joiden lepo-EKG…

rasituskokeetheart diseaseskuvantaminencoronary artery disease (CAD)sepelvaltimotautidiagnosticstolerance testssydäntauditdiagnostiikka
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Topological canal foliations

2019

Regular canal surfaces of $\mathbb{R}^3$ or $\mathbb{S}^3$ admit foliations by circles: the characteristic circles of the envelope. In order to build a foliation of $\mathbb{S}^3$ with leaves being canal surfaces, one has to relax the condition “canal” a little (“weak canal condition”) in order to accept isolated umbilics. Here, we define a topological condition which generalizes this “weak canal” condition imposed on leaves, and classify the foliations of compact orientable 3-manifolds we can obtain this way.

rational parametrizationsQuantitative Biology::Tissues and OrgansGeneral MathematicsPhysics::Medical PhysicssurfacesTopology01 natural sciencesQuantitative Biology::Cell Behavior0103 physical sciencesotorhinolaryngologic diseases57R30[MATH]Mathematics [math]0101 mathematicsMathematicsEnvelope (waves)griddlingQuantitative Biology::Molecular Networks010102 general mathematicsOrder (ring theory)53C12foliationFoliation (geology)sense organsMathematics::Differential Geometry010307 mathematical physicscanal surfaceJournal of the Mathematical Society of Japan
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Oxidative and nitrosative stress in the metastatic microenvironment.

2010

Metastases that are resistant to conventional therapies are the main cause of most cancer-related deaths in humans. Tumor cell heterogeneity, which associates with genomic and phenotypic instability, represents a major problem for cancer therapy. Additional factors, such as the attack of immune cells or organ-specific microenvironments, also influence metastatic cell behavior and the response to therapy. Interaction of cancer and endothelial cells in capillary beds, involving mechanical contact and transient adhesion, is a critical step in the initiation of metastasis. This interaction initiates a cascade of activation pathways that involves cytokines, growth factors, bioactive lipids and r…

reactive oxygen speciesCancer ResearchTumor microenvironmentCancerReviewBiologylcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensmedicine.diseaselcsh:RC254-282Primary tumorMetastasischemistry.chemical_compoundImmune systemreactive nitrogen speciesOncologychemistryImmunologyCancer cellmedicineCancer researchCytotoxic T celltumor microenvironmentmetastasesReactive nitrogen speciesCancers
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Global Real-World Evidence of Sofosbuvir/Velpatasvir as a Highly Effective Treatment and Elimination Tool in People with Hepatitis C Infection Experi…

2022

HCV elimination; Mental health disorders; Sofosbuvir/velpatasvir Eliminación del VHC; Trastornos de salud mental; Sofosbuvir/velpatasvir Eliminació del VHC; Trastorns de salut mental; Sofosbuvir/velpatasvir Hepatitis C virus (HCV) is prevalent in people with mental health disorders, a priority population to diagnose and cure in order to achieve HCV elimination. This integrated analysis pooled data from 20 cohorts in seven countries to evaluate the real-world effectiveness of the pangenotypic direct-acting antiviral (DAA) sofosbuvir/velpatasvir (SOF/VEL) in people with mental health disorders. HCV-infected patients diagnosed with mental health disorders who were treated with SOF/VEL for 12 w…

real-worldGenotype:Mental Disorders [PSYCHIATRY AND PSYCHOLOGY]:Otros calificadores::Otros calificadores::/farmacoterapia [Otros calificadores]Hepacivirus:Other subheadings::Other subheadings::/drug therapy [Other subheadings]Antiviral AgentsMental health disordersVirologyMedicaments antivírics - Ús terapèuticHumans:Other subheadings::/therapeutic use [Other subheadings]sofosbuvir/velpatasvir:trastornos mentales [PSIQUIATRÍA Y PSICOLOGÍA]:Otros calificadores::/uso terapéutico [Otros calificadores]Mental Disorders:virosis::hepatitis viral humana::hepatitis C [ENFERMEDADES]:Virus Diseases::Hepatitis Viral Human::Hepatitis C [DISEASES]HCV elimination; HCV; mental health disorders; real-world; sofosbuvir/velpatasvirHepatitis C:Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Antiviral Agents [CHEMICALS AND DRUGS]Infectious DiseasesReal-worldSofosbuvir/velpatasvirHCV elimination:acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antiinfecciosos::antivíricos [COMPUESTOS QUÍMICOS Y DROGAS]HCVmental health disordersSofosbuvirMalalties mentalsHepatitis C - TractamentViruses
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La relevancia de la investigación social a nivel local para el diseño de políticas municipales: el diagnóstico social de la ciudad de Valencia

2019

Presentamos algunos de los resultados obtenidos con la investigación ?Diagnóstico Social de la Ciudad de València, 2017?, realizada en el marco de un convenio de colaboración entre el Ayuntamiento de València, a través de la Concejalía de Servicios Sociales y del Servicio de Bienestar Social e Integración y la Universitat de València (Red Incluye). Uno de los rasgos más relevantes de la investigación fue su enfoque local, territorial y subterritorial en el desarrollo metodológico y técnico de la investigación al estarorientada a proporcionar información actualizada, inédita y relevante para las funciones del personal técnico de las once áreas de los Centros Municipales de Servicios Sociales…

realizada en 1.676 hogares de la ciudad de Valencia entre los meses de abril a julio del 2017. Con once submuestras independientes para cada área de CMSS. Los resultados aportan una visión en el espacio local-urbano de la ciudad de València de los procesos de polarización y agudización de las desigualdades socialesValència CityRaúl Presentamos algunos de los resultados obtenidos con la investigación ?Diagnóstico Social de la Ciudad de ValènciaAROPEterritorial y subterritorial en el desarrollo metodológico y técnico de la investigación al estarorientada a proporcionar información actualizadaRisk of Poverty and Social Exclusion (AROPE) 101 118periodo 2003-2016. La segunda fase fue elaborada en base a una encuestaValència:SOCIOLOGÍA [UNESCO]elaborada por el equipo de investigaciónExclusión1137-7038 8537 Arxius de sociologia 525290 2019 40 7038145 La relevancia de la investigación social a nivel local para el diseño de políticas municipales: el diagnóstico social de la ciudad de Valencia Ramírez Rangelrealizada en el marco de un convenio de colaboración entre el Ayuntamiento de Valènciacaracterizados por la consolidación de áreas en donde los efectos de la crisis económica han sido prácticamente imperceptibles y otros donde se observa una concentración de la población en situación de riesgo pobreza y vulnerabilidad relacionada tanto con la cristalización de largos procesos de exclusión como con el surgimiento de ?nuevos perfiles? de vulnerabilidad. Diagnóstico sociala través de la Concejalía de Servicios Sociales y del Servicio de Bienestar Social e Integración y la Universitat de València (Red Incluye). Uno de los rasgos más relevantes de la investigación fue su enfoque localJ. Verónicainédita y relevante para las funciones del personal técnico de las once áreas de los Centros Municipales de Servicios Sociales (CMSS). El diagnóstico consta de dos fases. En la primera se realizó un análisis de las principales tendencias socio demográficas en cada área de los CMSSUNESCO::SOCIOLOGÍA2017?Lorente CamposPobrezael diagnóstico social de la ciudad de Valencia Ramírez Rangel [1137-7038 8537 Arxius de sociologia 525290 2019 40 7038145 La relevancia de la investigación social a nivel local para el diseño de políticas municipales]Local Diagnosis
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An Automatic Ontology-Based Approach to Support Logical Representation of Observable and Measurable Data for Healthy Lifestyle Management: Proof-of-C…

2020

Background Lifestyle diseases, because of adverse health behavior, are the foremost cause of death worldwide. An eCoach system may encourage individuals to lead a healthy lifestyle with early health risk prediction, personalized recommendation generation, and goal evaluation. Such an eCoach system needs to collect and transform distributed heterogenous health and wellness data into meaningful information to train an artificially intelligent health risk prediction model. However, it may produce a data compatibility dilemma. Our proposed eHealth ontology can increase interoperability between different heterogeneous networks, provide situation awareness, help in data integration, and discover…

recommendationDatabases Factual020205 medical informaticsComputer scienceinteroperabilityHealth Informatics02 engineering and technologyOntology (information science)SNOMED CTcomputer.software_genrelcsh:Computer applications to medicine. Medical informaticsProof of Concept Studysensorhealthy lifestyle0202 electrical engineering electronic engineering information engineeringHumansSPARQLontologypropositionRDFsemanticsSemantic Webcomputer.programming_languagegoal settingOriginal PaperSSNInformation retrievalactivityquestionnairelcsh:Public aspects of medicinepersonalizedlcsh:RA1-1270eCoachcomputer.file_formatSemantic reasonerProtégésimulationTelemedicinenutritionautomatedlcsh:R858-859.7eHealth020201 artificial intelligence & image processingCDSScomputerRDF query languageData integrationJournal of Medical Internet Research
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Reflecting through the designing: a brief analysis of the teacher’s planning process

2016

The aim of this work is to study the conditions in which teachers plan and execute educational actions in the classroom and to find out which difficulties they encountered during the development of the planned teaching action. The “concrete operations” that 15 teachers in the Palermo area had accomplished, were highlighted before, during and after every structured activity to promote the pupils’ oral expression. Specifically, the research, which is collocated in the case study, had the function of verifying forty descriptors. These were grouped in the five cardinal points of the ADDIE model (Analysis, Design, Development, Implementation, Evaluation), with a motivated group of teachers that …

reflective practiceteaching planningphases of instructional designfasi di progettazionepratica riflessivalcsh:Lprogrammazione didatticaSettore M-PED/03 - Didattica E Pedagogia Specialelcsh:EducationForm@re : Open Journal per la Formazione in Rete
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Crear y gestionar conocimiento en red: agentes y procesos implicados.

2013

El proposito de este articulo es delimitar las funciones y roles de los principales agentes y los procesos que intervienen en la creacion y gestion del conocimiento (CGC) en red desde una plataforma virtual. Recoge, al respecto, algunos de los resultados mas destacados que se derivan de la investigacion “Agentes y procesos en la gestion del conocimiento en red” (I+D+i). El proceso de investigacion seguido ha supuesto, fundamentalmente, la puesta en marcha de 5 redes de CGC desde una plataforma virtual (Moodle) sostenida en el debate como estrategia; tambien la realizacion de un trabajo de campo que considero un cuestionario de autodiagnostico para 15 directivos y especialistas en desarrollo…

reflexión pedagógicagestión del conocimientotecnologías de la información y la comunicacióntecnologías de la información y la comunicación; educación; pedagogía; gestión del conocimientoprácticas educativastrabajo colaborativopedagogíamodelosVirtualidad; bases psicopedagógicas; gestión del conocimiento; trabajo colaborativo; reflexión pedagógica; modelos; prácticas educativaseducaciónVirtualidadbases psicopedagógicas@tic. revista d'innovació educativa
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Measurement of Physical Fitness and 24/7 Physical Activity, Standing, Sedentary Behavior, and Time in Bed in Working-Age Finns : Study Protocol for F…

2022

Background: Population studies gathering measured data on fitness and physical behavior, covering physical activity, standing, sedentary behavior, and time in bed, are scarce. This article describes the protocol of the FINFIT 2021 study that measures fitness and physical behavior in a population-based sample of adults and analyzes their associations and dose–response relationships with several health indicators. Methods: The study comprises a stratified random sample of 20–69-year-old men and women (n = 16,500) from seven city-centered regions in Finland. Physical behavior is measured 24/7 by tri-axial accelerometry and analyzed with validated MAD-APE algorithms. Health and fitness examinat…

registernoncommunicable diseasesväestötutkimusterveydentilahealthactive traveltyöikäisetBiochemistry Genetics and Molecular Biology (miscellaneous)3142 Public health care science environmental and occupational healthfitnessaccelerometerfyysinen kuntoStructural BiologyProtocoladults315 Sport and fitness sciencesfyysinen aktiivisuusBiotechnology
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Jet fragmentation transverse momentum distributions in pp and p-Pb collisions at √s, √sNN = 5.02 TeV

2021

Jet fragmentation transverse momentum (jT) distributions are measured in proton-proton (pp) and proton-lead (p-Pb) collisions at √sNN = 5.02 TeV with the ALICE experiment at the LHC. Jets are reconstructed with the ALICE tracking detectors and electromagnetic calorimeter using the anti-kT algorithm with resolution parameter R = 0.4 in the pseudorapidity range |η| < 0.25. The jT values are calculated for charged particles inside a fixed cone with a radius R = 0.4 around the reconstructed jet axis. The measured jT distributions are compared with a variety of parton-shower models. Herwig and Pythia 8 based models describe the data well for the higher jT region, while they underestimate the low…

related to the perturbative component of the fragmentation processthe measured trends are successfully described by all models except for Herwig. For the wide componentHerwig and PYTHIA 8 based models slightly underestimate the data for the higher jet transverse momentum region. These measurements set constraints on models of jet fragmentation and hadronisation.Nuclear and High Energy Physicswhile that of the inverse gamma function increases with increasing jet transverse momentum. For the narrow componentHeavy Ion Experimentsand with a Gaussian for lower jT values (called the “narrow component”)hiukkasfysiikkawhile they underestimate the lower jT region. The jT distributions are further characterised by fitting them with a function composed of an inverse gamma function for higher jT values (called the “wide component”)predominantly connected to the hadronisation process. The width of the Gaussian has only a weak dependence on jet transverse momentumJet fragmentation transverse momentum (jT) distributions are measured in proton-proton (pp) and proton-lead (p-Pb) collisions at √sNN = 5.02 TeV with the ALICE experiment at the LHC. Jets are reconstructed with the ALICE tracking detectors and electromagnetic calorimeter using the anti-kT algorithm with resolution parameter R = 0.4 in the pseudorapidity range |η| < 0.25. The jT values are calculated for charged particles inside a fixed cone with a radius R = 0.4 around the reconstructed jet axis. The measured jT distributions are compared with a variety of parton-shower models. Herwig and PYTHIA 8 based models describe the data well for the higher jT region
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