Search results for "ASSOCIATION"

showing 10 items of 1747 documents

The Association Between Epigenetic Clocks and Physical Functioning in Older Women: A 3-Year Follow-up

2021

Abstract Background Epigenetic clocks are composite markers developed to predict chronological age or mortality risk from DNA methylation (DNAm) data. The present study investigated the associations between 4 epigenetic clocks (Horvath’s and Hannum’s DNAmAge and DNAm GrimAge and PhenoAge) and physical functioning during a 3-year follow-up. Method We studied 63- to 76-year-old women (N = 413) from the Finnish Twin Study on Aging. DNAm was measured from blood samples at baseline. Age acceleration (AgeAccel), that is, discrepancy between chronological age and DNAm age, was determined as residuals from linear model. Physical functioning was assessed under standardized laboratory conditions at b…

EpigenomicsAgingfyysinen toimintakykyEpigenesis Genetic03 medical and health sciences0302 clinical medicinePhysical functioningMedicineHumans030212 general & internal medicineEpigeneticsAssociation (psychology)030304 developmental biology0303 health sciencesbusiness.industryLinear modelRepeated measures designdNaMDNA MethylationMissing dataTwin studyDNA-metylaatioikääntyminenCross-Sectional Studiesepigenetiikkabiological aging3121 General medicine internal medicine and other clinical medicineFemaleGeriatrics and Gerontologybusinessepigenetic clockDemographyFollow-Up Studies
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Extensive molecular analysis of patients bearing CFTR-related disorders.

2012

Cystic fibrosis transmembrane conductance regulator (CFTR)–related disorders (CFTR-RDs) may present with pancreatic sufficiency, normal sweat test results, and better outcome. The detection rate of mutations is lower in CFTR-RD than in classic CF: mutations may be located in genes encoding proteins that interact with CFTR or support channel activity. We tested the whole CFTR coding regions in 99 CFTR-RD patients, looking for gene mutations in solute carrier (SLC) 26A and in epithelial Na channel (ENaC) in 33 patients who had unidentified mutations. CFTR analysis revealed 28 mutations, some of which are rare. Of these mutations, RT-PCR demonstrated that the novel 1525-1delG impairs exon 10 s…

Epithelial sodium channelcongenital hereditary and neonatal diseases and abnormalitiesCystic fibrosis CFTR SLC26A SCNNCystic FibrosisAnion Transport ProteinsDNA Mutational Analysismolecular analysiCystic Fibrosis Transmembrane Conductance RegulatorGene mutationPathology and Forensic Medicinecongenital bilateral absence of vasa deferentesExonGene Frequencydisseminated bronchiectasiscongenital bilateral absence of vasa deferenteHumansTrypsinmolecular analysisEpithelial Sodium ChannelsGeneCells CulturedGenetic Association StudiesGeneticsbiologydisseminated bronchiectasiEpithelial Cellsrespiratory systemrecurrent pancreatitidigestive system diseasesCystic fibrosis transmembrane conductance regulatorrespiratory tract diseasesSolute carrier familyCFTR related disordersTrypsin Inhibitor Kazal PancreaticCase-Control StudiesRNA splicingMutationbiology.proteinMolecular MedicineCFTR related disorderSLC26 familyCarrier ProteinsNa channel ENaCMinigenerecurrent pancreatitis
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Conductance of potassium lodide in mixed solvents

1976

The conductance of potassium iodide has been measured in the solvents ethylene carbonate, water, methyl ethyl ketone, and pairwise mixtures of these solvents at 40°C; and ethylene carbonate-water, tetramethylene sulfone-water, dimethyl sulfoxide-water, tetrahydrofuran-water, ethylene carbonate-tetramethylene sulfone-water, ethylene carbonate-tetramethylene sulfone, and tetrahydrofuran-dimethyl sulfoxide at 25°C. For dielectric constants greater than about 60, the pairing constants KA are in the range 0.3–2.0; no correlation between KA and solvent properties could be established. For lower dielectric constants, KA increases exponentially with decreasing dielectric constant. Addition of a pro…

EthyleneChemistryPotassiumInorganic chemistryBiophysicsConductancechemistry.chemical_elementSulfoxideDielectricIon-associationBiochemistrySolventchemistry.chemical_compoundPhysical and Theoretical ChemistryMolecular BiologyEthylene carbonateJournal of Solution Chemistry
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Le plurilinguisme au sein d'AEGEE

2009

4 pages à partir de la présentation orale, lors des "Premières assises européennes du plurilinguisme" en novembre 2005; Ce chapitre décrit et analyse les pratiques langagières observées (langues parlées) au sein de l'association étudiante AEGEE. Il examine la question du multilinguisme au sein de l'association étudiante AEGEE, et constate une tension entre trois occurrences complémentaires : le recours pragmatique à une langue véhiculaire, l'idéal d'une communauté polyglotte, et un plurilinguisme spontané dans certaines situations.

Europecommunication interculturellehégémonie linguistique[SHS.INFO]Humanities and Social Sciences/Library and information sciencesMultilingualintercultural communication[ SHS.INFO ] Humanities and Social Sciences/Library and information sciencesassociation[SHS.INFO] Humanities and Social Sciences/Library and information scienceslinguistic hegemonyplurilinguisme
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Le fonctionnement d'un espace utopique européen

2008

12 pages; Ce chapitre présente la notion d'« espace utopique », définie à partir de la réflexion de Paul Ricœur. En examinant la manière dont l'association étudiante AEGEE se construit en tant qu'espace utopique, ainsi que les conséquences pour son fonctionnement, le chapitre tente d'apporter un nouvel éclairage aux travaux, menés par Éric Dacheux, sur les « associations européennes de citoyenneté ».

Europeutopiecommunication interculturelleespace utopiqueassociation européenne de citoyennetéEuropean associationutopia[SHS.INFO]Humanities and Social Sciences/Library and information sciencesintercultural communication[ SHS.INFO ] Humanities and Social Sciences/Library and information sciences[SHS.INFO] Humanities and Social Sciences/Library and information sciences
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Działalność Związku Polskiej Młodzieży Ewangelickiej Województwa Śląskiego w latach 1927–1939

2022

Problematyce aktywizacji i wychowania młodzieży ewangelickiej w okresie międzywojennym poświęcano wiele uwagi, ponieważ stanowiła ona o przyszłości Kościoła, społeczeństwa i odrodzonego narodu. Celem artykułu jest próba uszczegółowienia – z perspektywy pedagogicznej – głównych obszarów działalności stowarzyszenia „Związku Polskiej Młodzieży Ewangelickiej Województwa Śląskiego”. Scharakteryzowano uwarunkowania powstania i rozwoju związku, uwzględniając zakres jego oddziaływania patriotyczno-religijnego, kulturalno-oświatowego i społecznego, przygotowującego młodzież do pełnienia ważnych obowiązków religijnych, społeczno-oświatowych i narodowych w swym otoczeniu. Omówiono również założenia ew…

Evangelical youthstowarzyszeniacultural-education-al activitymłodzież ewangelickapatriotic-religious activitydziałalność kulturalno-oświatowadziałalność patriotyczno-religijnaassociationsStudia Teologiczno-Historyczne Śląska Opolskiego
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Positive selection at codon 38 of the human KCNE1 (= minK) gene and sporadic absence of 38Ser-coding mRNAs in Gly38Ser heterozygotes

2009

Abstract Background KCNE1 represents the regulatory beta-subunit of the slowly activating delayed rectifier potassium channel (IKs). Variants of KCNE1 have repeatedly been linked to the long-QT syndrome (LQTS), a disorder which predisposes to deafness, ventricular tachyarrhythmia, syncope, and sudden cardiac death. Results We here analyze the evolution of the common Gly38Ser variant (rs1805127), using genomic DNAs, complementary DNAs, and HEK293-expressed variants of altogether 19 mammalian species. The between species comparison reveals that the human-specific Gly38Ser polymorphism evolved under strong positive Darwinian selection, probably in adaptation to specific challenges in the fine-…

EvolutionPopulationBiologyEvolution MolecularGene FrequencyCell Line TumorGenotypeQH359-425AnimalsHumansAlleleeducationGeneAllele frequencyEcology Evolution Behavior and SystematicsGenetic associationGeneticsMammalseducation.field_of_studyPolymorphism GeneticHeterozygote advantageLong QT SyndromeGenetics PopulationEvolutionary biologyPotassium Channels Voltage-GatedGenomic imprintingResearch ArticleBMC Evolutionary Biology
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Transnational Political Activities of the Swedish Finn Youth Organization

2017

This article looks at the Swedish Finn Youth Organization’s transnational political activities, and how they have developed. In the beginning, the youth organization modelled itself after its mother organization and joined the Finnish Expatriate Parliament (FEP), which made its participation in transnational practices easy. The case study of the Swedish Finn Youth Organization in Stockholm, Sweden, demonstrates that if the younger generation is given an opportunity to establish and govern their own associations, new forms of organization can be expected. The younger generation has distinguished itself from the older generation’s associations by cooperating with other minorities and taking m…

ExpatriateParliamentmedia_common.quotation_subjectstrategic action fieldlcsh:Colonies and colonization. Emigration and immigration. International migration0507 social and economic geographymigrant associationsthe finnish expatriate parliamentFinnish Expatriate ParliamentPoliticslcsh:HT51-1595Political science050602 political science & public administrationTransnationalismtransnationaalisuusmedia_commonGovernmenttransnationalism05 social sciencesGender studies0506 political scienceMulticulturalismlcsh:JV1-9480lcsh:Communities. Classes. RacesYouth organizationyounger generation050703 geographyNordic Journal of Migration Research
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A Latent State-Trait Analysis of Implicit and Explicit Personality Measures

2005

Abstract. Explicit personality measures assess introspectively accessible self-descriptions. In contrast, implicit personality measures assess introspectively inaccessible processes that operate outside awareness. However, for both kinds of trait measures, the effect of the situation in which the assessment takes place should be as small as possible. The present study aims at quantifying possible systematic occasion-specific effects on implicit measures (Implicit Association Test) and explicit measures (self-report ratings) of extraversion and anxiety by means of a latent state-trait analysis. This analysis revealed that - as desired for personality assessment - all four measures capture m…

Extraversion and introversionmedia_common.quotation_subjectImplicit-association testmedicineAnxietyPersonalityImplicit attitudemedicine.symptomPersonality Assessment InventoryBig Five personality traitsPsychologySocial psychologyApplied PsychologyCognitive psychologymedia_commonImplicit personality theoryEuropean Journal of Psychological Assessment
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Alexithymia and the implicit self-concept of extraversion in women

2016

Abstract Findings from studies using self-reports suggest a negative association between the personality traits of alexithymia and extraversion. Self-report measures are assumed to assess aspects of the explicit self-concept of personality. Indirect measures, such as the Implicit Association Test (IAT), were developed to tap into the implicit self-concept of personality. The present study examined for the first time the relationship between self-reported alexithymia and the implicit self-concept of extraversion. The 20-item Toronto Alexithymia Scale and an Implicit Association Test (IAT) assessing extraversion were administered to 86 healthy women along with the NEO Five-factor Inventory (N…

Extraversion and introversionmedicine.diagnostic_testmedia_common.quotation_subject05 social sciencesSelf-conceptImplicit-association testAnhedonia050109 social psychologymedicine.disease050105 experimental psychologyDevelopmental psychologyToronto Alexithymia ScaleAlexithymiamedicinePersonality0501 psychology and cognitive sciencesmedicine.symptomBig Five personality traitsPsychologyGeneral Psychologymedia_commonPersonality and Individual Differences
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