Search results for "ASTER"
showing 10 items of 2223 documents
Pentamidine rescues contractility and rhythmicity in a Drosophila model of myotonic dystrophy heart dysfunction
2015
Up to 80% of individuals with myotonic dystrophy type 1 (DM1) will develop cardiac abnormalities at some point during the progression of their disease, the most common of which is heart blockage of varying degrees. Such blockage is characterized by conduction defects and supraventricular and ventricular tachycardia, and carries a high risk of sudden cardiac death. Despite its importance, very few animal model studies have focused on the heart dysfunction in DM1. Here, we describe the characterization of the heart phenotype in a Drosophila model expressing pure expanded CUG repeats under the control of the cardiomyocyte-specific driver GMH5-Gal4. Morphologically, expression of 250 CUG repeat…
Zinc isotopes in Late Pleistocene fossil teeth from a Southeast Asian cave setting preserve paleodietary information
2020
Significance Dietary habits, especially meat consumption, represent a key aspect in the behavior and evolution of fossil hominin species. Here, we explore zinc (Zn) isotope ratios in tooth enamel of fossil mammals. We show discrimination between different trophic levels and demonstrate that Zn isotopes could prove useful in paleodietary studies of fossil hominin, or other mammalian species, to assess their consumption of animal versus plant resources. We also demonstrate the high preservation potential of pristine diet-related Zn isotope ratios, even under tropical conditions with poor collagen preservation, such as the studied depositional context in Southeast Asia. However, assessing the …
Terres et pierres pour matières de cultures : l'apparition et la diffusion de nouveaux modes et matériaux de construction dans le Nord-Est de la Gaul…
2017
Roman building materials often arose a growing interest through their presence in early contexts, sometimes way before Gallic Wars. Made from natural resources, their final shape corresponds to anthropogenic and cultural constraints. However, even if building materials are not neglected during archaeological excavations, so far they have been considered as playing a minor part in understanding ancient sites. Economical, technical and architectural aspects are regularly mentioned, creating the picture of an exploited « landscape » around the studied areas, but the question of materials as cultural markers witnessing intercultural relations between Rome and Gallic tribes has never really been…
« Dans le goût de l’antique »
2021
L’interet pour le patrimoine universitaire des universites de Besancon et de Dijon nous a recemment conduits a entreprendre un programme de recherche sur le patrimoine pedagogique lie a l’enseignement de l’histoire de l’art et de l’archeologie a l’echelle de notre region Bourgogne - Franche-Comte (voir ici : https://ista.univ-fcomte.fr/projet-scientifique/projet-moulages). Dans l’etude des photographies argentiques diffusees par les maisons parisiennes (telle Giraudon), des plaques photographiques, des ouvrages de litterature specialisee acquis par nos bibliotheques et des collections de moulages en plâtre constituees a la fin du xixe siecle, nous avons mis en relation les collections des e…
Le Vignaud 3, Chemin du Puits Neuf (Langlade, Gard) : du Fontbouisse au Campaniforme : premiers résultats
2008
Excavations at the site of Le Vignaud 3, Langlade, situated at the heart of the Vaunage, have revealed a settlement constructed in dry stone which fits perfectly within the local Fontbouisse tradition (as exemplified at Boussargues, Le Rocher-du-Causse, etc.). As well as being of architectural interest, particularly in relation to the internal organisation of enclosed sites, the site also produced a large number of finds (pottery, lithics, animal bones, etc.) which provide evidence of Fontbouisse culture and Bell Beaker occupation. The stratigraphic evidence relating these two cultures, and the results of the preliminary analysis of the finds, provide new evidence concerning the adoption of…
Disentangling scattered charcoal assemblages for palimpsest dissection: Spatial analyses from El Salt Stratigraphic Unit Xb (Eastern Iberia)
2017
International audience; Disentangling scattered charcoal assemblages for palimpsest dissection: spatial analyses from El Salt Stratigraphic unit Xb (Eastern Iberia)
L'épreuve de longue durée du master « accompagnement et analyse de pratiques professionnelles » vue au travers de la didactique clinique
2019
International audience
La création des Écoles supérieures du professorat et de l'éducation s'inscrit-elle dans un modèle supranational de professionnalisation des enseignan…
2013
À partir des années 1980, la formation des enseignants connaîtra dans de nombreux États de profonds bouleversements. La France n'échappera pas à ce mouvement de " professionnalisation " et comme chacun de ces États, elle le " traduira " à sa manière. Cette originalité s'est manifestée par la création des IUFM (Instituts universitaires de formation des maîtres) au début des années 1990. Elle s'est également manifestée, jusqu'à la réforme dite de " masterisation ", par le fait de prendre en compte de manière singulière la posture des enseignants en formation, notamment le processus de déscolarisation qui accompagne leur professionnalisation. Or il semble que ni la réforme de la masterisation …
Describing knowledge of the domain of risk and catastrophe by the creation of an ontology
2010
We introduce an ontology of the domain of risk and catastrophe. This ontology is a conceptual model for describing knowledge from a set of concepts linked by semantic and taxonomic relations. We propose a conceptual framework which can be used to analyze various types of events, concentrated or dispersed, whether natural, industrial / technological or social. Our approach distinguishes a factual part from a representational one. The factual part describes the terminology used to depict what happened (e.g. 30 died on some bridge). The representational part depicts the standpoints and judgments of the various actors of the system (there has been an accident, a serious accident or catastrophe)…
Analysis of the 2011 Japan's triple disaster from a conceptual ontology of the domain of risk and disaster,
2012
International audience; In this paper, we propose to use the factual part of a conceptual ontology realized in 2009 (Provitolo and al. 2009 a) to analyze the disaster that occurred in Japan on 11 March 2011 and which was characterized by a sequence of earthquake, tsunami and nuclear accident. Many papers, reports, videos and press articles were published, each one providing a wide variety of information. Some fo- cused on the massive earthquake that triggered the devastating tsunami waves along the eastern coast of the Tohoku region while others mainly analyzed the nuclear crisis. The aim of this work is to syn- thesize in visual form information from various sources and to produce differen…