Search results for "ASTERACEAE"
showing 10 items of 209 documents
Crystal Structures and Cytotoxicity of ent-Kaurane-Type Diterpenoids from Two Aspilia Species
2018
A phytochemical investigation of the roots of Aspilia pluriseta led to the isolation of ent-kaurane-type diterpenoids and additional phytochemicals (1⁻23). The structures of the isolated compounds were elucidated based on Nuclear Magnetic Resonance (NMR) spectroscopic and mass spectrometric analyses. The absolute configurations of seven of the ent-kaurane-type diterpenoids (3⁻6, 6b, 7 and 8) were determined by single crystal X-ray diffraction studies. Eleven of the compounds were also isolated from the roots and the aerial parts of Aspilia mossambicensis. The literature NMR assignments for compounds 1 and 5 were revised. In a cytotoxicity assay, 12α-methoxy-ent-kaur-9(11),1…
Sesquiterpenoids in subtribe Centaureinae (Cass.) Dumort (tribe Cardueae, Asteraceae): distribution, (13)C NMR spectral data and biological propertie…
2012
Asteraceae Bercht. & J. Presl is one of the biggest and most economically important plant families. The taxonomy and phylogeny of Asteraceae is rather complex and according to the latest and most reliable taxonomic classification of Panero & Funk, based on the analysis of nine chloroplast regions, the family is divided into 12 subfamilies and 35 tribes. One of the largest tribes of Asteraceae is Cardueae Cass. with four subtribes (Carlininae, Echinopinae, Carduinae and Centaureinae) and more than 2500 species. Susanna & Garcia-Jacas have organized the genera of Centaureinae (about 800 species) into seven informal groups, which recent molecular studies have confirmed: 1. Basal genera; 2. Vol…
Phytochemical analysis ofAchillea ligusticaAll. from Lipari Island (Aeolian Islands)
2016
A complete chemical investigation of Achillea ligustica All. growing at Lipari (Aeolian Island, Sicily) has been carried out. Seventeen metabolites have been isolated and characterised from dichloromethane and methanol extracts of flowers and aerial parts, and GC/MS analyses of petroleum ether extracts was carried out, revealing a composition in sesquiterpenoids similar to those reported for populations from Greece, Sicily and Algeria, showing the presence of (3RS,6RS)-2,6-dimethyl-1,7-octadiene-3,6-diol (1), 2,6-dimethyl-octa-3(E),7-diene-2,6-diol (2), iso-seco-tanapartholide (3) from DCM fraction. In addition from the methanolic extract of the aerial parts, peculiar flavonoid glucuronides…
New prenylhydroquinone glycosides from Phagnalon rupestre.
2001
Three new hydroquinone glycosides were isolated from the MeOH extract of the aerial parts of Phagnalon rupestre. Their structures were elucidated as 1-O-beta-glucopyranosyl-1,4-dihydroxy-2-(3',3'-dimethylallyl)benzene (1), 1-O-beta-glucopyranosyl-1,4-dihydroxy-2-(3'-hydroxymethyl-3'-methylallyl)benzene (2), and 1-O-(4' '-O-caffeoyl)-beta-glucopyranosyl-1,4-dihydroxy-2-(3',3'-dimethylallyl)benzene (3) by spectroscopic methods.
A New Tetrahydrofuran Derivative from the Endophytic Fungus Chaetomium sp. Isolated from Otanthus maritimus
2009
1 A hitherto unidentified endophytic strain of the genus Chaetomium, isolated from the medicinal plant Otanthus maritimus, yielded a new tetrahydrofuran derivative, aureonitolic acid (), along with 5 known natural products, 2 - 6. The structure of 1 was determined by extensive spectroscopic analysis and comparison with reported data. Extracts of the fungus, grown either in liquid culture or on solid rice media, exhibited considerable cytotoxic activity when tested in vitro against L5178Y mouse lymphoma cells. Compounds 2 and 6 showed significant growth inhibition against L5178Y cells with EC50 values of 7.0 and 2.7 μg/mL, respectively, whereas 1 was inactive
Anti-inflammatory and antioxidant activities of Jungia paniculata.
2010
The present study was conducted to evaluate the antioxidant and anti-inflammatory activities of Jungia paniculata (DC.) A. Gray (Asteraceae), used traditionally in Peru. The dry leaves were extracted with methanol, 50% methanol, and water. The anti-inflammatory activity of this plant was studied using in vitro (nitric oxide production in RAW 264.7 macrophages and sPLA(2) inhibition assay) and in vivo (carrageenan-induced paw edema in rats and TPA-induced ear edema in mice) model systems. The antioxidant activity of extracts was studied using three in vitro model systems (DPPH(*) radical-scavenging assay, ABTS(*+) assay, and superoxide radical-scavenging activity). The results have been corr…
Inhibition of Xanthine Oxidase by Phenolic Conjugates of Methylated Quinic Acid
2003
The caffeoyl conjugates of prenylhydroquinone glucoside and of quinic acid, either in the carboxyl-free or carboxymethyl forms, isolated from Phagnalon rupestre (Asteraceae), showed inhibitory activity on lipid peroxidation induced by Fe 2+/ascorbate and by CCl4/NADPH in rat liver microsomes, with IC50 values ranging from 3 to 11 microM. After having demonstrated their effect on the xanthine oxidase-regulated superoxide production, the active compounds were tested for the direct inhibition of this enzyme. Methylated dicaffeoylquinic conjugates competitively inhibited the enzyme and the highest potency was obtained for the 4,5-diester, with an IC50 value of 3.6 microM, nearly ten times lower…
Typification of the Linnaean name Centaurea seridis (Asteraceae)
2014
The genus Centaurea Linnaeus (1753: 909) (Asteraceae) comprises a large number of taxa mainly occurring in the Mediterranean region and southwest Asia (Susanna & Garcia-Jacas 2007). Centaurea seridis Linnaeus (1753: 915) is distributed from south Europe (Spain incl. Balearic Islands, Italy incl. Sicily, France, Albania and Greece) to northwest Africa (Algeria, Morocco and Tunisia). From a nomenclatural standpoint, Centaurea seridis has not been typified (Jarvis 2007: 402). This paper proposes the designation of a lectotype for this Linnaean name, based on the analysis of the protologue and original material.
The chemical composition of the flowers essential oil of Inula crithmoides (Asteraceae) growing in aeolian islands, Sicily (Italy) and its biocide pr…
2021
Essential oils have been used for a long time in several fields of interest. Recently, they have also been applied in the conservation of Cultural Heritage to contrast biodeterioration replacing the most current biocides toxic for humans and environment. Inula crithmoides L. (syn. Limbarda crithmoides (L.) Dumort) is a halophyte species distributed along the Mediterranean coasts and it is used as an edible vegetable since the young leaves or shoots are eaten raw or cooked. Several biological properties have been determined for this plant including antimicrobial activities. In this study the volatile composition of the aerial part of an accession from the Aeolian Islands, Sicily (Italy) is d…
Guaianolides and lignans from the aerial parts of Centaurea ptosimopappa.
2006
The genus Centaurea L. (Asteraceae, tribe Cardueae, subtribe Centaureinae) comprises ca. 600 species distributed in Asia, Europa, North Africa and America (Hickey and King, 1981; Heywood, 1979). Turkish flora numbers 187 species, 114 of which being endemic (Davis, 1975; Davis et al., 1988; Wagenitz et al., 1988; Guner et al., 2000; Duran and Duman, 2000; Turkoglu et al., 2003). Centaurea ptosimopappa Hayek is an endemic species distributed in the Mediterranean and South-Eastern Anatolian regions of Turkey; widespread and locally frequent in the Amanos and Casus mountains (Davis, 1975; Reeves and Adiguzel, 2004). Aerial parts of C. ptosimopappa were collected in Hatay, the Amanos Mountain ab…