Search results for "ATS"
showing 10 items of 6881 documents
Vascular Activity of (-)-Anonaine, (-)-Roemerine and (-)-Pukateine, Three Natural 6a(R)-1,2-Methylenedioxyaporphines with Different Affinities for α1…
2004
We have studied the mechanism of action of three 6a( R)-1,2-methylenedioxyaporphines as vasorelaxant compounds. The alkaloids assayed showed different affinities for the three human cloned alpha (1)-adrenoceptor (AR) subtypes stably expressed in rat-1 fibroblasts, showing lower affinity for alpha(1B)-AR with regard to the alpha(1A)- or alpha(1D)-subtypes. These three natural compounds are more potent inhibitors of [ (3)H]-prazosin binding than of [ (3)H]-diltiazem binding to rat cerebral cortical membranes. As all these alkaloids inhibited noradrenaline (NA)-induced [ (3)H]-inositol phosphate formation in cerebral cortex and rat tail artery, they may be safely viewed as alpha (1)-AR antagon…
A possible structural determinant of selectivity of boldine and derivatives for the alpha 1A-adrenoceptor subtype.
1996
1. The selectivity of action of boldine and the related aporphine alkaloids, predicentrine (9-O-methylboldine) and glaucine (2,9-O-dimethylboldine) and alpha 1-adrenoceptor subtypes was studied by examining [3H]-prazosin competition binding in rat cerebral cortex. WB 4101 and benoxathian were used as selective alpha 1A-adrenoceptor antagonists. 2. In the competition experiments [3H]-prazosin (0.2 nM) binding was inhibited by WB 4101 and benoxathian. The inhibition curves displayed shallow slopes which could be subdivided into high and low affinity components (pKi = 9.92 and 8.29 for WB 4101, 9.35 and 7.94 for benoxathian). The two antagonists recognized approximately 37% of the sites with h…
Simplification, not “tropicalization”, of temperate marine ecosystems under ocean warming and acidification
2021
Ocean warming is altering the biogeographical distribution of marine organisms. In the tropics, rising sea surface temperatures are restructuring coral reef communities with sensitive species being lost. At the biogeographical divide between temperate and tropical communities, warming is causing macroalgal forest loss and the spread of tropical corals, fishes and other species, termed “tropicalization”. A lack of field research into the combined effects of warming and ocean acidification means there is a gap in our ability to understand and plan for changes in coastal ecosystems. Here, we focus on the tropicalization trajectory of temperate marine ecosystems becoming coral-dominated systems…
Gas-liquid chromatographic analyses
1983
Abstract The gas chromatography of mixtures of n -alkyl acetates (CH 3 COOR, R = C 1 —C 8 ) and methyl esters of aliphatic n -carboxylic acids (R′COOCH 3 , R′ = C 1 —C 8 ) and certain of their monochlorinated derivatives has been studied on Carbowax 20M and SE-30 glass capillary columns under the same operating conditions. The separation of the isomeric monochlorinated esters was complete on Carbowax 20M, whereas on SE-30 the peaks of 6- and 7-chlorooctyl acetates and methyl (ω − 1)- and (ω − 2)-chlorooctanoates and -nonanoates partly overlapped. The complete separation of the mixtures could not be achieved, however, on Carbowax 20M, in spite of the use of various operating conditions. The …
Arbitrage international. Arbitrage multiparties, Groupe de contrats, Clauses compromissoires incompatibles, Consolidation (non)
1991
International audience; (Versailles, 7 mars 1990, Rev. arb. 1991. 326, note Loquin)
Confirmation de l'application du principe de l'efficacité internationale de la clause compromissoire à la transmission de la convention d'arbitrage
2002
International audience; (Cass. 1re civ., 28 mai 2002, inédit, Sté Burkinabe des ciments et matériaux c/ Sté Des ciments d'Abidjan)
Clause compromissoire. Chaîne de contrats translatifs de propriété. Transmissibilité aux acquéreurs subséquents. Exception : preuve de l'ignorance ra…
2001
International audience; (Cass. 1re civ., 6 févr. 2001, Peavey Company c/ Organisme général des fourrages, D.2001.1135, obs. P. Delebecque)
De la transmission et de l'extension de la clause compromissoire : un « grand arrêt » de la première chambre civile de la Cour de cassation
2007
International audience; (Civ. 1re, 27 mars 2007, Sté Alcaltel Business Systems et autre c/ Sté Amkor Technology et autres, Rev. arb. 2007. 247 ; D. 2007. Jur. 2077, note S. Bollée)
Arbitrage international. Clause compromissoire - champs d'application, Chaîne non translative de contrats - Principe de l'effectivité de la clause co…
1996
International audience; (Paris, 22 mars 1995, Sté Aquaboulevard et autres c/ Sté Statinor et autres, inédit)
Société d'avocats. Cession d'action. Prix, Expertise, Article 1843-4 c. civ., Application en matière d'arbitrage
1997
International audience; (Paris, 21 mai 1996, CIP et autres c/ Soulier et autres, Rev. arb., 1996. 225, note Viandier)