Search results for "ATS"
showing 10 items of 6881 documents
Microglial involvement in neuroplastic changes following focal brain ischemia in rats.
2009
The pathogenesis of ischemic stroke is a complex sequence of events including inflammatory reaction, for which the microglia appears to be a major cellular contributor. However, whether post-ischemic activation of microglial cells has beneficial or detrimental effects remains to be elucidated, in particular on long term brain plasticity events. The objective of our study was to determine, through modulation of post-stroke inflammatory response, to what extent microglial cells are involved in some specific events of neuronal plasticity, neurite outgrowth and synaptogenesis. Since microglia is a source of neurotrophic factors, the identification of the brain-derived neurophic factor (BDNF) as…
MitoKATP-channel opener protects against neuronal death in rat venous ischemia.
2005
OBJECTIVE: Mitochondrial adenosine triphosphate-dependent potassium (mitoK ATP ) channels are present in the brain, and several reports have shown their neuroprotective, preconditioning effect against an ischemic insult. The role of mitoK ATP channels in the penumbra area has not been studied thoroughly. In a model of venous ischemia, widespread penumbra-like low flow areas are created, which are susceptible to cortical spreading depression. Thus, we studied effects of mitoK ATP channels on infarct size in this model. METHODS: Male Wistar rats were subjected to two-vein occlusion by photochemical thrombosis of two adjacent cortical veins combined with KCI-induced cortical spreading depressi…
An initial comparative map of copy number variations in the goat (Capra hircus) genome
2010
Abstract Background The goat (Capra hircus) represents one of the most important farm animal species. It is reared in all continents with an estimated world population of about 800 million of animals. Despite its importance, studies on the goat genome are still in their infancy compared to those in other farm animal species. Comparative mapping between cattle and goat showed only a few rearrangements in agreement with the similarity of chromosome banding. We carried out a cross species cattle-goat array comparative genome hybridization (aCGH) experiment in order to identify copy number variations (CNVs) in the goat genome analysing animals of different breeds (Saanen, Camosciata delle Alpi,…
Educación formal e informal en confinamiento : una creciente desigualdad de oportunidades de aprendizaje
2021
El cierre de escuelas en Cataluña para contener los efectos de la COVID-19 obligó a las escuelas y las familias a reaccionar en poco tiempo y sin planificación previa ante un nuevo escenario de enseñanza. Este artículo evalúa el impacto del cierre escolar sobre la desigualdad de aprendizaje entre niños de diferentes contextos sociales en Cataluña. A partir de los datos de una encuesta en línea realizada entre el 26 y el 30 de marzo (n = 35.419) a familias con hijos entre 3 y 18 años, nuestro análisis muestra que las oportunidades de aprendizaje varían significativamente en función de las características del alumnado. Durante el confinamiento, algunas escuelas consiguieron adaptarse a las nu…
Gephyromycin, the first bridged angucyclinone, from Streptomyces griseus strain NTK 14
2005
The new, highly oxygenated angucyclinone gephyromycin was isolated from an extract of a Streptomyces griseus strain. Its unprecedented ether-bridged structure was elucidated by NMR methods and substantiated by single crystal X-ray analysis. The absolute configuration was evidenced by quantum chemical CD calculations. Gephyromycin exhibits glutaminergic activity towards neuronal cells. Furthermore, the known compounds fridamycin E and dehydrorabelomycin were identified.
Latvijas Vēstures Institūta Žurnāls. 2016, Nr. 2 (99)
2016
Valsts kultūrkapitāla fonds
Dual inhibition of cyclooxygenase-1 and 5-lipoxygenase by aerial part of Bupleurum fruticescens methanol extract
2003
The effect of the methanol extract from aerial parts of Bupleurum fruticescens on the release of eicosanoids and hydrolytic enzymes was determined on in vitro cell systems. The extract had a significant effect on 5-lipoxygenase (5-LOX) activity, inhibiting both LTB4 and 5(S)-HETE production with IC50 values of 112 microg/ml and 95 microg/ml, respectively. At concentrations of 200 microg/ml, the extract also inhibited cyclooxygenase-1 (90%) and elastase activities (54%). The 12-LOX activity in intact platelets was not affected; a fact, which suggests that phospholipase A2 (PLA2) activity, is not modified by the extract.
Le vin de Dijon du XIVe au XVIIIe siècle : trajectoire historique d’un cru (presque) disparu
2012
International audience
Les Républicains au Congrès
2015
En 1994, les Républicains élus à la Chambre des représentants promettaient une révolution conservatrice qui devait réduire laplace de l’État fédéral dans la société américaine. Vingt ans plus tard, ce livre dresse le bilan législatif de la longue période de domination républicaine sur la colline du Capitole pour s’interroger sur la portée de la révolution annoncée. En étudiant notamment l’impact des élus du GOP sur la politique budgétaire et les réformes, adoptées ou avortées, de l’État-Provi- dence américain, on observe un écart spectaculaire entre les paroles et les actes. Comment expliquer cet échec relatif de la révolution conservatrice? Quels obstacles éle…
Contrasting Effects of Chronic Anthropogenic Disturbance on Activity and Species Richness of Insectivorous Bats in Neotropical Dry Forest
2022
For prioritizing conservation actions, it is vital to understand how ecologically diverse species respond to environmental change caused by human activity. This is particularly necessary considering that chronic human disturbance is a threat to biodiversity worldwide. Depending on how species tolerate and adapt to such disturbance, ecological integrity and ecosystem services will be more or less affected. Bats are a species-rich and functionally diverse group, with important roles in ecosystems, and are therefore recognized as a good model group for assessing the impact of environmental change. Their populations have decreased in several regions, especially in the tropics, and are threatene…