Search results for "ATZ"
showing 10 items of 256 documents
Ceļš: Latvijas Universitātes Teoloģijas fakultātes teoloģisks un kultūrvēsturisks izdevums, Nr. 59
2009
Finansiālais atbalstītājs - Ziemeļelbas Evaņģēliski luteriskajai baznīca (Vācija)
The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells
2019
Summary: Forkhead box protein P3+ (FOXP3+) regulatory T cells (Treg cells) play a key role in maintaining tolerance and immune homeostasis. Here, we report that a T cell-specific deletion of the transcription factor MAZR (also known as PATZ1) leads to an increased frequency of Treg cells, while enforced MAZR expression impairs Treg cell differentiation. Further, MAZR expression levels are progressively downregulated during thymic Treg cell development and during in-vitro-induced human Treg cell differentiation, suggesting that MAZR protein levels are critical for controlling Treg cell development. However, MAZR-deficient Treg cells show only minor transcriptional changes ex vivo, indicating…
Coarse-grained models of double-stranded DNA based on experimentally determined knotting probabilities
2018
Abstract To accurately model double-stranded DNA in a manner that is computationally efficient, coarse-grained models of DNA are introduced, where model parameters are selected by fitting the spectrum of observable DNA knots: We develop a general method to fit free parameters of coarse-grained chain models by comparing experimentally obtained knotting probabilities of short DNA chains to knotting probabilities that are computed in Monte Carlo simulations, resulting in coarse-grained DNA models which are tailored to reflect DNA topology in the best possible way. The method is exemplified by fitting ideal chain models as well as a bead-spring model with excluded volume interactions, to model …
Assessing Teacher’s Discourse Effect on Students’ Learning: A Keyword Centrality Approach
2020
The way that content-related keywords co-occur along a lesson seems to play an important role in concept understanding and, therefore, in students’ performance. Thus, network-like structures have been used to represent and summarize conceptual knowledge, particularly in science areas. Previous work has automated the process of producing concept networks, computed different properties of these networks, and studied the correlation of these properties with students’ achievement. This work presents an automated analysis of teachers’ concept graphs, the distribution of relevance amongst content-related keywords and how this affects students’ achievement. Particularly, we automatically extracted…
Combined metabolic activity within an atrazine-mineralizing community enriched from agrochemical factory soil
2007
Abstract The main objective of this work was to characterize an atrazine-mineralizing community originating from agrochemical factory soil, especially to elucidate the catabolic pathway and individual metabolic and genetic potentials of culturable members. A stable four-member bacterial community, characterized by colony morphology and 16S rDNA sequencing, was rapidly able to mineralize atrazine to CO 2 and NH 3 . Two primary organisms were identified as Arthrobacter species (ATZ1 and ATZ2) and two secondary organisms (CA1 and CA2) belonged to the genera Ochrobactrum and Pseudomonas, respectively. PCR assessment of atrazine-degrading genetic potential of the community, revealed the presence…
Dzieje organów w kościele parafialnym w Niemczy
2018
Pierwsze wzmianki o organach w kościele parafialnym w Niemczy pochodzą z przełomu XVI i XVII wieku. W latach 1597–1598 niewielki instrument wybudował Abraham Grasse. W 1617 roku ten sam organmistrz postawił nowe organy, liczące sześć głosów w manuale i trzy w pedale. Strawił je pożar w 1633 roku. W 1648 roku do odbudowanego kościoła zakupiono używany pozytyw. W 1725 roku świątynia wzbogaciła się o 20-głosowe organy wybudowane przez Ignatzego Mentzla. Służyły one parafii do 1852 roku, wówczas zamknięto, a następnie rozebrano kościół. Organy znajdujące się w obecnej świątyni pochodzą z 1866 roku i są dziełem Gottfrieda Riemera z Brzegu. Miały pierwotnie 18 głosów i mechaniczną trakturę rejest…
A modified ansatz for explicitly correlated coupled-cluster wave functions that is suitable for response theory
2009
A modified ansatz for explicitly correlated coupled-cluster wave functions with a single correlation factor is set forward. It is based on the fixed amplitude ansatz of Ten-no [Chem. Phys. Lett. 398, 56 (2004)] to which an extra term is added that allows for the explicitly correlated description of singly excited configurations. The new approach has been implemented for coupled-cluster singles and doubles with the aid of automated techniques. Numerical results are presented for vertical excitation energies, and ground and excited state equilibrium distances and harmonic frequencies of diatomics. The new approach is shown to provide a nearly unbiased description of ground and predominantly s…
Hookworm-like eggs in children’s faecal samples from a rural area of Rwanda
2016
Background: Hookworm eggs identification and quantification is usually carried out by Kato-Katz method. However various structures present in the smear may be confused with eggs of such parasites. Objective: To document the presence of structures in Kato-Katz slides that could initially be misinterpreted as hookworm eggs. Method: 497 faecal samples were analysed by Kato-Katz technique, diphasic concentration technique, agar-plate coprocultive and larvae obtained were analysed by PCR and characterized by sequencing. Result: Hookworm-like eggs were found in 159 (32%) of the samples by Kato Katz, finally identified as Caenorhabditis elegans by PCR technique. Conclusion: The diagnosis of human …
Compact two-electron wave function for bond dissociation and Van der Waals interactions: A natural amplitude assessment
2014
Electron correlations in molecules can be divided in short range dynamical correlations, long range Van der Waals type interactions and near degeneracy static correlations. In this work we analyze for a one-dimensional model of a two-electron system how these three types of correlations can be incorporated in a simple wave function of restricted functional form consisting of an orbital product multiplied by a single correlation function $f(r_{12})$ depending on the interelectronic distance $r_{12}$. Since the three types of correlations mentioned lead to different signatures in terms of the natural orbital (NO) amplitudes in two-electron systems we make an analysis of the wave function in t…
Lubāna ledus loba veidotās reljefa formas Atzeles pacēlumā
2022
Grīnbauma, I. 2022. Lubāna ledus loba veidotās reljefa formas Atzeles pacēlumā. Maģistra darbs. Rīga, Latvijas Universitāte, Ģeogrāfijas un Zemes zinātņu fakultāte. Maģistra darbā tika analizētas glaciālās reljefa formas un to izkārtojums Austrumlatvijā, Atzeles pacēlumā, pielietojot 1 m izšķirtspējas digitālo reljefa modeli, kas iegūts no lāzerskenēšanas datiem. Pētījuma teritorija atrodas Fenoskandijas ledus vairoga dienvidaustrumu sektorā, kur uzvirzījās Lubāna ledus lobs. Pētījuma teritorijas glaciālā ģeomorfoloģija nodrošina lielisku iespēju pētīt zemledāja apstākļus un ledus loba plūsmu un iespējamos uzplūdus. Lubāna ledus loba atstātās “pēdas” robežojas no lielizmēra glaciālajiem lin…