Search results for "AUC"

showing 10 items of 1399 documents

Oviposition Cues for a Specialist Butterfly–Plant Chemistry and Size

2008

The oviposition choice of an insect herbivore is based on a complex set of stimuli and responses. In this study, we examined the effect of plant secondary chemistry (the iridoid glycosides aucubin and catalpol) and aspects of size of the plant Plantago lanceolata, on the oviposition behavior of the specialist butterfly Melitaea cinxia. Iridoid glycosides are known to deter feeding or decrease the growth rate of generalist insect herbivores, but can act as oviposition cues and feeding stimulants for specialized herbivores. In a previous observational study of M. cinxia in the field, oviposition was associated with high levels of aucubin. However, this association could have been the cause (b…

0106 biological sciencesIridoid GlycosidesIridoidmedicine.drug_classOvipositionmedia_common.quotation_subjectPlant sizeInsectBiologyGeneralist and specialist speciesMelitaea cinxia010603 evolutionary biology01 natural sciencesBiochemistryArticleSexual Behavior Animalchemistry.chemical_compoundPlantago lanceolataBotanymedicineAnimalsIridoidsGlycosidesPlantagoEcology Evolution Behavior and SystematicsAucubinmedia_commonHerbivoreIridoid glycosidesFeeding BehaviorGeneral MedicineCatalpol010602 entomologychemistryHerbivoreButterflyFemaleButterfliesJournal of Chemical Ecology
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Aggressive interactions between juvenile swordfishes and blue sharks in the Western Mediterranean: a widespread phenomenon?

2019

There are numerous reports of billfishes spearing objects, marine organisms, and even humans. Whether or not this behaviour is intentional and, if so, what is its functional meaning, are open questions. In 2016, an adult blue shark (Prionace glauca) was found to be killed by a juvenile swordfish (Xiphias gladius) in the western Mediterranean. Here we report on three more recent cases involving both species in the same area. In February 2017, an adult male blue shark was found stranded in Garrucha (Spain) with a fragment of a juvenile swordfish’s rostrum (18cm long x 2cm wide at proximal end) inserted in its cranium. In March 2017, an adult pregnant female blue shark was stranded alive on th…

0106 biological sciencesMediterranean climateXiphias gladiusEnvironmental EngineeringAdult femalelethal interaction010604 marine biology & hydrobiologySwordfishRostrumPrionace glaucaZoologyPrionace glaucaAquatic ScienceBiologyPregnant femaleOceanographybiology.organism_classification010603 evolutionary biology01 natural sciencesstrandingJuvenileimpalementGladiuswestern MediterraneanEcology Evolution Behavior and SystematicsMediterranean Marine Science
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Proteomics as a way to identify extra-radicular fungal proteins from Glomus intraradices - RiT-DNA carrot root mycorrhizas

2004

To identify fungal proteins involved in the arbuscular mycorrhizal symbiosis, root-inducing transferred-DNA transformed roots of carrot (Daucus carota L.) were in vitro inoculated with Glomus intraradices. Proteins extracted from the extra-radical fungus were analysed by two-dimensional gel electrophoresis. A fungal reference map displaying 438 spots was set up. Four proteins, among the 14 selected for tandem mass spectrometry analysis, were identified including a NmrA-like protein, an oxido-reductase, a heat-shock protein and an ATP synthase beta mitochondrial precursor. The possible fungal origin of a MYK15-like protein found in mycorrhizal roots was further discussed. This is the first r…

0106 biological sciencesProteomeFungusProteomicsPlant Roots01 natural sciencesApplied Microbiology and BiotechnologyMicrobiologyMass SpectrometryMicrobiologyFungal Proteins03 medical and health sciencesSymbiosisMycorrhizaeElectrophoresis Gel Two-DimensionalMycorrhizaGlomeromycota[SDV.MP] Life Sciences [q-bio]/Microbiology and ParasitologyComputingMilieux_MISCELLANEOUSGel electrophoresis0303 health sciencesFungal proteinEcologybiology030306 microbiologyfungibiology.organism_classificationDaucus carotaArbuscular mycorrhiza[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology010606 plant biology & botanyDaucus carota
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Pactola kuschelisp. nov. (Coleoptera: Curculionidae), a potential cause for the decline of the threatened New Caledonian conifer,Agathis montanade La…

2016

Agathis montana is a conifer endemic to New Caledonia and one of the most threatened (Critically Endangered) plant species of this area. The exact causes of its decline are still unknown. The authors describe the characteristics of A. montana, the history and methodology of population monitoring, and possible factors causing the decline and habitat degradation. In 2014, some twigs showing symptoms suggesting attack by wood-boring insects were collected. From these, imagines of an unknown weevil species belonging to the genus Pactola Pascoe (Eugnomini) were reared. The new species is described as Pactola kuscheli Mazur sp. nov. Colour photographs of the dorsal habitus, line drawings of taxon…

0106 biological scienceseducation.field_of_studyEcologybiologyEcologyWeevilPopulation010607 zoologyAraucariaceaebiology.organism_classification010603 evolutionary biology01 natural sciencesCritically endangeredGenusInsect ScienceAgathisThreatened speciesEndemismeducationAgronomy and Crop ScienceEcology Evolution Behavior and SystematicsAustral Entomology
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Smart Urban Energy Districts and Energy Policies

2018

The deployment of smart cities appears a strategic factor for reducing environmental impact and increasing competitivity of economic systems across the world. Although terminology is similar worldwide, the different political assets and social enviroments largely affect the development models. Drivers indeed are quite different, such as the speed at which transformations take place. As a result, implementation of measures is carried out differently and realizations of smart city projects can be strongly different. Europe, China and U.S.A. approaches are compared in this paper to provide the reader with a broader view about different smart city implementations, with a focus on the electricit…

020209 energymedia_common.quotation_subject02 engineering and technologyEnvironmental economicsEnergy policyTerminologyDevelopment planSoftware deploymentSmart city0202 electrical engineering electronic engineering information engineeringEnvironmental impact assessmentBusinessBureaucracyImplementationmedia_common2018 IEEE Green Technologies Conference (GreenTech)
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Acoustic radiation force impulse point shear wave elastography of the liver and spleen in patients with Gaucher disease type 1: Correlations with cli…

2020

To evaluate the feasibility of acoustic radiation force impulse point shear wave elastography (ARFI-pSWE) of the liver and spleen in patients with Gaucher disease type 1 (GD1), and to assess correlations between organ stiffness and clinico-radiologic data, particularly the GD1 Severity Scoring System (GD-DS3).We retrospectively evaluated the results of ARFI-pSWE as measures of liver and spleen stiffness in 57 patients with GD1. The feasibility of the method was assessed. Correlations between elastography data and clinical data related to the metabolic syndrome, laboratory tests, and GD1-related clinico-radiologic data (bone marrow burden score, GD-DS3) were assessed.ARFI-pSWE provided relia…

0301 basic medicineAdultMalemedicine.medical_specialtyAdolescentEndocrinology Diabetes and MetabolismSpleenDisease030105 genetics & heredityImpulse (physics)BiochemistrySeverity of Illness Index03 medical and health sciencesYoung Adult0302 clinical medicineEndocrinologyGeneticsmedicineHumansIn patientAcoustic radiation forceChildMolecular BiologyAgedRetrospective StudiesGaucher Diseasemedicine.diagnostic_testbusiness.industryReproducibility of ResultsAcousticsMiddle Agedmedicine.diseasePrognosismedicine.anatomical_structureLiverChild PreschoolElasticity Imaging TechniquesFemaleElastographyBone marrowRadiologyMetabolic syndromebusiness030217 neurology & neurosurgeryBiomarkersSpleenFollow-Up StudiesMolecular genetics and metabolism
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Evaluation of treatment response to enzyme replacement therapy with Velaglucerase alfa in patients with Gaucher disease using whole-body magnetic res…

2015

Abstract Objective This was a retrospective data analysis to evaluate the treatment response to enzyme replacement therapy (ERT) with Velaglucerase alfa using whole-body magnetic resonance imaging (MRI). Materials and methods A baseline and follow-up MRI were performed on 18 Gaucher Type 1 patients at an interval of 11.6 months. The MRI score systems determined the Bone-Marrow-Burden (BMB) score, the Dusseldorf-Gaucher score (DGS), and the Vertebra-Disc-Ratio (VDR). The Severity Score Index Type 1 (GD-DS3) was also assessed. Results The baseline MRI medians were: BMB, 7.00; DGS, 3.00; and VDR: 1.70; while, the follow-up MRI medians were: BMB, 7.00; DGS, 3.00; and VDR: 1.73. The baseline GD-…

0301 basic medicineAdultMalemedicine.medical_specialtyWhole body imagingSeverity of Illness Index03 medical and health sciences0302 clinical medicineBone MarrowStatistical significanceSeverity of illnessmedicineHumansEnzyme Replacement TherapyWhole Body ImagingStage (cooking)Molecular BiologyAgedRetrospective StudiesGaucher Diseasemedicine.diagnostic_testbusiness.industryVelaglucerase alfaPlatelet CountMagnetic resonance imagingRetrospective cohort studyCell BiologyHematologyEnzyme replacement therapyMiddle AgedMagnetic Resonance ImagingRecombinant ProteinsSurgery030104 developmental biologyTreatment OutcomeMolecular MedicineGlucosylceramidaseFemaleRadiologybusiness030215 immunologymedicine.drugFollow-Up StudiesBlood cells, moleculesdiseases
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Effects of Study Population, Labeling and Training on Glaucoma Detection Using Deep Learning Algorithms

2020

Author(s): Christopher, Mark; Nakahara, Kenichi; Bowd, Christopher; Proudfoot, James A; Belghith, Akram; Goldbaum, Michael H; Rezapour, Jasmin; Weinreb, Robert N; Fazio, Massimo A; Girkin, Christopher A; Liebmann, Jeffrey M; De Moraes, Gustavo; Murata, Hiroshi; Tokumo, Kana; Shibata, Naoto; Fujino, Yuri; Matsuura, Masato; Kiuchi, Yoshiaki; Tanito, Masaki; Asaoka, Ryo; Zangwill, Linda M | Abstract: PurposeTo compare performance of independently developed deep learning algorithms for detecting glaucoma from fundus photographs and to evaluate strategies for incorporating new data into models.MethodsTwo fundus photograph datasets from the Diagnostic Innovations in Glaucoma Study/African Descent…

0301 basic medicineAginggenetic structuresFundus OculiAfrican descentPopulationBiomedical EngineeringGlaucomaPrimary careNeurodegenerativeoptic disc03 medical and health sciences0302 clinical medicineDeep LearningOpthalmology and OptometryArtificial IntelligencemedicineHumanseducationMild diseaseeducation.field_of_studyReceiver operating characteristicbusiness.industrySpecial IssueDeep learningimagingartificial intelligencemedicine.diseaseeye diseasesOphthalmology030104 developmental biologyglaucomamachine learning030221 ophthalmology & optometryPopulation studyArtificial intelligencebusinessPsychologyAlgorithmAlgorithmsTranslational Vision Science & Technology
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CD36 gene is associated with intraocular pressure elevation after intravitreal application of anti-VEGF agents in patients with age-related macular d…

2017

IF 1.886; International audience; Background: The wet form of age-related macular degeneration (AMD) is characterized by pathological vascularization of the outer retinal layers. The condition responds to treatment with antibodies against vascular endothelial growth factor (VEGF), but the patients receiving such anti-VEGF therapy sometimes show undesirable acute short-term increases in the intraocular pressure (IOP). The cause of this adverse effect is unknown, and here, we are testing a hypothesis that it is related to CD36 gene polymorphisms.Materials and Methods: A group of 134 patients with AMD were given three therapeutic doses of anti-VEGF antibody (ranibizumab) at monthly intervals. …

0301 basic medicineCD36 AntigensMaleVascular Endothelial Growth Factor AIntraocular pressuregenetic structuresreceptorGlaucomaAngiogenesis InhibitorsthrombospondinPolymerase Chain Reactionpolymorphismchemistry.chemical_compound0302 clinical medicineGenotypeGenetics (clinical)Schlemm´s canalVascular endothelial growth factorIntravitreal InjectionsFemalemedicine.drugmedicine.medical_specialtyPolymorphism Single Nucleotide03 medical and health sciencesTonometry Ocular[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyOphthalmologyRanibizumabmedicineHumansAdverse effectIntraocular PressureAgedbusiness.industryGlaucomaRetinalMacular degenerationmedicine.diseaseeye diseasesOphthalmology030104 developmental biologychemistryPediatrics Perinatology and Child Health030221 ophthalmology & optometryWet Macular DegenerationOcular Hypertensionsense organsRanibizumabbusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyOphthalmic genetics
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Autoimmune aspects in glaucoma

2016

The pathogenesis of glaucoma, a common neurodegenerative disease, involves an immunologic component. Studies demonstrate changes of autoantibody concentrations against retinal and optic nerve head antigens in glaucoma patients. Furthermore we found antibody deposits in human glaucomatous retinae in a pro-inflammatory environment. Clinical studies showed up regulated, but also significantly down-regulated autoantibody levels. These antibodies belong to the natural autoimmunity. The upregulation of autoantibodies can be associated with fatal conditions, but several studies demonstrate that natural autoantibodies entail also neuroprotective characteristics and influence the protein expression …

0301 basic medicineGlaucomaAutoimmunityDiseasemedicine.disease_causeNeuroprotectionAutoimmunityPathogenesis03 medical and health sciences0302 clinical medicineAntigenmedicineAnimalsHumansAutoantibodiesPharmacologybusiness.industryAutoantibodyGlaucomamedicine.diseaseNeuroprotection030104 developmental biologyImmunology030221 ophthalmology & optometryBiomarker (medicine)sense organsbusinessEuropean Journal of Pharmacology
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