Search results for "AVAS"

showing 10 items of 428 documents

Automatic segmentation and 3D reconstruction of intravascular ultrasound images for a fast preliminar evaluation of vessel pathologies.

2007

Abstract Intravascular ultrasound (IVUS) imaging is used along with X-ray coronary angiography to detect vessel pathologies. Manual analysis of IVUS images is slow and time-consuming and it is not feasible for clinical purposes. A semi-automated method is proposed to generate 3D reconstructions from IVUS video sequences, so that a fast diagnose can be easily done, quantifying plaque length and severity as well as plaque volume of the vessels under study. The methodology described in this work has four steps: a pre-processing of IVUS images, a segmentation of media–adventitia contour, a detection of intima and plaque and a 3D reconstruction of the vessel. Preprocessing is intended to remove …

Lumen (anatomy)Health InformaticsImaging Three-DimensionalIntravascular ultrasoundmedicineImage Processing Computer-AssistedHumansRadiology Nuclear Medicine and imagingComputer visionSegmentationUltrasonography InterventionalMathematicsRadiological and Ultrasound Technologymedicine.diagnostic_testVector flowbusiness.industryCalculus (dental)3D reconstructionmedicine.diseaseComputer Graphics and Computer-Aided DesignVisualizationStenosisSpaincardiovascular systemBlood VesselsComputer Vision and Pattern RecognitionArtificial intelligencebusinessComputerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
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Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 deficiency reduces leukocyte infiltration into adipose tissue and favors fat deposi…

2009

1525-2191 (Electronic) Journal Article; Obesity is associated with low-grade inflammation and leukocyte infiltration in white adipose tissue (WAT) and is linked to diabetic complications. Semicarbazide-sensitive amine oxidase, also known as vascular adhesion protein-1 (SSAO/VAP-1), is a membrane protein that is highly expressed in adipocytes and is also present on the endothelial cell surface where it is involved in leukocyte extravasation. We studied fat deposition and leukocyte infiltration in WAT of mice with a null mutation in the amine oxidase copper-containing-3 (AOC3) gene encoding SSAO/VAP-1. Both epididymal and inguinal WATs were larger in 6-month-old AOC3-KO males than in age-matc…

MESH: SemicarbazidesAOC3Obesity/geneticsAdipose tissueMESH: Flow CytometryWhite adipose tissueInbred C57BLMESH: Mice KnockoutTransgenicMiceLeukocytesMESH: ObesityMESH: AnimalsMice KnockoutAmine oxidase (copper-containing)food and beveragesNatural killer T cellFlow CytometryLeukocyte extravasationSemicarbazidesCell Adhesion Molecules/*deficiency/*geneticsAdipose TissueMESH: Cell Adhesion MoleculesLeukocytes/*physiologyAmine Oxidase (Copper-Containing)medicine.symptomInfiltration (medical)MESH: Adipose Tissuemedicine.medical_specialtyMESH: Mice TransgenicKnockoutMice TransgenicInflammation[SDV.BC]Life Sciences [q-bio]/Cellular BiologyBiologyMESH: Monoamine OxidasePathology and Forensic MedicineMESH: LeukocytesMonoamine Oxidase/*deficiencyMESH: Mice Inbred C57BLInternal medicinemedicineAnimalsHumansObesityMonoamine OxidaseMESH: Mice[SDV.BC] Life Sciences [q-bio]/Cellular BiologyMESH: HumansAmine Oxidase (Copper-Containing)/*deficiency/*geneticsmedicine.diseaseAdipose Tissue/pathology/*physiologyMice Inbred C57BLEndocrinologyImmunologyMESH: Amine Oxidase (Copper-Containing)Semicarbazides/*pharmacologyCell Adhesion MoleculesRegular Articles
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Dažādo metālisko elementu noteikšana ķērpjos (Parmelia sulcata) Kupravas apkārtnē

2022

Dažādu metālisko elementu noteikšana ķērpjos (Parmelia sulcata) Kupravas apkārtnē. Freimanis R., zinātniskā darba vadītājs Ķīm. mag. Lazarenko V. Bakalaura darbs, 31 lpp., 7 attēli, 9 tabulas, 28 literatūras avoti, 3 pielikumi. Latviešu valodā. Bakalaura darba izstrādes ietvaros, tika analizēts dažādo metālisko elementu saturs lapu ķērpju sugā (Parmelia sulcata) Kupravas apkārtnē. Tika izvēlētas trīs dažādas Kupravas apkārtnes teritorijas – bijušās Kupravas drenu cauruļu rūpnīcas teritorija, Kupravas dzīvojamais rajons, bijušajā militārās armijas daļa un Strautu mežs, kas atrodas ~6 km attālumā no Kupravas, kā tīrāka teritorija. Metālisko elementu saturs ķērpjos (Parmelia sulcata) tika note…

METĀLISKIE ELEMETNIĶĒRPJIKUPRAVAS APKĀRTNEPARMELIA SULCATAINDUKTĪVI SAISTĪTAS PLAZMAS MASSPEKTROMETRSĶīmija
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Plaque and blood vulnerability in ST segment elevation myocardial infarction patients: association between lesion morphology using intravascular ultr…

2013

AIM The purpose of the study was to evaluate associations between iMap intravascular ultrasound tissue characterization of culprit and nonculprit lesions in infarct-related artery and plasma biomarkers during ST segment elevation myocardial infarction (STEMI) and at 10-month follow-up. METHODS AND RESULTS Sixty-three STEMI patients at the time of index hospitalization and 10-month follow-up underwent coronary angiography and intravascular ultrasound with iMap tissue characterization of the culprit artery. Proximal and culprit segments were analyzed. A higher percentage of necrotic tissue in the nonculprit segment was found in patients in the top soluble intercellular adhesion molecule 1 (sI…

MaleAcute coronary syndromemedicine.medical_specialtyTime FactorsMyocardial InfarctionCoronary AngiographyCulpritLesionchemistry.chemical_compoundNecrosisPercutaneous Coronary InterventionPredictive Value of TestsInternal medicineIntravascular ultrasoundPlasminogen Activator Inhibitor 1medicineST segmentHumansMyocardial infarctionProspective StudiesUltrasonography InterventionalAgedmedicine.diagnostic_testbusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseIntercellular Adhesion Molecule-1Coronary VesselsFibrosisPlaque Atheroscleroticmedicine.anatomical_structureTreatment OutcomechemistryPlasminogen activator inhibitor-1CardiologyFemalemedicine.symptomCardiology and Cardiovascular MedicinebusinessBiomarkersArteryCoronary artery disease
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''Assessment of the use of hypolipidemic agents (HAs), mainly statins, in elderly subjects aged 80 years and more in Burgundy: Analysis of 13,211 pat…

2012

Manckoundia, Patrick | Lorenzini, Mathieu | Disson-Dautriche, Anne | Petit, Jean-Michel | Lorcerie, Bernard | Debost, Emmanuel | Menu, Didier | Pfitzenmeyer, Pierre; International audience; ''Only few studies have investigated the use of HA in elderly subjects and there are no data in very elderly subjects. We assessed the prescription of HA and analyzed the relationship between such prescriptions and frailty markers among persons aged 80 and more in an observational study. We recorded the prescriptions for 13,211 patients aged 80-109 years and affiliated to the "Mutualite-Sociale-Agricole (MSA)'' of Burgundy over a 1-month period. The prescription of a HA among all included patients, and t…

MaleAgingHealth (social science)DiseaseCoronary Artery Disease030204 cardiovascular system & hematologylaw.invention0302 clinical medicineRandomized controlled triallawAVERAGE CHOLESTEROL LEVELS030212 general & internal medicineStrokeHypolipidemic AgentsAged 80 and overFibric AcidsOPEN-LABEL3. Good healthCONTROLLED TRIALHypertensionFemaleFranceSTROKEmedicine.drugmedicine.medical_specialtyAdrenergic beta-AntagonistsDrug Prescriptions03 medical and health sciencesPeripheral Arterial DiseaseDiabetes mellitusInternal medicinemedicineDiabetes MellitusHumansCORONARY-HEART-DISEASEMedical prescriptionCARDIOVASCULAR EVENTSMORTALITY''Polypharmacybusiness.industryMORTALITY[SCCO.NEUR]Cognitive science/NeuroscienceCardiovascular Agentsmedicine.disease''CORONARY-HEART-DISEASEPRAVASTATINPhysical therapyPolypharmacyRISK-FACTORSObservational studyGeriatrics and GerontologyHydroxymethylglutaryl-CoA Reductase InhibitorsbusinessPRIMARY PREVENTIONGerontologyPravastatinPlatelet Aggregation Inhibitors
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SARS CoV2 infection _The longevity study perspectives

2021

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MaleAgingssRNA single-stranded RNARFLP restriction fragment length polymorphismHSPs heat shock proteinsReviewPTMs post-translational modificationsSevere Acute Respiratory SyndromeBiochemistryHIV-1 human immunodeficiency virus-1TNF-α tumor necrosis factor-αEC endothelial cells0302 clinical medicineFluAV influenza A virusI insertionMedicineIFN-γ interferon-γDIC disseminated intravascular coagulationPCR Polymerase Chain Reactionmedia_commonAged 80 and overLongevityRBD receptor-binding domainNeurologyLongevity modelMI myocardial infarctionNK natural killerhPIV2 human parainfluenza virus type 2media_common.quotation_subjectResearching genetic basis of resistance and potential pharmacological targetsLongevityDBP diastolic blood pressureNF-Kb nuclear transcription factor kBRANTES regulated upon activation normal T cell expressed and secretedMphi human macrophages03 medical and health sciencesCox 2 cyclooxygenase 2ORF open reading framePT prothrombin timeSettore MED/05 - Patologia ClinicaHumansMolecular BiologyInflammatory genesARDS acute respiratory distress syndromeNO nitric oxideD deletionCpGIs CpG islandsT2DM type 2 diabetes mellitusmedicine.diseaseFDP fibrin degradation products030104 developmental biologySARS CoV2 severe acute respiratory syndrome Coronavirus 2 virusImmunologyBMI body max indexItalian nonagenarians/centenariansRSV respiratory syncytial virusComplication030217 neurology & neurosurgeryMAPK mitogen-activated protein kinaseIP-10 IFN-γ -Inducible Protein 1040301 basic medicineAT1R activity of angiotensin 1 receptorsDCs dentritic cellsSSCP single strand conformation polymorphismACE/DD polymorphism of the angiotensin converting enzymeFGF21 fibroblast growth factor 21TLR4 toll-like receptor 4NAD nicotinamide adenine dinucleotideACE angiotensin-I converting enzymeAT2R activity of angiotensin 2 receptorsCOVID-19 Coronavirus disease 2019Respiratory distressACE2 angiotensin converting enzyme 2MKP-1 mitogen-activated protein kinase phosphatase-1 ()PD protease domainSNP single nucleotide polymorphismEH essential hypertensionTNFR tumor necrosis factor receptorINR international normalized ratio of the prothrombin timePAI-1 plasminogen activator inhibitor-1Ang angiotensinLPS lipopolysaccharideMCP1 monocyte chemoattractant protein-1medicine.symptomaPTT partial thromboplastin timeBiotechnologyDUSP1 dual specificity phosphatase 1Coronavirus disease 2019 (COVID-19)PC prostate cancerRAS renin-angiotensin aldosterone systemCCR5Δ32 genetic variant of chemokine receptorCOVID-19 Researching genetic basis of resistance and potential pharmacological targets Italian nonagenarians/centenarians Longevity modelAsymptomaticSARS-1 severe acute respiratory syndrome virus 1SIRT-1 Sirtuin 1Th1 t-helper lymphocyte type 1Immune systemROS reactive oxygen speciesTGF-β transforming growth factor betaET-1 endothelin-1ComputingMethodologies_COMPUTERGRAPHICSADAM-17 metallopeptidase domain 17business.industrySARS-CoV-2SBP systolic blood pressureCOVID-19HDACs histone deacetylasesComorbidityImmune Systembusiness5-LO lipoxygenase 5Ageing Research Reviews
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Role of S128R polymorphism of E-selectin in colon metastasis formation.

2007

The extravasation of cancer cells is a key step of the metastatic cascade. Polymorphisms in genes encoding adhesion molecules can facilitate metastasis by increasing the strength of interaction between tumor and endothelial cells as well as impacting other properties of cancer cells. We investigated the Ser128Arg (a561c at the nucleotide level) polymorphism in the E-selectin gene in patients with metastatic colon cancer and its functional significance. Genotyping for a561c polymorphism was performed on 172 cancer patients and on an age-matched control population. The colon cancer group was divided into groups with (M+) and without observable metastasis (M−). For in vitro functional assays, …

MaleCancer ResearchColorectal cancerBiologyArginineTransfectionMetastasise-SELECTIN; COLON CANCER METASTASISSettore BIO/13 - Biologia ApplicataCell MovementE-selectinmedicineCell AdhesionSerineTumor Cells CulturedHumansNeoplasm MetastasisPolymorphism GeneticCell adhesion moleculeCancerTransfectionMiddle Agedmedicine.diseaseExtravasationColon Carcinoma E-Selectin Metastasis PolymorphismPhenotypeOncologyImmunologyCancer cellColonic NeoplasmsCancer researchbiology.proteinFemaleE-SelectinSignal TransductionInternational journal of cancer
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Effect of the surface charge of liposomes on their uptake by angiogenic tumor vessels

2003

Recently, cationic liposomes have been shown to preferentially target the angiogenic endothelium of tumors. It was the aim of our study to investigate the influence of liposomal surface charge on the uptake and kinetics of liposomes into solid tumors and tumor vasculature. Experiments were performed in the amelanotic hamster melanoma A-Mel-3 growing in the dorsal skinfold chamber preparation of male Syrian golden hamsters. Fluorescently labeled liposomes with different surface charge were prepared. Accumulation of i.v. injected liposomes was assessed by quantitative intravital fluorescence microscopy of tumor and surrounding host tissue. The histological distribution of liposomes was analyz…

MaleCancer ResearchEndotheliumSurface PropertiesMelanoma ExperimentalBiologyDrug Delivery SystemsCationsCricetinaeTumor Cells CulturedmedicineFluorescence microscopeAnimalsTissue DistributionCationic liposomeLiposomeMesocricetusNeovascularization PathologicExtravasationmedicine.anatomical_structureOncologyInjections IntravenousLiposomesDrug deliveryImmunologyBiophysicsDiffusion Chambers CultureEndothelium VascularDrug carrierBlood vesselInternational Journal of Cancer
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Uncommon Presentations of Non-Hodgkin’s Lymphoma

2003

MaleCancer ResearchPathologymedicine.medical_specialtyLymphoma B-CellProstate biopsyBiopsyDiagnosis DifferentialProstatemedicineHumansProstate diseaseAgedIntravascular large B-cell lymphomaKidneymedicine.diagnostic_testbusiness.industryProstateProstatic Neoplasmsmedicine.diseaseNon-Hodgkin's lymphomamedicine.anatomical_structureOncologyImmunohistochemistrybusinessKidney diseaseJournal of Clinical Oncology
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Late neointimal tissue growth behind the stent after intravascular gamma-radiation.

2003

To determine the nature of the changes of the vascular wall after intravascular brachytherapy in stented arteries leading to incomplete stent apposition.Stents were implanted in the infrarenal aortas of rabbits, and gamma-intravascular brachytherapy (18 Gy) or a sham radiation procedure was immediately implemented. The arteries were harvested at 6 months for histologic analyses.The external elastic lamina area, as well as the vascular wall area behind the stent, were significantly greater in irradiated vs. control arteries (8.94 +/- 0.68 mm2 vs. 6.87 +/- 0.40 mm2 [p0.001] and 1.56 +/- 0.13 mm2 vs. 0.72 +/- 0.07 mm2 [p0.001], respectively). The ratio of the intimal area behind the stent rela…

MaleCancer Researchmedicine.medical_specialtymedicine.medical_treatmentBrachytherapyBrachytherapyConstriction PathologicConstrictionRestenosismedicine.arterymedicineAnimalsRadiology Nuclear Medicine and imagingAorta AbdominalAortaRadiationγ radiationbusiness.industryStentIncomplete stent appositionmedicine.diseaseOncologyIntravascular brachytherapyGamma RaysStentsRadiologyRabbitsbusinessTunica IntimaInternational journal of radiation oncology, biology, physics
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