Search results for "AVAS"

showing 10 items of 428 documents

Pravastatin reverses the membrane cholesterol reorganization induced by myocardial infarction within lipid rafts in CD14(+)/CD16(-) circulating monoc…

2012

International audience; Large numbers of monocytes are recruited in the infarcted myocardium. Their cell membranes contain cholesterol-rich microdomains called lipids rafts, which participate in numerous signaling cascades. In addition to its cholesterol-lowering effect, pravastatin has several pleiotropic effects and is widely used as secondary prevention treatment after myocardial infarction (MI). The aim of this study was to investigate the effects of pravastatin on the organization of cholesterol within monocyte membrane rafts from patients who had suffered myocardial infarction. Monocytes from healthy donors and acute MI patients were cultured with or without 4μM pravastatin. Lipid raf…

AdultMalemedicine.medical_specialtyStatinmedicine.drug_classCD14[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionCaveolin 1Lipopolysaccharide Receptors030204 cardiovascular system & hematologyCD16GPI-Linked ProteinsMonocytes03 medical and health scienceschemistry.chemical_compound0302 clinical medicineCaveolaeInternal medicinemedicineHumansMolecular BiologyLipid raftCells Cultured030304 developmental biologyPravastatin0303 health sciencesCholesterolMonocyteAnticholesteremic AgentsReceptors IgGstatinCell BiologyMiddle Aged3. Good healthlipid raftEndocrinologymedicine.anatomical_structureCholesterolmyocardial infarctionchemistryGene Expression RegulationImmunologycaveolaemonocyteFemalelipids (amino acids peptides and proteins)[SDV.AEN]Life Sciences [q-bio]/Food and NutritionPravastatinmedicine.drug
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Statin therapy and plasma coenzyme Q10 concentrations—A systematic review and meta-analysis of placebo-controlled trials

2015

Statin therapy may lower plasma coenzyme Q10 (CoQ10) concentrations, but the evidence as to the significance of this effect is unclear. We assessed the impact of statin therapy on plasma CoQ10 concentrations through the meta-analysis of available RCTs. The literature search included selected databases up to April 30, 2015. The meta-analysis was performed using either a fixed-effects or random-effect model according to I(2) statistic. Effect sizes were expressed as weighted mean difference (WMD) and 95% confidence interval (CI). The data from 8 placebo-controlled treatment arms suggested a significant reduction in plasma CoQ10 concentrations following treatment with statins (WMD: -0.44 μmol/…

AdultMalemedicine.medical_specialtyUbiquinoneAtorvastatinPharmacologyPlaceboGastroenterologychemistry.chemical_compoundDouble-Blind MethodInternal medicineHumansMedicineRosuvastatinClinical significanceAgedRandomized Controlled Trials as TopicPharmacologyCoenzyme Q10business.industryMiddle AgedPlacebo EffectConfidence intervalchemistrySimvastatinCase-Control StudiesFemaleHydroxymethylglutaryl-CoA Reductase InhibitorsbusinessPravastatinmedicine.drugPharmacological Research
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Surgical Treatment of Extravasation Injuries

2005

The authors present their experience of treating anti-cancer drug extravasation by means of a composite surgical technique that consists of infiltration with physiological solution and hyaluronidase and subsequent manual aspiration of solutes alternated with profuse irrigation of the infiltrated area. In the immediate post-op we carry out a medical therapy that consists of calciparine and topic antibiotic and/or steroid creams. Since the year 2000 this technique has been used on 25 patients. We have had neither complications nor scars. Copyright 2005 Wiley-Liss, Inc Surgical treatment of extravasation injuries. Napoli P, Corradino B, Badalamenti G, Tripoli M, Vieni S, Furfaro MF, Cordova A,…

AdultMalemedicine.medical_specialtyantiblastictreatment KeyWords Plus:ANTITUMOR AGENTSextravasation injury; antiblastic; prevention; treatmentANTITUMOR AGENTS; APPROPRIATE MANAGEMENT; TISSUE EXTRAVASATION; HYALURONIDASE [Author Keywords]Drug ExtravasationTherapeutic irrigationScarsAntineoplastic AgentsTISSUE EXTRAVASATIONAPPROPRIATE MANAGEMENTCicatrixpreventionBiopsymedicineHumansCalciparineAuthor Keywords:extravasation injurySurgical treatmentTherapeutic IrrigationAgedRetrospective Studiesmedicine.diagnostic_testbusiness.industryBiopsy NeedleGeneral MedicineHYALURONIDASEMiddle Agedmedicine.diseaseHandExtravasationSurgeryAnti-Bacterial Agentsanticancer drugsTreatment OutcomeOncologyAnesthesiaSurgeryFemalemedicine.symptombusinessInfiltration (medical)Extravasation of Diagnostic and Therapeutic Materials
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The value of N-terminal fragment of brain natriuretic peptide and tissue inhibitor of metalloproteinase-1 levels as predictors of cardiovascular outc…

2008

Aims We sought to determine the association between two major biomarkers, the inactive N-terminal fragment of brain natriuretic peptide (NT-proBNP) and tissue inhibitor of metalloproteinase-1 (TIMP-1) and long-term cardiovascular outcomes in a cohort of subjects who had a myocardial infarction or unstable angina 3–36 months previously. Methods and results Plasma NT-proBNP and TIMP-1 were measured in a nested case control study of 250 randomly matched subject pairs enrolled in the long-term intervention with pravastatin in ischaemic disease (LIPID) and LIPID extended follow-up studies. Cases ( n = 250) were defined as those who had a cardiovascular death, non-fatal myocardial infarction or s…

AdultMalemedicine.medical_specialtymedicine.drug_classMyocardial InfarctionCoronary AngiographyGastroenterologyLeukocyte CountRisk FactorsInternal medicineNatriuretic Peptide BrainmedicineNatriuretic peptideHumansAngina UnstableAgedPravastatinTissue Inhibitor of Metalloproteinase-1Framingham Risk Scorebusiness.industryAnticholesteremic AgentsCase-control studyOdds ratioMiddle AgedPrognosisBrain natriuretic peptidePeptide FragmentsC-Reactive ProteinEndocrinologyQuartileCase-Control StudiesNested case-control studyFemaleCardiology and Cardiovascular MedicinebusinessBiomarkersPravastatinmedicine.drugEuropean Heart Journal
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Intravascular ultrasound detected classification of coronary lesions as a predictor of dissections after balloon angioplasty.

1996

Dissection after balloon angioplasty of coronary arteries may give rise to an unfavourable early outcome. Compared with coronary angiography, intravascular ultrasound (IVUS) allows more detailed characterisation of dissections. We investigated the incidence and type of dissections after balloon angioplasty in calcified coronary lesions. IVUS was performed in 43 patients with 48 lesions before and after percutaneous balloon angioplasty. Significant calcification was defined as an arc of more than 90 degrees with typical acoustic shadowing. Dissections were classified as type A when the media was not involved by the dissection and as type B when media involvement had occurred. In the group wi…

AdultMalemedicine.medical_specialtymedicine.medical_treatmentBalloonCoronary AngiographyCoronary artery diseaseInternal medicineAngioplastyIntravascular ultrasoundmedicineHumansRadiology Nuclear Medicine and imagingAngioplasty Balloon CoronaryCardiac imagingUltrasonography InterventionalAgedmedicine.diagnostic_testbusiness.industryCalcinosisMiddle Agedmedicine.diseaseCoronary VesselsCoronary arteriesDissectionmedicine.anatomical_structureCardiologyFemaleRadiologyCardiology and Cardiovascular MedicinebusinessTunica MediaCalcificationInternational journal of cardiac imaging
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Facilitated neurogenic inflammation in unaffected limbs of patients with complex regional pain syndrome.

2003

Pain, edema, increased skin temperature, reddening and trophic changes characterize complex regional pain syndrome (CRPS). Recently, we have been able to show facilitated neurogenic inflammation on the affected limb. In the current study unaffected limbs were examined after resolution of the CRPS symptoms to assess possible generalized changes predisposing to CRPS. In 12 patients and in 12 healthy volunteers dermal microdialysis in combination with electrical C-fiber stimulation was employed to induce neuropeptide release. Dialysate protein concentration and axon reflex vasodilation were measured. Neither in patients nor in controls did electrical stimulation lead to protein extravasation, …

AdultMicrodialysisVasodilationStimulationEdemamedicineHumansNeurogenic inflammationbusiness.industryGeneral NeuroscienceNeuropeptidesExtremitiesMiddle Agedmedicine.diseaseExtravasationElectric StimulationVasodilationComplex regional pain syndromeAnesthesiaAxon reflexFemaleDisease Susceptibilitymedicine.symptomNeurogenic InflammationbusinessComplex Regional Pain SyndromesNeuroscience letters
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Intravascular volume therapy in adults guidelines from the association of the scientific medical societies in Germany

2016

No abstract available.

Adultmedicine.medical_specialtyCritical CareHypovolemiaMEDLINEMedizinBlood volumelaw.inventionLactated ringers solution03 medical and health sciences0302 clinical medicineRandomized controlled trial030202 anesthesiologylawGermanymedicineIntravascular volume statusHumansddc:610Intensive care medicineBlood VolumeElective cesarean sectionbusiness.industryCentral venous pressure030208 emergency & critical care medicine3. Good healthAnesthesiology and Pain MedicineFluid Therapybusiness
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Android ĢIS lietotnes izstrāde

2015

Ilmāra Svilsta kvalifikācijas darbā „Android ĢIS lietotnes izstrāde” ir izstrādāta lietotne Android operētājsistēmas atbalstītām ierīcēm. Lietotne tika izstrādāta divu cilvēku grupā, izmantojot „Agile” metoloģiju. Šajā darbā tiek aprakstīts Ilmāra Svilsta projekta darba gaita un sasniegtie rezultāti. Lietotnes mērķis ir atvieglot un padarīt ceļojumu, pārgājienu vai vienkārši ikdienas pastaigu interesantāku un neaizmirstamāku. Lietotne attēlo lietotāja izveidotos punktus uz kartes, kā arī attēlo lietotāja nostaigāto ceļu. Lietotni ir viegli lietot, un tā ir paredzēta jebkuram, kam ir mobilā ierīce ar Android operētājsistēmu. Lietotne ir izstrādāta Android studio vidē, pārsvarā izmantojot Jav…

AgileAndroidDatorzinātneJavascriptGISJava
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Dzelzceļš kā ainavas pārmaiņu virzītājspēks: Suntažu – Ērgļu posms

2015

Bakalaura darba „Dzelzceļš kā ainavas pārmaiņu virzītājspēks: Suntažu – Ērgļu posms” galvenais mērķis ir izvērtēt dzelzceļu kā ainavas veidotāju un pārmaiņu virzītājspēku Suntažu – Ērgļu posmā no 1930. gada līdz mūsdienām. Darbā aprakstīti ainavas pārmaiņu virzītājspēki un pieejamība kā viens no galvenajiem ainavas pārmaiņu virzītājspēkiem. Tajā sniegts ieskats par dzelzceļu vēsturi Latvijā, aprakstīta Rīgas – Ērgļu dzelzceļa līnijas izveide un nozīme. Ar izveidoto karšu palīdzību veikta ainavas pārmaiņu analīze Suntažu – Ērgļu posmā. Tiek aplūkota arī mūsdienu ainava Suntažu – Ērgļu posmā.

Ainavas pārmaiņu virzītājspēkiĢeogrāfijaSuntažiDzelzceļšAinavas pārmaiņasPieejamība
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Zvaigžņotā Debess: 2017, Pavasaris (235)

2017

Contents: “ZVAIGŽŅOTĀ DEBESS” FORTY YEARS AGO: E.Mūkins. Clouds of Venus: Structure and Composition (abridged) ; J.Miezis. 3rd All-union Young Astronomers Gathering (abridged) ; DEVELOPMENTS in SCIENCE: K.Schwartz. New Discoveries in the Milky Way ; DISCOVERIES: I.Eglītis. Small Planets Get Latvian Names ; I.Pundure. Earth-mass World Revealed around Proxima Centauri ; SPACE RESEARCH and EXPLORATION: J.Jaunbergs. Mysteries of Saturn’s Clouds ; A.Slavinskis. Contribution of Estonian Student Satellite Programme ESTCube to Largest Challenges for Humanity ; R.Misa. Impossible Engine that Is likely Possible ; I.Pundure. ESO VLT to Search for Planets in Alpha Centauri System ; EARTH and COSMOS: J.…

Akadēmiķim Oļģertam Dumbrājam – Artura Balklava balva 2017Kosmologs un matemātiķis abats Žoržs LemetrsStarptautiskā matemātikas olimpiāde 2015 – uzdevumu atrisinājumiErnestam Ābelem – 110Pasaules laiks UTC 31.XII 2016. liekā sekunde un LU AI atompulkstenisAsteroīdi – Saule EglitisZemes masas citplanēta Proxima bDzinējs EmDriveIgaunijas Studentu satelītu programma ESTCubeZemes vulkānismsLU Astronomiskais tornis – trešā desmitgadePiena Ceļa galaktika – struktūraSeminārs “Ērglis 2016” MazsalacāESO VLT – planētas Centaura Alfas sistēmāMārīte Eglīte (1951-2016)Vidējās masas melnā cauruma kandidātsTiho Brahe Vēnas salāDebess spīdekļi – 2017.gada pavasarisAgrim J. Kalnājam – 80Nozīmīgākie sasniegumi Latvijas zinātnē 2016:NATURAL SCIENCES::Physics::Astronomy and astrophysics [Research Subject Categories]Saturns – atmosfēraĶīnas nesējraķete CZ-5Mārim Ābelem – 80Zvaigžņotais visums grafikas mākslāIzstāde LU Bibiliotēkā – ar Latviju saistīti asteroīdu nosaukumi
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