Search results for "Absolut"

El «Poema del otoño», de Rubén Darío, consolación de la poesía

2017

El trabajo insiste en el carácter fundacional de la obra de Darío en la poesía hispana debido, entre otras razones, a su poética especialmente dialogante. Poesía humanamente docta y erudita, el «Poema del otoño» pretende otorgar consuelo ante la idea de la muerte. En un contexto secularizado, Darío busca dar cuerpo a un nuevo absoluto, un arte que venza tiempo y espacio. La consolatio asume el tópico del carpe diem, pues el goce de la carne, como la contemplación de la belleza del mundo, como el placer del canto, no solo son experiencias sensibles, sino también simbólicas, que permiten intuir o recordar el orden íntegro y armónico del universo. This work focuses in the foundational role of …

J. V. Foix i la ironia romàntica

2016

Resum: L’article es basa en el convenciment que la comprensió usual de la ironia no pot ser aplicada a les obres de J. V. Foix, les quals més aviat han de ser enteses en el context de la ironia romàntica tal com va ser concebuda per Friedrich Schlegel i més tard documentada en la investigació d’Ingrid Strohschneider-Kohrs. Es descriu el terme «reflexió» com l’autonegació de l’absolut per a després analitzar alguns poemes en prosa del poeta, en què tal classe d’ironia pot ser identificada. En els escrits de Foix les freqüents metareflexions sobre poesia o pintura fan aparèixer els textos o els quadres com a il·legibles o dotats d’un gran poder subversiu. Una peça com «El Roc pertús» deconstr…

Talis hominibus fuit oratio qualis vita. Nietzsche y la narración de sí

2015

Ecce Homo certainly is an unconventional autobiography. Both its structure and its contents are in fact quite different from that traditionally adopted. First, in Ecce Homo life and literary production basically coincide; second, in that book Nietzsche deals with an “I” which is not the traditional “subject” of Western philosophy. In this paper I shall argue that in Ecce Homo Nietzsche tries to develop a new kind of subjectivity. In particular, Nietzsche rejects the idea of an unchanging, absolute, substance subject, and sees it as a mobile construction, something that can be described only insofar as it “becomes what it is”, that is, as it consciously reacts to its unavoidable destiny.

Stereochemistry of terpene derivatives. Part 3: Hydrolytic kinetic resolution as a convenient approach to chiral aminohydroxyiminocaranes with local …

2002

Abstract We have developed a stereoselective hydrolytic kinetic resolution process for diastereoisomeric mixtures of epoxyiminocarene intermediates in the presence of ( R , R )-(−)-(salen)Co(III)OAc catalyst, this was applied as the first step in the synthesis of novel chiral aminohydroxyiminocarane derivatives with local anaesthetic activity. The absolute configuration of the product was confirmed by X-ray crystallography.

1D antiferromagnetism in spin‐alternating bimetallic chains

1990

The magnetic and thermal properties of the ordered bimetallic chain CoNi(EDTA)⋅6H2O in the very low‐temperature range are reported. The magnetic behavior does not exhibit the characteristic features of 1D ferrimagnets, but a continuous decrease of χmT towards zero at absolute zero. This 1D antiferromagnetic behavior results from an accidental compensation between the moments located at the two sublattices. This behavior, as well as the specific‐heat results, are modeled on the basis of an Ising‐exchange model that considers both alternating spins and Landé factors, and a zero‐field splitting on the Ni site. Eugenio.Coronado@uv.es ; Fernando.Sapina@uv.es

Acid rearrangment of epoxy-germacranolides and absolute configuration of 1beta, 10alpha-epoxy-salonitenolide

2010

The acid-catalyzed cyclization of mono epoxides of cnicin acetonide (3) was investigated. Several 6,12-eudesmanolides were obtained, and their stereochemistry established by extensive spectroscopic analyses. Chemical correlations also led to the assignment of the absolute configuration of 1beta,10alpha-epoxy-salonitenolide (13), a previously isolated natural product. The cytotoxic activities of some compounds were determined against A549 and MCF-7 tumor cell lines. The esterified germacranolides 2-6 were selectively cytotoxic against the MCF-7 breast cancer cell line.

A New Cacospongionolide Inhibitor of Human Secretory Phospholipase A2 from the Tyrrhenian Sponge Fasciospongia cavernosa and Absolute Configuration o…

1998

A new inhibitor of human secretory phospholipase A2 (PLA2), cacospongionolide E (4a), has been isolated from the Tyrrhenian sponge Fasciospongia cavernosa. The structure was proposed on the basis of spectroscopic data and by chemical transformations. The absolute configuration of cacospongionolides 2a-4a was established using the modified Mosher's method. Cacospongionolide E was the most potent inhibitor toward human synovial PLA2, showing higher potency than the reference compound manoalide and exerting no signs of toxicity on human neutrophils. It showed high activity in the Artemia salina bioassay and moderate toxicity in the fish (Gambusia affinis) lethality assay.

Sesquiterpenoids from the Endophytic Fungus Rhinocladiella similis

2019

Ten new sesquiterpenoid derivatives, rhinomilisins A-J (1-10), along with six known analogues (11-16), were isolated from the mangrove-derived endophytic fungus Rhinocladiella similis. The structures of the new compounds were elucidated by their NMR and MS data, while the absolute configuration of 3 and 6 was determined by X-ray crystallographic analysis and Mosher's method, respectively. All isolated compounds (1-16) were evaluated for their cytotoxicity against the mouse lymphoma cell line L5178Y, and compounds 1, 7, and 15 showed moderate activity with IC50 values of 5.0, 8.7, and 24.4 μM, respectively.

Belicistas vergonzantes

2003

Development and initial validation of the macrophage activation syndrome/primary hemophagocytic lymphohistiocytosis score, a diagnostic tool that dif…

2017

OBJECTIVE: To develop and validate a diagnostic score that assists in discriminating primary hemophagocytic lymphohistiocytosis (pHLH) from macrophage activation syndrome (MAS) related to systemic juvenile idiopathic arthritis. STUDY DESIGN: The clinical, laboratory, and histopathologic features of 362 patients with MAS and 258 patients with pHLH were collected in a multinational collaborative study. Eighty percent of the population was assessed to develop the score and the remaining 20% constituted the validation sample. Variables that entered the best fitted model of logistic regression were assigned a score, based on their statistical weight. The MAS/HLH (MH) score was made up with the i…