Search results for "Absolute"

showing 10 items of 518 documents

Acid Rearrangment of Epoxy-germacranolides and Absolute Configuration of 1β,10α-Epoxy-salonitenolide

2010

The acid-catalyzed cyclization of mono epoxides of cnicin acetonide (3) was investigated. Several 6,12-eudesmanolides were obtained, and their stereochemistry established by extensive spectroscopic analyses. Chemical correlations also led to the assignment of the absolute configuration of 1β,10α-epoxy-salonitenolide (13), a previously isolated natural product. The cytotoxic activities of some compounds were determined against A549 and MCF-7 tumor cell lines. The esterified germacranolides 2–6 were selectively cytotoxic against the MCF-7 breast cancer cell line.

PharmacologyNatural productStereochemistryAbsolute configurationSalonitenolidePlant ScienceGeneral MedicineEpoxyAcetonideCnicinchemistry.chemical_compoundComplementary and alternative medicineBreast cancer cell linechemistryvisual_artDrug Discoveryvisual_art.visual_art_mediumOrganic chemistryCytotoxicityNatural Product Communications
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Neoclerodane Diterpenoids from Scutellaria pontica

1997

Seven novel neoclerodane diterpenoids, scupontins A-G, have been isolated from the Me2CO extract of the aerial parts of Scutellaria pontica (1-7), together with the known neoclerodanes scutalbin A and scutalpin M. Structures 1-7 were established by exhaustive NMR spectroscopic studies and chemical transformations. Scupontins A-D(1-4, respectively) and scupontins E (5)andF(6) possess unusual [(3¢S,3¢¢S)-3¢-[(3¢¢-acetoxybutyryl)oxy]butyryloxy and [(3¢S,3¢¢S,3¢¢¢S)- 3¢-[[3¢¢-[(3¢¢¢-hydroxybutyryl)oxy]butyryl]oxy]butyryl]oxy substituents, respectively, attached to the C-19 position of the neoclerodane framework. In the case of the 6R,7â-dibenzoate derivative 7 (scupontin G) its absolute config…

Pharmacologychemistry.chemical_classificationBicyclic moleculebiologyStereochemistryOrganic ChemistryAbsolute configurationPharmaceutical ScienceEpoxidebiology.organism_classificationAnalytical Chemistrychemistry.chemical_compoundComplementary and alternative medicinechemistryDrug DiscoveryScutellariaMolecular MedicineDiterpeneChirality (chemistry)Derivative (chemistry)LactoneJournal of Natural Products
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Interferon-?? Alone versus Interferon-?? plus Ribavirin in Patients with Chronic Hepatitis C Not Responding to Previous Interferon-?? Treatment

2000

Objective: To study the effects of monotherapy with leucocyte interferon-α (IFNα) versus IFNα + ribavirin in patients with chronic hepatitis C who were nonresponders to previous courses of recombinant or lymphoblastoid IFNα. Design and setting: This was a nonblind randomised study of outpatients at 3 centres in Palermo, Sicily, Italy. Patients and participants: We recruited 72 patients (48 males, 24 females), mean age 48.8 ± 6.6 years (range 31 to 63 years), with biopsy-proven chronic hepatitis C, predominantly genotype lb. Interventions: 24 patients (group A) received IFNα 6MU 3 times weekly for 6 months, and 48 patients (group B) received IFNα 6MU 3 times weekly + ribavirin 1200 mg/day fo…

Pharmacologymedicine.medical_specialtyCombination therapybusiness.industryRibavirinHepatitis C virusAlpha interferonGeneral Medicinemedicine.disease_causeGastroenterologydigestive system diseasesGroup Bchemistry.chemical_compoundchemistryInterferonInternal medicineAbsolute neutrophil countMedicinePharmacology (medical)businessAdverse effectBiotechnologymedicine.drugBioDrugs
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The Phenomenology of Space and Time: Husserl, Sartre, Derrida

2016

The notions of space and time have been a subject of philosophical discussion since antiquity. In modern philosophy, Newton’s concepts of absolute space and absolute time was subject to criticism by empiricists like Berkeley and Hume, who prepared the ground for Einstein and the ideas behind his theories of relativity. In this article, I will consider the concept of space-time from a phenomenological point of view, with particular reference to Jean-Paul Sartre and Jacques Derrida. Sartre presents a phenomenological notion of space as nothingness, and I argue that this notion corresponds closely to Einstein's view, and can be extended to include the notion of time, and hence of space-time. I…

Phenomenology (philosophy)symbols.namesakeSpacetimeNothingPhilosophyAbsolute time and spacesymbolsCriticismEmpiricismModern philosophyEinsteinEpistemology
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Zināšanas izpratne Hēgeļa gara fenomenoloģijā. Hermeneitiskā dialektika

2013

Elektroniskā versija nesatur pielikumus

PhilosophyknowledgeVēsture filozofijaabsolutezināšanaabsolūtaisHēgelisdialecticHeidegersdialektikaHeideggerHegelFilozofija
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The effect of quantum size confinement on the optical properties of PbSe nanocrystals as a function of temperature and hydrostatic pressure

2013

A study based on photoluminescence and absorption measurements as a function of temperature and pressure for PbSe nanocrystals with sizes in the range 3–13 nm reveals the influence of size quantum confinement on the observed variation. In the case of the temperature variation, the effective bandgap changes from showing a positive rate of change to showing a negative one (for a quantum dot 3 nm in diameter), which can be accounted for by incorporating a linear variation of the carrier effective masses into a simple calculation of the exciton ground state in the quantum dot. In the case of the pressure variation, we observe a clear inverse correlation between the absolute value of the pressur…

PhotoluminescenceMaterials scienceCondensed matter physicsBand gapMechanical EngineeringHydrostatic pressureBioengineeringAbsolute value02 engineering and technologyGeneral Chemistry021001 nanoscience & nanotechnology7. Clean energy01 natural sciencesPressure coefficientCondensed Matter::Materials ScienceNanocrystalMechanics of MaterialsQuantum dot0103 physical sciencesGeneral Materials ScienceElectrical and Electronic Engineering010306 general physics0210 nano-technologyAbsorption (electromagnetic radiation)Nanotechnology
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Quantification of spatial inhomogeneity in perovskite solar cells by hyperspectral luminescence imaging

2016

Vacuum evaporated perovskite solar cells with a power conversion efficiency of 15% have been characterized using hyperspectral luminescence imaging. Hyperspectral luminescence imaging is a novel technique that offers spectrally resolved photoluminescence and electroluminescence maps (spatial resolution is 2 micrometer) on an absolute scale. This allows, using the generalized Planck’s law, the construction of absolute maps of the depth-averaged quasi-Fermi level splitting (Δμ), which determines the maximum achievable open circuit voltage (Voc) of the solar cells. In a similar way, using the generalized reciprocity relations the charge transfer efficiency of the cells can be obtained from the…

PhotonMaterials sciencePhotoluminescenceRenewable Energy Sustainability and the Environmentbusiness.industryOpen-circuit voltageEnergy conversion efficiencyHyperspectral imaging02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnology01 natural sciencesPollution0104 chemical sciencesOpticsNuclear Energy and EngineeringEnvironmental ChemistryOptoelectronics0210 nano-technologyLuminescencebusinessAbsolute scalePerovskite (structure)Energy & Environmental Science
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Absolute frequency measurement of rubidium 5S-7S two-photon transitions.

2013

We report the absolute frequency measurements of rubidium 5S-7S two-photon transitions with a cw laser digitally locked to an atomic transition and referenced to an optical frequency comb. The narrow, two-photon transition, 5S-7S (760 nm) insensitive to first order in a magnetic field, is a promising candidate for frequency reference. The performed tests yield the transition frequency with accuracy better than reported previously.

PhysicsAtomic Physics (physics.atom-ph)Absolute frequencyFOS: Physical sciencesPhysics::Opticschemistry.chemical_elementCw laserFirst orderAtomic and Molecular Physics and OpticsPhysics - Atomic PhysicsRubidiumMagnetic fieldTwo-photon excitation microscopychemistryYield (chemistry)Physics::Atomic PhysicsOptical frequency combAtomic physicsOptics letters
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Frequency-modulated atomic force microscopy operation by imaging at the frequency shift minimum: the dip-df mode.

2014

In frequency modulated non-contact atomic force microscopy, the change of the cantilever frequency (Delta f) is used as the input signal for the topography feedback loop. Around the Delta f(z) minimum, however, stable feedback operation is challenging using a standard proportional-integral-derivative (PID) feedback design due to the change of sign in the slope. When operated under liquid conditions, it is furthermore difficult to address the attractive interaction regime due to its often moderate peakedness. Additionally, the Delta f signal level changes severely with time in this environment due to drift of the cantilever frequency f(0) and, thus, requires constant adjustment. Here, we pre…

PhysicsCantileverbusiness.industrySurface PropertiesPID controllerAbsolute valueDerivativeFeedback loopModels TheoreticalMicroscopy Atomic Force530SignalCalcium CarbonateSetpointOpticsbusinessConstant (mathematics)InstrumentationThe Review of scientific instruments
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The growth of atomically rough 4He crystals

1986

We have studied the growth of atomically rough bcc and hcp4He crystals from the superfluid phase for temperaturesT>0.9 K. The growth coefficient displays a temperature dependence which can be represented bym 4 K∝ $$e^{\Delta E/k_B T} $$ . The parameter ΔE is found to be in close agreement with the energy gap of rotons, suggesting that these thermal excitations dominate the growth kinetics. Besides, the absolute value of the growth coefficient depends on crystal orientation, with an anisotropy for the hcp phase of about a factor of 2.5 between the $$\left\{ {10\bar 10} \right\}$$ and {0001} planes.

PhysicsCondensed matter physicsBand gapCondensed Matter::OtherThermodynamicsAbsolute valueCrystal growthCondensed Matter PhysicsElectronic Optical and Magnetic MaterialsSuperfluidityHelium-4Phase (matter)General Materials Scienceddc:530AnisotropyBar (unit)
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