Search results for "Abstract"

Sequential and combined treatment of prolidase deficiency leg ulcers

2010

Background The Authors report a case of chronic cutaneous lesions in a patient affected by prolidase deficiency, a rare disorder inherited through an autosomal recessive gene (50 cases reported ). The enzyme prolidase is widely distributed throughout the body and it is important in the recycling of proline and hydroxyproline. Among the clinical presentations, the most striking manifestation is the skin fragility with leg ulceration (see Table ​Table11) Table 1 Clinical signs of prolidase deficiency The deficiency of the enzyme prolidase is responsible for massive loss of proline in the urine which is estimated to be as high as 3 g/die. The diagnosis is ascertained by iminopeptiduria greater…

P03-010-B - A novel mutation in MEFV gene is not enough

2013

Genotype-phenotype correlation is still challenging in FMF patients especially when the disease is part of a complex autoinflammatory disease.

Effects of atypical antipsychotics on neurocognition in euthymic bipolar patients

2010

International audience; n.a

Mo2021 Predicting Polyp Histology - Development and Validation of an International Simple Endoscopic Classification of Small Colorectal Polyps Using …

2017

An Abstract Generic Framework for Web Site Verification

2008

In this paper, we present an abstract framework for Web site verification which improves the performance of a previous, rewriting-based Web verification methodology. The approximated framework is formalized as a source-to-source transformation which is parametric w.r.t. the chosen abstraction. This transformation significantly reduces the size of the Web documents by dropping or merging contents that do not influence the properties to be checked. This allows us to reuse all verification facilities of the previous system WebVerdi-M to efficiently analyze Web sites. In order to ensure that the verified properties are not affected by the abstraction, we develop a methodology which derives the …

Healthcare associated pathogens in a changing world

2014

In developed countries about 10% of the hospitalizations are complicated by a healthcare-associated infection [1]. Up to 75% of these infections are due to multidrug-resistant organisms (MDROs) [1]. Antimicrobial resistant bacterial infections are associated to higher morbidity, mortality and healthcare costs than those caused by susceptible organisms [1]. The findings of the point prevalence survey in European acute care hospitals published in 2013 by the European Centre for Disease Control and Prevention (ECDC) show large variations between countries and between different regions of the same country, with Italy being allocated within the high-endemic areas for both MRSA and MDROs [2]. Des…

188. Does Cannabis Use Worsen Psychotic Symptom Presentation?

2017

Background: While the relationship between cannabis and psychosis is well established, there is a lack of studies into whether cannabis use is associated with a particular pattern of symptoms at psychosis onset. Moreover, there is much evidence that psychotic experiences are common in the healthy population, and again their relationship with exposure to cannabis has been scarcely studied. We hypothesized that psychopathology in first-episode psychosis patients (FEP), and psychotic experiences in controls, would be qualitatively and quantitatively affected by pattern of cannabis use.

O3.1. ASSOCIATION OF EXTENT OF CANNABIS USE AND ACUTE INTOXICATION EXPERIENCES IN A MULTI-NATIONAL SAMPLE OF FIRST EPISODE PSYCHOSIS PATIENTS AND CON…

2019

Background FEP patients who use cannabis experience more frequent intoxication experiences compared to controls. It is not clear whether this is consequent to patients being more vulnerable to the effects of cannabis use or to their heavier pattern of use. We aimed to determine whether extent of use predicted psychotic-like and euphoric intoxication experiences in FEP patients and controls and whether this differs between groups. Methods We analysed data on lifetime cannabis using patients (n=655) and controls (n=654) across 15 sites from six countries in the EU-GEI study (2010–2015). We used multiple regression to model predictors of cannabis-induced experiences and Factorial ANOVA to dete…

Global health training in paediatric residency programs: the Italian experience

2015

Osservatorio Nazionale Specializzandi Pediatria (ONSP) is an Italian association of residents in paediatrics, and one of its interests is to support paediatric training in developing countries. In 2014, for this purpose, ONSP performed a survey with the aim of describing interest, participation, resources, and obstacles of residents who are involved in global health training within paediatric residency programs. Once the final data were known, an informative brochure was produced for publicizing the results of this survey and the projects that Italian Pediatric Schools have activated in developing countries. 35 of 38 paediatric residency schools (92%) participated in the survey. 67% of them…

Evaluation of early and late histamine release by three standard volume substitutes

2001

Following meta-analysis [1], the use of colloidal solutions in intensive care medicine is under discussion. Although polygeline [2] and human albumin are known to cause histamine release, other substances eg hydroxyethyl starch were thought to be without effect. Histamine release depends on the clinical scenario, concomitant drugs, infusion speed, duration and amount of infusion. However, there is no information about their effect regarding time periods longer than immediate reactions. This study investigated the histamine releasing effects of three plasma substitutes administered and observed over a longer period of time, simulating many of the clinical scenarios.