Search results for "Acer"

showing 10 items of 786 documents

El bienestar del menor por nacer: ¿un interés a ponderar en el acceso a las técnicas de reproducción asistida?

2020

La necesidad de aproximar las legislaciones de los distintos Estados europeos en el ámbito de la reproducción asistida, para evitar el llamado “turismo reproductivo”; así como la conveniencia de realizar una valoración previa de las personas que solicitan ser receptoras de estas técnicas con fines reproductivos, en orden a acercar las distintas formas de filiación, hace que nos planteemos en el presente trabajo la introducción del “bienestar del menor por nacer” como un “interés” más a ponderar para acceder a las técnicas de reproducción asistida. The need to approximate the legislation of the different European States in the field of assisted reproduction, in order to prevent the so-called…

:CIENCIAS JURÍDICAS [UNESCO]UNESCO::CIENCIAS JURÍDICASDerecho CivilDerechos reproductivosWelfare of the unborn childAssisted reproductive technologiesParenting capacityTécnicas de reproducción asistidaReproductive rightsBienestar del menor por nacerCapacidad parental
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El Grand Débat National de Francia : análisis de un proceso participativo multicanal.

2021

En una época de cambios tecnológicos y sociales, la ciudadanía demanda nuevos canales de participación pública. En los últimos tiempos distintos procesos de participación recurren a la opinión ciudadana para adoptar decisiones. El movimiento de los chalecos amarillos desencadenó una ola de protestas en Francia a la que quiso hacerse frente con el Grand Débat National, un proceso participativo multicanal, a distintos niveles administrativos. El estudio de su desarrollo y resultados debe servir para diseñar futuros procesos similares.

:CIENCIAS JURÍDICAS [UNESCO]inequalitya distintos niveles administrativos. El estudio de su desarrollo y resultados debe servir para diseñar futuros procesos similares. Proceso participativochalecos amarillosciudadaníacambios sociales.Grand Débat NationalcitizenryAlvaro En una época de cambios tecnológicos y socialesyellow vestsParticipatory processUNESCO::CIENCIAS JURÍDICASun proceso participativo multicanal2070-8157 22082 Revista Boliviana de Derecho 584568 2021 32 8055250 El Grand Débat National de Francia análisis de un proceso participativo multicanal. Gonzálezla ciudadanía demanda nuevos canales de participación pública. En los últimos tiempos distintos procesos de participación recurren a la opinión ciudadana para adoptar decisiones. El movimiento de los chalecos amarillos desencadenó una ola de protestas en Francia a la que quiso hacerse frente con el Grand Débat Nationalsocial changes. 1064 1089desigualdad
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Abordaje supracerebeloso transtentorial suprameatal a la totalidad de la región mediobasal del lóbulo temporal

2015

La región mediobasal del lóbulo temporal (RMT), por su compleja anatomía y su localización, constituye a día de hoy un reto neuroquirúrgico de primer orden. El desarrollo de la cirugía microquirúrgica de base craneal y los nuevos horizontes de la cirugía endoscópica siguen sin ofrecer un abordaje óptimo para aquellas lesiones asentadas en la totalidad de la RMT (principalmente oncológicas y vasculares). La exposición parcial de la RMT y el compromiso de estructuras neurovasculares no implicadas en la patología a tratar suponen los principales inconvenientes a la hora de plantear el abordaje de dichas lesiones. Las lesiones con frecuencia tumorales, que afectan la totalidad de la RMT, requie…

:CIENCIAS MÉDICAS ::Cirugía ::Neurocirugía [UNESCO]petrosectomía suprameatalregión mediobasal temporalUNESCO::CIENCIAS MÉDICAS ::Cirugía ::Neurocirugíaabordajes neuroquirúrgicossupracerebeloso transtentorial
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Strategies to gain novel Alzheimer’s disease diagnostics and therapeutics using modulators of ABCA transporters

2021

Adenosine-triphosphate-(ATP)-binding cassette (ABC) transport proteins are ubiquitously present membrane-bound efflux pumps that distribute endo- and xenobiotics across intra- and intercellular barriers. Discovered over 40 years ago, ABC transporters have been identified as key players in various human diseases, such as multidrug-resistant cancer and atherosclerosis, but also neurodegenerative diseases, such as Alzheimer���s disease (AD). Most prominent and well-studied are ABCB1, ABCC1, and ABCG2, not only due to their contribution to the multidrug resistance (MDR) phenotype in cancer, but also due to their contribution to AD. However, our understanding of other ABC transporters is limited…

ABCG2 (BCRP)Multitarget inhibitor (PANABC)Broad-spectrum modulatorPolypharmacologyActivationNeurosciences. Biological psychiatry. NeuropsychiatryAmyloid-beta (Aβ / Abeta)ABCA2ABCA5ArticleABCA7InductionABCB1 (P-gp)Pattern analysisDownregulationPET Tracer (PETABC)ABC transporterABCA1 (ABC1)Rational drug design and developmentAlzheimer’s diseaseRC321-571ABCC1 (MRP1)InhibitionFree neuropathology
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Aroniju ogu fitoķīmiskā sastāva izvērtējums

2019

Aroniju ogu fitoķīmiskā sastāva izvērtēšana. Batarāga A. Zinātniskā vadītāja Asoc.prof. Dr. ķīm. Prikšāne A., konsultante Mg.ķīm. Valkovska V. Maģistra darbs, 76 lappuses, 46 attēli, 20 tabulas, 44 literatūras avoti. Latviešu valodā. Darbā analizēts aroniju ogu fitoķīmiskais sastāvs, nosakot kopējo fenolu, flavonoīdu saturu un antiradikālo aktivitāti. Lai pagatavotu analizējamos paraugus, izmantotas gan sasaldētas, gan ţāvētas ogas un kā ekstrahenti – 70 % etanola/ūdens, 10 % glicerīna/etanola un daţādu koncentrāciju un pH vērtību etanola/ūdens/HCl maisījumi. Pēc ultraskaľas veicinātas ekstrakcijas un 1 – 3 nedēļu ilgas macerācijastika noteikts kopējo fenolu saturs, izmantojot FolinCiocalte…

ANTIRADIKĀLĀ AKTIVITĀTEKOPĒJO FENOLU DAUDZUMSARONIJU OGASKOPĒJO FLAVONOĪDU DAUDZUMSMACERĀCIJAĶīmija
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Binding mode analysis of ABCA7 for the prediction of novel Alzheimer's disease therapeutics

2021

Graphical abstract

ATP Adenosine-triphosphateNBD nucleotide binding domainGSH reduced glutathionePolypharmacologyAlzheimer’s disease (AD)ATP-binding cassette transporterHTS high-throughput screeningBiochemistryABCA7Structural BiologyPLIF protein ligand interactionMSD membrane spanning domainPDB protein data bankTM transmembrane helixABC ATP-binding cassetteMultitarget modulation (PANABC)RMSD root mean square distanceABC transporter (ABCA1 ABCA4 ABCA7)Computer Science ApplicationsMOE Molecular Operating EnvironmentPharmacophoreSNP single-nucleotide polymorphismBiotechnologyResearch ArticleBBB blood-brain barrierBiophysicsDrug designComputational biologyBiologyAD Alzheimer’s diseasePET positron emission tomographyIC intracellular helixAPP amyloid precursor proteincryo-EM cryogenic-electron microscopyGeneticsHomology modelingBinding siteRational drug design and developmentComputingMethodologies_COMPUTERGRAPHICSNBD-cholesterol 7-nitro-2-13-benzoxadiazol-4-yl-cholesterolTransporterPSO particle swarm optimizationPET tracer (PETABC)ECD extracellular domainR-domain/region regulatory domain/regionABCA1biology.proteinEH extracellular helixTP248.13-248.65BODIPY-cholesterol 44-difluoro-4-bora-3a4a-diaza-s-indacene-cholesterolComputational and Structural Biotechnology Journal
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Phytosociology and ecology of deciduous forests in Tajikistan (Middle Asia)

2017

Aims: To present the first syntaxonomical classification for the mesophilous deciduous forests of the PamirAlai Mountains in Tajikistan with some remarks on its environmental gradients. Location: Tajikistan. Methods: Altogether 201 relevés were sampled between 2008‒2013 using the seven-degree cover-abundance scale of Braun-Blanquet. They were classified by the modified TWINSPAN method using the four-step interval scale with cutoff levels of 0%, 2%, 5% and 10% and total inertia as a measure of cluster heterogeneity. Diagnostic species were identified using the phi coefficient as a fidelity measure. Detrendended Correspondence Analysis was used to determine the relation between samples, veget…

Acero turkestanici-Juglandion regiae0106 biological sciencesTajikistanEcology (disciplines)phytosociologyMiddle asiaPlant Science010501 environmental sciences010603 evolutionary biology01 natural sciencespopuletea laurifolio-suaveolentisQuerco-Fagetea; syntaxonomysyntaxonomyquerco-fageteavegetation classification0105 earth and related environmental sciencesNerio-TamariceteaMiddle Asiapopulion afghanicaePhytosociologyAgroforestryEcologyPopuletea laurifolio-suaveolentisacero turkestanici-juglandion regiaePamir Alai MtsPamir Alai Mts.GeographyDeciduousPopulion afghanicaedecidous forest
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Achlya spiralis, a new aquatic oomycete with bent oogonial stalks, isolated from the Burgundian region of France

2008

Achlya spiralis sp. nov. was isolated from water samples collected in the river Tille in the Burgundian region of France. The new oomycete is described, illustrated and compared with related species of the genus Achlya. It is characterized by the presence of smooth-walled oogonia that are usually borne on bent or twisted oogonial stalks; mainly monoclinous, androgynous and diclinous antheridial branches and eccentric oospores which generally do not mature or mature after a long period of time. The internal transcribed spacer (ITS) region of its rRNA is comprised of 671 bases. The taxonomic description of this new species, its comparison with related oomycetes and the sequence of the ITS reg…

Achlya spiralisAntheridiaMolecular Sequence DataFresh WaterMicrobiologyDNA AlgalOogoniaRiversGenusDNA Ribosomal SpacerBotanyGeneticsAchlya spiralisCiencias NaturalesInternal transcribed spacerrRNAMolecular BiologyOomyceteMicroscopybiologyITS regionSequence Analysis DNAAchlyaOosporesRibosomal RNAbiology.organism_classificationAchlyaAntheridiumOosporeFrance
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Systematic Analysis of Combined Thrombolysis Using Ultrasound and Different Fibrinolytic Drugs in an in Vitro Clot Model of Intracerebral Hemorrhage.

2021

Adequate removal of blood clots by minimally invasive surgery seems to correlate with a better clinical outcome in patients with intracerebral hemorrhages (ICHs). Moreover, neurotoxic effects of recombinant tissue plasminogen activator have been reported. The aim of this study was to improve fibrinolysis using an intra-clot ultrasound application with tenecteplase and urokinase in our established ICH clot model. One hundred thirty clots were produced from 25 or 50 mL of human blood, incubated for different periods and equipped with drainage, through which an ultrasound catheter was placed in 65 treatment clots for 1 h, randomly allocated into three groups: administration of ultrasound, admi…

Acoustics and UltrasonicsMechanical Thrombolysismedicine.medical_treatmentUltrasonic TherapyBiophysicsTenecteplase030204 cardiovascular system & hematologyIn Vitro Techniques03 medical and health sciences0302 clinical medicineFibrinolytic AgentsFibrinolysismedicineHumansRadiology Nuclear Medicine and imagingThrombolytic TherapyCerebral HemorrhageIntracerebral hemorrhageUrokinaseRadiological and Ultrasound Technologybusiness.industryUltrasoundThrombosisThrombolysismedicine.diseaseCombined Modality TherapyUrokinase-Type Plasminogen ActivatorIn vitroCatheterAnesthesiaTenecteplasebusiness030217 neurology & neurosurgerymedicine.drugUltrasound in medicinebiology
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Long-term monitoring of mrk 501 for its very high energy γ emission and a flare in 2011 october

2012

"As one of the brightest active blazars in both X-ray and very high energy γ -ray bands, Mrk 501, is very useful for" "physics associated with jets from active galactic nuclei. The ARGO-YBJ experiment has monitored Mrk 501 for γ - rays above 0.3 TeV since 2007 November. The largest flare since 2005 was observed from 2011 October and lasted until about 2012 April. In this paper, a detailed analysis of this event is reported. During the brightest γ -ray flaring episodes from 2011 October 17 to November 22, an excess of the event rate over 6σ is detected by ARGO-YBJ in the direction of Mrk 501, corresponding to an increase of the γ -ray flux above 1 TeV by a factor of 6.6 ± 2.2 from its steady…

Active galactic nucleusactive" ["galaxies]Astrophysics::High Energy Astrophysical PhenomenaFluxAstrophysicsAstrophysics::Cosmology and Extragalactic Astrophysics7. Clean energy01 natural sciencesSpectral linelaw.inventionlaw0103 physical sciencesBlazar010303 astronomy & astrophysicsPhysicsindividual (Markarian 501) – galaxies: active – gamma rays: general – radiation mechanisms: non-thermal [BL Lacertae objects]" "general" ["gamma rays]010308 nuclear & particles physicsBL Lacertae objects: individual (Markarian 501) – galaxies: active – gamma rays: general – radiation mechanisms: non-thermalSettore FIS/01 - Fisica SperimentaleAstronomy and AstrophysicsQuasarGalaxyindividual (Markarian 501)" ["BL Lacertae objects]13. Climate actionSpace and Planetary ScienceSpectral energy distributionFlare
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