Search results for "Actic acid"

TISSUE pH-DISTRIBUTION WITHIN MALIGNANT TUMORS AS MEASURED WITH ANTIMONY MICROELECTRODES

1981

Publisher Summary Recent experiments using glass microelectrodes have demonstrated that very low tissue pH-values are prevalent in C3H mouse mammary carcinomas. The acidification of the tumor tissue is the result of an elevated lactic acid production and its inadequate removal. As a consequence of heterogeneities in tumor blood flow and in substrate supply, tissue pH values are distributed heterogeneously within solid tumors. Although glass microelectrodes with tip diameters of about 1 μm and a sensitive length of 10–50 μm have been used, the spatial resolution can be improved utilizing glass coated antimony microelectrodes the sensitive areas of that are restricted to their very tips. This…

A response to ?Severe lactic acidosis following alcohol related generalised seizures?

2005

"Click" on PLGA-PEG and hyaluronic acid: gaining access to anti-leishmanial pentamidine bioconjugates

2018

Pentamidine (Pent), an antiparasitic drug used for the treatment of visceral leishmaniasis, has been modified with terminal azide groups and conjugated to two different polymer backbones (PLGA-PEG [PP] copolymer and hyaluronic acid [HA]) armed with alkyne end-groups. The conjugation has been performed by Copper Catalyzed Azido Alkyne Cycloaddition (CuAAC) using CuSO4/sodium ascorbate as metal source. The novel PP-Pent and HA-Pent bioconjugates are proposed, respectively, as non-targeted and targeted drug delivery systems against Leishmania infections. Moreover, Pent has been encapsulated into PP nanoparticles by the oil-in-water emulsion method, with the aim to compare the biological activi…

Monitoring biomarkers during preseason preparation period in professional soccer players

2011

Aim. The present study aimed at investigating the effect of a 3-week experimental intervention on biomarkers in professional soccer players during the preseason preparation-period. Methods. Eight participants (age 22.5±2.2 yrs) were enrolled in the study. During the physical preparation period players have attended a training program (51,9 hours) planned by coaches of “Equipe-Sicilia-2009”. Results. At rest, the lipid profile, the creatine kinase (CK), the lactic-acid dehydrogenase (LDH) and the expression of nuclear receptors peroxisome-proliferator-activated receptors (PPAR α/γ) were analyzed before starting and after 3 weeks of training sessions. The plasma level of CK in our samples sho…

Functional and Nutritious Beverages Produced by Lactic Acid Bacteria

2019

Abstract Currently, in the developed countries, there is a concern about leading a healthy lifestyle including eating “organic” and “functional” food. Moreover, in recent years, the percentage of the population with food allergies or intolerances has increased. Within this framework, lactic acid bacteria (LAB), which are able to ferment a variety of foodstuffs and also colonize the human digestive tract, can play a beneficial role. Many LAB strains have the generally recognized as safe (GRAS) status and are therefore being used in the food industry, especially to produce different types of fermented beverages, because they confer “functionality” to drinks due to the production of bioactive …

Lactic Acid Bacteria in Spanish Red Rose and White Musts and Wines under Cellar Conditions

1992

The dynamics of the lactic acid bacterial (LAB) population in different cellars, fermentation conditions and musts were analyzed. The number of LAB in fresh musts diminished quickly in the first few days, but an increase of these bacteria occurred during the later stages of the alcoholic fermentation. The species found in fresh musts were Lactobacillus plantarum, L. hilgardii, L. brevis, L. confusus, and Leuc. onostoc paramesenteroides. At the end of fermentation only L. hilgardii, Leuc. oenos and L. fructivorans were isolated. The API 50 CHL system was not useful to identify strains of Leuc. oenos species. All the isolated strains degraded malic acid in synthetic medium but only two strain…

Optimising Lactic Acid Cheese Packaging Systems

2016

On the basis of a previous research, it seems that foil-wrapped tray solutions are not particularly chosen by lactic acid cheese consumers. With relation to this study, almost half of the respondent population would have expressed the desire of different packages. Parchment packages and poly(ethylene-co-vinyl acetate)/polyvinylidene chloride/poly(ethylene-co-vinyl acetate) laminates would be removed by 25.0 and 12.5% of customers, respectively. Polyamide/polyethylene double and single packaging would be removed from the market only by 5.0% of respondents. Data have shown that cheese and packaging quality are dependent on lactic acid cheese surface microflora. The type of this microflora is …

Design of biopolymeric matrices entrapping bioprotective lactic acid bacteria to control Listeria monocytogenes growth: Comparison of alginate and al…

2014

In order to design biopolymeric matrices entrapping bioprotective lactic acid bacteria (LAB) to control undesirable microorganisms growth in foods, the performances of alginate and alginate-caseinate (an aqueous two-phase system) matrices entrapping Lactococcus lactis subsp. lactis LAB3 cells were compared. Since efficient matrices should preserve the culturability and the antimicrobial activity of entrapped LAB3 cells for prolonged periods, they were both monitored for 12 days storage at 30 °C. Maximal cell density (∼109 CFU mL−1) was reached after 24 h whatever the matrix type. Then, the LAB3 cells population decreased: 107 and 106 CFU mL−1 were enumerated after 12 days in alginate-casein…

Chitosan films for the microbiological preservation of refrigerated sole and hake fillets

2013

The effect of chitosan films for shelf-life extension of fresh fillets of hake (Merluccius merluccius) and sole (Solea solea) was evaluated over a 15-day storage at 4 ± 1 °C. Fish fillets wrapped in a chitosan matrix were individually packaged in air (AP) and under vacuum (VP). Microbiological analyses (total aerobic mesophilic bacteria, Pseudomonas, H2S-producing bacteria, lactic acid bacteria, Enterobacteriaceae and Listeria monocytogenes were carried out during the shelf-life. The microbial species were inhibited (p < 0.05) by the presence of chitosan films, especially under VP conditions. A significant (p < 0.05) increase of the lag phase and a reduction of the final microbial populatio…

Der Stoffwechsel verschiedener Carbons�uren durch Milchs�urebakterien

1984

The anaerobic metabolism of citrate, fumarate, gluconate, malate, 2-oxoglutarate and pyruvate by 137 strains of 23 species of lactic acid bacteria was investigated. The bacteria were from various sources (plant material, meat and dairy products, dough and wine) and belonged to the genera Lactobacillus, Leuconostoc, Pediococcus, and Streptococcus. The ability of metabolize the acids was determined by thin layer chromatography or by enzymatic analysis after growth of the strains in a glucose-containing medium. All strains metabolized pyruvate and only 12 mainly heterofermentative strains were malate negative. These strains were also unable to decompose citrate. This acid was fermented by 23 s…