Search results for "Activity"
showing 10 items of 7178 documents
Synthesis of novel 1,2,4-oxadiazole topsentin analogs with antitumor activity
2019
Synthesis of novel 1,2,4-oxadiazole topsentin analogs with antitumor activity
Synthesis and biological evaluation of some new 2-phenylpropiolamidobenzamides as potential antagonists of the HDM2-p53 protein-protein interactions
2009
Multiproperty complexes of 4d and 4f metal ions based on biomolecules: from fundamental research to potential applications
2023
El trabajo desarrollado en esta Tesis se enmarca en el campo de la Química de Coordinación y el Magnetismo Molecular, vectores base para el desarrollo de múltiples aplicaciones en Nanomedicina y Nanotecnología. El estudio de los compuestos de coordinación tiene una larga historia que se remonta a principios del siglo XIX, con notables contribuciones de químicos como Berzelius y Jørgensen. Esta rama de la química se centra en la comprensión de las propiedades de unión de los ligandos (moléculas o aniones donadores de electrones) a los iones metálicos. Las teorías de Alfred Werner sobre la coordinación de iones metálicos a principios del siglo XX marcaron un hito importante en este campo. El …
Mixotrophy in a Local Strain of Nannochloropsis granulata for Renewable High-Value Biomass Production on the West Coast of Sweden
2022
A local strain of Nannochloropsis granulata (Ng) has been reported as the most productive microalgal strain in terms of both biomass yield and lipid content when cultivated in photobioreactors that simulate the light and temperature conditions during the summer on the west coast of Sweden. To further increase the biomass and the biotechnological potential of this strain in these conditions, mixotrophic growth (i.e., the simultaneous use of photosynthesis and respiration) with glycerol as an external carbon source was investigated in this study and compared with phototrophic growth that made use of air enriched with 1–2% CO2. The addition of either glycerol or CO2-enriched air stimulated the…
Demonstration of a correlation between young leaves, apex and young bunches specific to a young grapevine cutting in the first period of its developm…
2001
<p style="text-align: justify;">The development of hardwood cutting of grapevine comprise 4 succesive phases. Phase I: first period of shoot extension. Phase II: characterized by a slow growth due to a very low activity of the terminal bud. Phase III: reactivation of the growth consecutive to a resumption of the apical activity. Phase IV: when the growth becomes maximal.</p><p style="text-align: justify;">The objective of this work has been to identify the cause of the slowdown of the activity of apical bud during the phase II.</p><p style="text-align: justify;">In a first experiment, we have compared the effects of three modes of defoliation applied from the b…
Political Action Beyond Resistance: Arendt and "Revolutionary Spirit" in Egypt
2016
The article examines what it calls the "politics-as-resistance" frame in contemporary political theory, originating in the works of Michel Foucault and Judith Butler. This way of organizing political experience is contrasted with Hannah Arendt's political thought, particularly her writings on revolutionary action. Arendt's often overlooked – and partly unpublished – passages on virtù and fortuna are further suggested as important additions to her thinking on action. I argue that Arendt's "world-centric" approach can illuminate certain aspects of political experience that remain dimmed in the more subject-oriented politics-as-resistance frame. Particular focus is paid to the austere notion o…
Design, Construction, and Characterization of a New Regioisomer and Diastereomer Material Based on the Spirooxindole Scaffold Incorporating a Sulphon…
2020
The 1,3-dipolar cycloaddition reaction is one of the most rapid, and efficient protocols to access, and construct highly divergent heterocycle chiral auxiliaries. Free catalyst synthesis of spirooxindole scaffold incorporating sulphone moiety via one pot&ndash
X-Ray structure, Hirshfeld analysis and DFT studies of two new hits of triazolyl-indole bearing alkylsulfanyl moieties
2021
Two new hits of triazolyl-indole containing two different alkylsulfanyl analogues named tert-butyl 2-((4-amino-5-(1H-indol-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetate 2, and ethyl 2-((4-amino-5-(1H-indol-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetate 3 were synthesized via reaction of 4-amino-5-(1H-indol-2-yl)-1,2,4-triazol-3(2H)-thione 1 with tert-butyl bromoacetate and ethyl chloroacetate in the presence of base (Et3N). The molecular structure of 2, and 3 was confirmed by single-crystal X-ray diffraction and 1H/13C- NMR spectroscopic techniques. In compound 2, the molecular packing depends on significant O...H (9.3%), N...H (12.4%) and S...H (3.1%) as well as relatively weak C...H (14.1%), S...C (…
Molecular Basis for Endocrine Disruption by Pesticides Targeting Aromatase and Estrogen Receptor
2020
The intensive use of pesticides has led to their increasing presence in water, soil, and agricultural products. Mounting evidence indicates that some pesticides may be endocrine disrupting chemicals (EDCs), being therefore harmful for the human health and the environment. In this study, three pesticides, glyphosate, thiacloprid, and imidacloprid, were tested for their ability to interfere with estrogen biosynthesis and/or signaling, to evaluate their potential action as EDCs. Among the tested compounds, only glyphosate inhibited aromatase activity (up to 30%) via a non-competitive inhibition or a mixed inhibition mechanism depending on the concentration applied. Then, the ability of the thr…
Tool use in mathematics: A framework
2015
International audience; In the course of research into the interpretation of tools in the didactics of mathematics I found both voids and conflicts. This paper presents the results of my research and a resultant statement on tool use in mathematics education. The statement incorporates constructs from several theoretical frameworks and I consider the consistency of my statement on tool use with regard to activity theory.