Search results for "Activity"

showing 10 items of 7178 documents

Synthesis and characterization of poly(phenylacetylenes) featuring activated ester side groups

2010

Four monomers based on 4-ethynylbenzoic acid have been synthesized, one of those featuring an activated ester. With the metathesis catalytic system WCI 6 /Ph 4 Sn, these acetylenic monomers could successfully be polymerized yielding conjugated polymers with molecular weights of around 10,000 to 15,000 g/mol and molecular weight distributions M w / M n < 2.1. Also the copolymerization of phenylacetylene or methyl 4-ethynylbenzoate with pentafluorophenyl 4-ethynyl-benzoate as reactive unit was conducted. Polymer analogous reactions of the reactive polymers and copolymers with amines have been investigated and it was found that poly(pentafluorophenyl 4-ethynylbenzoate) featured a significant r…

chemistry.chemical_classificationPolymers and PlasticsOrganic ChemistryPolymerConjugated systemMetathesischemistry.chemical_compoundMonomerchemistryPhenylacetylenePolymerizationPolymer chemistryMaterials ChemistryCopolymerReactivity (chemistry)Journal of Polymer Science Part A: Polymer Chemistry
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Synthesis and polymerization of active ester monomers based on 4-vinylbenzoic acid

2007

Abstract Nine active ester monomers based on 4-vinylbenzoic acid have been synthesized. Under free radical polymerization conditions these monomers could successfully be polymerized yielding reactive polymers with molecular weights of around M n  = 20.000–50.000 g/mol and molecular weight distributions M w / M n of around or below 2 in good yields. Polymer analogous reactions with amines have been investigated by time-resolved FT-IR spectroscopy and it was found that especially poly(pentafluorophenyl 4-vinylbenzoate) featured a significant reactivity, such that polymer analogous reactions proceeded quantitatively with amines within less than 5 min at 0 °C.

chemistry.chemical_classificationPolymers and PlasticsOrganic ChemistryRadical polymerizationGeneral Physics and AstronomyChemical modificationPolymerRing-opening polymerizationchemistry.chemical_compoundMonomerchemistryPolymerizationPolymer chemistryMaterials ChemistryReactivity (chemistry)Functional polymersEuropean Polymer Journal
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The anionic copolymerization of 5-(N,N-diisopropylamino)isoprene with styrene

1995

The anionic copolymerization of 5-(N,N-diisopropylamino)isoprene (N,N-diisopropyl-2-vinylallylamine) and styrene initiated with alkyllithium compounds is studied. Copolymers obtained from different compositions are characterized by size-exclusion chromatography (SEC), differential scanning calorimetry and by 1 H NMR and 13 C NMR spectroscopy. Under these conditions the dialkylaminoisoprene, similar to butadiene and isoprene, is more reactive than styrene and is incorporated faster into the polymer backbone. The incomplete conversion of the monomers has been attributed to the formation of intra-or intermolecular complexes between the Li + counterion at the chain end and amino groups. Because…

chemistry.chemical_classificationPolymers and PlasticsTertiary amineOrganic ChemistryCarbon-13 NMRCondensed Matter PhysicsStyrenechemistry.chemical_compoundMonomerchemistryPolymer chemistryMaterials ChemistryCopolymerReactivity (chemistry)Physical and Theoretical ChemistryCounterionIsopreneMacromolecular Chemistry and Physics
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Biopartitioning micellar chromatography: An alternative high-throughput method for assessing the ecotoxicity of anilines and phenols

2007

An investigation of the use of the chromatographic retention (log k) as an in vitro approach for modelling the toxicity to Fathead Minnows of anilines and phenols is developed. A data set of 65 compounds with available experimental toxicity data was used. Log k data at three pH values were used for the compounds classification and two groups or 'MODEs' were identified. For one 'MODE' a quantitative retention-activity relationship (QRAR) model was calculated. Finally, it was used to estimate the toxicity to Fathead minnows of anilines and phenols for which experimental data are not available. These estimations were compared to those obtained from another toxicity (to Tetrahymena pyriformis) …

chemistry.chemical_classificationQuantitative structure–activity relationshipAniline CompoundsChromatographyToxicity dataTetrahymena pyriformisClinical BiochemistryCyprinidaeQuantitative Structure-Activity RelationshipAromatic amineExperimental dataCell BiologyGeneral MedicineBiochemistryAnalytical Chemistrychemistry.chemical_compoundPhenolschemistryTetrahymena pyriformisToxicityAnimalsSpectrophotometry UltravioletPhenolsEcotoxicityChromatography Micellar Electrokinetic CapillaryJournal of Chromatography B
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Photooxidations of Alkenes in Fluorinated Constrained Media:  Fluoro-organically Modified NaY as Improved Reactors for Singlet Oxygen “Ene” Reactions

2007

Creating a stationary fluorinated environment inside the zeolite cavity can increase the reactivity observed for intrazeolite photooxidation of alkenes. Exchanging the zeolite with fluorinated organic cations is a much more effective strategy than simply using a fluorinated solvent for slurry irradiations. Use of cations containing C-F bonds is also more efficient than use of deuterated cations for creation of a singlet oxygen friendly environment where the quenching processes are slowed down. Doping the zeolite with fluoro-organic cation 4 resulted in an increase in the singlet oxygen lifetime to 12 micros.

chemistry.chemical_classificationQuenching (fluorescence)ZEOLITESChemistryAlkeneSinglet oxygenOrganic ChemistryInorganic chemistryINTRAZEOLITE PHOTOOXIDATIONSLIFETIMEOXIDATIONPhotochemistrySolventchemistry.chemical_compoundCHEMISTRYReactivity (chemistry)Singlet stateDEACTIVATIONOLEFINSZeoliteEne reactionThe Journal of Organic Chemistry
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Substituent effect on oxidative cyclization of aldehyde thiosemicarbazones with ferric chloride

1991

The reactivity of aldehyde thiosemicarbazones 1 with ferric chloride solutions was examined. When compounds 1 are not substituted on the N-2 nitrogen atom formation of 1,3,4-thiadiazole 3 heterocyclic ring was observed. In contrast 1,2,4-triazoline 4 and/or 1,3,4-thiadiazoline 5 heterocyclic rings were afforded when N-2 nitrogen atom carried a methyl or a phenyl group. The reaction mechanism is also discussed.

chemistry.chemical_classificationReaction mechanismChemistryOrganic ChemistrySubstituentRing (chemistry)ChlorideMedicinal chemistryAldehydechemistry.chemical_compoundmedicinePhenyl groupFerricReactivity (chemistry)medicine.drugJournal of Heterocyclic Chemistry
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Enhancing reactivity of carbonyl compounds via hydrogen-bond formation. A DFT study of the hetero-Diels-Alder reaction between butadiene derivative a…

2003

To examine how hydrogen-bond (HB) formation involving chloroform solvent molecules influences the chemical reactivity of ketones, the hetero-Diels-Alder reaction of N,N-dimethyl-1-amino-3-methoxy-1,3-butadiene and acetone has been studied by using density functional theory (DFT) at the B3LYP/6-31G level. The effects of the chloroform on the activation energies have been modeled by means of discrete-continuum models. In the gas phase, the formation of specific HB between acetone and one and two chloroform molecules decreases the activation barriers from 19.3 to 13.6 and 8.5 kcal/mol, respectively. Inclusion of solvent effects by means of combined discrete and polarizable continuum models yie…

chemistry.chemical_classificationReaction mechanismChloroformKetoneHydrogen bondOrganic ChemistrySolvationMedicinal chemistrySolventchemistry.chemical_compoundchemistryOrganic chemistryReactivity (chemistry)Solvent effectsThe Journal of organic chemistry
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An ELF analysis of the C–C bond formation step in the N-heterocyclic carbene-catalyzed hydroacylation of unactivated C–C double bonds

2012

The changes in electron-density along the C–C bond-formation step in the N-heterocyclic carbene-catalyzed hydroacylation of unactivated double bonds has been studied by an electron localization function (ELF) analysis at the B3LYP/6-31G** level in order to characterize the reaction mechanism. Analysis of DFT reactivity indices and the natural bond orbital and ELF analysis at the most relevant points of the intrinsic reaction coordinate indicate that the reaction path takes place through a two-stage one-step mechanism with non-polar character. In the first stage a hydrogen atom is transferred from the hydroxyl group of Breslow intermediate 12 to the terminal olefinic carbon atom, to yield a …

chemistry.chemical_classificationReaction mechanismDouble bondStereochemistryGeneral Chemical EngineeringStetter reactionHydroacylationGeneral Chemistrychemistry.chemical_compoundchemistryIntramolecular forceReactivity (chemistry)CarbeneNatural bond orbitalRSC Advances
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On the Dichotomic Behavior of the Z-2,4-Dinitrophenylhydrazone of 5-Amino-3-benzoyl-1,2,4-oxadiazole with Acids in Toluene and in Dioxane/Water:  Rea…

2004

The mononuclear rearrangement (MRH) of the Z-2,4-dinitrophenylhydrazone (4a) and of the Z-phenylhydrazone (4b) of 5-amino-3-benzoyl-1,2,4-oxadiazole into the relevant triazoles 5a and 5b in toluene has been quantitatively investigated in the presence of trichloroacetic acid (TCA) and of piperidine at 313.1 K. While the behavior in the presence of piperidine recalls the one previously evidenced for some Z-hydrazones of 3-benzoyl-5-phenyl-1,2,4-oxadiazole, the study of the reactivity in the presence of TCA has most interestingly evidenced a general-acid-catalyzed rearrangement for “both” 4a and 4b. Thus, 4a offers the first example of a solvent-dependent dichotomic behavior in MRH processes o…

chemistry.chemical_classificationReaction mechanismOrganic Chemistryacid catalysiOxadiazoleHydrazoneMedicinal chemistryToluenechemistry.chemical_compoundHydrolysisAcid catalysischemistryOrganic chemistrymononuclear rearrangement of heterocycleReactivity (chemistry)Piperidinebase catalysisThe Journal of Organic Chemistry
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ChemInform Abstract: Substituent Effect on Oxidative Cyclization of Aldehyde Thiosemicarbazones with Ferric Chloride.

2010

The reactivity of aldehyde thiosemicarbazones 1 with ferric chloride solutions was examined. When compounds 1 are not substituted on the N-2 nitrogen atom formation of 1,3,4-thiadiazole 3 heterocyclic ring was observed. In contrast 1,2,4-triazoline 4 and/or 1,3,4-thiadiazoline 5 heterocyclic rings were afforded when N-2 nitrogen atom carried a methyl or a phenyl group. The reaction mechanism is also discussed.

chemistry.chemical_classificationReaction mechanismSubstituentGeneral MedicineRing (chemistry)AldehydeMedicinal chemistryChloridechemistry.chemical_compoundchemistrymedicineFerricOrganic chemistryPhenyl groupReactivity (chemistry)medicine.drugChemInform
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