Search results for "Actor"

Obesity and diabetes-Not only a simple link between two epidemics

2018

Summary Diabetes (DM) as well as obesity, due to their increasing incidence, were recognized as epidemic by the World Health Organization. Obesity is involved not only in the aetiopathogenesis of the most common worldwide type of DM—type 2 diabetes—but also in the development of its complications. There is also increasing scientific evidence regarding the role of obesity and overweight in type 1 diabetes. Weight gain may be considered as a complication of insulin treatment but also reveals significant pathophysiological impact on various stages of the disease. Another very important aspect related to DM as well as obesity is the microbiome, which is highly variable. The function of the gut …

Organisational climate and employee health outcomes: a systematic review

2019

Organisational climate, particularly safety climate, has been documented as a crucial element in promoting occupational health and safety. However, most previous studies have focused more on safety issues (e.g., injuries and accidents) rather than health outcomes (e.g., illnesses, stress, etc). A comprehensive review is also lacking in relation to understanding the organisational climate–health relationship between different levels of analysis, different data sources and different analytical procedures. We conducted a systematic review to investigate previous scholarly contributions to organisational climate and health. The reviewed articles were obtained from three databases: ISI Web of Kn…

Odorants' metabolism in Human: a critical role in odor perception revealed

2018

Système olfactif et neurobiologie

2006

Les connaissances neurobiologiques sur l’odorat progressent désormais rapidement depuis la découverte des récepteurs des odorants, remarquables par leur grand nombre et leur diversité. Des réponses sont maintenant apportées aux questions posées par les propriétés originales de la perception olfactive dont beaucoup sont déterminées dès le niveau de l’organe olfactif, et sont fortement déterminées par la génétique. Les connaissances génétiques sur les récepteurs dévoilent une considérable réduction du nombre de gènes olfactifs fonctionnels dans l’espèce humaine et alimentent une réflexion sur l’évolution de l’odorat. Autre avancée riche de promesses : l’application à l’olfaction des méthodes …

Silencing of C3G increases cardiomyocyte survival inhibition and apoptosis via regulation of p-ERK1/2 and Bax

2019

Experimental studies have shown that overexpression of Rap guanine nucleotide exchange factor 1 (C3G) plays pro‐survival and anti‐apoptotic roles through molecule phosphorylated extracellular signal‐regulated kinase1/2 (p‐ERK1/2) in cardiomyocytes. However, it is still unclear if silencing of C3G may increase cell survival inhibition and apoptosis in cardiomyocytes, and whether C3G silence induced injuries are reduced by the overexpression of C3G through regulation of p‐ERK1/2 and pro‐apoptotic molecule Bax. In this study, the rat‐derived H9C2 cardiomyocytes were infected with C3G small hairpin RNA interference recombinant lentiviruses, which silenced the endogenous C3G expression in the ca…

WRKY gene family drives dormancy release in onion bulbs

2022

Onion (Allium cepa L.) is an important bulb crop grown worldwide. Dormancy in bulbous plants is an important physiological state mainly regulated by a complex gene network that determines a stop of vegetative growth during unfavorable seasons. Limited knowledge on the molecular mechanisms that regulate dormancy in onion were available until now. Here, a comparison between uninfected and onion yellow dwarf virus (OYDV)-infected onion bulbs highlighted an altered dormancy in the virus-infected plants, causing several symptoms, such as leaf striping, growth reduction, early bulb sprouting and rooting, as well as a lower abscisic acid (ABA) level at the start of dormancy. Furthermore, by compar…

Vapaalaskuvälineiden ja -brändien eWOM-viestinnän motivaatiotekijät

2015

Viestintä erilaisissa online-kanavissa on nykypäivänä yleinen tapa olla vuoro-vaikutuksessa tuttujen, mutta myös tuntemattomien henkilöiden kanssa. Verkkovälitteinen suusanallinen viestintä, eWOM-viestintä on noussut digitaalisessa maailmassa tärkeäksi markkinointivälineeksi yrityksille. eWOM-viestintä ja online-suosittelu on osa jokapäiväistä vuorovaikutusta arvostelusivustoilla, so-siaalisissa verkkoyhteisöissä, blogeissa, sisällönjakosivustoilla sekä muissa sosi-aalisen median kanavissa. eWOM-viestintä on tärkeää kaikille organisaatioille, se viestittää yritykselle kuluttajien asenteista ja mielipiteistä tuotteita tai palve-luja kohtaan. Kuluttajien asenteet ja mielipiteet ovat tärkeitä …

The role of health literacy in the association between academic performance and substance use.

2022

Abstract Background To address social inequalities in adolescent substance use and consequent disparities in health, it is important to identify the mechanisms of the association between substance use and academic performance. We study the role of health literacy (HL) in the association between academic performance and weekly smoking, monthly alcohol use and cannabis ever-use among adolescents in Europe. Methods SILNE-R school survey data, which was collected in 2016–17 with paper-and-pencil-method from Hanover (GE), Amersfoort (NL) and Tampere (FI), were used (N = 5088, age 13–19). Health Literacy for School-aged Children instrument was used to assess students’ HL. Logistic regression anal…

Mediating effects of motor performance, cardiorespiratory fitness, physical activity, and sedentary behaviour on the associations of adiposity and ot…

2018

We investigated the associations of cardiometabolic risk factors with academic achievement and whether motor performance, cardiorespiratory fitness, physical activity, or sedentary behaviour mediated these associations. Altogether 175 children 6-8 years-of-age participated in the study. We assessed body fat percentage (BF%), waist circumference, insulin, glucose, triglycerides, HDL cholesterol, and systolic and diastolic blood pressure, leptin, alanine aminotransferase, and gamma-glutamyltransferase (GGT). Reading fluency, reading comprehension, and arithmetic skills were assessed using standardized tests. Speed/agility, balance, and manual dexterity test results were used to calculate moto…

Energy Drink Consumption Among Finnish Adolescents: Prevalence, Associated Background Factors, Individual Resources, and Family Factors.

2020

Objectives: Energy drink consumption among adolescents has become a notable global phenomenon, and has been associated with numerous negative health outcomes. In order to understand the popularity of energy drinks among adolescents, and to target interventions, it is important to identify the determinants underpinning consumption. Methods: The nationally representative data (cross-sectional) were drawn from the Health Behaviour in School-aged Children (HBSC) surveys, conducted in 2014 and 2018, each comprising 13- and 15-year-old Finnish adolescents (n = 7405). Results: Weekly energy drink consumption increased among Finnish adolescents between 2014 (18.2%) and 2018 (24.4%), especially amon…