Search results for "Actor"

showing 10 items of 19159 documents

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

2013

Journal article Breast cancer is the most common cancer among women. Common variants at 27 loci have been identified as associated with susceptibility to breast cancer, and these account for ~9% of the familial risk of the disease. We report here a meta-analysis of 9 genome-wide association studies, including 10,052 breast cancer cases and 12,575 controls of European ancestry, from which we selected 29,807 SNPs for further genotyping. These SNPs were genotyped in 45,290 cases and 41,880 controls of European ancestry from 41 studies in the Breast Cancer Association Consortium (BCAC). The SNPs were genotyped as part of a collaborative genotyping experiment involving four consortia (Collaborat…

signaling pathwayGenotypingGenotypeSingle-nucleotide polymorphismGenome-wide association studyBreast NeoplasmsconsortiumBiologyBreast Neoplasms; Case-Control Studies; Cooperative Behavior; Female; Gene-Environment Interaction; Genetic Loci; Genome-Wide Association Study; Genotype; Humans; Meta-Analysis as Topic; Polymorphism Single Nucleotide; Risk Factors; Genetic Predisposition to Disease; GeneticsPolymorphism Single NucleotideArticle03 medical and health sciences0302 clinical medicineBreast cancerSDG 3 - Good Health and Well-beingMeta-Analysis as TopicRisk FactorsGenotypecommon variantsexpressionGeneticsmedicineHumansGenetic Predisposition to DiseasePolymorphismCooperative BehaviorgeneGenotypinghormone-related protein030304 developmental biologyGenetic associationGenetics0303 health sciencesBreast cancer susceptibilityCancerSingle Nucleotidemedicine.diseaseconfer susceptibilitysusceptibility loci3. Good health14q24.1 rad51l1TOX3Genetic Loci030220 oncology & carcinogenesisCase-Control Studiesgenome-wide associationFemaleGene-Environment InteractionGenome-Wide Association Study
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La politique éolienne et ses effets sur le développement local. Une analyse basée sur le système des acteurs (Loja, Equateur)

2020

La política energética ecuatoriana pretende que las centrales eléctricas contribuyan al desarrollo local en las áreas en las que se implantan. A partir del caso de estudio del Parque Eólico Villonaco (PEV), la pregunta de investigación que se plantea es si el Plan de Desarrollo Territorial Comunitario (PDTC) que se está implementando en la zona de influencia del Parque, está teniendo efectos socio-territoriales positivos. Se utiliza una metodología cualitativa, a partir de entrevistas semiestructuradas a actores clave. Los resultados obtenidos indican que la central eólica ha empezado a tener efectos positivos en el ámbito de los equipamientos educativos, la infraestructura vial, o en el al…

sistema de actoresrenewable energiesstakeholder analysis020209 energydesarrollo local05 social sciencesGeography Planning and Developmentdéveloppement localsystème des acteurs02 engineering and technologyEconomialocal development0506 political scienceenergías renovablesUrban Studies050602 political science & public administration0202 electrical engineering electronic engineering information engineeringEnergies renovablesénergies renouvelables
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La viabilidad de las pensiones en una economía global en crisis

2015

La tesis pretende estudiar la situación de los sistemas de pensiones desde un punto de vista global y comparativo. Para ello hace un estudio histórico, social, económico y sobre todo jurídico de los principales países europeos y de latinoamericanos. Se analiza asimismo el papel de determinadas entidades en materia de pensiones como el FMI, el Banco Mundial o la Troika, el funcionamiento del mercado laboral en distintos países y el papel de las pensiones complementarias en sus distintos ámbitos.

sistema de capitalizaciónpensiones en latinoaméricafactor de sostenibilidad:CIENCIAS JURÍDICAS Y DERECHO [UNESCO]UNESCO::CIENCIAS JURÍDICAS Y DERECHO:SOCIOLOGÍA [UNESCO]tercera víasistema de repartopensionesestado de bienestarpensiones en europaUNESCO::SOCIOLOGÍArevalorización de las pensionessistema de cuentas nocionales
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MVU ekonomiskās izaugsmes noteicēji Vācijā un Latvijā, fokuss uz ražošanas MVU

2021

Šis darbs ir veltīts mazo un vidējo uzņēmumu (MVU) un to izaugsmes faktoru analīzei. Tajā izklāstīti dažādi faktori, kas ietekmē MVU attīstību, kā arī izaicinājumi un perspektīvas, ar ko tie sastopas mūsdienu globalizētajā un digitalizētajā ekonomikā. Darbā plaši iztirzāta MVU būtiskā loma ekonomikas un sociālās dimensijas iekļaujošā izaugsmē. Šajā darbā arī iekļautas dažādas stratēģijas un valsts programmas, kam ir labvēlīgs iespaids uz uzņēmumu produktivitāti un attīstību. Padziļinātas izpratnes radīšanai kā piemērs ir izvēlēts mazo un vidējo uzņēmumu sektors Latvijā un Vācijā, identificējot abu sektoru trūkumus un priekšrocības.

size and agegrowth factorsEkonomikabusiness environmentchallengesfinancing
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Excessive Daytime Sleepiness in Obstructive Sleep Apnea Patients Treated With Continuous Positive Airway Pressure: Data From the European Sleep Apnea…

2021

Excessive daytime sleepiness (EDS) is a symptom of obstructive sleep apnea (OSA) that resolves under treatment with continuous positive airway pressure (CPAP). In some patients, sleepiness persists despite CPAP treatment. We retrospectively analyzed data on subjective residual EDS, assessed as an Epworth Sleepiness Scale score (ESS) >10, in patients from the European Sleep Apnea Database (n = 4,853, mean age +/- SD 54.8 +/- 11.8 years, 26.1% females), at baseline and at the first visit (median follow-up: 5 months, interquartile range 3-13). An ESS > 10 occurred in 56% of patients at baseline and in 28.2% of patients at follow-up. Residual EDS was analyzed in 2,190 patients (age: 55.1 +/- 12…

sleep latencyResidual Sleepinessmedicine.medical_treatment[SDV]Life Sciences [q-bio]Excessive daytime sleepinessSettore MED/10 - Malattie Dell'Apparato Respiratoriocomputer.software_genreCpap adherence03 medical and health sciences0302 clinical medicineInterquartile rangeCpap Usemedicinefollow-upContinuous positive airway pressureObesityRC346-429ComputingMilieux_MISCELLANEOUSresidual sleepnessOriginal ResearchWake-Active NeuronsDatabasebusiness.industryresidual sleepineEpworth Sleepiness ScaleSleep apneaEpworth sleepness ScaleEpworth Sleepiness Scalemedicine.diseaseCPAP adherenceImportant Differencenervous system diseasesrespiratory tract diseasesScaleObstructive sleep apneaLifestyle factors030228 respiratory systemNeurologysleep durationHuman medicineNeurology. Diseases of the nervous systemNeurology (clinical)medicine.symptombusinesscomputer030217 neurology & neurosurgery
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Implementation of IT applications in small and middle size enterprises : controlling the critical success factors

2002

small and middle size enterprisestietotekniikkasuccess factorsIT implementation processhyödyntäminenpienet ja keskisuuret yrityksetcontrol methods
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Atherosclerosis Development and Progression: The Role of Atherogenic Small, Dense LDL.

2022

Atherosclerosis is responsible for large cardiovascular mortality in many countries globally. It has been shown over the last decades that the reduction of atherosclerotic progression is a critical factor for preventing future cardiovascular events. Low-density lipoproteins (LDL) have been successfully targeted, and their reduction is one of the key preventing measures in patients with atherosclerotic disease. LDL particles are pivotal for the formation and progression of atherosclerotic plaques; yet, they are quite heterogeneous, and smaller, denser LDL species are the most atherogenic. These particles have greater arterial entry and retention, higher susceptibility to oxidation, as well a…

small dense LDL.lipoproteinGeneral MedicineCVDAtherosclerosisresidual risklipoproteinsLipoproteins LDLatherosclerosipreventionRisk FactorsHumansCVD atherosclerosis lipoproteins prevention residual risk small dense LDLlipids (amino acids peptides and proteins)atherosclerosisInsulin Resistancesmall dense LDLDyslipidemiasMedicina (Kaunas, Lithuania)
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Antennal lobe representations are optimized when olfactory stimuli are periodically structured to simulate natural wing beat effects

2014

Animals use behaviors to actively sample the environment across a broad spectrum of sensory domains. These behaviors discretize the sensory experience into unique spatiotemporal moments, minimize sensory adaptation, and enhance perception. In olfaction, behaviors such as sniffing, antennal flicking, and wing beating all act to periodically expose olfactory epithelium. In mammals, it is thought that sniffing enhances neural representations; however, the effects of insect wing beating on representations remain unknown. To determine how well the antennal lobe produces odor-dependent representations when wing beating effects are simulated, we used extracellular methods to record neural units an…

sniffingPopulation Dynamicsactive sensingSensory systemodor representationLocal field potentialOlfactionBiologylcsh:RC321-57103 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicinetemporal codingSniffingmedicineOriginal Research Articlelcsh:Neurosciences. Biological psychiatry. Neuropsychiatry030304 developmental biologyDiscrimination (Psychology)Stimulus discrimination0303 health sciencesSensory AdaptationCommunicationbusiness.industrysynchronynetwork dynamicsmedicine.anatomical_structureOdoroscillationsAntennal lobebusinessNeuroscienceOlfactory epithelium030217 neurology & neurosurgeryNeuroscienceolfactionFrontiers in Cellular Neuroscience
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Bezpieczeństwo państwa — czynniki miękkie

2019

This article is divided into three parts, in the fi rst part it is explained what social capital is, and its role in national security is depicted. In the second part, the problem of the importance of social rules in the construction of social capital is discussed. The third part of the article is the culmination of the analysis and shows the role of soft factors in the process of building national security. The quality of social capital depends on how the society works. It is strongly related to other pillars of state security, including the armed forces. The most important message from the content of this article is the statement: a strong society means a safe state.

social capitalsoft factorsnational securityStudia nad Autorytaryzmem i Totalitaryzmem
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Social aspects of the power of the state on the example of the visegrad group countries

2018

The article presents the social dimension of the power of the state. A comparative analysis of the dynamics of social progress of the Visegrad Group countries and a statistical analysis of social power-building factors have been carried out. The results presented in the article are the next stage of the author’s work on developing an analytical sub-model of the power of the state in the social area

social developmentpower of the statesocial power-building factors
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