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showing 10 items of 19159 documents
Ultraviolet A1 radiation induces nitric oxide synthase-2 expression in human skin endothelial cells in the absence of proinflammatory cytokines.
2001
Skin exposure to ultraviolet radiation from sunlight causes erythema and edema formation as well as inflammatory responses. As some of these ultraviolet-induced effects are potentially mediated by nitric oxide synthases, we examined the role of cytokines and ultraviolet A 1 radiation (340–400 nm) on the expression of the nitric oxide synthase-2 in endothelia of normal human skin biopsies during short-term organ culture as well as expression and activity of the nitric oxide synthase-2 in in vitro cell cultures of human dermal endothelial cells. Both, cytokine challenge (interleukin-1β + tumor necrosis factor-α + interferon-γ) but also ultraviolet A 1 exposure (50 J per cm 2 ) in the absence …
Influence of Viscosity on Mass Transfer Performance of Unbaffled Stirred Vessels
2013
Unbaffled stirred tanks are seldom employed in the process industry as they are considered poorer mixers than baffled vessels. However they may be expected to provide significant advantages in a wide range of applications (e.g. crystallization, food and pharmaceutical processes, etc) where the presence of baffles is often undesirable. Moreover, in plants or animal cell cultivation bioreactors, where cell damage is often caused by bursting bubbles at the air –medium interface (Barret et al., 2010), they can provide sufficient mass transfer through the free surface vortex, so bubble formation and subsequent bursting inside the reactor can be conveniently avoided (Scargiali et al., 2012). In t…
Zīdaiņu mirstības atšķirības Baltijas reģionā - Latvijā, Igaunijā, Lietuvā saistībā ar makroekonomiskajiem faktoriem no 2010. līdz 2016. gadam
2020
Tēmas pamatojums: Zīdaiņu un bērnu līdz 5 mirstība ir viens no galvenajiem valstu un bērnu labklājības rādītājiem, kas joprojām ir augsti pat vairākās attīstītās valstīs. Šī iemesla dēļ ir svarīgi monitorēt veicinošos faktorus, kas rada bērnu mirstības riskus agrīnā vecumā reģionālā perspektīvā, lai varētu tos mazināt un novērst. i,. Pētījumu sērija, ko veica LU MF Pediatrijas katedra Valsts pētījumu programmas ietvaros (1996 – 2010), identificēja cēloņsakarības starp bērnu mirstību un atsevišķiem socio- un makro-ekonomiskiem faktoriem Baltijas valstīs un atklāja atšķirības to savstarpējā mijiedarbā Latvijā, salīdzinājumā ar Lietuvu un Igauniju. MērķisMērķis bija konstatēt vai Baltijas reģi…
Relationships Between Health Promoting Activities, Life Satisfaction, and Depressive Symptoms in Unemployed Individuals
2021
Background: Previous research has documented that unemployed individuals who engage in recreational activities, either alone or with others, experience higher levels of mental health and psychological well-being relative to those who do not engage in recreational activities. Aims: In this study, we examined whether engagement in health promoting activities, alone or with other family members, is associated with reduced levels of depression and enhanced levels of life satisfaction in unemployed individuals. Method: We employed a cross-sectional design in which we measured life satisfaction, depressive symptoms, consumption of healthy meals and engagement in physical activities in 203 unemplo…
Role of post mortem computed tomography in diagnosis of upper cervical fractures in child due to road accident: A case report and literature review
2019
The upper cervical spine has unique anatomical features that distinguish it from the remainder of the cervical spine. Its motion segments make up a large amount of total cervical spine motion and, as a result,predispose it to a unique set of injuries. Cervical spine trauma is a common problem with a wide range of severity from minor ligamentous injury to section of the spinal cord. The use of post mortem CT (PMCT), and the subsequent multi-planar and volume rendering reconstruction techniques can provide non-invasive, objective operator-independent imaging data set that may be further reviewed by other specialists. and can substantially add to forensic examinations of the skeleton, especial…
Rigenerazione dell’area dell’ex fabbrica tessile Gulì a Palermo
2018
L’attività industriale palermitana, pur avendo vissuto un periodo fiorente piuttosto breve, ha lasciato tracce ben riconoscibili e identificabili all’interno del tessuto urbano, con manufatti architettonici di notevole importanza per qualità di progetto e dimensioni. L’ex fabbrica tessile Gulì è un complesso interessante sia dal punto di vista architettonico sia per la sua localizzazione urbanistica, molto prossima a poli di rilevante interesse culturale. Lo studio, condotto presso il Dipartimento di Architettura dell’Ateneo di Palermo, propone un intervento di rigenerazione che coinvolge non solo i manufatti edilizi presenti ma l’intera area e la sua trasformazione in un nuovo centro di qu…
Watch your step! Is foot landing technique during cutting manoeuvres associated with acute lower extremity injuries? : a 12-month prospective cohort …
2019
Useita pallopelejä luonnehtivat erilaiset nopeat suunnanmuutokset sekä äkilliset kiihdytykset, mitkä altistavat etenkin nuoria urheilijoita akuuteille alaraajavammoille. Aiempien tutkimusten valossa on esitetty, että jalkaterän laskeutumistekniikka saattaisi olla yhteydessä vammariskiin sekä erityyppisiin juoksuvammoihin. Hyvin vähän tiedetään kuitenkin jalkaterän laskeutumistekniikan yhteyksistä alaraajojen kinematiikkaan erityisesti nopeiden suunnanmuutosten aikana. Tämän tutkimuksen tarkoituksena oli selvittää, onko nopeiden suunnanmuutosten yhteydessä esiintyvällä jalkaterän laskeutumistekniikalla yhteys nuorten palloilijoiden akuutteihin, ilman suoraa kontaktia, tapahtuneisiin nilkan- …
Incidence and Risk Factors of Upper Extremity Injuries in Young Adult Men : A Nationwide Registry-Based Study of 128,714 Conscripts
2020
Introduction Injuries are the major cause of morbidity and loss of active training days in military populations. Previous investigations have mainly focused on lower extremities. This study evaluated the incidence, diagnosis, and risk factors of upper extremity injuries requiring hospitalization in a large cohort of Finnish conscripts during a 5-year period. Materials and Methods A total of 128,714 male military conscripts, who served 6–12 months in compulsory military service, were studied. Injury hospitalization data were obtained from the National Hospital Discharge Register. The main outcome variables were hospitalization due to any injuries to the upper extremity and hospitalization du…
Inter‐individual variation of the urinary steroid profiles in Swedish and Norwegian athletes
2020
The steroidal module of the Athlete Biological Passport (ABP) aims to detect doping with endogenous steroids, e.g. testosterone (T), by longitudinally monitoring several biomarkers. These biomarkers are ratios combined of urinary concentrations of testosterone and metabolically related steroids. However, it is evident after five years of monitoring steroid passports, that there are large variations in the steroid ratios complicating its interpretation. In this study, we used over 11 000 urinary steroid profiles from Swedish and Norwegian athletes to determine both the inter‐ and intra‐individual variations of all steroids and ratios in the steroidal passport. Furthermore, we investigated if…
Regulation of type 1 fimbriae synthesis and biofilm formation by the transcriptional regulator LrhA of Escherichia coli
2005
Type 1 fimbriae ofEscherichia colifacilitate attachment to the host mucosa and promote biofilm formation on abiotic surfaces. The transcriptional regulator LrhA, which is known as a repressor of flagellar, motility and chemotaxis genes, regulates biofilm formation and expression of type 1 fimbriae. Whole-genome expression profiling revealed that inactivation oflrhAresults in an increased expression of structural components of type 1 fimbriae.In vitro, LrhA bound to the promoter regions of the twofimrecombinases (FimB and FimE) that catalyse the inversion of thefimApromoter, and to the invertible element itself. TranslationallacZfusions with these genes and quantification offimEtranscript le…