Search results for "Adapta"
showing 10 items of 1961 documents
Genetic determinisms, evolution and detection of non-target-site based resistance to herbicides inhibiting acetolactate-synthase in rye-grass (Lolium…
2016
The aim of this study is to unravel the genetic determinism of non-target-site resistance (NTSR) to herbicides inhibiting acetolactate-synthase (ALS) in the major weed rye-grass (Lolium sp.), and to estimate the feasibility of NTSR diagnosis based on genetic data. On the one hand, this work contributes to the understanding of the processes driving the evolution of NTSR to herbicides, and on the other hand it lays the foundations for the development of a diagnosis tool to identify NTSR to ALS inhibiting herbicides. - Using a quantitative transcriptome sequencing approach, we showed that NTSR evolve by recurrent selection of higher and higher constitutive expression levels of genes involved i…
L’architecture des plantes de pois : un levier pour améliorer leur tolérance aux stress abiotiques
2017
Engineering school
Climate change: where are we right now?
2019
15ème Rencontres Bourgogne-Franche-Comté Nature : Changement climatique, humanité et biodiversité; International audience; Greenhouse gases (GHGs), naturally part of the atmosphere, have protected us from severe glaciations in thepast. Today, human activities increase GHG concentrations and cause rapid and unprecedented Earth warming.Climate change is not resumed only to warming, water cycle is also changed. All the researches confi rm: the climateis changing fast, too fast for ecosystems and societies to adapt. Despite the alerts of the international scientifi ccommunity, States gathered into Conferences of the Parties (COP) ratify agreements but do not comply with all theircommitments. Pu…
The Crosstalk of Adipose-Derived Stem Cells (ADSC), Oxidative Stress, and Inflammation in Protective and Adaptive Responses
2020
International audience; The potential use of stem cell-based therapies for the repair and regeneration of various tissues and organs is a major goal in repair medicine. Stem cells are classified by their potential to differentiate into functional cells. Compared with other sources, adipose-derived stem cells (ADSCs) have the advantage of being abundant and easy to obtain. ADSCs are considered to be tools for replacing, repairing, and regenerating dead or damaged cells. The capacity of ADSCs to maintain their properties depends on the balance of complex signals in their microenvironment. Their properties and the associated outcomes are in part regulated by reactive oxygen species, which medi…
Persistent establishment of a tropical disease in Europe: the preadaptation of schistosomes to overwinter
2019
International audience; Background: Global changes promote the spread of infectious diseases worldwide. In this context, tropical uro-genital schistosomiasis is now permanently established in Corsica since its first emergence in 2013. The local persistence of the tropical pathogens (schistosomes) responsible for urogenital schistosomiasis at such latitudes might be explained by (i) the presence of its intermediate host, the snail Bulinus truncatus, (ii) the recurrent local reseeding of schistosomes by their vertebrate hosts (either human or animal) every summer, and/or (iii) the maintenance and survival of schistosomes within their snail hosts over winter.Methods: In this study we conducted…
Persistance and adaptation of Listeria monocytogenes in the soil : role of the communication system Agr
2014
Listeria monocytogenes is a ubiquitous bacterium responsible for listeriosis, a food-borne disease. This pathogen has been isolated from various environments of which the telluric environment. The presence of L. monocytogenes in soil can increase health hazards due to the risk of transfer to vegetables, animals and animal products and water. Considering the role of soil in the circulation of pathogens from farm environment to plant and animal products and eventually to foodstuff, it is critical to identify intrinsic and extrinsic factors that drive the fate of L. monocytogenes in soil. Genome-wide and transcriptomic analyses found that an important part of the genome of L. monocytogenes (7.…
Psychomotor disadaptation syndrome
2020
Psychomotor disadaptation syndrome (PDS) was first described by the Geriatrics School of Dijon (France), three decades ago, under the name «psychomotor regression syndrome». Over time, the original clinical features remained unchanged. However, progress has been made in its pathophysiology understanding and care, hence the new name, PDS, appeared in the 1990s. The PDS is also called sub-cortico-frontal dysfunction syndrome since the 2000s. It corresponds to a decompensation of posture, gait and psychomotor automatisms, related to an alteration of the postural and motor programming, which is a consequence of sub-cortico-frontal lesions. The clinical features of PDS associate backward disequi…
Walk tests : a standardizable tool to assess capacities in cardio-vascular disease
2011
Cardiovascular and cerebrovascular diseases remain the first cause of mortality and handicap in the world. With the improvements in the management of the acute phase, the number of patients with limited exercise capacity due to chronic cardiovascular disease is increasing. The aim of this thesis was to conduct a thorough study of the use of standardized walk tests to assess exercise capacity in coronary artery disease patients. We first explain the concepts of handicap and quality of life in chronic diseases, and the need for functional evaluations in order to assess their impact and evolution. We then present the current modalities of cardiac rehabilitation, emphasizing the importance of p…
Étude des interconnexions dans les réseaux de régulation de Listeria monocytogenes en réponse aux conditions de l'environnement
2019
The facultative intracellular pathogen Listeria monocytogenes is a highly adaptable organism widely distributed in the environment. The ingestion of food contaminated with L. monocytogenes by at-risk individuals can ultimately lead to listeriosis, one of the leading causes of food-borne fatalities in developed countries. Regulatory networks are crucial for the adaptation and survival of this pathogen. The accessory gene regulator (Agr) system has been shown to be involved in virulence, biofilm formation, and survival of L. monocytogenes, affecting the transcription of over 700 genes. The alternative sigma factor Sigma B (σB) controls the general stress response in L. monocytogenes, regulati…
Evidence for the adaptation of bacterial populations to antibiotics degradation in agricultural soils
2013
A recent study has reported accelerated biodegradation of antibiotics in agricultural soils repeatedly amended with sewage manure contaminated by veterinary antibiotics. This pioneer work carried out by the research team directed by Dr E Topp (Agriculture and Agri-Food Canada) led to the characterization of sail microbial communities able to degrade sulfamethazine, an antibiotic belonging to sulphonamides. They showed that up to 30% of 14C0