Search results for "Addiction"
showing 10 items of 415 documents
The Life Cycle of the Mu-Opioid Receptor
2020
Opioid receptors (ORs) are undisputed targets for the treatment of pain. Unfortunately, targeting these receptors therapeutically poses significant challenges including addiction, dependence, tolerance, and the appearance of side effects, such as respiratory depression and constipation. Moreover, misuse of prescription and illicit narcotics has resulted in the current opioid crisis. The mu-opioid receptor (MOR) is the cellular mediator of the effects of most commonly used opioids, and is a prototypical G protein-coupled receptor (GPCR) where new pharmacological, signalling and cell biology concepts have been coined. This review summarises the knowledge of the life cycle of this therapeutic …
Discounting delayed monetary rewards and decision making in behavioral addictions - A comparison between patients with gambling disorder and internet…
2019
Abstract Behavior addictions, such as Gambling Disorder and Internet Gaming Disorder, have been demonstrated to have severe negative impact. Heightened impulsivity, deficits in decision making, and cognitive biases in the preference of immediate rewards have been shown to be crucial aspects in addictive disorders. While for Gambling Disorder (GD), dysfunctional decision making has been documented before, data for Internet Gaming Disorder (IGD) are still underrepresented. In order to allow for a direct comparison of both disorders, we assessed different measures of impulsivity (trait, impulsive choice, and decision making) in a clinical sample. N = 31 patients meeting criteria for GD and n =…
Addiction-Like Mobile Phone Behavior – Validation and Association With Problem Gambling
2018
Mobile phone use and its potential addiction has become a point of interest within the research community. The aim of the study was to translate and validate the Test of Mobile Dependence (TMD), and to investigate if there are any associations between mobile phone use and problem gambling. This was a cross-sectional study on a Swedish general population. A questionnaire consisting of a translated version of the TMD, three problem gambling questions (NODS-CLiP) together with two questions concerning previous addiction treatment was published online. Exploratory factor analysis based on polychoric correlations was performed on the TMD. Independent samples T-tests, Mann-Whitney test, logistic …
Analysis of DRD2 Gene Polymorphism in the Context of Personality Traits in a Group of Athletes
2021
The presented study showed the relationship between dopamine receptor gene polymorphism and personality traits in athletes training in martial arts. Behavioral modulation resulting from a balance of the neurotransmitters dopamine and norepinephrine to inactivation of the dorsolateral prefrontal cortex and dysregulation of various pathways involved in attention and impulse control processes
Why People Don’t Use Facebook Anymore? An Investigation Into the Relationship Between the Big Five Personality Traits and the Motivation to Leave Fac…
2020
This study linked the big five personality traits with motivational factors to leave Facebook based on a survey of 218 former Facebook users. The big five were related with eight main factors retrieved from existing literature. Results showed that neuroticism was positively related to addiction, banality, peer pressure, and privacy while conscientiousness was negatively related to peer pressure, addiction, annoyance, and emergence of new platforms. Openness was positively related with banality but negatively with addiction and peer pressure. Theoretical and practical interpretations are also discussed.
Mujer y juego online. Propuesta de tratamiento de un caso de adicción a videobingo
2019
Desde la legalización del juego online en España el trastorno de juego se ha incrementado notablemente, ya que ha aumentado la disponibilidad y accesibilidad de un tipo de juego que es, de por sí, más adictivo que el tradicional. Aunque las tasas de prevalencia son superiores en hombres que en mujeres, ellas no son ajenas a este problema, que también suele concurrir con otros problemas de índole emocional. El trabajo que presentamos es un estudio de caso de una mujer procedente de los servicios de salud mental, que padecía, además de adicción al juego, una importante sintomatología clínica. Se describe el protocolo de tratamiento de adicción al juego online desarrollado en la Unidad de Inve…
Addressing Dual Diagnosis Patients Suffering from Attention-Deficit Hyperactivity Disorders and Comorbid Substance Use Disorders
2013
Objective: To provide an updated, thorough, and critical review of the current status of the pharmacological and psychosocial treatments of patients with attentiondeficit hyperactivity disorder (ADHD) and a comorbid substance use disorder (SUD).
Computerspielsucht: Ein psychopathologischer Symptomkomplex im Jugendalter
2008
OBJECTIVE Cases of excessive computer gaming are increasingly reported by practitioners in the psychiatric field. Since there is no standardized definition of this symptom complex, the aim of this study is to access excessive computer gaming in German adolescents as an addictive disorder and its potential negative consequences. METHOD Psychopathological computer gaming behavior was diagnosed by applying the adapted diagnostic criteria of substance-related-addictions as defined by the ICD-10. At the same time demographic variables, state of clinical anxiety and underlying cognitive mechanisms were analyzed. RESULTS 6.3 % of the 221 participating pupils - mostly boys with a low educational ba…
P-110 - Gaming addiction - disturbed impulse control in internet addicts and pathological gamblers
2012
Internet Addiction (IA) is proposed to be added as a research diagnosis to the upcoming DSM-V while Pathological Gambling (PG) is proposed to be subsumed under the new section “Addiction and related disorders” as first behavioral addiction. The outpatient clinic for behavioral addiction of the clinic for psychosomatic medicine in Mainz offers counseling and treatment to patients suffering from IA and PG. Deficits in impulse control are suggested to be a key factor to addiction. Studies in PG have shown deficits in the ability to control impulses, for example in decision making, resisting temptation or behavioral inhibition. For Internet addiction previous research on impulse control is spar…
Binge eating and psychostimulant addiction.
2021
Many of the various factors, characteristics, and variables involved in the addictive process can determine an individual's vulnerability to develop drug addiction. Hedonic eating, based on pleasure rather than energy needs, modulates the same reward circuits, as do drugs of abuse. According to the last report of the World Health Organization, the worldwide obesity rate has more than doubled since 1980, reaching especially critical levels in children and young people, who are overexposed to high-fat, high-sugar, energy-dense foods. Over the past few decades, there has been an increase in the number of studies focused on how eating disorders can lead to the development of drug addiction and …